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The map label for this gene is adP [C]

Identifier: 222096503

GI number: 222096503

Start: 2783771

End: 2784937

Strand: Reverse

Name: adP [C]

Synonym: BCQ_2843

Alternate gene names: 222096503

Gene position: 2784937-2783771 (Counterclockwise)

Preceding gene: 222096504

Following gene: 222096502

Centisome position: 53.41

GC content: 38.56

Gene sequence:

>1167_bases
ATGAAAAAACGTAATCCAATGAAGTTAGCAAGTTTGGCAGTTTTATTAGCGGGTACCACTGTATTCACACCAGGTTTTAC
TGTAAAAGCAGAGTCTACTCAAAATATTTCTAATTCGTCAGAAGCACATGATCAAAAGAATCGGAATGGTTGGAAAAGGG
TCATGCAGGAAACAATTCAAATTGGAGCGCCAGGGGTATTAGCTAAGACGTCTAATAAAGGGAAAATTAGTAGTTATACT
GCTGGCGTAGCAGATTTAAGCACAAAGAAACCGGTGAAATCAGATTATCGCTTTCGAATTGGTAGTGTGACGAAAACTTT
TACCGCCACGACGGTTCTTCAATTAGTTGGAGAAAATCGCGTACAACTTGACGATTCAATTGAGAAGTGGTTACCGGGTC
TCGTTCAAGGAAATGGGTATGATGGCAATCAAATTACGATACGCCAACTTTTGAATCATACAAGTGGTATCGCTGAATAC
TTAAAGTCAAAAGATGCTGACATAATGAATTCGAAAAAAACGTATACAGCTGAAGAAATAGTGAAAATAGGTCTTTCTCT
ACCTCCAGATTTCTCGCCGGGTAAAGACTGGTTGTATTCAAACACAGGATACGTAATACTAGGAATGCTTATTGAAAAAA
TAACTGGTAATAGTTATGCGGAAGAAATTGAAAAGCGAATTATTGAACCTCTGGACTTGCCAAATACGTTTTTACCAGGA
AATTCACCCGTCATCCCAGGAAAGAATCATGCTCGTGGATATGTGAAAATGGACGAAACAGGCGAGTTGAAAGACATTAC
GTATTATAATCCGAGTTTAGCTAATGCAGCTGGAGATATGATTTCTAATGCGGATGATTTAAACAAGTTCTTTTCATCTT
TACTCGGTGGTAAGTTACTGAAGGAACGCGAGTTAAAAGAAATGCTTACTACAGTTCCTATAGAAGGAAAAGGGGTTGGT
GATGGATATGGCCTTGGAATCTATGAGACGAAACTTCCAAATGGTGTCTCAGTTTGGGGGCACGGAGGATCAATTCCTGG
GTTTATGACTTTTGCTGGTGGAGTAATTGGAGGCAAGCATACATTTGCTGTCAATGCTAATTCTTTAGGTCCGGTTGAAA
TCCTTACACAGTTTAATAAAATGATGCAAGTTGAATTTAATAAATAG

Upstream 100 bases:

>100_bases
AGTATTTTGTAAGGAATGGATAAGAAAAAAGAGAGTTTTATCATATAGGATAAAAGTATATTTCGAATCAAAATGATATG
AATAGGGGAGAGAGAATCTT

Downstream 100 bases:

>100_bases
ATGAAGAAAAAGCGAATAGGTTTCTGCGATAGTTTTAAATAAAAGAGATGCTTTTTAAATTTCACAAATAAGGACAGTAT
TAACATTCATGATATGGTAT

Product: alkaline d-peptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKKRNPMKLASLAVLLAGTTVFTPGFTVKAESTQNISNSSEAHDQKNRNGWKRVMQETIQIGAPGVLAKTSNKGKISSYT
AGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENRVQLDDSIEKWLPGLVQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLSLPPDFSPGKDWLYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
NSPVIPGKNHARGYVKMDETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPIEGKGVG
DGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKHTFAVNANSLGPVEILTQFNKMMQVEFNK

Sequences:

>Translated_388_residues
MKKRNPMKLASLAVLLAGTTVFTPGFTVKAESTQNISNSSEAHDQKNRNGWKRVMQETIQIGAPGVLAKTSNKGKISSYT
AGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENRVQLDDSIEKWLPGLVQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLSLPPDFSPGKDWLYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
NSPVIPGKNHARGYVKMDETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPIEGKGVG
DGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKHTFAVNANSLGPVEILTQFNKMMQVEFNK
>Mature_388_residues
MKKRNPMKLASLAVLLAGTTVFTPGFTVKAESTQNISNSSEAHDQKNRNGWKRVMQETIQIGAPGVLAKTSNKGKISSYT
AGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENRVQLDDSIEKWLPGLVQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLSLPPDFSPGKDWLYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
NSPVIPGKNHARGYVKMDETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPIEGKGVG
DGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKHTFAVNANSLGPVEILTQFNKMMQVEFNK

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=266, Percent_Identity=26.6917293233083, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082101, Length=254, Percent_Identity=25.9842519685039, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17550934, Length=314, Percent_Identity=27.7070063694268, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI115533026, Length=404, Percent_Identity=26.2376237623762, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17565630, Length=293, Percent_Identity=27.3037542662116, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42179; Mature: 42179

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRNPMKLASLAVLLAGTTVFTPGFTVKAESTQNISNSSEAHDQKNRNGWKRVMQETIQ
CCCCCCHHHHHHHHHHHCCEEECCCEEEEECCCCCCCCCHHHHHHHCHHHHHHHHHHHHH
IGAPGVLAKTSNKGKISSYTAGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENR
CCCCCEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCC
VQLDDSIEKWLPGLVQGNGYDGNQITIRQLLNHTSGIAEYLKSKDADIMNSKKTYTAEEI
EEECHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHH
VKIGLSLPPDFSPGKDWLYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
HHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
NSPVIPGKNHARGYVKMDETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLL
CCCCCCCCCCCCCEEEECCCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KERELKEMLTTVPIEGKGVGDGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKH
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCCHHHHHHCCCCCCCE
TFAVNANSLGPVEILTQFNKMMQVEFNK
EEEEECCCCCHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MKKRNPMKLASLAVLLAGTTVFTPGFTVKAESTQNISNSSEAHDQKNRNGWKRVMQETIQ
CCCCCCHHHHHHHHHHHCCEEECCCEEEEECCCCCCCCCHHHHHHHCHHHHHHHHHHHHH
IGAPGVLAKTSNKGKISSYTAGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENR
CCCCCEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCC
VQLDDSIEKWLPGLVQGNGYDGNQITIRQLLNHTSGIAEYLKSKDADIMNSKKTYTAEEI
EEECHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHH
VKIGLSLPPDFSPGKDWLYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
HHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
NSPVIPGKNHARGYVKMDETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLL
CCCCCCCCCCCCCEEEECCCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
KERELKEMLTTVPIEGKGVGDGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKH
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCCHHHHHHCCCCCCCE
TFAVNANSLGPVEILTQFNKMMQVEFNK
EEEEECCCCCHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]