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The map label for this gene is uvrD [H]

Identifier: 222096311

GI number: 222096311

Start: 2592294

End: 2594363

Strand: Reverse

Name: uvrD [H]

Synonym: BCQ_2651

Alternate gene names: 222096311

Gene position: 2594363-2592294 (Counterclockwise)

Preceding gene: 222096313

Following gene: 222096310

Centisome position: 49.76

GC content: 34.54

Gene sequence:

>2070_bases
ATGAACAACATTTTTGAAGAAGAGTTACAAAAAATGAAAGATACATTACGTACGATGGATGATCAATTAGAACAGCTTGA
AAAAATTCCAGTTTATTACGGCGATGATTTTAAAGAGCAAATTCTTGAAAGTATGAGGGAGTCTAATAGACAAAACTTAC
GTATTGGGGTACAAGAACCGTACTTTGGTAGATTAGATTTTCAAGAGGATGGCAAGGAAGAAGTTATGCCGATTTACATC
GGTAAAGTTGGTGTTTCACATAAAGATACGATGAAGCCAATTGTAATTGATTGGCGGGCACCTGTCGCAAGTATGTTTTA
TTCATTTACCGGCGGTGAAGAATTAGCGTTTTATCAATCACCGGATGGATTAGTAGAAGGTGATGTTTATTTAAAGCGAA
ATATCTCTATTCGAAAAAGAGAATTAGAACGTGTTGTTGATACATATGTAAAAGGAAATGAAGATGTCTCGCATGCCGAT
GATTTTCTTCTATATCGATTAGGTGAGAATAAAGATAATAAACTAAAGGATATTGTTTCGACGATTCAATCGGAGCAAAA
TGATATTATTCGTGCGGAAAGAAACTTGCCATTATTAATTCAAGGGGTTGCAGGGAGCGGAAAGACAACGATCGCTTTAC
ATCGCCTTGCTTTTTTAATTTATGAATATCGTGAGCAGCTAGAAGCTGAAAGAATGATTGTATTCGCTCCGAATAGTCTG
TTTTTAGACTATATTTCGAGTGTGCTTCCTGAATTAGGTGTCGGGAATATTAGTCAAACAACATTTCCGGACTGGGCATT
ACGTACGTTAGATGATTCGGTGAAACTAAAGCAGACAGATGAAAAATTGAAAGAAGCCTTTTCTATTAATCGTGATGAAA
GAAAGGTTATGCTTGGTAAATTGAAAGGTACGCTAAAATTTAAGTCCTTTATTGAAGAGCAAATGGTTCAATTCGAAAAA
GAACTAGTACCAACAAGTAATTTTGAGGCATGGGATAACGCTGTTATTCCATTGGAAGAGATAAAAAAATGGATGCAAGT
TGAGTATAAACATTATCCATTAAAGAAAAGAAGAGAACGTTTAGTTGGCCGTATGAAACGCTGGATTGAAATTGAACTGA
AAAAGTATGGAGAAACAAACGAGAAGAAATTATTAAAAAAAGAAGCGACAAAGAGATTGAACAGTTATATGAAGTTTTGG
CCGAAAATGAGCTCACTTTCAATATATAGTTCAATATTGAAAAGTAAAGAAATACTCGAAGTATTACCTGAAGAACTTGT
GAAAGAAACCGAAAAGAGTTGTCGTAAAAAAGAAGTGTATGTAGAAGATTTACCCGCTTTAATATACATACATCATCGCA
TCACAGGTATTGAAATTGGACAAAAGTTTCATCACGTCGTTATTGATGAAGCGCAAGATTTCTCACCATTCCAAGTTTAT
GTATTAAAAGAAATTACATTAGGTAATTCTTTCACTATATTAGGTGATTTATCTCAAGCGATTTATGATTACCAAGGGAT
TGAAGATTGGAGTGCTTTTAAGGAAGTATTCCAAGAAACAGGCTATTATGAACTGACGAGAAGCTATCGTTCTACAAAAG
AAATTATTGAATTTGCGAACGAAATAATTAAAAATGCCGAGATTCCAGTAGGGCTTGCGACACCAGTTTTTCGTAGTGGT
GAAGAGGTCAAAGTAATTCAAGCAGAAGATCAATTTAATGAGATTATGAAGACGTTAAAACATTTACAAAATGATGATGT
GAAAACAATTGCGGTAATAGGAAGAACAGACGATGAATGTCGCGATATATATGAGAAATTAACAAAGGCAGGAGTAGCTG
TAAACGTCATTGAAGCAGATCAAAGTAAATATGAAGGTGGTATTTCAGTTGTACCTGTATACTTGGCAAAAGGGCTAGAA
TTTGACGCTGTTCTACTAATTGATGTTGATGAAGAACATTACAAAAATACAAAACACGATGCAAAGTTACTATATGTCGG
ATGTACGAGATCACTTCATGATTTATGGATTTTCCATAGTGGGGAAGCATCTCCGTTAATTAAGAAATAA

Upstream 100 bases:

>100_bases
TTTTCAGAAAAAACAAACTAAGTCCTTGACTTTATAATTGGATTTTTAATACAATTATATTTCGACTGAAAAATTAGAAC
GGACAGGAGGGAATCATCAA

Downstream 100 bases:

>100_bases
AAATTCAAGAGGCTTTTCTAATAATGAATAGAAGAGCCTCTTGTTTTTATAAAGAAATAGGAGAAATGATAATGATTACA
AAAGTCATAACAAAGAGAAA

Product: uvrd/rep helicase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MNNIFEEELQKMKDTLRTMDDQLEQLEKIPVYYGDDFKEQILESMRESNRQNLRIGVQEPYFGRLDFQEDGKEEVMPIYI
GKVGVSHKDTMKPIVIDWRAPVASMFYSFTGGEELAFYQSPDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHAD
DFLLYRLGENKDNKLKDIVSTIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
FLDYISSVLPELGVGNISQTTFPDWALRTLDDSVKLKQTDEKLKEAFSINRDERKVMLGKLKGTLKFKSFIEEQMVQFEK
ELVPTSNFEAWDNAVIPLEEIKKWMQVEYKHYPLKKRRERLVGRMKRWIEIELKKYGETNEKKLLKKEATKRLNSYMKFW
PKMSSLSIYSSILKSKEILEVLPEELVKETEKSCRKKEVYVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
VLKEITLGNSFTILGDLSQAIYDYQGIEDWSAFKEVFQETGYYELTRSYRSTKEIIEFANEIIKNAEIPVGLATPVFRSG
EEVKVIQAEDQFNEIMKTLKHLQNDDVKTIAVIGRTDDECRDIYEKLTKAGVAVNVIEADQSKYEGGISVVPVYLAKGLE
FDAVLLIDVDEEHYKNTKHDAKLLYVGCTRSLHDLWIFHSGEASPLIKK

Sequences:

>Translated_689_residues
MNNIFEEELQKMKDTLRTMDDQLEQLEKIPVYYGDDFKEQILESMRESNRQNLRIGVQEPYFGRLDFQEDGKEEVMPIYI
GKVGVSHKDTMKPIVIDWRAPVASMFYSFTGGEELAFYQSPDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHAD
DFLLYRLGENKDNKLKDIVSTIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
FLDYISSVLPELGVGNISQTTFPDWALRTLDDSVKLKQTDEKLKEAFSINRDERKVMLGKLKGTLKFKSFIEEQMVQFEK
ELVPTSNFEAWDNAVIPLEEIKKWMQVEYKHYPLKKRRERLVGRMKRWIEIELKKYGETNEKKLLKKEATKRLNSYMKFW
PKMSSLSIYSSILKSKEILEVLPEELVKETEKSCRKKEVYVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
VLKEITLGNSFTILGDLSQAIYDYQGIEDWSAFKEVFQETGYYELTRSYRSTKEIIEFANEIIKNAEIPVGLATPVFRSG
EEVKVIQAEDQFNEIMKTLKHLQNDDVKTIAVIGRTDDECRDIYEKLTKAGVAVNVIEADQSKYEGGISVVPVYLAKGLE
FDAVLLIDVDEEHYKNTKHDAKLLYVGCTRSLHDLWIFHSGEASPLIKK
>Mature_689_residues
MNNIFEEELQKMKDTLRTMDDQLEQLEKIPVYYGDDFKEQILESMRESNRQNLRIGVQEPYFGRLDFQEDGKEEVMPIYI
GKVGVSHKDTMKPIVIDWRAPVASMFYSFTGGEELAFYQSPDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHAD
DFLLYRLGENKDNKLKDIVSTIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
FLDYISSVLPELGVGNISQTTFPDWALRTLDDSVKLKQTDEKLKEAFSINRDERKVMLGKLKGTLKFKSFIEEQMVQFEK
ELVPTSNFEAWDNAVIPLEEIKKWMQVEYKHYPLKKRRERLVGRMKRWIEIELKKYGETNEKKLLKKEATKRLNSYMKFW
PKMSSLSIYSSILKSKEILEVLPEELVKETEKSCRKKEVYVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
VLKEITLGNSFTILGDLSQAIYDYQGIEDWSAFKEVFQETGYYELTRSYRSTKEIIEFANEIIKNAEIPVGLATPVFRSG
EEVKVIQAEDQFNEIMKTLKHLQNDDVKTIAVIGRTDDECRDIYEKLTKAGVAVNVIEADQSKYEGGISVVPVYLAKGLE
FDAVLLIDVDEEHYKNTKHDAKLLYVGCTRSLHDLWIFHSGEASPLIKK

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787196, Length=518, Percent_Identity=23.3590733590734, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 79954; Mature: 79954

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIFEEELQKMKDTLRTMDDQLEQLEKIPVYYGDDFKEQILESMRESNRQNLRIGVQEP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHCCCCCEEEECCCC
YFGRLDFQEDGKEEVMPIYIGKVGVSHKDTMKPIVIDWRAPVASMFYSFTGGEELAFYQS
CCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCCHHHHHHHHCCCCCEEEEEEC
PDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHADDFLLYRLGENKDNKLKDIVS
CCCCEECCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHCEEEEEECCCCCHHHHHHHH
TIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
HHHCCCCCCEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHH
FLDYISSVLPELGVGNISQTTFPDWALRTLDDSVKLKQTDEKLKEAFSINRDERKVMLGK
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LKGTLKFKSFIEEQMVQFEKELVPTSNFEAWDNAVIPLEEIKKWMQVEYKHYPLKKRRER
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
LVGRMKRWIEIELKKYGETNEKKLLKKEATKRLNSYMKFWPKMSSLSIYSSILKSKEILE
HHHHHHHHHEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VLPEELVKETEKSCRKKEVYVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
HHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEHHCCHHHHHHHHHHHHHCCCCCCCCEEEE
VLKEITLGNSFTILGDLSQAIYDYQGIEDWSAFKEVFQETGYYELTRSYRSTKEIIEFAN
EEEEEECCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EIIKNAEIPVGLATPVFRSGEEVKVIQAEDQFNEIMKTLKHLQNDDVKTIAVIGRTDDEC
HHHHCCCCCCCCCCHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHH
RDIYEKLTKAGVAVNVIEADQSKYEGGISVVPVYLAKGLEFDAVLLIDVDEEHYKNTKHD
HHHHHHHHHCCCEEEEEECCCHHHCCCCEEEHHHHHCCCCCCEEEEEECCHHHCCCCCCC
AKLLYVGCTRSLHDLWIFHSGEASPLIKK
CEEEEEECCCCHHHEEEEECCCCCCCCCC
>Mature Secondary Structure
MNNIFEEELQKMKDTLRTMDDQLEQLEKIPVYYGDDFKEQILESMRESNRQNLRIGVQEP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHCCCCCEEEECCCC
YFGRLDFQEDGKEEVMPIYIGKVGVSHKDTMKPIVIDWRAPVASMFYSFTGGEELAFYQS
CCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEECCCHHHHHHHHCCCCCEEEEEEC
PDGLVEGDVYLKRNISIRKRELERVVDTYVKGNEDVSHADDFLLYRLGENKDNKLKDIVS
CCCCEECCEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHCEEEEEECCCCCHHHHHHHH
TIQSEQNDIIRAERNLPLLIQGVAGSGKTTIALHRLAFLIYEYREQLEAERMIVFAPNSL
HHHCCCCCCEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHH
FLDYISSVLPELGVGNISQTTFPDWALRTLDDSVKLKQTDEKLKEAFSINRDERKVMLGK
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LKGTLKFKSFIEEQMVQFEKELVPTSNFEAWDNAVIPLEEIKKWMQVEYKHYPLKKRRER
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHH
LVGRMKRWIEIELKKYGETNEKKLLKKEATKRLNSYMKFWPKMSSLSIYSSILKSKEILE
HHHHHHHHHEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VLPEELVKETEKSCRKKEVYVEDLPALIYIHHRITGIEIGQKFHHVVIDEAQDFSPFQVY
HHHHHHHHHHHHHHHHHCCHHHCCCEEEEEEHHCCHHHHHHHHHHHHHCCCCCCCCEEEE
VLKEITLGNSFTILGDLSQAIYDYQGIEDWSAFKEVFQETGYYELTRSYRSTKEIIEFAN
EEEEEECCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
EIIKNAEIPVGLATPVFRSGEEVKVIQAEDQFNEIMKTLKHLQNDDVKTIAVIGRTDDEC
HHHHCCCCCCCCCCHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHH
RDIYEKLTKAGVAVNVIEADQSKYEGGISVVPVYLAKGLEFDAVLLIDVDEEHYKNTKHD
HHHHHHHHHCCCEEEEEECCCHHHCCCCEEEHHHHHCCCCCCEEEEEECCHHHCCCCCCC
AKLLYVGCTRSLHDLWIFHSGEASPLIKK
CEEEEEECCCCHHHEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]