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The map label for this gene is acdA [H]

Identifier: 222096574

GI number: 222096574

Start: 2848044

End: 2849192

Strand: Reverse

Name: acdA [H]

Synonym: BCQ_2914

Alternate gene names: 222096574

Gene position: 2849192-2848044 (Counterclockwise)

Preceding gene: 222096575

Following gene: 222096571

Centisome position: 54.64

GC content: 40.3

Gene sequence:

>1149_bases
ATGGCACTCTCATTTGTTGAAACAGAAAAACAATCTTTCATTATTGAACAAATAAATAAATTGATTCCGAAGTTCATGGA
AAGGGAGCATCAACTAAGTGAATTAGGATCATTTCCGTATGAAAATATAAATGATTTGAAAGATATCGGATATACGAAAT
TAACGTTACCGAAGGAATTTGGTGGTAGTGCGATTTCTTTATATGACTTCGTTCTATTTCAAGAGAAAATTGCGGAAGGC
TGCGGGGCTACTGCATTATCGATTGGCTGGCATCTTGGCATTGTGAAAGAACTAGCGGAAAATCGCTCTTGGAATGATGA
GATGTTTAAATGGTTTTGCGAAGAAGTGCGAAATGGGGCGCTCTTTAATAGGGCAGCAACAGAACCGAAAACAGGGAGTC
CGACGCGTGGCGGTAAACCAGAAACAATAGCGGTTCAACAAGGCGAGAAGTGGGTTATAAATGGAAGGAAAACTTTTACA
ACGATGGCGCCAGTACTTGATTATTTTATTATTTCAGCGAGTATGGAAGGCCGTGAAGAAGTTGGTGAGTTTGTTATTCC
AAGAAATACAATCGGTGTATCCATTGAAGAAACGTGGGATAGCGTTGCGATGCGAGGGACTGCTAGCCACGACCTTGTCT
TACAAAATGTAGAGATAGACAACCGCTTTTTTACGGATGTAAAAGGCGGGAAAGTGAAACAAAAGGGTATTGGCTGGTTG
CTACATATACCAGCATGTTATTTAGGAATTGCACAATCAGCAAGAAATTATGCAGTTCAGTTTGCGGGATCATACAAACC
AAATAGTTTAAACCATTCTATTAGTTTATTACCGAATGTTAGAAGATTAGTTGGAGAATTAGAACTCGAGCTTATGCAAG
CTCGCGTCTTTTTATATCAAATTGCGAAAAAATACGATGAGGCAGAAGATAAACTGTCACTGCAAGCAGAATTAGCGGCA
GTGAAATACGCCGTAACAAATGCGGCGATATCCATAGTGGATAAATCAATGCGCATCGTAGGAGCAAAAAGTTTATCAGA
AAAAAATCCGCTTCACCGTTATTATTTAAACGTTAGAGCAGGACTACACAACCCGCCGATGGATGATGCAACACTATCTA
TGTTGGCGGATGCGGCGTTTCGGTCGTAG

Upstream 100 bases:

>100_bases
TGTATTTTTATCGGAATAGTGAAACAATAGAGAGGTAGCTTCATATAATCATAATGACAAAATGAACGGTTTATGAATCG
AACATAAAGGAGATTATAGT

Downstream 100 bases:

>100_bases
TTTTTTTAGCTTGAACTTTATTATTTAAGTACAATATAGTTGTTTTGAAAGCACGTGTTTGATTAGTAATCGAACGCGTG
CTTTTTATTCGATTGATATA

Product: acyl-CoA dehydrogenase, short-chain specific

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MALSFVETEKQSFIIEQINKLIPKFMEREHQLSELGSFPYENINDLKDIGYTKLTLPKEFGGSAISLYDFVLFQEKIAEG
CGATALSIGWHLGIVKELAENRSWNDEMFKWFCEEVRNGALFNRAATEPKTGSPTRGGKPETIAVQQGEKWVINGRKTFT
TMAPVLDYFIISASMEGREEVGEFVIPRNTIGVSIEETWDSVAMRGTASHDLVLQNVEIDNRFFTDVKGGKVKQKGIGWL
LHIPACYLGIAQSARNYAVQFAGSYKPNSLNHSISLLPNVRRLVGELELELMQARVFLYQIAKKYDEAEDKLSLQAELAA
VKYAVTNAAISIVDKSMRIVGAKSLSEKNPLHRYYLNVRAGLHNPPMDDATLSMLADAAFRS

Sequences:

