Click here to switch to the map view.

The map label for this gene is marA [H]

Identifier: 222096528

GI number: 222096528

Start: 2806885

End: 2807775

Strand: Reverse

Name: marA [H]

Synonym: BCQ_2868

Alternate gene names: 222096528

Gene position: 2807775-2806885 (Counterclockwise)

Preceding gene: 222096529

Following gene: 222096527

Centisome position: 53.85

GC content: 34.57

Gene sequence:

>891_bases
ATGGAGAATAAACAAAGTAGAAATGAGTATGTAAGATGCATACATACAGTTCAAGATTATATAGAATCCAACATAGATAG
TTCACTATCCATTGAAGAGCTAGCCAATGTAGCAGGATTTTCAAAGTTTCATTTTCATAGAATTTTTAAAGGAATAGTAG
ACGAGCCGTTATCTCGGTATGTGAATCGCTTGAAGTTAGAAAGGGCAACAAACCTTCTTACATACCGTTCGGATATGACG
ATTACTGACATCGCTTACCATTTTGGTTTCACAGATTCGGCAGTTTTCTCCCGTACATTTAAAAATTATTACGGAGTAAG
TCCGTCTCAATATCGAAACCATAATAGCAAGAATTGCAAAGACGTAAGAAGAACTTCTCAATACAATGAATGTAAGAAGG
TTCGAGGAAATGTTGAAATTGTAACAGCGGACGATATAAACGTTGCATACATAAGACATATCGGTACATATAGGGAGTTA
ACTATAGCTTTTCCAAAAATGATAGAGAAATTATTTCATTACGCAGCTAAGCAAAACTATCATGTATTTGAGGATACGAA
AGTATTAACCATTTACCACGATCATCATGAATTTACAGAGGACTATCAGTTAAGGACTAGTTTATGTATAACAATTCCGG
ATGAATCCGCAGTAGAAACGAACAACATTGGAATAATGGTAATACCTTCTGGAAAGTATGCGGTAAGTCATTTTGAAATA
CAACAAGATGAATATAAAGGAGCATGGGATTTTTTATACGGTGAATGGCTACCAAATAGCGGATATAAACCGAGAGATGC
GTATCCTTTTGAAATGTATAAAAATGACCCAAGGCAGCACCCAGAAAATAAACATATAGTTGATATATATGTACCTATCG
AACCTTTTTAA

Upstream 100 bases:

>100_bases
AATTATGATGGGAACGGCGGTAGTAGAGTTTTATTTTTGAAACAGGTGTAAAAGTAGGCTAGCGAAAAGTTAGCCTTTTT
GTTGTGAGGAGATAACAAGT

Downstream 100 bases:

>100_bases
TTATAGGTTAAAGGGGAAGGAATAATGAAAACTGCTGAAAAGTTAGATCAGATTATACAAGAAGAATATAAAAACATGAA
TGGTATGTTAGTAGTGCAGA

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MENKQSRNEYVRCIHTVQDYIESNIDSSLSIEELANVAGFSKFHFHRIFKGIVDEPLSRYVNRLKLERATNLLTYRSDMT
ITDIAYHFGFTDSAVFSRTFKNYYGVSPSQYRNHNSKNCKDVRRTSQYNECKKVRGNVEIVTADDINVAYIRHIGTYREL
TIAFPKMIEKLFHYAAKQNYHVFEDTKVLTIYHDHHEFTEDYQLRTSLCITIPDESAVETNNIGIMVIPSGKYAVSHFEI
QQDEYKGAWDFLYGEWLPNSGYKPRDAYPFEMYKNDPRQHPENKHIVDIYVPIEPF

Sequences:

>Translated_296_residues
MENKQSRNEYVRCIHTVQDYIESNIDSSLSIEELANVAGFSKFHFHRIFKGIVDEPLSRYVNRLKLERATNLLTYRSDMT
ITDIAYHFGFTDSAVFSRTFKNYYGVSPSQYRNHNSKNCKDVRRTSQYNECKKVRGNVEIVTADDINVAYIRHIGTYREL
TIAFPKMIEKLFHYAAKQNYHVFEDTKVLTIYHDHHEFTEDYQLRTSLCITIPDESAVETNNIGIMVIPSGKYAVSHFEI
QQDEYKGAWDFLYGEWLPNSGYKPRDAYPFEMYKNDPRQHPENKHIVDIYVPIEPF
>Mature_296_residues
MENKQSRNEYVRCIHTVQDYIESNIDSSLSIEELANVAGFSKFHFHRIFKGIVDEPLSRYVNRLKLERATNLLTYRSDMT
ITDIAYHFGFTDSAVFSRTFKNYYGVSPSQYRNHNSKNCKDVRRTSQYNECKKVRGNVEIVTADDINVAYIRHIGTYREL
TIAFPKMIEKLFHYAAKQNYHVFEDTKVLTIYHDHHEFTEDYQLRTSLCITIPDESAVETNNIGIMVIPSGKYAVSHFEI
QQDEYKGAWDFLYGEWLPNSGYKPRDAYPFEMYKNDPRQHPENKHIVDIYVPIEPF

Specific function: May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF [H]

COG id: COG3449

COG function: function code L; DNA gyrase inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081928, Length=109, Percent_Identity=35.7798165137615, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34864; Mature: 34864

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKQSRNEYVRCIHTVQDYIESNIDSSLSIEELANVAGFSKFHFHRIFKGIVDEPLSRY
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VNRLKLERATNLLTYRSDMTITDIAYHFGFTDSAVFSRTFKNYYGVSPSQYRNHNSKNCK
HHHHHHHHHHHHEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCHH
DVRRTSQYNECKKVRGNVEIVTADDINVAYIRHIGTYRELTIAFPKMIEKLFHYAAKQNY
HHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
HVFEDTKVLTIYHDHHEFTEDYQLRTSLCITIPDESAVETNNIGIMVIPSGKYAVSHFEI
EEECCCEEEEEEECCCHHCHHHEEEEEEEEECCCCCCEEECCEEEEEEECCCEEEEEEEE
QQDEYKGAWDFLYGEWLPNSGYKPRDAYPFEMYKNDPRQHPENKHIVDIYVPIEPF
CHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MENKQSRNEYVRCIHTVQDYIESNIDSSLSIEELANVAGFSKFHFHRIFKGIVDEPLSRY
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VNRLKLERATNLLTYRSDMTITDIAYHFGFTDSAVFSRTFKNYYGVSPSQYRNHNSKNCK
HHHHHHHHHHHHEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCHH
DVRRTSQYNECKKVRGNVEIVTADDINVAYIRHIGTYRELTIAFPKMIEKLFHYAAKQNY
HHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
HVFEDTKVLTIYHDHHEFTEDYQLRTSLCITIPDESAVETNNIGIMVIPSGKYAVSHFEI
EEECCCEEEEEEECCCHHCHHHEEEEEEEEECCCCCCEEECCEEEEEEECCCEEEEEEEE
QQDEYKGAWDFLYGEWLPNSGYKPRDAYPFEMYKNDPRQHPENKHIVDIYVPIEPF
CHHHCCCHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]