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The map label for this gene is mutT [H]

Identifier: 222096787

GI number: 222096787

Start: 3083061

End: 3083507

Strand: Reverse

Name: mutT [H]

Synonym: BCQ_3127

Alternate gene names: 222096787

Gene position: 3083507-3083061 (Counterclockwise)

Preceding gene: 222096788

Following gene: 222096786

Centisome position: 59.14

GC content: 30.65

Gene sequence:

>447_bases
ATGAATACTATAAAAACCACAGGGTGCTTTACTATTGTTGATAATAATGAAGGCAAAATATTGCTAGTTAAACGAAATGA
TTATCCTATCTGGGATTTGCCTGGGGGAAGATTAGAAGAGAACGAACAGTTAGATAAATGCGCTATAAGAGAAACTGAAG
AAGAAACGGGCTATATAATTGCTATTGAACGTAAAATAGGAGAATATCACCAGCCTGAATACAATGATATGCAACATATA
TTTTCAGGAAAATTACTAGGAGGAGAACCAATAAATAATGGACCTGAAACTGCAAAAATTGGATGGTTTAATCCTAGTAG
ATTACCTTTTTTAATGGTTCCAAATAGAAAAAAACAGATCAATAATTTTATGAAACACAAAAATTCACTAATAAAAGAGA
CATTAAAGACACCATTTATGGTAAAGGTATTGAAAAAAATTATGTGA

Upstream 100 bases:

>100_bases
ATTAAAGGGCCAGTTTAATTCAGCAAAAAGGAAAATTTATTAGACATAGAGAAATACAAGTTTGTTAGCAATTGAGTAAG
TTAAGGAGATTATATTTATA

Downstream 100 bases:

>100_bases
GATGGTTATTGAATTAACGGGTGCTTTTCTTGAATAAGGATCAGTTCTTAATTTCTTGTATCTATCAAAAAAGATAATTT
GTACTTCCGACTTCGAAAGT

Product: mutt/nudix family protein

Products: NA

Alternate protein names: 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 148; Mature: 148

Protein sequence:

>148_residues
MNTIKTTGCFTIVDNNEGKILLVKRNDYPIWDLPGGRLEENEQLDKCAIRETEEETGYIIAIERKIGEYHQPEYNDMQHI
FSGKLLGGEPINNGPETAKIGWFNPSRLPFLMVPNRKKQINNFMKHKNSLIKETLKTPFMVKVLKKIM

Sequences:

>Translated_148_residues
MNTIKTTGCFTIVDNNEGKILLVKRNDYPIWDLPGGRLEENEQLDKCAIRETEEETGYIIAIERKIGEYHQPEYNDMQHI
FSGKLLGGEPINNGPETAKIGWFNPSRLPFLMVPNRKKQINNFMKHKNSLIKETLKTPFMVKVLKKIM
>Mature_148_residues
MNTIKTTGCFTIVDNNEGKILLVKRNDYPIWDLPGGRLEENEQLDKCAIRETEEETGYIIAIERKIGEYHQPEYNDMQHI
FSGKLLGGEPINNGPETAKIGWFNPSRLPFLMVPNRKKQINNFMKHKNSLIKETLKTPFMVKVLKKIM

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo- dGTP is inserted opposite dA and dC residues of template DNA with almost equa

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 17135; Mature: 17135

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTIKTTGCFTIVDNNEGKILLVKRNDYPIWDLPGGRLEENEQLDKCAIRETEEETGYII
CCCCCCCEEEEEEECCCCEEEEEECCCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCEEE
AIERKIGEYHQPEYNDMQHIFSGKLLGGEPINNGPETAKIGWFNPSRLPFLMVPNRKKQI
EEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCEEEECCCCHHHH
NNFMKHKNSLIKETLKTPFMVKVLKKIM
HHHHHHHHHHHHHHHCCCHHHHHHHHHC
>Mature Secondary Structure
MNTIKTTGCFTIVDNNEGKILLVKRNDYPIWDLPGGRLEENEQLDKCAIRETEEETGYII
CCCCCCCEEEEEEECCCCEEEEEECCCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCEEE
AIERKIGEYHQPEYNDMQHIFSGKLLGGEPINNGPETAKIGWFNPSRLPFLMVPNRKKQI
EEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCEEEECCCCHHHH
NNFMKHKNSLIKETLKTPFMVKVLKKIM
HHHHHHHHHHHHHHHCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]