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The map label for this gene is lytF [H]

Identifier: 222095604

GI number: 222095604

Start: 1923792

End: 1925012

Strand: Direct

Name: lytF [H]

Synonym: BCQ_1944

Alternate gene names: 222095604

Gene position: 1923792-1925012 (Clockwise)

Preceding gene: 222095602

Following gene: 222095606

Centisome position: 36.9

GC content: 38.49

Gene sequence:

>1221_bases
ATGGATTCTGCTCATGCACAAGTTTCAAACGAAGCGCTAAAAGAAATTAATGGACAAACTCAAACACAAACGACTGTAAC
TGAAACAAAAACTGTAGAAACAAAATCCGACTTAAAATACACAGTAACTGCTGATGTATTAAATGTTCGTTCAGGTGCTG
GTACAGGACATAGCGTTATTTCTAAAGTAAAACAAGGTCAAGTACTACAAGTAATTGGACAAGAAAACGGTTGGTTCAAA
GTAACTGTAAACGGTCAAACTGGTTATGTAAGTGGTGACTTCGTAACGACTGGTGGTAAAACAGGAACTACTGTTCAACA
AGGAACTGGTACTTACACAGTAAACGTTTCTTCACTTAACGTACGTACAGGCCCAAGTACATCTCATACAGTATTAGGCT
CTGTAAATAAAGGTAAAACAGTACAAGTTGTTGGTGAAGTACAAGATTGGTTTAAAATCAACTTCAATGGTGGAACTGGA
TACGTAAGCAAAGACTTCGTAACAAAAGGTGGTTCTGCTGTATCTAACCAAACACAACAACCAACTACAAACAACAATAC
TACTACAGTTCAAACTGGTGGTTCTTATGTTGTTAACACTGGTGCTTTAAAAGTACGTACAGGCCCAGCTACATACAACG
CTGTAATCGGTGGTGTAACAAACGGTACAGTATTAAACGTTACTGGCGCTGAAAATGGTTGGTACAAAATTAACCATAAC
GGCCGCACAGGTTACGTAAGTGCAGACTTCGTTAAGTTTGTAAAAGGCGGAGTAAACAACGTTACAAATAACAATAACGT
TACAAATAACGTTCAACAACCAGGTAAAGACGTACAAAAACCAACAACTGGTGGAGATACATCTTCAATCGCTGGATTCG
CTAGATCATTAAATGGTTCACCATACAGAACAGCTGGTACAACACCTGCTGGTTTTGATTGCAGTGGATTCATTCACTAC
GTATTAAATCAAACTGGTCATAAAGGCGCTCGTCAAACAGTTGCTGGATACTGGAGTTCTAAAACAAAAACTAGCAATCC
ACAACCAGGTGATTTAGTATACTTCCAAAACACTTATAAATCAGGTCCTTCTCACATGGGTGTTTACTTAGGAAACGGTC
AGTTCATTAGTGCAGAAACTGATGCAACTGGTGTACGTATTAGTTCTGTAAGTAACTCTTACTGGAGCAAGCACCTATTA
GGTTACACAAAAGCATACTAA

Upstream 100 bases:

>100_bases
TTTTTAAGAGGATAGTAGGGAAAGGAAGTAAAGACAACTTATGAAAAAAGTAATTGCAGGTTTAGCAGTAGCTTCAGTAG
CAGGTGTTGCAGTTCCAGGT

Downstream 100 bases:

>100_bases
GAAAAAGTAAATTATATACTTTTCGTATAGAGAAAAGGCTTTCCAGGGAAACTTGGGAAGCCTTTTTATAGTTTAATAAA
TTGGGATGTAATAGTTTTTA

Product: nlp/p60 family protein

Products: NA

Alternate protein names: Cell wall-associated polypeptide CWBP49; Gamma-D-glutamate-meso-diaminopimelate muropeptidase lytF [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MDSAHAQVSNEALKEINGQTQTQTTVTETKTVETKSDLKYTVTADVLNVRSGAGTGHSVISKVKQGQVLQVIGQENGWFK
VTVNGQTGYVSGDFVTTGGKTGTTVQQGTGTYTVNVSSLNVRTGPSTSHTVLGSVNKGKTVQVVGEVQDWFKINFNGGTG
YVSKDFVTKGGSAVSNQTQQPTTNNNTTTVQTGGSYVVNTGALKVRTGPATYNAVIGGVTNGTVLNVTGAENGWYKINHN
GRTGYVSADFVKFVKGGVNNVTNNNNVTNNVQQPGKDVQKPTTGGDTSSIAGFARSLNGSPYRTAGTTPAGFDCSGFIHY
VLNQTGHKGARQTVAGYWSSKTKTSNPQPGDLVYFQNTYKSGPSHMGVYLGNGQFISAETDATGVRISSVSNSYWSKHLL
GYTKAY

Sequences:

