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The map label for this gene is argD [H]

Identifier: 222096495

GI number: 222096495

Start: 2773523

End: 2774740

Strand: Reverse

Name: argD [H]

Synonym: BCQ_2835

Alternate gene names: 222096495

Gene position: 2774740-2773523 (Counterclockwise)

Preceding gene: 222096497

Following gene: 222096494

Centisome position: 53.22

GC content: 35.71

Gene sequence:

>1218_bases
ATGTCGGATTGGTTTCAATTAGATAAAGAGTATATGATGTCAACGTACTGTCGTACAAAGCTTGCGATAGAAAGAGGAGA
AGGGTGTAAGCTGTATGATGTGGATGGTAAAGAGTATTTAGATTTATTTTCTGGTGTAGGCGTAAATGTATTAGGATACA
ATCATCCGAAAATTGTGCAAACGACAATGGATCAAGTTACGAAGTCGTTGCATCTACCGTTTCATTTTTTAAACCCAGTT
GCGATTGAATATGCAAAGAAATTAGTTGATTGCTCTTTAAAAAACGGAAAGGTCTTTTTTACAAACTCTGGTACGGAAGC
GACAGAAACAACGTTGAAATTAATTGATAAATATAGAGCTATTATGCATGAAGAACGTGAAGGAATTGTAGTGCTGAAGA
ATAGTTTCCACGGGCGTACGTTAGGAGCACTTCATTTTACGAGACAAGAAAGTGTATATCAAAATTTCCCTAAAACATCG
ATCCCGGTATATGAAGTTGAGCGCGAGAATATAGAGCAATTAGAAGAAACAATTATTCATGAAAATCCAATTGCAATTCT
GTTAGAACCTGTATTAGGAAGCGGGGGAATTTATCCATTATCGGGTGAATATTTACATGGTGTTCAAAATTTATGTGAGA
AATATAATGTACTACTTATCGTTGATGAGGTTCAAAGTGGTATGGGGAGAACAGGAAAACTATTCGCTTATCAAAATTTC
AATATTACACCACATATTATTCAAATTGGTAAAGGAGCAGGAGGCGGGATACCACTTGGCGGAATTATTGTAGGTGAAAA
GTTATGTGATGTATTTGCACCAGGAGATCACGGCACCACATTTGCTCATTCATCAATGGGAACGGCTTTAGGTTTAACGG
TATTAAATACATTACTTGACGATGGTTTAATGCAAGAAGCATATGAAACGTCACTATATTTGAATGACAAACTGCAAGAC
ATTCAGAAAGAAAATTCTTATTATATTCAGGAAGTGCGTCATGCGGGGATGATGTTTGGAATAAGTGTGAATGACACGAA
TGAAAATGTGAAGAAATTACAGATTGAGTTAATGAGTAAAGGAATGTTGGTCGATGTAACACAAGGGAATATTATTCGAT
TACTTCCGCCGTATATTATTACGAAAGAGGAAATTGACGCATTCACTTATGAGTTTATTTCTTGTGTTCATAACATAGCT
GCTACAGCAAGTATTTAA

Upstream 100 bases:

>100_bases
ACATTACTATTAAAATTTTAAACTTAAAAATGAATTTATATATGAATTTAAAGAAAATGAACAGAAATAAAACAGGGAGA
ATAACTAGGAGGAATGTAAC

Downstream 100 bases:

>100_bases
AAAAATATAAAAAAATATAAAAAGCTGAAGAAGCCGCTAAAATAGCGACTTCTTCAGCTTTTTAAAATAGTAAATTACTT
AACCTAGAGAGCATCTCATT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSDWFQLDKEYMMSTYCRTKLAIERGEGCKLYDVDGKEYLDLFSGVGVNVLGYNHPKIVQTTMDQVTKSLHLPFHFLNPV
AIEYAKKLVDCSLKNGKVFFTNSGTEATETTLKLIDKYRAIMHEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPKTS
IPVYEVERENIEQLEETIIHENPIAILLEPVLGSGGIYPLSGEYLHGVQNLCEKYNVLLIVDEVQSGMGRTGKLFAYQNF
NITPHIIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLDDGLMQEAYETSLYLNDKLQD
IQKENSYYIQEVRHAGMMFGISVNDTNENVKKLQIELMSKGMLVDVTQGNIIRLLPPYIITKEEIDAFTYEFISCVHNIA
ATASI

Sequences:

