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The map label for this gene is yhdP [H]

Identifier: 222095704

GI number: 222095704

Start: 2021609

End: 2022916

Strand: Reverse

Name: yhdP [H]

Synonym: BCQ_2044

Alternate gene names: 222095704

Gene position: 2022916-2021609 (Counterclockwise)

Preceding gene: 222095705

Following gene: 222095703

Centisome position: 38.8

GC content: 34.4

Gene sequence:

>1308_bases
TTGGACATATTAAATATTTTTCTCATCTTTGTTCTTATCCTTATTTCCGGCTTTTTCGTTGCATCAGAATTTGCTGTTGT
AAAAGTACGAAAAAGTCGAATTGACCAGCTTGCAAACGAAGGCAATAAACAAGCTTTAGCTGCAAGAAGTGTCATTTCTA
ATTTAGATGTTTATTTATCAGCTTGTCAGCTCGGGATTACAATTACTTCTTTAGGGCTTGGTTGGCTTGGTGAACCGACT
GTGGAACATTTACTACGACCGCTCTTTGAAAAGATTAATATTACTGGAACAATGGCAAATACTTTATCATTTATTATTGC
TTTTAGTGTGATTACATTTTTCCATGTTGTATTAGGTGAATTAGTTCCAAAGTCATTCGCAATTCAAAAAGCAGAGGCGA
TTACGCTTAAGTTTGCACGACCACTTATTTTATTTGATAAAATTATGTACCCGTTCATTTGGTTACTTAATAGTACTGCT
ATCTTTTTCACAAAACTACTCGGTTTAGAACCTGCGAAAGAAAATGAACTTGCCCATTCTGAAGAGGAACTACGACTCAT
TTTAGGTGAAAGTTTCAAAAGCGGCGAAATAAATCAAACCGAATATAAATATGTAAATAATATTTTTGAATTTGACGACC
GAGTTGCGAAAGAAATTATGGTCCCTCGTACAGAAATGATTTGCTTATCTACTGAAAATACGTTAGAAGAAAATATGGAT
ATCGTCGCAACTGAAAAGTATACACGCTACCCTATCATCGAAAAAGATAAAGATGATATTATCGGTATGATCAATACGAA
AGAAGTATTTCACGATCAAACGAAAGGCATTCATAAGCCACTTGAATCTTACATACATCCAGTACTAACTGTATTTGAAA
CTGTTCCAATTCGTAAAACACTGGTACATCTACAAAAGAATCGCGTTCAGATGGCAATCGTTATGGATGAATATGGTGGT
ACTGCTGGACTTTTAACAATGGAAGATATTCTTGAAGAAATCATTGGAGAAATTCAAGATGAGTTTGATGCAGATGAATC
ACCTATGATTGAAAAACGTACACCTAAACTTACTGTTCTAGATGGAAAAGTACTTATTTCTGAAGTAAATGATATGTTTG
GCCTACATATTGATGAGAGCGACTTAGATACAATTGGAGGCTGGCTATTATCGCAAGCAGTTGACGTAAATATTGAAGCT
GGCTACTCCATCGAATATGCCGGTTTTCAATTTAAGGCATTAGAACTTGATGGACATCAAGTCAAAAAAATTGCTGTACA
TAAATTAGATATACAAAAGGAGTTATAA

Upstream 100 bases:

>100_bases
TTTTTCTTTGACTATTCTTTTCATTTGGATTTATTATAAAAGTATAACATAATTGCAGGAGGTGACATCTTTATTCCAAA
CGACGGAATAGAGAATACAC

Downstream 100 bases:

>100_bases
AGTGACTGTTTTCTTAACAATCTGTATCATTGCCTGTTTCATTATTTCATTTCTAGCTTTTATTTATCCTATTATCCCGG
GCATCCTAGCTGTCTGGGCT

Product: hemolysin-like protein (cbs domain protein)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MDILNIFLIFVLILISGFFVASEFAVVKVRKSRIDQLANEGNKQALAARSVISNLDVYLSACQLGITITSLGLGWLGEPT
VEHLLRPLFEKINITGTMANTLSFIIAFSVITFFHVVLGELVPKSFAIQKAEAITLKFARPLILFDKIMYPFIWLLNSTA
IFFTKLLGLEPAKENELAHSEEELRLILGESFKSGEINQTEYKYVNNIFEFDDRVAKEIMVPRTEMICLSTENTLEENMD
IVATEKYTRYPIIEKDKDDIIGMINTKEVFHDQTKGIHKPLESYIHPVLTVFETVPIRKTLVHLQKNRVQMAIVMDEYGG
TAGLLTMEDILEEIIGEIQDEFDADESPMIEKRTPKLTVLDGKVLISEVNDMFGLHIDESDLDTIGGWLLSQAVDVNIEA
GYSIEYAGFQFKALELDGHQVKKIAVHKLDIQKEL

Sequences:

