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The map label for this gene is 222095417

Identifier: 222095417

GI number: 222095417

Start: 1726121

End: 1727380

Strand: Direct

Name: 222095417

Synonym: BCQ_1757

Alternate gene names: NA

Gene position: 1726121-1727380 (Clockwise)

Preceding gene: 222095416

Following gene: 222095418

Centisome position: 33.1

GC content: 36.67

Gene sequence:

>1260_bases
ATGAGGGTAGAAGTATGGGGAGGAGCGGGAGAATACGGTCGCTCCTGCTACTTCGTAAAAAATAAAGAGACAAAAATATT
ATTTGATTGTGGTATTAATCGGTCATATAAGGATAGTTATCCAAAAATAGAACGAGAAGTTGTACCGTTTTTAGATGCAG
TATTTTTGTCACATATTCATGAAGATCATACGATGGGCTTACCTTTATTAGCGAAGTATGGATATAAGAAAAAAATATGG
ACAACTCGTTATACGAAGGAGCAACTCCCAGCTTACTATGAAAAATGGAGAAACTACAATTTGGCGCAAGGATGGCATGT
ACCTTATACCGACCAAAATGTGAAAGATTTAAATTATGTATATATTGATGAGATTAGCAATCCGAATGAATGGGTACAGA
TTACTCCTACATTGCGTTTTCAATGGGGGTATAGTGGGCATGTATTAGGAGCTGTTTGGTTTTTAGTGGATATGAGTCAT
ACATATGTATTCTATTCTGGCGATTACTCAGCAGAGTCTAACATATTGCGAGCTAATTTACCTGAGAAGTTGCACGGCGA
TATAAAAGTCGCAATCGTAGATGCCGCTTATCATACTGATGATGTTTCGCAACATGAACGAATAAACGAACTATGTACAG
AAATTGAACGCGCCGCCGGGAATAAAGGGATAACATTACTACCATTGCCCCCCCTTGGTAGGGCGCAAGATATCGTATTG
TATTTATATAAAAAATATAAAGAACTCCCTATTATAGTAGATCAAGAAATTTTGGATGGATTTCAACAGATGTTCGCATA
TAAAGATTGGATCAAAAATAATGAAGAACTTGAAGAGCTAATGGAGAGTTTAAAAAGAAACATAATAGTTATGGATGATG
ACAGCGGTACGCAACATAGTTATGGAATAGTTGTAATGAGTGATGCGAATATGCAAACGAAGCGAGCGCAGTTATATTAT
GAACAAGTTCGGCATGACGAACGAAATTCTATTATCTTTACTGGACATATTGCGAAAGGGAGTTTTGCAGAAAAAGTTTT
GAAGGAACGTGTAGGTAAAGAATGTAGGGTGAAGAGAGTTCCATATAAAGTTCACCAAAGTATAAGAGATGTGAAAGAGA
TGTTAAATACATTATCACCAGAACATACGGTGTTAGTACACGCTTTGAAAGAGGATACGGATCGATTACAGAAAAAGCTT
AGCACCGCAGGGTATGAAAATGTATATTCACTTACTATGGAACGAATAGAAGTCATTTGA

Upstream 100 bases:

>100_bases
TATCTATTGGAATGGCGATGGCTGTCGTTTCAGTTGGACTTACAACACTATGTTTATTACTTCTGCAGCATATGGAGCAC
AAACGAAAAGGGGTAGCATG

Downstream 100 bases:

>100_bases
AATGTAAAGGGGATAGGTATATGAAAAGCGTATTTGTATTCGTAAGTATTTTCTTTTGTTGTTTCCTTTATAACGTTAAG
GAAGGATTTGCCGCTAGTCC

Product: metallo-beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYKDSYPKIEREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPAYYEKWRNYNLAQGWHVPYTDQNVKDLNYVYIDEISNPNEWVQITPTLRFQWGYSGHVLGAVWFLVDMSH
TYVFYSGDYSAESNILRANLPEKLHGDIKVAIVDAAYHTDDVSQHERINELCTEIERAAGNKGITLLPLPPLGRAQDIVL
YLYKKYKELPIIVDQEILDGFQQMFAYKDWIKNNEELEELMESLKRNIIVMDDDSGTQHSYGIVVMSDANMQTKRAQLYY
EQVRHDERNSIIFTGHIAKGSFAEKVLKERVGKECRVKRVPYKVHQSIRDVKEMLNTLSPEHTVLVHALKEDTDRLQKKL
STAGYENVYSLTMERIEVI

