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The map label for this gene is hflX [H]

Identifier: 222095497

GI number: 222095497

Start: 1809897

End: 1811156

Strand: Direct

Name: hflX [H]

Synonym: BCQ_1837

Alternate gene names: 222095497

Gene position: 1809897-1811156 (Clockwise)

Preceding gene: 222095496

Following gene: 222095499

Centisome position: 34.71

GC content: 35.56

Gene sequence:

>1260_bases
ATGGAAGAATTATTACAAAGAGCAGTTTTAGTTGGAGTAAATTTAGGTAATGAGGATGATTTTGCATATTCGATGGAAGA
GCTAACGAATCTTGCAGAAGCTTGTGATGTAGAGGTAATTGGACAAGTGACGCAAAATTTACAACGTGTAAATCCATCCC
ATTATATTGGAAAAGGAAAGATTGAAGAAGTAGCAGCCTATGTAAATGAAGTAGGTGCGAATATGGTCATCTTTAATGAC
GAATTATCGCCTTCTCAAATTCGAAATTTAGAAGCAGATTTAGATTGTAAAGTAATTGACCGTACCATATTAATTTTAGA
CATTTTTGCGCAACGTGCGAAAACGAAAGAAGCGCAGTTGCAAGTAGAGGTGGCCCACCTTCAGTATATGATGCCTCGTT
TAATTGGTCTTCGTGAGTCGTTAGGAAGACAGAGCGGCGGTGTTGGTACGAAAAATAAAGGTGTCGGTGAGAAGAAATTA
GAGTTGGATCGTCGTAAAATTGAAGAACAAATTTCAGTTTTAAATAAAGATTTAGAAGCTCTTGTTGCGCAGCGTCAAAC
GCAGCGAAAGCAACGTAAGAAAAATGAAATTCCTGTTGTAGCATTAGTAGGTTATACGAACGCAGGAAAATCAACGACGA
TGAATGCGATGCTTGAAATTTATAATGGGACAGAAGAAAAACAAGTATTTGAAAAAGATATGTTATTCGCGACGTTAGAA
ACATCGGTGCGAAATATTGATTTACCAGATAATAAATCATTCTTATTAACAGATACAGTTGGATTTGTAAGTAAATTACC
ACATCATCTTGTGAAAGCATTCCGTTCAACGTTAGAAGAAGTAGCGGAAGCAGACTTACTTATTCACGTTGTAGATTATG
CAAATCCGAATTATGAACAGTTAATTGATATTACAAATGAAACGTTAAAGAAAATTGGAGTAGAAAATATTCCAACAATC
TATGCTTATAACAAATCAGATATGGTAGATGTTGAAATTCCGAAAGTACAAGAAGACCGTGTTTATTTATCGGCGAAGAA
ACATGTTGGAATAAAAGAGCTTGTCGAAATGATTCGCTCACACATTTATAAAGAGTATACGAAGTGTGAAATGTTAATTC
CGTATGATCAAGGGCAGGTAGTTTCTTATTTCAATACTCATGCGCACGTTCTATCTACGAGTTATGAAAACGAAGGTACG
AAACTAGAAGTGGAATGTAAGACGAGCGATTACGAAAAGTATAAGCGTTTTGCAATTTAA

Upstream 100 bases:

>100_bases
ACTTTCTTCTATTTCTTTGGTGAACCCTTATCCGTTTACGAAAACACAGGCAGCGACCTGTGTTTTTTATTTTACGTAAT
CGAAATGGAGGAATAAATAT

Downstream 100 bases:

>100_bases
TAAAGAAGGCGATCCTAATATGTTTTAGGATCGCCTTTTTCTTATTCCGTAATAGAGGCCCACTTATAAGAATAAATTCC
TGCAAATGGACGAACAACAA

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MEELLQRAVLVGVNLGNEDDFAYSMEELTNLAEACDVEVIGQVTQNLQRVNPSHYIGKGKIEEVAAYVNEVGANMVIFND
ELSPSQIRNLEADLDCKVIDRTILILDIFAQRAKTKEAQLQVEVAHLQYMMPRLIGLRESLGRQSGGVGTKNKGVGEKKL
ELDRRKIEEQISVLNKDLEALVAQRQTQRKQRKKNEIPVVALVGYTNAGKSTTMNAMLEIYNGTEEKQVFEKDMLFATLE
TSVRNIDLPDNKSFLLTDTVGFVSKLPHHLVKAFRSTLEEVAEADLLIHVVDYANPNYEQLIDITNETLKKIGVENIPTI
YAYNKSDMVDVEIPKVQEDRVYLSAKKHVGIKELVEMIRSHIYKEYTKCEMLIPYDQGQVVSYFNTHAHVLSTSYENEGT
KLEVECKTSDYEKYKRFAI

Sequences:

