Click here to switch to the map view.

The map label for this gene is lutA1 [H]

Identifier: 222096727

GI number: 222096727

Start: 3025082

End: 3025810

Strand: Reverse

Name: lutA1 [H]

Synonym: BCQ_3067

Alternate gene names: 222096727

Gene position: 3025810-3025082 (Counterclockwise)

Preceding gene: 222096729

Following gene: 222096726

Centisome position: 58.03

GC content: 37.31

Gene sequence:

>729_bases
ATGAAAGTCTCGTTATTTATTACTTGTTTATCAGATGTGTTTTTTCCTGAAGTAGGTAAAAGTGTCGTAGAAATTATGAA
TCAATGTGGAGTGGAACTAGATTTCCCTGAAGGACAGACTTGTTGCGGACAACCAGCTTACAATAGTGGATATCAAGAAG
ATGCAAAACTAGCAGCAAAGCAAATGATTAAAGCATTTGAACATAGTGAATATATTGTGACCCCTTCAGGTTCTTGCGCT
AGCATGGTTCATCATTATTATAAAGAGATGTTTAAAGGTGATAGTGAATGGTATGAAAAAGCAGTTCATTTAGCGGATAG
AACGTATGAGTTGACGGACTTTTTAGTGAATGTACTTGGGAAAAATAATTGGAAATCTAAGTTGGTTGAGAAAGCTGTTT
TCCATCAATCTTGTCATATGAGTCGGGCGCTCGGGATCAAAGAGGAACCACTGAAGTTATTATCGCAAGTAGAAGGTCTA
GACATAAAAGAGTTACCATATTGCCAAGATTGCTGCGGGTTTGGTGGTACTTTTGCAGTGAAAATGAGCTCGATTTCTGA
AACGATGGTTGATGAAAAAATAAAACATATTGAGGCGACAGAAGCAAATCTCTTAATTGGAGCAGATATGGGATGTCTTA
TGAATATTGGGGGAAGATTGCGTAGGAAAAATAAAAATATTCAAGTGTTACATGTAGCAGAAGTACTGGCGAAGGGGCTG
AGTAAATGA

Upstream 100 bases:

>100_bases
AACAAAAAGTTTTAAAAATAGAAAATTCTAAAAATTTAAAATAATTTTCGGGAAAGTAATAACTTGAAAATAGATCATAT
CGTTTTGAGGGGGGATTTTG

Downstream 100 bases:

>100_bases
GTGTGGCGGGGGAACTAGATTTTTTGAAAAGAGTAGATAAAGCGTTGCATGATCCGCAGATGAGAAGCGCGGTTCCGTTT
ACACAAGATCGGCTTCGGAT

Product: (s)-2-hydroxy-acid oxidase, iron-sulfur subunit

Products: 2-oxo acid; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKVSLFITCLSDVFFPEVGKSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAKQMIKAFEHSEYIVTPSGSCA
SMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNVLGKNNWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGL
DIKELPYCQDCCGFGGTFAVKMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRKNKNIQVLHVAEVLAKGL
SK

Sequences:

>Translated_242_residues
MKVSLFITCLSDVFFPEVGKSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAKQMIKAFEHSEYIVTPSGSCA
SMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNVLGKNNWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGL
DIKELPYCQDCCGFGGTFAVKMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRKNKNIQVLHVAEVLAKGL
SK
>Mature_242_residues
MKVSLFITCLSDVFFPEVGKSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAKQMIKAFEHSEYIVTPSGSCA
SMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNVLGKNNWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGL
DIKELPYCQDCCGFGGTFAVKMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRKNKNIQVLHVAEVLAKGL
SK

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lutA/ykgE family [H]

Homologues:

Organism=Escherichia coli, GI1786497, Length=237, Percent_Identity=42.6160337552743, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI48994913, Length=250, Percent_Identity=22, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788576, Length=249, Percent_Identity=23.2931726907631, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004017
- InterPro:   IPR022822 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: 1.1.3.15

Molecular weight: Translated: 27019; Mature: 27019

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSLFITCLSDVFFPEVGKSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAK
CCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHH
QMIKAFEHSEYIVTPSGSCASMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNVLG
HHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
KNNWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGLDIKELPYCQDCCGFGGTFAV
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEE
KMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRKNKNIQVLHVAEVLAKGL
EHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHC
SK
CC
>Mature Secondary Structure
MKVSLFITCLSDVFFPEVGKSVVEIMNQCGVELDFPEGQTCCGQPAYNSGYQEDAKLAAK
CCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHH
QMIKAFEHSEYIVTPSGSCASMVHHYYKEMFKGDSEWYEKAVHLADRTYELTDFLVNVLG
HHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
KNNWKSKLVEKAVFHQSCHMSRALGIKEEPLKLLSQVEGLDIKELPYCQDCCGFGGTFAV
CCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEE
KMSSISETMVDEKIKHIEATEANLLIGADMGCLMNIGGRLRRKNKNIQVLHVAEVLAKGL
EHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHC
SK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-hydroxy acid; O2

Specific reaction: (S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA