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The map label for this gene is kinB [H]

Identifier: 222096169

GI number: 222096169

Start: 2472823

End: 2474091

Strand: Reverse

Name: kinB [H]

Synonym: BCQ_2509

Alternate gene names: 222096169

Gene position: 2474091-2472823 (Counterclockwise)

Preceding gene: 222096170

Following gene: 222096164

Centisome position: 47.45

GC content: 29.31

Gene sequence:

>1269_bases
ATGAACTTTGTGTATATCAATCAACACGTGTTAAATAACCTTCTATACATTTTAAGTAGCATATTTATTTTTTATTTTAT
ATATGATAGCGGGCGCAATTTGAAGAAATATAAAAAACTACTTATTATACTTTGTACGAGTATCCCTCTTATTTTATGTA
TGCGCTATCCTATCTATATGGATGAAAATTGTATTCATGATTTAAGACAAATACCGGTTATAGTAGGTACGCTTTATGGT
GGCTTCCCTGTCGGTATAACATTGTTTGCTATTTTATTAATTACAAGATTTTCATTTTATGGATTTAGTATATTAACAAT
AGTAGTGTATGGAACAATGTTTATCATTACAGCATTCGCATCCGCAAAATTTAATACGTATAATAGAAAAATTAAAGTAG
CTTATGCAATGTTTTTAACATTTTTCTTAGCAATATTTACAACTGTAATTGTATTAACTTTATCAGATTTTGAAGTGAAT
AATTTGTACATCATTTATTTCATAATATTACCAACCGTTTTAATGTTGTTTGTAGTTTATTTTAATGAAGTTTTAAAAGA
TGCAGTATGCATGCGATCGAAGTTAATTAAAATGGAAAAAATGGAGATTGTTAGCCAACTCGCTGCTAGTATATCGCACG
AAGTAAGAAATCCCTTAACTGTTGTAAAAGGATTTACACAACTTTTAAAAACACCAAATTTAACTCCAGAATCAAGAGAC
GAGTATATTAAGCATATACTGGAAGAATTACATCATGCCCAAGGGATTATTGATGATTATTTAACGTTTGCTAAACCTGC
TTCAGAAAAGTTAGATGAGATTTCAGTAGAACAAGAATTAAATCGAGTTATTAATATGATCTTACCTTTATGTAATATGA
ATACAATACATATTACAAAAGATTTCTCTACGGCAACAATAGTTGGTAATAAACAGCACTTTCAGCAATGTTTTTTAAAC
TTATTAAAAAATGGTATTGAAGCAATGCCTAATGGCGGTACTTTACATATCTCCTCTTCTATTAGTAATAATAAAGTTAT
CATACGAATTGAAGATAGCGGAATTGGTATGTCACAAGAGCAAATAAATCGATTTGGCGAACCGTATTTTAGTACAAAAA
CGAAAGGTACAGGTTTAGGTACAATGGTTGCTGTGAAAATCATTGAAACGATGCACGGTAGTTTAAAAATCCGAAGCGTT
ATGAATAAAGGAACTACTTTGACAATTACATTCCCGAAATGTAATAAAAACGCATCTAACAACAAATAA

Upstream 100 bases:

>100_bases
AAAAAGATATAAATCTATATTATTCAAACAAATATATAGTTTATACTATTATCATGATAATATATATGAAAAGGAAATTA
AAAATAACGAGGCAAATATT

Downstream 100 bases:

>100_bases
AAAAGGAGCATAATCGCTCCTTTTTTATTTGTTTCGATACAGAAGTATCTTCTATGTTTTTTTAGTTTACATTTGTGGAG
ACTAATTAAAAATTAGTACC

Product: sporulation kinase b

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MNFVYINQHVLNNLLYILSSIFIFYFIYDSGRNLKKYKKLLIILCTSIPLILCMRYPIYMDENCIHDLRQIPVIVGTLYG
GFPVGITLFAILLITRFSFYGFSILTIVVYGTMFIITAFASAKFNTYNRKIKVAYAMFLTFFLAIFTTVIVLTLSDFEVN
NLYIIYFIILPTVLMLFVVYFNEVLKDAVCMRSKLIKMEKMEIVSQLAASISHEVRNPLTVVKGFTQLLKTPNLTPESRD
EYIKHILEELHHAQGIIDDYLTFAKPASEKLDEISVEQELNRVINMILPLCNMNTIHITKDFSTATIVGNKQHFQQCFLN
LLKNGIEAMPNGGTLHISSSISNNKVIIRIEDSGIGMSQEQINRFGEPYFSTKTKGTGLGTMVAVKIIETMHGSLKIRSV
MNKGTTLTITFPKCNKNASNNK

Sequences:

>Translated_422_residues
MNFVYINQHVLNNLLYILSSIFIFYFIYDSGRNLKKYKKLLIILCTSIPLILCMRYPIYMDENCIHDLRQIPVIVGTLYG
GFPVGITLFAILLITRFSFYGFSILTIVVYGTMFIITAFASAKFNTYNRKIKVAYAMFLTFFLAIFTTVIVLTLSDFEVN
NLYIIYFIILPTVLMLFVVYFNEVLKDAVCMRSKLIKMEKMEIVSQLAASISHEVRNPLTVVKGFTQLLKTPNLTPESRD
EYIKHILEELHHAQGIIDDYLTFAKPASEKLDEISVEQELNRVINMILPLCNMNTIHITKDFSTATIVGNKQHFQQCFLN
LLKNGIEAMPNGGTLHISSSISNNKVIIRIEDSGIGMSQEQINRFGEPYFSTKTKGTGLGTMVAVKIIETMHGSLKIRSV
MNKGTTLTITFPKCNKNASNNK
>Mature_422_residues
MNFVYINQHVLNNLLYILSSIFIFYFIYDSGRNLKKYKKLLIILCTSIPLILCMRYPIYMDENCIHDLRQIPVIVGTLYG
GFPVGITLFAILLITRFSFYGFSILTIVVYGTMFIITAFASAKFNTYNRKIKVAYAMFLTFFLAIFTTVIVLTLSDFEVN
NLYIIYFIILPTVLMLFVVYFNEVLKDAVCMRSKLIKMEKMEIVSQLAASISHEVRNPLTVVKGFTQLLKTPNLTPESRD
EYIKHILEELHHAQGIIDDYLTFAKPASEKLDEISVEQELNRVINMILPLCNMNTIHITKDFSTATIVGNKQHFQQCFLN
LLKNGIEAMPNGGTLHISSSISNNKVIIRIEDSGIGMSQEQINRFGEPYFSTKTKGTGLGTMVAVKIIETMHGSLKIRSV
MNKGTTLTITFPKCNKNASNNK

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the kinB activity [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=278, Percent_Identity=26.2589928057554, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=27.6315789473684, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=30.1724137931034, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693157, Length=263, Percent_Identity=28.8973384030418, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788713, Length=232, Percent_Identity=28.0172413793103, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=23.4513274336283, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790861, Length=232, Percent_Identity=22.4137931034483, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790300, Length=226, Percent_Identity=23.8938053097345, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=22.4409448818898, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47992; Mature: 47992

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFVYINQHVLNNLLYILSSIFIFYFIYDSGRNLKKYKKLLIILCTSIPLILCMRYPIYM
CCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
DENCIHDLRQIPVIVGTLYGGFPVGITLFAILLITRFSFYGFSILTIVVYGTMFIITAFA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAKFNTYNRKIKVAYAMFLTFFLAIFTTVIVLTLSDFEVNNLYIIYFIILPTVLMLFVVY
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEHHHHHHHHHHHHHHHH
FNEVLKDAVCMRSKLIKMEKMEIVSQLAASISHEVRNPLTVVKGFTQLLKTPNLTPESRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHH
EYIKHILEELHHAQGIIDDYLTFAKPASEKLDEISVEQELNRVINMILPLCNMNTIHITK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DFSTATIVGNKQHFQQCFLNLLKNGIEAMPNGGTLHISSSISNNKVIIRIEDSGIGMSQE
CCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCHH
QINRFGEPYFSTKTKGTGLGTMVAVKIIETMHGSLKIRSVMNKGTTLTITFPKCNKNASN
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCCC
NK
CC
>Mature Secondary Structure
MNFVYINQHVLNNLLYILSSIFIFYFIYDSGRNLKKYKKLLIILCTSIPLILCMRYPIYM
CCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
DENCIHDLRQIPVIVGTLYGGFPVGITLFAILLITRFSFYGFSILTIVVYGTMFIITAFA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAKFNTYNRKIKVAYAMFLTFFLAIFTTVIVLTLSDFEVNNLYIIYFIILPTVLMLFVVY
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEEEHHHHHHHHHHHHHHHH
FNEVLKDAVCMRSKLIKMEKMEIVSQLAASISHEVRNPLTVVKGFTQLLKTPNLTPESRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHH
EYIKHILEELHHAQGIIDDYLTFAKPASEKLDEISVEQELNRVINMILPLCNMNTIHITK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DFSTATIVGNKQHFQQCFLNLLKNGIEAMPNGGTLHISSSISNNKVIIRIEDSGIGMSQE
CCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCHH
QINRFGEPYFSTKTKGTGLGTMVAVKIIETMHGSLKIRSVMNKGTTLTITFPKCNKNASN
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCCC
NK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8497199; 9274030; 9384377 [H]