>Translated_406_residues
MDSAHAQVSNEALKEINGQTQTQTTVTETKTVETKSDLKYTVTADVLNVRSGAGTGHSVISKVKQGQVLQVIGQENGWFK
VTVNGQTGYVSGDFVTTGGKTGTTVQQGTGTYTVNVSSLNVRTGPSTSHTVLGSVNKGKTVQVVGEVQDWFKINFNGGTG
YVSKDFVTKGGSAVSNQTQQPTTNNNTTTVQTGGSYVVNTGALKVRTGPATYNAVIGGVTNGTVLNVTGAENGWYKINHN
GRTGYVSADFVKFVKGGVNNVTNNNNVTNNVQQPGKDVQKPTTGGDTSSIAGFARSLNGSPYRTAGTTPAGFDCSGFIHY
VLNQTGHKGARQTVAGYWSSKTKTSNPQPGDLVYFQNTYKSGPSHMGVYLGNGQFISAETDATGVRISSVSNSYWSKHLL
GYTKAY
>Mature_406_residues
MDSAHAQVSNEALKEINGQTQTQTTVTETKTVETKSDLKYTVTADVLNVRSGAGTGHSVISKVKQGQVLQVIGQENGWFK
VTVNGQTGYVSGDFVTTGGKTGTTVQQGTGTYTVNVSSLNVRTGPSTSHTVLGSVNKGKTVQVVGEVQDWFKINFNGGTG
YVSKDFVTKGGSAVSNQTQQPTTNNNTTTVQTGGSYVVNTGALKVRTGPATYNAVIGGVTNGTVLNVTGAENGWYKINHN
GRTGYVSADFVKFVKGGVNNVTNNNNVTNNVQQPGKDVQKPTTGGDTSSIAGFARSLNGSPYRTAGTTPAGFDCSGFIHY
VLNQTGHKGARQTVAGYWSSKTKTSNPQPGDLVYFQNTYKSGPSHMGVYLGNGQFISAETDATGVRISSVSNSYWSKHLL
GYTKAY

Specific function: Cleaves gamma-D-glutamate-meso-diaminopimelate bonds. Cell wall hydrolase involved in cell autolysis [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Secreted, cell wall. Note=LysM repeats are thought to be involved in peptidoglycan binding [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=108, Percent_Identity=35.1851851851852, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787944, Length=108, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788501, Length=102, Percent_Identity=40.1960784313725, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 42757; Mature: 42757

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSAHAQVSNEALKEINGQTQTQTTVTETKTVETKSDLKYTVTADVLNVRSGAGTGHSVI
CCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEEEEEEEEEECCCCCCCHHHH
SKVKQGQVLQVIGQENGWFKVTVNGQTGYVSGDFVTTGGKTGTTVQQGTGTYTVNVSSLN
HHHHCCCEEEEEECCCCEEEEEECCCCCEEECCEEECCCCCCCEEECCCCEEEEEEEEEE
VRTGPSTSHTVLGSVNKGKTVQVVGEVQDWFKINFNGGTGYVSKDFVTKGGSAVSNQTQQ
EECCCCCCCEEEECCCCCCEEEEEEECCEEEEEEECCCCCCEEHHHCCCCCCCCCCCCCC
PTTNNNTTTVQTGGSYVVNTGALKVRTGPATYNAVIGGVTNGTVLNVTGAENGWYKINHN
CCCCCCEEEEECCCCEEEECCEEEEEECCCEEEEEEECCCCCEEEEEECCCCCEEEEECC
GRTGYVSADFVKFVKGGVNNVTNNNNVTNNVQQPGKDVQKPTTGGDTSSIAGFARSLNGS
CCEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHCCCC
PYRTAGTTPAGFDCSGFIHYVLNQTGHKGARQTVAGYWSSKTKTSNPQPGDLVYFQNTYK
CCCCCCCCCCCCCHHHHHHEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCC
SGPSHMGVYLGNGQFISAETDATGVRISSVSNSYWSKHLLGYTKAY
CCCCCEEEEECCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSAHAQVSNEALKEINGQTQTQTTVTETKTVETKSDLKYTVTADVLNVRSGAGTGHSVI
CCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEEEEEEEEEECCCCCCCHHHH
SKVKQGQVLQVIGQENGWFKVTVNGQTGYVSGDFVTTGGKTGTTVQQGTGTYTVNVSSLN
HHHHCCCEEEEEECCCCEEEEEECCCCCEEECCEEECCCCCCCEEECCCCEEEEEEEEEE
VRTGPSTSHTVLGSVNKGKTVQVVGEVQDWFKINFNGGTGYVSKDFVTKGGSAVSNQTQQ
EECCCCCCCEEEECCCCCCEEEEEEECCEEEEEEECCCCCCEEHHHCCCCCCCCCCCCCC
PTTNNNTTTVQTGGSYVVNTGALKVRTGPATYNAVIGGVTNGTVLNVTGAENGWYKINHN
CCCCCCEEEEECCCCEEEECCEEEEEECCCEEEEEEECCCCCEEEEEECCCCCEEEEECC
GRTGYVSADFVKFVKGGVNNVTNNNNVTNNVQQPGKDVQKPTTGGDTSSIAGFARSLNGS
CCEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHCCCC
PYRTAGTTPAGFDCSGFIHYVLNQTGHKGARQTVAGYWSSKTKTSNPQPGDLVYFQNTYK
CCCCCCCCCCCCCHHHHHHEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCC
SGPSHMGVYLGNGQFISAETDATGVRISSVSNSYWSKHLLGYTKAY
CCCCCEEEEECCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 10206711 [H]