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The map label for this gene is gntR [H]

Identifier: 222096192

GI number: 222096192

Start: 2495150

End: 2496583

Strand: Reverse

Name: gntR [H]

Synonym: BCQ_2532

Alternate gene names: 222096192

Gene position: 2496583-2495150 (Counterclockwise)

Preceding gene: 222096210

Following gene: 222096190

Centisome position: 47.88

GC content: 33.96

Gene sequence:

>1434_bases
ATGACCACTAGTAAAAAACTACCTAAGTATCAGCAGATAGTAGACTATATGAAAGAAAAAATTGAAAATGGAGAATGGCC
TATAGGAAGTAAGATTCCTAGTCAACGGCAGTTAGCGAAATTATTTCAAGTAAATCGTAGTACTGTAATAACTGCACTAG
ATGAACTTATGGCTGATGGATTGATTCAAGGGAAAATTGGAGCAGGAACAATTGTAACGAATAATACATGGTCATTATTA
GCAACAAATCCACCACCTGATTGGAGTGAATATGTAAAGGCTGGTATTCATAAACCAAGCAAGTTAATGGTACGAGAAAT
AAATGAAGCAGAAGCAAATAACAAACTTATCCATCTTAGTAAAGGCGAACTTTCTCCTCATCTTTTTCCATTAGAAACGA
TGCAGTCCATTATGAAGAAAGTAAGTGAGGAATTAGACTATTTTGGATATGAGGAACAAAAAGGGTTTTATCCGTTACGT
GAAGCAATAAGTAAATACGTAAAATCATTTGGAATACATGCATCACCGGGTTCCATATTAATCGTCTCGGGTGCATTACA
AGCATTGCAATTAATATCAATTGGTCTTTTACATAGAGAGTCTACCGTTTTACTTGAACAACCTTCTTACTTATATTCAC
TTCATGTATTTCAATCAGCAAATATAAATCTATCTGGTATATCTATGGATCCTCACGGTATATTACCTAACGAGTTATTA
AAACGAATTAAATACAGTCAGAAGAAAAACATCTTATATTCAATTCCTTGTTTTCAAAATCCAACAGGTATATTAATGTC
TAAAGAGCGGAGAAAAGAAATATTAAAAATATGTGAAAAGGAACAGTTACCTATTATTGAAGATGATATTTACCGCGAGT
TATGGATTGATGCACCGCCCCCAGATCCTTTAAAATCGAGAGATAAACATGGACATATATTATATATTGGTAGTCTCTCT
AAGACGCTTACCCCAGGACTTAGAATTGGATGGGTTATCGGTCCAGAACCCGTTATTGATAGATTATCAGATATAAAAAT
GCAAACAGATTATGGATCGAGTTCATTATCTCAAAGAGTTGCTGCTGAATGGATAAATAAAGGATTTTATGAGGAACATG
TTGCAAACGTAAGAATTAAACTAAAAGAACGAAGACAAATAATGATACGAGCTTTACATAAGTATTGTGCAGATATTGCC
ACCTGGGATATTCCTAGTGGTGGATTTTTTATATGGCTAAAGGTAGTACCTAGCATTCCGATGAAGAAATTATTTTCAAA
GGCACTATCAAAAGGGATTCTATTAAACCCGGGACGTATCTATGAAGAGGAATCAGATCGATACATTCGTTTATCATATG
GATATGCTTCTCCAGAGCAAATGACTAACGGTATTAAATTGTTAAGCGAATTAATTCGTAAGTTAATGACATAA

Upstream 100 bases:

>100_bases
CTTCCCATCATATTTAATAGTTGATACAATGTCTTCAACCAGTTTTTTATCGTAAAAACCAACCACTTGGCATTTTTCAA
GTGAGCGAAGGAGTTTTTTG

Downstream 100 bases:

>100_bases
TAAAAACTCCTCTTTTTCCATAGAGGAGTTTTTGTGTATTTTATTTACCACAACCGCATTTCCTGCCCCAACACAATAAG
TCCTTCATAAGGATCCCCGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MTTSKKLPKYQQIVDYMKEKIENGEWPIGSKIPSQRQLAKLFQVNRSTVITALDELMADGLIQGKIGAGTIVTNNTWSLL
ATNPPPDWSEYVKAGIHKPSKLMVREINEAEANNKLIHLSKGELSPHLFPLETMQSIMKKVSEELDYFGYEEQKGFYPLR
EAISKYVKSFGIHASPGSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHGILPNELL
KRIKYSQKKNILYSIPCFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWIDAPPPDPLKSRDKHGHILYIGSLS
KTLTPGLRIGWVIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALHKYCADIA
TWDIPSGGFFIWLKVVPSIPMKKLFSKALSKGILLNPGRIYEEESDRYIRLSYGYASPEQMTNGIKLLSELIRKLMT

Sequences:

>Translated_477_residues
MTTSKKLPKYQQIVDYMKEKIENGEWPIGSKIPSQRQLAKLFQVNRSTVITALDELMADGLIQGKIGAGTIVTNNTWSLL
ATNPPPDWSEYVKAGIHKPSKLMVREINEAEANNKLIHLSKGELSPHLFPLETMQSIMKKVSEELDYFGYEEQKGFYPLR
EAISKYVKSFGIHASPGSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHGILPNELL
KRIKYSQKKNILYSIPCFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWIDAPPPDPLKSRDKHGHILYIGSLS
KTLTPGLRIGWVIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALHKYCADIA
TWDIPSGGFFIWLKVVPSIPMKKLFSKALSKGILLNPGRIYEEESDRYIRLSYGYASPEQMTNGIKLLSELIRKLMT
>Mature_476_residues
TTSKKLPKYQQIVDYMKEKIENGEWPIGSKIPSQRQLAKLFQVNRSTVITALDELMADGLIQGKIGAGTIVTNNTWSLLA
TNPPPDWSEYVKAGIHKPSKLMVREINEAEANNKLIHLSKGELSPHLFPLETMQSIMKKVSEELDYFGYEEQKGFYPLRE
AISKYVKSFGIHASPGSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHGILPNELLK
RIKYSQKKNILYSIPCFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWIDAPPPDPLKSRDKHGHILYIGSLSK
TLTPGLRIGWVIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALHKYCADIAT
WDIPSGGFFIWLKVVPSIPMKKLFSKALSKGILLNPGRIYEEESDRYIRLSYGYASPEQMTNGIKLLSELIRKLMT

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=394, Percent_Identity=28.9340101522843, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI33469970, Length=394, Percent_Identity=28.9340101522843, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI4507369, Length=258, Percent_Identity=27.1317829457364, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787710, Length=473, Percent_Identity=24.5243128964059, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1790797, Length=485, Percent_Identity=26.1855670103093, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788722, Length=326, Percent_Identity=23.9263803680982, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321236, Length=360, Percent_Identity=24.4444444444444, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6321000, Length=271, Percent_Identity=26.5682656826568, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321929, Length=397, Percent_Identity=20.1511335012594, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356535, Length=355, Percent_Identity=23.6619718309859, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI18859735, Length=209, Percent_Identity=25.8373205741627, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54191; Mature: 54060

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSKKLPKYQQIVDYMKEKIENGEWPIGSKIPSQRQLAKLFQVNRSTVITALDELMADG
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCC
LIQGKIGAGTIVTNNTWSLLATNPPPDWSEYVKAGIHKPSKLMVREINEAEANNKLIHLS
CEECCCCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEE
KGELSPHLFPLETMQSIMKKVSEELDYFGYEEQKGFYPLREAISKYVKSFGIHASPGSIL
CCCCCCCEECHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCEE
IVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHGILPNELL
EEHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCEEEEEECCCCCCCCHHHHH
KRIKYSQKKNILYSIPCFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWIDAPP
HHHHHHHHCCEEEECCCCCCCCCCEECHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
PDPLKSRDKHGHILYIGSLSKTLTPGLRIGWVIGPEPVIDRLSDIKMQTDYGSSSLSQRV
CCCCCCCCCCCCEEEEECCHHHCCCCCEEEEEECCHHHHHHHHHCEEECCCCCHHHHHHH
AAEWINKGFYEEHVANVRIKLKERRQIMIRALHKYCADIATWDIPSGGFFIWLKVVPSIP
HHHHHHCCHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
MKKLFSKALSKGILLNPGRIYEEESDRYIRLSYGYASPEQMTNGIKLLSELIRKLMT
HHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTSKKLPKYQQIVDYMKEKIENGEWPIGSKIPSQRQLAKLFQVNRSTVITALDELMADG
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCC
LIQGKIGAGTIVTNNTWSLLATNPPPDWSEYVKAGIHKPSKLMVREINEAEANNKLIHLS
CEECCCCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEE
KGELSPHLFPLETMQSIMKKVSEELDYFGYEEQKGFYPLREAISKYVKSFGIHASPGSIL
CCCCCCCEECHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCEE
IVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHGILPNELL
EEHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCEEEEEECCCCCCCCHHHHH
KRIKYSQKKNILYSIPCFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWIDAPP
HHHHHHHHCCEEEECCCCCCCCCCEECHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
PDPLKSRDKHGHILYIGSLSKTLTPGLRIGWVIGPEPVIDRLSDIKMQTDYGSSSLSQRV
CCCCCCCCCCCCEEEEECCHHHCCCCCEEEEEECCHHHHHHHHHCEEECCCCCHHHHHHH
AAEWINKGFYEEHVANVRIKLKERRQIMIRALHKYCADIATWDIPSGGFFIWLKVVPSIP
HHHHHHCCHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
MKKLFSKALSKGILLNPGRIYEEESDRYIRLSYGYASPEQMTNGIKLLSELIRKLMT
HHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]