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The map label for this gene is cat1 [H]

Identifier: 222095523

GI number: 222095523

Start: 1839783

End: 1841297

Strand: Direct

Name: cat1 [H]

Synonym: BCQ_1863

Alternate gene names: 222095523

Gene position: 1839783-1841297 (Clockwise)

Preceding gene: 222095522

Following gene: 222095524

Centisome position: 35.28

GC content: 38.35

Gene sequence:

>1515_bases
ATGGAGAATAATTTGGATAGAATTAGGGATGAACGTCTGAAAGATCGCGTAGTTACACCTGAAGAAGCAGCTTCATGGAT
TGAAAGTGGAATGACTTTAGGCTTAAGTGGGTTTACACGTGCAGGTGATGTAAAAGCAGTCCCATTTGCGCTTGTAAACC
GAGTTAAGAATGATACATCTTTTAAAGTAAATGTTTATACTGGTGCCTCTTTAGGTTCTGATGTAGATAAATTATTTGCG
GAAGCAGGAATTTTAGGGAAAAGATTGCCTTTCCAAGCTGATGCGACTATGCGAAAAGGAATCAATAACGGAGATTTTTT
ATTTGTGGACCAGCACTTATCTCATACATCAGAGTTACTTCGCGCTGACGTTATGGATGTAGATTTTGCTATTTTGGAAG
CGGTTGCGATTACTGAAGATGGCATGATTATTCCAACAACTTCAATAGGAAATTCTTTAGCGTTTTCTTTAAATGCTAAG
TCCATTATTATTGAAATGAATATGGCTCAATCCACGCAGTTAGAAGGACTGCATGATTTATATGAACCAGGTAAACAAGG
AGAAAGACTTCCAATTCCAATTGTGAAAACGGATGATCGAATTGGAACGATTGGCATTCCAATCGATGTTGAAAAGGTGA
AAGGGATTGTGTTTACGAACCAATTAGACTCACCATCGACAATTGTTCCTCCGGATGAAGAAACTGTTATTATGGCACAG
CATTTAATAGAGTTCCTTCGAAAAGAAGTCGAAGTAGGCCGATTAACAAATCGTTTAGCACCATTACAATCAGGAATTGG
CTCAGTGGCTAATGCTGTTCTTCATGGAATGTTAGATTCGGAGTTTGAAGATTTAGAAGTGTATTCTGAAGTTTTACAAG
ATGCGGTCTTTGATCTTATGGATGCTGGAAAAGTCAATTTTGCTTCATGCTGTTCAATCACACTCTCTGAGGAGAAAATG
CAAAAAGTATTTTCCAACTTTGAAAAATATCGTGACAAATTAATGATGCGCCCGCAAGAGATTTCTAATCATCCTGAAAT
CATTCGTCGCCTCGGATTAATCTCGATTAATACTGCTTTAGAATTAGATATATACGGAAATGTGAACTCTACTCACGTTT
TAGGCACAAAAATGATGAATGGTATCGGTGGTTCTGGTGATTTTGCGAGAAATGCTCGCCTAGCTATCTTTGTTACGAAA
TCGATTGCGAAAGGTGGCAACATTTCAAGTATCGTTCCTTTTGTTTCACATGTGGACCATACGGAACACGATGTAGATGT
TATCGTCACTGAACAAGGGTATGTTGATCTAAGAGGACTGGCCCCAAGAGAAAGAGTGGAATTAATTATCGAGAATTGCG
CACATCCAATGTATCGTGATCAGCTAAGAGCTTATTACGAAGAAGCTAAAACGAGAGGTGGACAAACTCCTCATGTTTTA
GAAAAAGCTTTTTCTTGGCATACGAATTATGCTAAAAATGGAACAATGCTTGAGGCGGTAGTAGAAACTGTATAG

Upstream 100 bases:

>100_bases
CTGTTTTGTCTGAATTTTTGCCATTGTATACTGAAATCCCTATTTAGATAATGTTAAAGTGTAAAATAATTATGAATATT
CATAGGGAGAGGGATTACAT

Downstream 100 bases:

>100_bases
GTGTTTATCGTTAGAAATAGTAAAACGAAAGATTGAGTTTGAAAAAATTTTAGAAGAAGAAAACGCCAACTTTCAAAGAT
GGCGTTTTTTCTTTAAATAC

Product: acetyl-CoA hydrolase/transferase family protein

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MENNLDRIRDERLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTSELLRADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSTQLEGLHDLYEPGKQGERLPIPIVKTDDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFVSHVDHTEHDVDVIVTEQGYVDLRGLAPRERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHVL
EKAFSWHTNYAKNGTMLEAVVETV

Sequences:

>Translated_504_residues
MENNLDRIRDERLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTSELLRADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSTQLEGLHDLYEPGKQGERLPIPIVKTDDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFVSHVDHTEHDVDVIVTEQGYVDLRGLAPRERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHVL
EKAFSWHTNYAKNGTMLEAVVETV
>Mature_504_residues
MENNLDRIRDERLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTSFKVNVYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTSELLRADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSTQLEGLHDLYEPGKQGERLPIPIVKTDDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFVSHVDHTEHDVDVIVTEQGYVDLRGLAPRERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHVL
EKAFSWHTNYAKNGTMLEAVVETV

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=41.9753086419753, Blast_Score=390, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17538151, Length=397, Percent_Identity=26.1964735516373, Blast_Score=82, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319456, Length=510, Percent_Identity=41.9607843137255, Blast_Score=395, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55697; Mature: 55697

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNLDRIRDERLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTS
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVNVYTGASLGSDVDKLFAEAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTSELL
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
RADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAKSIIIEMNMAQSTQLEGLHDL
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHH
YEPGKQGERLPIPIVKTDDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HCCCCCCCCCCCEEEECCCCEEEEECCEEHHHHCCEEEECCCCCCCCCCCCCCCHHHHHH
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DAGKVNFASCCSITLSEEKMQKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTAL
HCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHCCEEECCEE
ELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTKSIAKGGNISSIVPFVSHVDH
EEEEECCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHCCC
TEHDVDVIVTEQGYVDLRGLAPRERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHVL
CCCCEEEEEECCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHH
EKAFSWHTNYAKNGTMLEAVVETV
HHHHHHCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MENNLDRIRDERLKDRVVTPEEAASWIESGMTLGLSGFTRAGDVKAVPFALVNRVKNDTS
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVNVYTGASLGSDVDKLFAEAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTSELL
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
RADVMDVDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAKSIIIEMNMAQSTQLEGLHDL
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEECCCCCHHHHHHHHH
YEPGKQGERLPIPIVKTDDRIGTIGIPIDVEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HCCCCCCCCCCCEEEECCCCEEEEECCEEHHHHCCEEEECCCCCCCCCCCCCCCHHHHHH
HLIEFLRKEVEVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DAGKVNFASCCSITLSEEKMQKVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTAL
HCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHCCEEECCEE
ELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTKSIAKGGNISSIVPFVSHVDH
EEEEECCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHCCC
TEHDVDVIVTEQGYVDLRGLAPRERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHVL
CCCCEEEEEECCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHH
EKAFSWHTNYAKNGTMLEAVVETV
HHHHHHCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]