>Translated_382_residues
MALSFVETEKQSFIIEQINKLIPKFMEREHQLSELGSFPYENINDLKDIGYTKLTLPKEFGGSAISLYDFVLFQEKIAEG
CGATALSIGWHLGIVKELAENRSWNDEMFKWFCEEVRNGALFNRAATEPKTGSPTRGGKPETIAVQQGEKWVINGRKTFT
TMAPVLDYFIISASMEGREEVGEFVIPRNTIGVSIEETWDSVAMRGTASHDLVLQNVEIDNRFFTDVKGGKVKQKGIGWL
LHIPACYLGIAQSARNYAVQFAGSYKPNSLNHSISLLPNVRRLVGELELELMQARVFLYQIAKKYDEAEDKLSLQAELAA
VKYAVTNAAISIVDKSMRIVGAKSLSEKNPLHRYYLNVRAGLHNPPMDDATLSMLADAAFRS
>Mature_381_residues
ALSFVETEKQSFIIEQINKLIPKFMEREHQLSELGSFPYENINDLKDIGYTKLTLPKEFGGSAISLYDFVLFQEKIAEGC
GATALSIGWHLGIVKELAENRSWNDEMFKWFCEEVRNGALFNRAATEPKTGSPTRGGKPETIAVQQGEKWVINGRKTFTT
MAPVLDYFIISASMEGREEVGEFVIPRNTIGVSIEETWDSVAMRGTASHDLVLQNVEIDNRFFTDVKGGKVKQKGIGWLL
HIPACYLGIAQSARNYAVQFAGSYKPNSLNHSISLLPNVRRLVGELELELMQARVFLYQIAKKYDEAEDKLSLQAELAAV
KYAVTNAAISIVDKSMRIVGAKSLSEKNPLHRYYLNVRAGLHNPPMDDATLSMLADAAFRS

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=332, Percent_Identity=22.8915662650602, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI226958412, Length=351, Percent_Identity=21.9373219373219, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI226958414, Length=319, Percent_Identity=21.9435736677116, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=318, Percent_Identity=24.2138364779874, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17508101, Length=358, Percent_Identity=20.9497206703911, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=315, Percent_Identity=20.952380952381, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21356377, Length=343, Percent_Identity=23.0320699708455, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646207, Length=349, Percent_Identity=24.3553008595989, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355753, Length=319, Percent_Identity=23.1974921630094, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24666513, Length=368, Percent_Identity=22.8260869565217, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013107
- InterPro:   IPR006092
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF08028 Acyl-CoA_dh_2; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42726; Mature: 42595

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSFVETEKQSFIIEQINKLIPKFMEREHQLSELGSFPYENINDLKDIGYTKLTLPKEF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEECCHHH
GGSAISLYDFVLFQEKIAEGCGATALSIGWHLGIVKELAENRSWNDEMFKWFCEEVRNGA
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
LFNRAATEPKTGSPTRGGKPETIAVQQGEKWVINGRKTFTTMAPVLDYFIISASMEGREE
EECCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCCHHH
VGEFVIPRNTIGVSIEETWDSVAMRGTASHDLVLQNVEIDNRFFTDVKGGKVKQKGIGWL
HCCEECCCCCEEEEHHHHHHHHHHCCCCCCCEEEEEEEECCEEECCCCCCEEECCCCCEE
LHIPACYLGIAQSARNYAVQFAGSYKPNSLNHSISLLPNVRRLVGELELELMQARVFLYQ
EEHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAKKYDEAEDKLSLQAELAAVKYAVTNAAISIVDKSMRIVGAKSLSEKNPLHRYYLNVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
GLHNPPMDDATLSMLADAAFRS
CCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALSFVETEKQSFIIEQINKLIPKFMEREHQLSELGSFPYENINDLKDIGYTKLTLPKEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEECCHHH
GGSAISLYDFVLFQEKIAEGCGATALSIGWHLGIVKELAENRSWNDEMFKWFCEEVRNGA
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
LFNRAATEPKTGSPTRGGKPETIAVQQGEKWVINGRKTFTTMAPVLDYFIISASMEGREE
EECCCCCCCCCCCCCCCCCCCEEEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCCHHH
VGEFVIPRNTIGVSIEETWDSVAMRGTASHDLVLQNVEIDNRFFTDVKGGKVKQKGIGWL
HCCEECCCCCEEEEHHHHHHHHHHCCCCCCCEEEEEEEECCEEECCCCCCEEECCCCCEE
LHIPACYLGIAQSARNYAVQFAGSYKPNSLNHSISLLPNVRRLVGELELELMQARVFLYQ
EEHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAKKYDEAEDKLSLQAELAAVKYAVTNAAISIVDKSMRIVGAKSLSEKNPLHRYYLNVRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEC
GLHNPPMDDATLSMLADAAFRS
CCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]