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The map label for this gene is arsR [H]

Identifier: 222096670

GI number: 222096670

Start: 2960837

End: 2961301

Strand: Reverse

Name: arsR [H]

Synonym: BCQ_3010

Alternate gene names: 222096670

Gene position: 2961301-2960837 (Counterclockwise)

Preceding gene: 222096671

Following gene: 222096669

Centisome position: 56.79

GC content: 30.75

Gene sequence:

>465_bases
TTGTTGAAAAAGCTATGGTCTTTTTTTATTGTAACAAAGATAGGATGCGAGGAAGTTTTTTGTAAATCAAAAAAACTTGA
TGAACTAGTTGCATATAAAACTCATCTGCGTATATACTATATATATCAAAAAAAATTGATGAAGGGAGAGGAAACTACAG
TGGCACAGGATTTTAAGTTATATGAGAAAAAGTTTAAAGCGTTGGCGGATCAAAAGCGATTAGAGATTATGTATGAACTT
TGCCAGCGAGGCCAGACTTGTGTATGTGATTTAACAGAGATTTTTGAAATGACGCAATCTAAGTTGTCCTATCATTTAAA
GATTTTATTAGATGCAGGTTTAATTGTAAAAGAAACAAAAGGTACGTGGAGTTATTATGATTTAAATGATGCGGAAGTAA
ATAATTTATTATCAGAAGAATTGTGCTGTATTTTTAGAAAAACAGGAAAAGGTAGCTGTTGTTAA

Upstream 100 bases:

>100_bases
TACTCTATAATGGTCAAATTAAAATTTAAAACAGTTATAGAGACTCCACCACTGGGGAAGATTATAACTATCAAGTTGTA
AAAAGAACTGTAGTTTTTCA

Downstream 100 bases:

>100_bases
AATTTTGCGCTATTAATCAAAAAAACTTGATCAATGACATATAAAGAGGAGGAATAAGGTATGAGATATGTTCACGTTGG
TATAAATGTTACGAATTTAG

Product: arsenical resistance operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MLKKLWSFFIVTKIGCEEVFCKSKKLDELVAYKTHLRIYYIYQKKLMKGEETTVAQDFKLYEKKFKALADQKRLEIMYEL
CQRGQTCVCDLTEIFEMTQSKLSYHLKILLDAGLIVKETKGTWSYYDLNDAEVNNLLSEELCCIFRKTGKGSCC

Sequences:

>Translated_154_residues
MLKKLWSFFIVTKIGCEEVFCKSKKLDELVAYKTHLRIYYIYQKKLMKGEETTVAQDFKLYEKKFKALADQKRLEIMYEL
CQRGQTCVCDLTEIFEMTQSKLSYHLKILLDAGLIVKETKGTWSYYDLNDAEVNNLLSEELCCIFRKTGKGSCC
>Mature_154_residues
MLKKLWSFFIVTKIGCEEVFCKSKKLDELVAYKTHLRIYYIYQKKLMKGEETTVAQDFKLYEKKFKALADQKRLEIMYEL
CQRGQTCVCDLTEIFEMTQSKLSYHLKILLDAGLIVKETKGTWSYYDLNDAEVNNLLSEELCCIFRKTGKGSCC

Specific function: Transcriptional repressor for the ars operon [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=73, Percent_Identity=39.7260273972603, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 18079; Mature: 18079

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
5.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKLWSFFIVTKIGCEEVFCKSKKLDELVAYKTHLRIYYIYQKKLMKGEETTVAQDFKL
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHCCCCHHHHHHHHH
YEKKFKALADQKRLEIMYELCQRGQTCVCDLTEIFEMTQSKLSYHLKILLDAGLIVKETK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHEEECCEEEEECC
GTWSYYDLNDAEVNNLLSEELCCIFRKTGKGSCC
CCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLKKLWSFFIVTKIGCEEVFCKSKKLDELVAYKTHLRIYYIYQKKLMKGEETTVAQDFKL
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHCCCCHHHHHHHHH
YEKKFKALADQKRLEIMYELCQRGQTCVCDLTEIFEMTQSKLSYHLKILLDAGLIVKETK
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHEEECCEEEEECC
GTWSYYDLNDAEVNNLLSEELCCIFRKTGKGSCC
CCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]