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The map label for this gene is nsr [H]

Identifier: 222096915

GI number: 222096915

Start: 3201226

End: 3201918

Strand: Reverse

Name: nsr [H]

Synonym: BCQ_3255

Alternate gene names: 222096915

Gene position: 3201918-3201226 (Counterclockwise)

Preceding gene: 222096919

Following gene: 222096914

Centisome position: 61.41

GC content: 31.75

Gene sequence:

>693_bases
ATGAAGAAAATATGTAATTCTATTAAATTAGCAGAGTATATGAAACAAAATAATATTGACTCATTTTTTAGTAATGATAT
GAAACCATATATGGAACTTATATTTTTTAAGAAGAATGAGTTTATTTGTAGAGAAAATGAAGAGATAGATTATTTATTTT
TCTTCGTTGAAGGAAAAGCGAAAGCGTTTAATACATTAAGTAACGGGAAATCTGTATTATTATGCTTTTATGATAGCTTG
CAGCTGTTAGGAGATGTGGAGTTAATTCATTCTCAAAAGACAACTTCAAACGTACAAGTGATGGCAGATTCATATTGTGT
TGGTTTGCCTTTAGGGAAAGTGAGAAATCAACTATTTCATGATGCGAAATTTTTACGATGTATTTGCGGATCGTTAGCGC
ATAAGTTAAATCGGCTTTCAAAAAATAGTACAATTAATTTACTATATCCTCTTGAAAATAGACTTGCGAGTTACATGTTA
GCAGCAGGAGAACGGGCAGTACAGCACGGAAATAGAATTGTATTTAGTGGGAATTTAACGGAAACAGCGGAATTGTTAGG
AACGAGCTATCGGCATTTGTTGCGCACATTAAATGTTTTTTGTGATAAAGAGATTATAAAGAAAAACAATGGATGCTTTG
AAGTAGTGAATGTGGATGTTTTGAGAGAATTGGCGGCAGATGTTTATAAATAA

Upstream 100 bases:

>100_bases
GACTGTATCATGCTGAAATTGTGTATTACTATGACATATGTCATAGTGGAAGGAGAAAATTTTGATTACAATGGGGAGTA
GTTGCAAAGGCGGGGGAACT

Downstream 100 bases:

>100_bases
TATAGTAAAGTGGGGATTTAGATGAAAATAGCAATCATTTCAGATGTTCACGGAAATAGTCACGCTTTACAAGCAGTATT
AAAAGATATTGCACGTCGTA

Product: cyclic nucleotide-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKKICNSIKLAEYMKQNNIDSFFSNDMKPYMELIFFKKNEFICRENEEIDYLFFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQKTTSNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAVQHGNRIVFSGNLTETAELLGTSYRHLLRTLNVFCDKEIIKKNNGCFEVVNVDVLRELAADVYK

Sequences:

>Translated_230_residues
MKKICNSIKLAEYMKQNNIDSFFSNDMKPYMELIFFKKNEFICRENEEIDYLFFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQKTTSNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAVQHGNRIVFSGNLTETAELLGTSYRHLLRTLNVFCDKEIIKKNNGCFEVVNVDVLRELAADVYK
>Mature_230_residues
MKKICNSIKLAEYMKQNNIDSFFSNDMKPYMELIFFKKNEFICRENEEIDYLFFFVEGKAKAFNTLSNGKSVLLCFYDSL
QLLGDVELIHSQKTTSNVQVMADSYCVGLPLGKVRNQLFHDAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYML
AAGERAVQHGNRIVFSGNLTETAELLGTSYRHLLRTLNVFCDKEIIKKNNGCFEVVNVDVLRELAADVYK

Specific function: Transcription regulator involved in mid-term, stationary-phase viability under nitrogen starvation. Might control expression of the salvage pathways or in some other way repress the recycling of nucleobases to nucleic acids and enhance their use as genera

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788487, Length=215, Percent_Identity=30.6976744186047, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR012318
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding [H]

EC number: NA

Molecular weight: Translated: 26326; Mature: 26326

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKICNSIKLAEYMKQNNIDSFFSNDMKPYMELIFFKKNEFICRENEEIDYLFFFVEGKA
CCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCEEECCCCCEEEEEEEEECCH
KAFNTLSNGKSVLLCFYDSLQLLGDVELIHSQKTTSNVQVMADSYCVGLPLGKVRNQLFH
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCEEEEECCEEECCCHHHHHHHHHH
DAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYMLAAGERAVQHGNRIVFSGNLT
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEECCCH
ETAELLGTSYRHLLRTLNVFCDKEIIKKNNGCFEVVNVDVLRELAADVYK
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKICNSIKLAEYMKQNNIDSFFSNDMKPYMELIFFKKNEFICRENEEIDYLFFFVEGKA
CCHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCEEECCCCCEEEEEEEEECCH
KAFNTLSNGKSVLLCFYDSLQLLGDVELIHSQKTTSNVQVMADSYCVGLPLGKVRNQLFH
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCEEEEECCEEECCCHHHHHHHHHH
DAKFLRCICGSLAHKLNRLSKNSTINLLYPLENRLASYMLAAGERAVQHGNRIVFSGNLT
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCEEEEECCCH
ETAELLGTSYRHLLRTLNVFCDKEIIKKNNGCFEVVNVDVLRELAADVYK
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]