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The map label for this gene is ltrA [H]

Identifier: 222095795

GI number: 222095795

Start: 2103544

End: 2105367

Strand: Direct

Name: ltrA [H]

Synonym: BCQ_2135

Alternate gene names: 222095795

Gene position: 2103544-2105367 (Clockwise)

Preceding gene: 222095794

Following gene: 222095796

Centisome position: 40.34

GC content: 32.79

Gene sequence:

>1824_bases
ATGGTGGATACCATGAGAGAACCAAGAATGATATTAGACGCATTGACAAAAAATGCCGTTAAAGAAAATTATATCTTCAC
CCGATTATACCGAAATTTATATAACAAAAAATTCTTTCTGGATGCTTACGGGAATATATACCATAAACCAGGTAATATGA
CACAAGGAACCGATAAAGAAACGATTGACGGTTTCTCTATGGATTGGATTGAAAACATTATCTCTTCTTTGAAAGATGAA
TCTTATAAACCTAATCCCTCTAGAAGAGTTTATATCCCTAAGAAAGATGATAAACAACGACCACTTGGTATTCCATCAAT
AAAGGATAAAATCATTCAAGAAGTGGTGAAAGAAATATTGGTTAGTATGTACGAACCCATATTCTCTAAAGCTTCACATG
GTTTTAGACCAAACAAAAGTTGTCACTCAGCATTGAATGACATTAAAATGACGTTTGGTGGAATCAAATGGTGGATTGAG
GGAGATATTAAAGGTTTCTTTGATAATATCGACCATCATGTACTAATAGGGATTCTAAGGAAAAGAATTAAAGATGAAAA
ATTCATCAAACTAATTTGGAAATTCTTGAAAGCAGGATATATGGAAGATTGGAAATTCAATAAAACTTTCAGTGGTACTC
CACAAGGCGGTATCATCAGTCCTGTTCTAGCAAATATATACTTACATGAATTAGATGCTTTTATGGAAAAACAAATTATA
AAATTTGATGAAGGTAAAAGAAGAAGAGATAACCCCGTCTATAAAAAATATAATACGGCTATATGGTATAGAAAAAATAA
GTTGAAAGAAAAATGGAATACGTTGAATGATGATGAAAGAAAAGAATTACAAAGCGAAATATCCACATTAGAAAAAGAAA
GAGAAAAACACTCAGCCGTAGACAACATGGATGCTTCGTTTAAACGATTAAAATACGTAAGATACGCCGATGATTTTGTA
GTTGGTGTGATTGGTTCTAAAGAAGACTCGAAACGGATTAAGGAAGAAATAACCGAATTTCTTCATACATCGTTGAAATT
AGAACTCTCACAAGAAAAAACCCTAATAACCAGTAATAAAAACCTTATAAAGTTTCTTGGTTATGAAATCGGAATTGATG
GTGGTCATGACTCTAAAACTAACACAAATGGCATTAAGAAAAGACATCTGTCAGGAAAACCCATGTTATATCTTCCTTAC
AATAACATGAGAAATTTCTTACTCAAGAATGACTACATGAAAATTGAGGGAAACGATTGGAAACCTGTGCATAGAAGATA
CCTAGTCAATCAAGATGACATCGAAATACTGTCTACCTATAACGCCGAAATTAGAGGGTTTTATGAATACTATAAAATGG
CTATTAACGTGTATAAATTAAATGGTGCTTTTCACATCATCAAAACGAGTTTCGCCAAAACAATGGCAAACAAATATAAA
TTATCGGTTAATAGAGTGTTTAGAAAATACAGTGTAAACGGTGTACTGGGAGTTTTCTACGATACAAAGAATGGGAAGAA
ATTCAGACCATTCTATAACGATGGATTCAAAATGGATAAACAATATAGCAAATCTCTCTCAATTGATACCTTACCTAACA
CTAATATATATAGTGGACGCACTTCACTTGTTTCTCGTCTGTTGGCATCAAAATGTGAATTTTGTGGAACTACAGAAGGG
AAATTTGAAGTACATCATGTACGTAAACTGAAGGACTTGAAAGGTAAGAAAAAGTGGGAGCAAAAAATGATTGCTAGAAA
TCGCAAAACAATGGTTTTGTGTATAAATTGCCATGTTGACCTACATCGTGGGAAACTAGATTAA

Upstream 100 bases:

>100_bases
TCTATGGTAACGGAGTTCTCGTAGTAGTCCGAGATAGGGAAAGCCTATTACATGGCGAAGGAGAACAGTTTATTTCTGTC
TAATTAAAATTGAAAGGTTG

Downstream 100 bases:

>100_bases
ATGTCAATGTCATGAAATAAATGGAGAGCCGTATACATTGAGAGGTGTACGTACGGTTCGGGGGAGGGTTCCTGAAAACC
TAATAACGTAAGTTATCAAG

Product: reverse transcriptase

Products: NA

Alternate protein names: Reverse-transcriptase; RNA maturase; DNA endonuclease [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MVDTMREPRMILDALTKNAVKENYIFTRLYRNLYNKKFFLDAYGNIYHKPGNMTQGTDKETIDGFSMDWIENIISSLKDE
SYKPNPSRRVYIPKKDDKQRPLGIPSIKDKIIQEVVKEILVSMYEPIFSKASHGFRPNKSCHSALNDIKMTFGGIKWWIE
GDIKGFFDNIDHHVLIGILRKRIKDEKFIKLIWKFLKAGYMEDWKFNKTFSGTPQGGIISPVLANIYLHELDAFMEKQII
KFDEGKRRRDNPVYKKYNTAIWYRKNKLKEKWNTLNDDERKELQSEISTLEKEREKHSAVDNMDASFKRLKYVRYADDFV
VGVIGSKEDSKRIKEEITEFLHTSLKLELSQEKTLITSNKNLIKFLGYEIGIDGGHDSKTNTNGIKKRHLSGKPMLYLPY
NNMRNFLLKNDYMKIEGNDWKPVHRRYLVNQDDIEILSTYNAEIRGFYEYYKMAINVYKLNGAFHIIKTSFAKTMANKYK
LSVNRVFRKYSVNGVLGVFYDTKNGKKFRPFYNDGFKMDKQYSKSLSIDTLPNTNIYSGRTSLVSRLLASKCEFCGTTEG
KFEVHHVRKLKDLKGKKKWEQKMIARNRKTMVLCINCHVDLHRGKLD

Sequences:

>Translated_607_residues
MVDTMREPRMILDALTKNAVKENYIFTRLYRNLYNKKFFLDAYGNIYHKPGNMTQGTDKETIDGFSMDWIENIISSLKDE
SYKPNPSRRVYIPKKDDKQRPLGIPSIKDKIIQEVVKEILVSMYEPIFSKASHGFRPNKSCHSALNDIKMTFGGIKWWIE
GDIKGFFDNIDHHVLIGILRKRIKDEKFIKLIWKFLKAGYMEDWKFNKTFSGTPQGGIISPVLANIYLHELDAFMEKQII
KFDEGKRRRDNPVYKKYNTAIWYRKNKLKEKWNTLNDDERKELQSEISTLEKEREKHSAVDNMDASFKRLKYVRYADDFV
VGVIGSKEDSKRIKEEITEFLHTSLKLELSQEKTLITSNKNLIKFLGYEIGIDGGHDSKTNTNGIKKRHLSGKPMLYLPY
NNMRNFLLKNDYMKIEGNDWKPVHRRYLVNQDDIEILSTYNAEIRGFYEYYKMAINVYKLNGAFHIIKTSFAKTMANKYK
LSVNRVFRKYSVNGVLGVFYDTKNGKKFRPFYNDGFKMDKQYSKSLSIDTLPNTNIYSGRTSLVSRLLASKCEFCGTTEG
KFEVHHVRKLKDLKGKKKWEQKMIARNRKTMVLCINCHVDLHRGKLD
>Mature_607_residues
MVDTMREPRMILDALTKNAVKENYIFTRLYRNLYNKKFFLDAYGNIYHKPGNMTQGTDKETIDGFSMDWIENIISSLKDE
SYKPNPSRRVYIPKKDDKQRPLGIPSIKDKIIQEVVKEILVSMYEPIFSKASHGFRPNKSCHSALNDIKMTFGGIKWWIE
GDIKGFFDNIDHHVLIGILRKRIKDEKFIKLIWKFLKAGYMEDWKFNKTFSGTPQGGIISPVLANIYLHELDAFMEKQII
KFDEGKRRRDNPVYKKYNTAIWYRKNKLKEKWNTLNDDERKELQSEISTLEKEREKHSAVDNMDASFKRLKYVRYADDFV
VGVIGSKEDSKRIKEEITEFLHTSLKLELSQEKTLITSNKNLIKFLGYEIGIDGGHDSKTNTNGIKKRHLSGKPMLYLPY
NNMRNFLLKNDYMKIEGNDWKPVHRRYLVNQDDIEILSTYNAEIRGFYEYYKMAINVYKLNGAFHIIKTSFAKTMANKYK
LSVNRVFRKYSVNGVLGVFYDTKNGKKFRPFYNDGFKMDKQYSKSLSIDTLPNTNIYSGRTSLVSRLLASKCEFCGTTEG
KFEVHHVRKLKDLKGKKKWEQKMIARNRKTMVLCINCHVDLHRGKLD