>Translated_435_residues
MDILNIFLIFVLILISGFFVASEFAVVKVRKSRIDQLANEGNKQALAARSVISNLDVYLSACQLGITITSLGLGWLGEPT
VEHLLRPLFEKINITGTMANTLSFIIAFSVITFFHVVLGELVPKSFAIQKAEAITLKFARPLILFDKIMYPFIWLLNSTA
IFFTKLLGLEPAKENELAHSEEELRLILGESFKSGEINQTEYKYVNNIFEFDDRVAKEIMVPRTEMICLSTENTLEENMD
IVATEKYTRYPIIEKDKDDIIGMINTKEVFHDQTKGIHKPLESYIHPVLTVFETVPIRKTLVHLQKNRVQMAIVMDEYGG
TAGLLTMEDILEEIIGEIQDEFDADESPMIEKRTPKLTVLDGKVLISEVNDMFGLHIDESDLDTIGGWLLSQAVDVNIEA
GYSIEYAGFQFKALELDGHQVKKIAVHKLDIQKEL
>Mature_435_residues
MDILNIFLIFVLILISGFFVASEFAVVKVRKSRIDQLANEGNKQALAARSVISNLDVYLSACQLGITITSLGLGWLGEPT
VEHLLRPLFEKINITGTMANTLSFIIAFSVITFFHVVLGELVPKSFAIQKAEAITLKFARPLILFDKIMYPFIWLLNSTA
IFFTKLLGLEPAKENELAHSEEELRLILGESFKSGEINQTEYKYVNNIFEFDDRVAKEIMVPRTEMICLSTENTLEENMD
IVATEKYTRYPIIEKDKDDIIGMINTKEVFHDQTKGIHKPLESYIHPVLTVFETVPIRKTLVHLQKNRVQMAIVMDEYGG
TAGLLTMEDILEEIIGEIQDEFDADESPMIEKRTPKLTVLDGKVLISEVNDMFGLHIDESDLDTIGGWLLSQAVDVNIEA
GYSIEYAGFQFKALELDGHQVKKIAVHKLDIQKEL

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=394, Percent_Identity=48.9847715736041, Blast_Score=392, Evalue=1e-109,
Organism=Escherichia coli, GI1790664, Length=434, Percent_Identity=22.5806451612903, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI145693175, Length=418, Percent_Identity=23.9234449760766, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786879, Length=270, Percent_Identity=29.6296296296296, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082033, Length=232, Percent_Identity=22.4137931034483, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788119, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49181; Mature: 49181

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILNIFLIFVLILISGFFVASEFAVVKVRKSRIDQLANEGNKQALAARSVISNLDVYLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ACQLGITITSLGLGWLGEPTVEHLLRPLFEKINITGTMANTLSFIIAFSVITFFHVVLGE
HHHHCEEHECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVPKSFAIQKAEAITLKFARPLILFDKIMYPFIWLLNSTAIFFTKLLGLEPAKENELAHS
HCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCC
EEELRLILGESFKSGEINQTEYKYVNNIFEFDDRVAKEIMVPRTEMICLSTENTLEENMD
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCC
IVATEKYTRYPIIEKDKDDIIGMINTKEVFHDQTKGIHKPLESYIHPVLTVFETVPIRKT
EEEECCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LVHLQKNRVQMAIVMDEYGGTAGLLTMEDILEEIIGEIQDEFDADESPMIEKRTPKLTVL
HHHHHHCCEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
DGKVLISEVNDMFGLHIDESDLDTIGGWLLSQAVDVNIEAGYSIEYAGFQFKALELDGHQ
CCHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHEEEEECCCEEEECCEEEEEEECCCHH
VKKIAVHKLDIQKEL
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MDILNIFLIFVLILISGFFVASEFAVVKVRKSRIDQLANEGNKQALAARSVISNLDVYLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ACQLGITITSLGLGWLGEPTVEHLLRPLFEKINITGTMANTLSFIIAFSVITFFHVVLGE
HHHHCEEHECCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVPKSFAIQKAEAITLKFARPLILFDKIMYPFIWLLNSTAIFFTKLLGLEPAKENELAHS
HCCHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCC
EEELRLILGESFKSGEINQTEYKYVNNIFEFDDRVAKEIMVPRTEMICLSTENTLEENMD
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCC
IVATEKYTRYPIIEKDKDDIIGMINTKEVFHDQTKGIHKPLESYIHPVLTVFETVPIRKT
EEEECCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LVHLQKNRVQMAIVMDEYGGTAGLLTMEDILEEIIGEIQDEFDADESPMIEKRTPKLTVL
HHHHHHCCEEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
DGKVLISEVNDMFGLHIDESDLDTIGGWLLSQAVDVNIEAGYSIEYAGFQFKALELDGHQ
CCHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHEEEEECCCEEEECCEEEEEEECCCHH
VKKIAVHKLDIQKEL
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]