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The map label for this gene is ydhC [C]

Identifier: 222096928

GI number: 222096928

Start: 3212197

End: 3213396

Strand: Reverse

Name: ydhC [C]

Synonym: BCQ_3268

Alternate gene names: 222096928

Gene position: 3213396-3212197 (Counterclockwise)

Preceding gene: 222096930

Following gene: 222096927

Centisome position: 61.63

GC content: 35.42

Gene sequence:

>1200_bases
ATGAAAAAAGTCTCAGTACCATCACTTTTGTTAATGATTATTCTTGTCGCATTTCCGCAAATTAGTGAAACGATCTACAC
ACCGTCTTTACCGGACATTTCAAAGGCGTTACATGTAAGTAATAATGAGGTACAGTTAACGCTTAGTGTGTATTTTGCTG
GATTTGCTTTAGGTGTATTTTTTATTGGATGGTTATCAGATATAATTGGCCGTCGCCCGGCGATGTTATTTGGAATTGTC
GTATATGGCGTTGGGAGTTTCTTATGCTTTATTGCAAATTCCATTGAAGTTTTATTGGTAAGTCGTTTTATTCAAGCGTT
TGGAGCAAGTGCAGGATCAGTTGTGACACAAACGATTCTACGTGAAAGTGTAGAAGGGCAAAAACGCCATGTTATGTTTG
CTCAAATTTCGGCAGTTATTGCTTTTACACCGGCGATAGGACCGTTAATTGGTGGTTTTCTTGATCAAATGTTTGGATTT
AAAATCGTATTTTTAAGTTTAGTAGTAATGAGCGTCGGGATTTTTCTGTATACGTTTGTTTCTCTTCCCGAAACAAAGAC
GGACTCAGTAACGAATAAAATAAATGTGTTTTCAGTATTGAAGAGGTTAATTACAAATCCGAAAGTAGTAACATACGGGT
TATTAATTGGAGGAGCAAATGGTGTTTTATTTAGCTATTATGCAGAAGCGCCATTTATCTTTATTGAATACTTTCAGTTA
TCGCCTAGTATGTATGGATTTTTAGGAATTGTTGTTGCTTCTGCTTCTATTATTGGAGCGAAAGTTTCAAAACGATTGCT
TGCTACGTATAAACCAGAGAAAATTATATATATCGGTTGTCTCGTAATGACAGGAGGAGCTATCCTTTTGTCTGTTATTA
CGTTTGTTGGATCAAATCCAAACATAATATATATGATTGGATTTTTAGTAGCGATGTTTATATTGCTATTAGGAATTGGG
ATAGCGCTACCTAACTGTTTAAGTTTAGCATTAGTAGATTTTCAAGATGTTATTGGTACAGCCGGAGCATTGTTTAGCTT
AGGGTACTATGTAATTGTAACAATGACAATTTGGGGAATGAGTCAGCTGCATACGGGCTCGTTACTAGTGATGCCACTTT
ATTTTCTGGCTATAGTAGTTATCATGATGGTGTTTACTAAAGTGTTTATTTTAGGTAAACAAACTTCAAAAACGATTTGA

Upstream 100 bases:

>100_bases
TTGTTTTATGAGCGAATTTCTATCATGGCCCCTCCTGTTCCGTAGCTAAGGAAAGTCTTTTTATTTCTGAGATTTTCAAA
GTTATAGGAGGGTATGAAAA

Downstream 100 bases:

>100_bases
AAATAAAATGGGGACAAATCGTTATTTTGTGTAAAGGTATTAACCCTTAAGTATAAAGATAAAAATGCTCTCTCAAATTT
TTTTTGGAGAGCATTTTTGT

Product: drug resistance transporter, bcr/cfla family

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRPAMLFGIV
VYGVGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGQKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTDSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMTGGAILLSVITFVGSNPNIIYMIGFLVAMFILLLGIG
IALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFILGKQTSKTI

Sequences:

>Translated_399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRPAMLFGIV
VYGVGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGQKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTDSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMTGGAILLSVITFVGSNPNIIYMIGFLVAMFILLLGIG
IALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFILGKQTSKTI
>Mature_399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRPAMLFGIV
VYGVGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGQKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTDSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMTGGAILLSVITFVGSNPNIIYMIGFLVAMFILLLGIG
IALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTIWGMSQLHTGSLLVMPLYFLAIVVIMMVFTKVFILGKQTSKTI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=324, Percent_Identity=25.9259259259259, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1788509, Length=233, Percent_Identity=29.1845493562232, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082312, Length=327, Percent_Identity=26.9113149847095, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790146, Length=338, Percent_Identity=22.4852071005917, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787065, Length=340, Percent_Identity=24.7058823529412, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790794, Length=391, Percent_Identity=23.7851662404092, Blast_Score=68, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324264, Length=164, Percent_Identity=30.4878048780488, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43254; Mature: 43254

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVF
CCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHH
FIGWLSDIIGRRPAMLFGIVVYGVGSFLCFIANSIEVLLVSRFIQAFGASAGSVVTQTIL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
RESVEGQKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGFKIVFLSLVVMSVGIFLYTFV
HHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPETKTDSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEHHCCCCEEEEEHHHH
SPSMYGFLGIVVASASIIGAKVSKRLLATYKPEKIIYIGCLVMTGGAILLSVITFVGSNP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC
NIIYMIGFLVAMFILLLGIGIALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTIWGM
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLHTGSLLVMPLYFLAIVVIMMVFTKVFILGKQTSKTI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA