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The map label for this gene is fes [H]

Identifier: 222096212

GI number: 222096212

Start: 2512436

End: 2513632

Strand: Reverse

Name: fes [H]

Synonym: BCQ_2552

Alternate gene names: 222096212

Gene position: 2513632-2512436 (Counterclockwise)

Preceding gene: 222096213

Following gene: 222096211

Centisome position: 48.21

GC content: 33.0

Gene sequence:

>1197_bases
GTGACTACAATAATCAGTCCTAAGTTAGAGAAGCTTAAAAATCAATTAAAGAATGGAAACGAAAAAGCTCTTTATACTTT
TTTGGATGAAATCAAGTCAAATCATACACCACTAGTAGAACAATGTCCTATAGATAATCAGTATAAACTTATAACGTATA
TATGGTTAGGTGATCAAAATACTGAAAATGTTTATGTAGTCGGTAGTTTTCCTGGTTGGGATCTGTCTGTAAATCAATTA
CAACGATTGTTACAGACAGATATTTGGTATGTAACGTTTAAGACGAATAAGAGTTTTATTTCAACGTACTATTTTTCAGT
AAACGATGTTTTCGAAAATGATTGGATAAAGCGTAGTGAACAGTACGAAATAGACCAATTTAATCGAAATACATTTGGAG
AAGGTACCAATAAAGCGTCTGTGTTAAACATAGGAATGGAGGTGCAATATAGCAGTCGTTTTCCTTCAAATGATTATCCA
TCCGGAAAGATTGAAACATATTCTTTTTATAGTTCGATTTTAAATAACACACGTAAAATTCATATTTATACGCCTCATGA
TTATTCTCACACTTCACATCTTCAAGAACTTCTCATTGTATTTGATGGGAATTCATTCATTAATGACCTTTCAATCACAA
AAACACTTAATTATTTAATTTACGAAAAAGAAATCCCATCGTGTATTGCTGTTGCTATAGATCCTGTTGATCGATTAGAA
GAGCTAACTTATAACGATAAAATGAACGCATTTTTAACGAAGGAATTACTTCTGTGGATTCAGGCTAAGTATCGTGTGCA
TAAAGAAGCGAAACATACAACAATTGCAGGTTTCAGTCTTGGTGGCCTAGCAGCTTTTTATGCAGCACTTCAAAATCCGC
ATATTTTCGGGAATGTGTTGTCAATGTCTGGATCTGTACATTGGAAAAAAGATGGTTATGAAAATCAAATTCCTTGGATT
GAAAATCAAATTTCATCAATAGATTCTAATACGACTCATCTCTATTCTTACATAGCAGTAGGTGAACTTGAAAACGAATC
TCTTTTAACGGCCAATAGGCGCCTATATAAAGCTTTAAAAGAAAATAGATACCAAACCACTTATGAAGAGTTCCAAGGCG
GACATGACGGTATTTGGTGGCGAGAAAATTTGTTTGACGGGTTGAAAGCTTTAAAACTTACAAAAAACACACTATAA

Upstream 100 bases:

>100_bases
TCTAATCAATAACTTCTCTAAACACATAACTTACGACTGCTTTTATATAGGGATTCTAATGAAAAAACTACATATAGAAT
ACTACAAAGGAGGAAGAGAG

Downstream 100 bases:

>100_bases
AATAAAAAGGAGAGAGAATCTATGAATCAAGAAGAACTAGATAAGAAACTAAAAAAGCAAGAGATTTTAGTAAAAGATGA
GAAAGTTTGGTCCTATACAT

Product: hypothetical protein

Products: Fe [C]

Alternate protein names: Ferric enterobactin esterase [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTTIISPKLEKLKNQLKNGNEKALYTFLDEIKSNHTPLVEQCPIDNQYKLITYIWLGDQNTENVYVVGSFPGWDLSVNQL
QRLLQTDIWYVTFKTNKSFISTYYFSVNDVFENDWIKRSEQYEIDQFNRNTFGEGTNKASVLNIGMEVQYSSRFPSNDYP
SGKIETYSFYSSILNNTRKIHIYTPHDYSHTSHLQELLIVFDGNSFINDLSITKTLNYLIYEKEIPSCIAVAIDPVDRLE
ELTYNDKMNAFLTKELLLWIQAKYRVHKEAKHTTIAGFSLGGLAAFYAALQNPHIFGNVLSMSGSVHWKKDGYENQIPWI
ENQISSIDSNTTHLYSYIAVGELENESLLTANRRLYKALKENRYQTTYEEFQGGHDGIWWRENLFDGLKALKLTKNTL

Sequences:

>Translated_398_residues
MTTIISPKLEKLKNQLKNGNEKALYTFLDEIKSNHTPLVEQCPIDNQYKLITYIWLGDQNTENVYVVGSFPGWDLSVNQL
QRLLQTDIWYVTFKTNKSFISTYYFSVNDVFENDWIKRSEQYEIDQFNRNTFGEGTNKASVLNIGMEVQYSSRFPSNDYP
SGKIETYSFYSSILNNTRKIHIYTPHDYSHTSHLQELLIVFDGNSFINDLSITKTLNYLIYEKEIPSCIAVAIDPVDRLE
ELTYNDKMNAFLTKELLLWIQAKYRVHKEAKHTTIAGFSLGGLAAFYAALQNPHIFGNVLSMSGSVHWKKDGYENQIPWI
ENQISSIDSNTTHLYSYIAVGELENESLLTANRRLYKALKENRYQTTYEEFQGGHDGIWWRENLFDGLKALKLTKNTL
>Mature_397_residues
TTIISPKLEKLKNQLKNGNEKALYTFLDEIKSNHTPLVEQCPIDNQYKLITYIWLGDQNTENVYVVGSFPGWDLSVNQLQ
RLLQTDIWYVTFKTNKSFISTYYFSVNDVFENDWIKRSEQYEIDQFNRNTFGEGTNKASVLNIGMEVQYSSRFPSNDYPS
GKIETYSFYSSILNNTRKIHIYTPHDYSHTSHLQELLIVFDGNSFINDLSITKTLNYLIYEKEIPSCIAVAIDPVDRLEE
LTYNDKMNAFLTKELLLWIQAKYRVHKEAKHTTIAGFSLGGLAAFYAALQNPHIFGNVLSMSGSVHWKKDGYENQIPWIE
NQISSIDSNTTHLYSYIAVGELENESLLTANRRLYKALKENRYQTTYEEFQGGHDGIWWRENLFDGLKALKLTKNTL

Specific function: Upon internalization, ferric enterobactin is processed via an exquisitely specific pathway that is dependent on FES activity, making iron available for metabolic use [H]

COG id: COG2382

COG function: function code P; Enterochelin esterase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fes family [H]

Homologues:

Organism=Escherichia coli, GI1786799, Length=366, Percent_Identity=25.9562841530055, Blast_Score=114, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021764
- InterPro:   IPR000801
- InterPro:   IPR014756 [H]

Pfam domain/function: PF11806 DUF3327; PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 46181; Mature: 46050

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIISPKLEKLKNQLKNGNEKALYTFLDEIKSNHTPLVEQCPIDNQYKLITYIWLGDQN
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEEEEECCCC
TENVYVVGSFPGWDLSVNQLQRLLQTDIWYVTFKTNKSFISTYYFSVNDVFENDWIKRSE
CCCEEEEECCCCCCCCHHHHHHHHHCCEEEEEEECCCCEEEEEEEEEHHHHHCHHHCCCC
QYEIDQFNRNTFGEGTNKASVLNIGMEVQYSSRFPSNDYPSGKIETYSFYSSILNNTRKI
CCCHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHCCCEEE
HIYTPHDYSHTSHLQELLIVFDGNSFINDLSITKTLNYLIYEKEIPSCIAVAIDPVDRLE
EEECCCCCCHHHHHHEEEEEECCCCHHHHHHHHHHHHHEEECCCCCCEEEEEECCHHHHH
ELTYNDKMNAFLTKELLLWIQAKYRVHKEAKHTTIAGFSLGGLAAFYAALQNPHIFGNVL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCEEEEHE
SMSGSVHWKKDGYENQIPWIENQISSIDSNTTHLYSYIAVGELENESLLTANRRLYKALK
ECCCCEEECCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHH
ENRYQTTYEEFQGGHDGIWWRENLFDGLKALKLTKNTL
HCCCCCCHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTIISPKLEKLKNQLKNGNEKALYTFLDEIKSNHTPLVEQCPIDNQYKLITYIWLGDQN
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCEEEEEEEEECCCC
TENVYVVGSFPGWDLSVNQLQRLLQTDIWYVTFKTNKSFISTYYFSVNDVFENDWIKRSE
CCCEEEEECCCCCCCCHHHHHHHHHCCEEEEEEECCCCEEEEEEEEEHHHHHCHHHCCCC
QYEIDQFNRNTFGEGTNKASVLNIGMEVQYSSRFPSNDYPSGKIETYSFYSSILNNTRKI
CCCHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHCCCEEE
HIYTPHDYSHTSHLQELLIVFDGNSFINDLSITKTLNYLIYEKEIPSCIAVAIDPVDRLE
EEECCCCCCHHHHHHEEEEEECCCCHHHHHHHHHHHHHEEECCCCCCEEEEEECCHHHHH
ELTYNDKMNAFLTKELLLWIQAKYRVHKEAKHTTIAGFSLGGLAAFYAALQNPHIFGNVL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCEEEEHE
SMSGSVHWKKDGYENQIPWIENQISSIDSNTTHLYSYIAVGELENESLLTANRRLYKALK
ECCCCEEECCCCCCCCCCCHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHH
ENRYQTTYEEFQGGHDGIWWRENLFDGLKALKLTKNTL
HCCCCCCHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrienterobactin [C]

Specific reaction: ferrienterobactin = Fe [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2974033; 9278503; 8905232 [H]