>Translated_419_residues
MEELLQRAVLVGVNLGNEDDFAYSMEELTNLAEACDVEVIGQVTQNLQRVNPSHYIGKGKIEEVAAYVNEVGANMVIFND
ELSPSQIRNLEADLDCKVIDRTILILDIFAQRAKTKEAQLQVEVAHLQYMMPRLIGLRESLGRQSGGVGTKNKGVGEKKL
ELDRRKIEEQISVLNKDLEALVAQRQTQRKQRKKNEIPVVALVGYTNAGKSTTMNAMLEIYNGTEEKQVFEKDMLFATLE
TSVRNIDLPDNKSFLLTDTVGFVSKLPHHLVKAFRSTLEEVAEADLLIHVVDYANPNYEQLIDITNETLKKIGVENIPTI
YAYNKSDMVDVEIPKVQEDRVYLSAKKHVGIKELVEMIRSHIYKEYTKCEMLIPYDQGQVVSYFNTHAHVLSTSYENEGT
KLEVECKTSDYEKYKRFAI
>Mature_419_residues
MEELLQRAVLVGVNLGNEDDFAYSMEELTNLAEACDVEVIGQVTQNLQRVNPSHYIGKGKIEEVAAYVNEVGANMVIFND
ELSPSQIRNLEADLDCKVIDRTILILDIFAQRAKTKEAQLQVEVAHLQYMMPRLIGLRESLGRQSGGVGTKNKGVGEKKL
ELDRRKIEEQISVLNKDLEALVAQRQTQRKQRKKNEIPVVALVGYTNAGKSTTMNAMLEIYNGTEEKQVFEKDMLFATLE
TSVRNIDLPDNKSFLLTDTVGFVSKLPHHLVKAFRSTLEEVAEADLLIHVVDYANPNYEQLIDITNETLKKIGVENIPTI
YAYNKSDMVDVEIPKVQEDRVYLSAKKHVGIKELVEMIRSHIYKEYTKCEMLIPYDQGQVVSYFNTHAHVLSTSYENEGT
KLEVECKTSDYEKYKRFAI

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=207, Percent_Identity=34.2995169082126, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124267, Length=207, Percent_Identity=34.2995169082126, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124171, Length=207, Percent_Identity=34.2995169082126, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310124169, Length=207, Percent_Identity=34.2995169082126, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI310133118, Length=230, Percent_Identity=33.0434782608696, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI310133116, Length=215, Percent_Identity=33.953488372093, Blast_Score=119, Evalue=7e-27,
Organism=Escherichia coli, GI1790615, Length=415, Percent_Identity=37.8313253012048, Blast_Score=280, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=299, Percent_Identity=32.1070234113712, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24650079, Length=361, Percent_Identity=28.808864265928, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47601; Mature: 47601

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELLQRAVLVGVNLGNEDDFAYSMEELTNLAEACDVEVIGQVTQNLQRVNPSHYIGKGK
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCH
IEEVAAYVNEVGANMVIFNDELSPSQIRNLEADLDCKVIDRTILILDIFAQRAKTKEAQL
HHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
QVEVAHLQYMMPRLIGLRESLGRQSGGVGTKNKGVGEKKLELDRRKIEEQISVLNKDLEA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVAQRQTQRKQRKKNEIPVVALVGYTNAGKSTTMNAMLEIYNGTEEKQVFEKDMLFATLE
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TSVRNIDLPDNKSFLLTDTVGFVSKLPHHLVKAFRSTLEEVAEADLLIHVVDYANPNYEQ
HHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHH
LIDITNETLKKIGVENIPTIYAYNKSDMVDVEIPKVQEDRVYLSAKKHVGIKELVEMIRS
HHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCEEEEHHHCCCHHHHHHHHHH
HIYKEYTKCEMLIPYDQGQVVSYFNTHAHVLSTSYENEGTKLEVECKTSDYEKYKRFAI
HHHHHHHHCEEEEECCCCCEEEHHCCHHHHEECCCCCCCCEEEEEECCCCHHHHHHCCC
>Mature Secondary Structure
MEELLQRAVLVGVNLGNEDDFAYSMEELTNLAEACDVEVIGQVTQNLQRVNPSHYIGKGK
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCH
IEEVAAYVNEVGANMVIFNDELSPSQIRNLEADLDCKVIDRTILILDIFAQRAKTKEAQL
HHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
QVEVAHLQYMMPRLIGLRESLGRQSGGVGTKNKGVGEKKLELDRRKIEEQISVLNKDLEA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVAQRQTQRKQRKKNEIPVVALVGYTNAGKSTTMNAMLEIYNGTEEKQVFEKDMLFATLE
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
TSVRNIDLPDNKSFLLTDTVGFVSKLPHHLVKAFRSTLEEVAEADLLIHVVDYANPNYEQ
HHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHH
LIDITNETLKKIGVENIPTIYAYNKSDMVDVEIPKVQEDRVYLSAKKHVGIKELVEMIRS
HHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCEEEEHHHCCCHHHHHHHHHH
HIYKEYTKCEMLIPYDQGQVVSYFNTHAHVLSTSYENEGTKLEVECKTSDYEKYKRFAI
HHHHHHHHCEEEEECCCCCEEEHHCCHHHHEECCCCCCCCEEEEEECCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]