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The map label for this gene is nagA [H]

Identifier: 222095653

GI number: 222095653

Start: 1972442

End: 1973590

Strand: Direct

Name: nagA [H]

Synonym: BCQ_1993

Alternate gene names: 222095653

Gene position: 1972442-1973590 (Clockwise)

Preceding gene: 222095652

Following gene: 222095654

Centisome position: 37.83

GC content: 39.77

Gene sequence:

>1149_bases
ATGTCTATTTTTATCTTTGCAGATAAGTTTTTTCTTGAGGGGAAGGTCGTAGGTCCTGGTTTTTTGGAGATAAAAGATGG
AAAATTCGGTATCTTTTTAGAGAACAGGCCAGAAGAAGTGGAAGAAATCATTGATTATGCAGGATATTGGATTGCTCCTG
GTCTAGTGGATACACATATTCATGGTTTTAGAAATCACGACGTTATGGACAATAATTTTGAAGGACTAAATCAAATATCG
GTAGGACTCCTTTCTTGCGGCGTTACATCCTTTTTACCGACAACTTTAACATCCTCAATAGAATCGTTGAATAATGTCGT
TGAAATGATTGGTGCCAATTACAAGAAAGTACAGGGCGCAAAAATTAAAGGGATCTTTTTAGAAGGGCCGTTTTTTACTG
AAAAGCATAAAGGAGCACAAAACACGAAATATTTTTGTGACCCATCAGTTGATATGTTGAAAGGTTGGCAGAAATTATCA
AATGATTCTATTAAAAAAATTGCGATTGCACCTGAAAGAAAAGGAGCAGCGGAATTCATTGAATATGCTGTAGGAGAAGA
GATTATAGTAGCATTGGCCCATAGTGATGCAACTTATGAAGAAGCCAAGCAAGCTAGTGAAAAAGGCGCATCCGTTTTTG
TTCATACTTTCAATGGTATGAGTCCGCTGCACCATCGTGAGCCAGGGATGGTTGGAGCAGCCATGAATTTAAAAGATGTT
TTTACCGAAATCATATGTGATGGACATCATGTTCATCCTGTTGCTTTAAATATTTTAATGAATGTCCGTGGCAGAGAAGA
GGTTGTAATGGTATCCGATTGTATGATGGCCGGAGGTATGACTGAAGGAACGTATCAACTTGGAGAATTTCCTGTGAAAG
TAAAAGGTGGGATGGCTTGTTTGGAAAGCGGAAGTTTAGCAGGTAGCATTTTGCAATTAAAAGATGCTGTCAAAAATGTC
GTCGATTGGGGAATTGCCGCGCCCGAGCAAGCAATTTACATGGCGAGTACTGCACCAGCTAAAAGTATTCAACTAGATGG
CGAATGTGGGAAAATCGCTGAGGGGTATGCTGCTGACTTTATAGTACTGACGCCAGCGATGGATTTAGCAGCTACCTATC
TTGATGGTGTGTGCCGTTTTCAAGCTTAA

Upstream 100 bases:

>100_bases
GTAATACACCAGATACACCTTCACCGACAGGAACGGTGAACCGTGTCGTTAAAGGTGTTACTATCTACGAATATGAGTAA
CTAGGGTAGGGGAAACATAC

Downstream 100 bases:

>100_bases
ATATTTTTCTGAAAGAGGGATTTCAAATGATTTTATCTGTCACCATGAATCCATCTGTCGATATTTCCTATTCGACTCAT
GAATTAAAGTTAGATGTTGT

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSIFIFADKFFLEGKVVGPGFLEIKDGKFGIFLENRPEEVEEIIDYAGYWIAPGLVDTHIHGFRNHDVMDNNFEGLNQIS
VGLLSCGVTSFLPTTLTSSIESLNNVVEMIGANYKKVQGAKIKGIFLEGPFFTEKHKGAQNTKYFCDPSVDMLKGWQKLS
NDSIKKIAIAPERKGAAEFIEYAVGEEIIVALAHSDATYEEAKQASEKGASVFVHTFNGMSPLHHREPGMVGAAMNLKDV
FTEIICDGHHVHPVALNILMNVRGREEVVMVSDCMMAGGMTEGTYQLGEFPVKVKGGMACLESGSLAGSILQLKDAVKNV
VDWGIAAPEQAIYMASTAPAKSIQLDGECGKIAEGYAADFIVLTPAMDLAATYLDGVCRFQA

Sequences:

>Translated_382_residues
MSIFIFADKFFLEGKVVGPGFLEIKDGKFGIFLENRPEEVEEIIDYAGYWIAPGLVDTHIHGFRNHDVMDNNFEGLNQIS
VGLLSCGVTSFLPTTLTSSIESLNNVVEMIGANYKKVQGAKIKGIFLEGPFFTEKHKGAQNTKYFCDPSVDMLKGWQKLS
NDSIKKIAIAPERKGAAEFIEYAVGEEIIVALAHSDATYEEAKQASEKGASVFVHTFNGMSPLHHREPGMVGAAMNLKDV
FTEIICDGHHVHPVALNILMNVRGREEVVMVSDCMMAGGMTEGTYQLGEFPVKVKGGMACLESGSLAGSILQLKDAVKNV
VDWGIAAPEQAIYMASTAPAKSIQLDGECGKIAEGYAADFIVLTPAMDLAATYLDGVCRFQA
>Mature_381_residues
SIFIFADKFFLEGKVVGPGFLEIKDGKFGIFLENRPEEVEEIIDYAGYWIAPGLVDTHIHGFRNHDVMDNNFEGLNQISV
GLLSCGVTSFLPTTLTSSIESLNNVVEMIGANYKKVQGAKIKGIFLEGPFFTEKHKGAQNTKYFCDPSVDMLKGWQKLSN
DSIKKIAIAPERKGAAEFIEYAVGEEIIVALAHSDATYEEAKQASEKGASVFVHTFNGMSPLHHREPGMVGAAMNLKDVF
TEIICDGHHVHPVALNILMNVRGREEVVMVSDCMMAGGMTEGTYQLGEFPVKVKGGMACLESGSLAGSILQLKDAVKNVV
DWGIAAPEQAIYMASTAPAKSIQLDGECGKIAEGYAADFIVLTPAMDLAATYLDGVCRFQA

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=395, Percent_Identity=29.873417721519, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI224922791, Length=389, Percent_Identity=29.8200514138817, Blast_Score=148, Evalue=7e-36,
Organism=Escherichia coli, GI1786892, Length=344, Percent_Identity=27.0348837209302, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17553768, Length=377, Percent_Identity=30.2387267904509, Blast_Score=151, Evalue=5e-37,
Organism=Drosophila melanogaster, GI19920392, Length=375, Percent_Identity=33.6, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI281361140, Length=401, Percent_Identity=32.1695760598504, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41462; Mature: 41331

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIFIFADKFFLEGKVVGPGFLEIKDGKFGIFLENRPEEVEEIIDYAGYWIAPGLVDTHI
CEEEEEEEEEEEECEEECCCEEEEECCEEEEEECCCHHHHHHHHHHCCCEECCCCHHHHC
HGFRNHDVMDNNFEGLNQISVGLLSCGVTSFLPTTLTSSIESLNNVVEMIGANYKKVQGA
CCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
KIKGIFLEGPFFTEKHKGAQNTKYFCDPSVDMLKGWQKLSNDSIKKIAIAPERKGAAEFI
EEEEEEEECCCCCHHCCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
EYAVGEEIIVALAHSDATYEEAKQASEKGASVFVHTFNGMSPLHHREPGMVGAAMNLKDV
HHHCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEECCCHHHH
FTEIICDGHHVHPVALNILMNVRGREEVVMVSDCMMAGGMTEGTYQLGEFPVKVKGGMAC
HHHHHCCCCCCCCEEEEEHHCCCCCCCEEEEEHHHHHCCCCCCCEECCCCCEEECCCCCE
LESGSLAGSILQLKDAVKNVVDWGIAAPEQAIYMASTAPAKSIQLDGECGKIAEGYAADF
ECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCE
IVLTPAMDLAATYLDGVCRFQA
EEECCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIFIFADKFFLEGKVVGPGFLEIKDGKFGIFLENRPEEVEEIIDYAGYWIAPGLVDTHI
EEEEEEEEEEEECEEECCCEEEEECCEEEEEECCCHHHHHHHHHHCCCEECCCCHHHHC
HGFRNHDVMDNNFEGLNQISVGLLSCGVTSFLPTTLTSSIESLNNVVEMIGANYKKVQGA
CCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
KIKGIFLEGPFFTEKHKGAQNTKYFCDPSVDMLKGWQKLSNDSIKKIAIAPERKGAAEFI
EEEEEEEECCCCCHHCCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHH
EYAVGEEIIVALAHSDATYEEAKQASEKGASVFVHTFNGMSPLHHREPGMVGAAMNLKDV
HHHCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEECCCHHHH
FTEIICDGHHVHPVALNILMNVRGREEVVMVSDCMMAGGMTEGTYQLGEFPVKVKGGMAC
HHHHHCCCCCCCCEEEEEHHCCCCCCCEEEEEHHHHHCCCCCCCEECCCCCEEECCCCCE
LESGSLAGSILQLKDAVKNVVDWGIAAPEQAIYMASTAPAKSIQLDGECGKIAEGYAADF
ECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCE
IVLTPAMDLAATYLDGVCRFQA
EEECCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969210 [H]