Specific function: Multifunctional protein that promotes group II intron splicing and mobility by acting both on RNA and DNA. It has three activities:reverse transcriptase (RT) for intron duplication, maturase to promote splicing, and DNA endonuclease for site- specific cle

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6226520, Length=591, Percent_Identity=33.6717428087986, Blast_Score=292, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6226521, Length=608, Percent_Identity=31.7434210526316, Blast_Score=266, Evalue=8e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003615
- InterPro:   IPR002866
- InterPro:   IPR000477 [H]

Pfam domain/function: PF01348 Intron_maturas2; PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 71316; Mature: 71316

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDTMREPRMILDALTKNAVKENYIFTRLYRNLYNKKFFLDAYGNIYHKPGNMTQGTDKE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEECCCCCCCCCCCH
TIDGFSMDWIENIISSLKDESYKPNPSRRVYIPKKDDKQRPLGIPSIKDKIIQEVVKEIL
HCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
VSMYEPIFSKASHGFRPNKSCHSALNDIKMTFGGIKWWIEGDIKGFFDNIDHHVLIGILR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCHHHHHHHHH
KRIKDEKFIKLIWKFLKAGYMEDWKFNKTFSGTPQGGIISPVLANIYLHELDAFMEKQII
HHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KFDEGKRRRDNPVYKKYNTAIWYRKNKLKEKWNTLNDDERKELQSEISTLEKEREKHSAV
HCCCCCCCCCCCCHHHHCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DNMDASFKRLKYVRYADDFVVGVIGSKEDSKRIKEEITEFLHTSLKLELSQEKTLITSNK
HCCCHHHHHHHHHEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCC
NLIKFLGYEIGIDGGHDSKTNTNGIKKRHLSGKPMLYLPYNNMRNFLLKNDYMKIEGNDW
CHHHHHCEEEECCCCCCCCCCCCCHHHHCCCCCCEEEECCHHHHHHHCCCCEEEEECCCC
KPVHRRYLVNQDDIEILSTYNAEIRGFYEYYKMAINVYKLNGAFHIIKTSFAKTMANKYK
CHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHEEEEEECCEEEEHHHHHHHHHHHHHH
LSVNRVFRKYSVNGVLGVFYDTKNGKKFRPFYNDGFKMDKQYSKSLSIDTLPNTNIYSGR
HHHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCH
TSLVSRLLASKCEFCGTTEGKFEVHHVRKLKDLKGKKKWEQKMIARNRKTMVLCINCHVD
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEEEE
LHRGKLD
ECCCCCC
>Mature Secondary Structure
MVDTMREPRMILDALTKNAVKENYIFTRLYRNLYNKKFFLDAYGNIYHKPGNMTQGTDKE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEECCCCCCCCCCCH
TIDGFSMDWIENIISSLKDESYKPNPSRRVYIPKKDDKQRPLGIPSIKDKIIQEVVKEIL
HCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
VSMYEPIFSKASHGFRPNKSCHSALNDIKMTFGGIKWWIEGDIKGFFDNIDHHVLIGILR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHCCCHHHHHHHHH
KRIKDEKFIKLIWKFLKAGYMEDWKFNKTFSGTPQGGIISPVLANIYLHELDAFMEKQII
HHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
KFDEGKRRRDNPVYKKYNTAIWYRKNKLKEKWNTLNDDERKELQSEISTLEKEREKHSAV
HCCCCCCCCCCCCHHHHCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DNMDASFKRLKYVRYADDFVVGVIGSKEDSKRIKEEITEFLHTSLKLELSQEKTLITSNK
HCCCHHHHHHHHHEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEECCC
NLIKFLGYEIGIDGGHDSKTNTNGIKKRHLSGKPMLYLPYNNMRNFLLKNDYMKIEGNDW
CHHHHHCEEEECCCCCCCCCCCCCHHHHCCCCCCEEEECCHHHHHHHCCCCEEEEECCCC
KPVHRRYLVNQDDIEILSTYNAEIRGFYEYYKMAINVYKLNGAFHIIKTSFAKTMANKYK
CHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHEEEEEECCEEEEHHHHHHHHHHHHHH
LSVNRVFRKYSVNGVLGVFYDTKNGKKFRPFYNDGFKMDKQYSKSLSIDTLPNTNIYSGR
HHHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCH
TSLVSRLLASKCEFCGTTEGKFEVHHVRKLKDLKGKKKWEQKMIARNRKTMVLCINCHVD
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEEEEEE
LHRGKLD
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655550; 11157264; 10488339; 9353259; 10413481; 11731786 [H]