>Translated_405_residues
MSDWFQLDKEYMMSTYCRTKLAIERGEGCKLYDVDGKEYLDLFSGVGVNVLGYNHPKIVQTTMDQVTKSLHLPFHFLNPV
AIEYAKKLVDCSLKNGKVFFTNSGTEATETTLKLIDKYRAIMHEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPKTS
IPVYEVERENIEQLEETIIHENPIAILLEPVLGSGGIYPLSGEYLHGVQNLCEKYNVLLIVDEVQSGMGRTGKLFAYQNF
NITPHIIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLDDGLMQEAYETSLYLNDKLQD
IQKENSYYIQEVRHAGMMFGISVNDTNENVKKLQIELMSKGMLVDVTQGNIIRLLPPYIITKEEIDAFTYEFISCVHNIA
ATASI
>Mature_404_residues
SDWFQLDKEYMMSTYCRTKLAIERGEGCKLYDVDGKEYLDLFSGVGVNVLGYNHPKIVQTTMDQVTKSLHLPFHFLNPVA
IEYAKKLVDCSLKNGKVFFTNSGTEATETTLKLIDKYRAIMHEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPKTSI
PVYEVERENIEQLEETIIHENPIAILLEPVLGSGGIYPLSGEYLHGVQNLCEKYNVLLIVDEVQSGMGRTGKLFAYQNFN
ITPHIIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLDDGLMQEAYETSLYLNDKLQDI
QKENSYYIQEVRHAGMMFGISVNDTNENVKKLQIELMSKGMLVDVTQGNIIRLLPPYIITKEEIDAFTYEFISCVHNIAA
TASI

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=389, Percent_Identity=29.5629820051414, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI284507298, Length=290, Percent_Identity=29.3103448275862, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=25.5172413793103, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI37574042, Length=409, Percent_Identity=25.4278728606357, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI226442705, Length=414, Percent_Identity=24.6376811594203, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI226442709, Length=379, Percent_Identity=25.3298153034301, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI188536080, Length=423, Percent_Identity=22.6950354609929, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38679950, Length=423, Percent_Identity=22.6950354609929, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38679946, Length=423, Percent_Identity=22.6950354609929, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=32.1608040201005, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1789759, Length=392, Percent_Identity=26.7857142857143, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI145693181, Length=372, Percent_Identity=32.5268817204301, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=29.4710327455919, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=30.126582278481, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1786991, Length=387, Percent_Identity=26.6149870801034, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1786349, Length=403, Percent_Identity=26.7990074441687, Blast_Score=122, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=400, Percent_Identity=30, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI25144274, Length=279, Percent_Identity=30.4659498207885, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=27.3148148148148, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71992977, Length=416, Percent_Identity=23.3173076923077, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=444, Percent_Identity=22.0720720720721, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71981843, Length=182, Percent_Identity=26.3736263736264, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=400, Percent_Identity=32.75, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6323470, Length=410, Percent_Identity=28.2926829268293, Blast_Score=177, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6324386, Length=471, Percent_Identity=25.2653927813163, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6321456, Length=448, Percent_Identity=22.7678571428571, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357415, Length=391, Percent_Identity=31.2020460358056, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI28574759, Length=422, Percent_Identity=25.8293838862559, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=25.0585480093677, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21356575, Length=430, Percent_Identity=25.1162790697674, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281366494, Length=384, Percent_Identity=26.5625, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24667139, Length=384, Percent_Identity=26.5625, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24667143, Length=384, Percent_Identity=26.5625, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 45254; Mature: 45122

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDWFQLDKEYMMSTYCRTKLAIERGEGCKLYDVDGKEYLDLFSGVGVNVLGYNHPKIVQ
CCHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCHHHHHHHCCCCEEEEECCCCHHHH
TTMDQVTKSLHLPFHFLNPVAIEYAKKLVDCSLKNGKVFFTNSGTEATETTLKLIDKYRA
HHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
IMHEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPKTSIPVYEVERENIEQLEETIIH
HHHCCCCCEEEEECCCCCCEEEHEEEHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHC
ENPIAILLEPVLGSGGIYPLSGEYLHGVQNLCEKYNVLLIVDEVQSGMGRTGKLFAYQNF
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCEEEEEECC
NITPHIIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLD
CCCEEEEEECCCCCCCCCCCCEEHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHH
DGLMQEAYETSLYLNDKLQDIQKENSYYIQEVRHAGMMFGISVNDTNENVKKLQIELMSK
HHHHHHHHHHHEEECHHHHHHHHCCCHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCC
GMLVDVTQGNIIRLLPPYIITKEEIDAFTYEFISCVHNIAATASI
CCEEEECCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDWFQLDKEYMMSTYCRTKLAIERGEGCKLYDVDGKEYLDLFSGVGVNVLGYNHPKIVQ
CHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCHHHHHHHCCCCEEEEECCCCHHHH
TTMDQVTKSLHLPFHFLNPVAIEYAKKLVDCSLKNGKVFFTNSGTEATETTLKLIDKYRA
HHHHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHH
IMHEEREGIVVLKNSFHGRTLGALHFTRQESVYQNFPKTSIPVYEVERENIEQLEETIIH
HHHCCCCCEEEEECCCCCCEEEHEEEHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHC
ENPIAILLEPVLGSGGIYPLSGEYLHGVQNLCEKYNVLLIVDEVQSGMGRTGKLFAYQNF
CCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCEEEEEECC
NITPHIIQIGKGAGGGIPLGGIIVGEKLCDVFAPGDHGTTFAHSSMGTALGLTVLNTLLD
CCCEEEEEECCCCCCCCCCCCEEHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHH
DGLMQEAYETSLYLNDKLQDIQKENSYYIQEVRHAGMMFGISVNDTNENVKKLQIELMSK
HHHHHHHHHHHEEECHHHHHHHHCCCHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCC
GMLVDVTQGNIIRLLPPYIITKEEIDAFTYEFISCVHNIAATASI
CCEEEECCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]