Sequences:

>Translated_419_residues
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYKDSYPKIEREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPAYYEKWRNYNLAQGWHVPYTDQNVKDLNYVYIDEISNPNEWVQITPTLRFQWGYSGHVLGAVWFLVDMSH
TYVFYSGDYSAESNILRANLPEKLHGDIKVAIVDAAYHTDDVSQHERINELCTEIERAAGNKGITLLPLPPLGRAQDIVL
YLYKKYKELPIIVDQEILDGFQQMFAYKDWIKNNEELEELMESLKRNIIVMDDDSGTQHSYGIVVMSDANMQTKRAQLYY
EQVRHDERNSIIFTGHIAKGSFAEKVLKERVGKECRVKRVPYKVHQSIRDVKEMLNTLSPEHTVLVHALKEDTDRLQKKL
STAGYENVYSLTMERIEVI
>Mature_419_residues
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYKDSYPKIEREVVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPAYYEKWRNYNLAQGWHVPYTDQNVKDLNYVYIDEISNPNEWVQITPTLRFQWGYSGHVLGAVWFLVDMSH
TYVFYSGDYSAESNILRANLPEKLHGDIKVAIVDAAYHTDDVSQHERINELCTEIERAAGNKGITLLPLPPLGRAQDIVL
YLYKKYKELPIIVDQEILDGFQQMFAYKDWIKNNEELEELMESLKRNIIVMDDDSGTQHSYGIVVMSDANMQTKRAQLYY
EQVRHDERNSIIFTGHIAKGSFAEKVLKERVGKECRVKRVPYKVHQSIRDVKEMLNTLSPEHTVLVHALKEDTDRLQKKL
STAGYENVYSLTMERIEVI

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7706427, Length=434, Percent_Identity=25.5760368663594, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI33300633, Length=439, Percent_Identity=22.7790432801822, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI32566029, Length=439, Percent_Identity=22.3234624145786, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32564696, Length=434, Percent_Identity=21.889400921659, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648013, Length=431, Percent_Identity=25.2900232018561, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21358523, Length=433, Percent_Identity=23.094688221709, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 48873; Mature: 48873

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYKDSYPKIEREVVPFLDAVFLSHIH
CEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
EDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNLAQGWHVPYTDQNVKDLNYV
CCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
YIDEISNPNEWVQITPTLRFQWGYSGHVLGAVWFLVDMSHTYVFYSGDYSAESNILRANL
EEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCC
PEKLHGDIKVAIVDAAYHTDDVSQHERINELCTEIERAAGNKGITLLPLPPLGRAQDIVL
CHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
YLYKKYKELPIIVDQEILDGFQQMFAYKDWIKNNEELEELMESLKRNIIVMDDDSGTQHS
HHHHHHCCCCEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCCEE
YGIVVMSDANMQTKRAQLYYEQVRHDERNSIIFTGHIAKGSFAEKVLKERVGKECRVKRV
EEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEECC
PYKVHQSIRDVKEMLNTLSPEHTVLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI
CHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVEVWGGAGEYGRSCYFVKNKETKILFDCGINRSYKDSYPKIEREVVPFLDAVFLSHIH
CEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
EDHTMGLPLLAKYGYKKKIWTTRYTKEQLPAYYEKWRNYNLAQGWHVPYTDQNVKDLNYV
CCCCCCCHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEE
YIDEISNPNEWVQITPTLRFQWGYSGHVLGAVWFLVDMSHTYVFYSGDYSAESNILRANL
EEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCC
PEKLHGDIKVAIVDAAYHTDDVSQHERINELCTEIERAAGNKGITLLPLPPLGRAQDIVL
CHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHH
YLYKKYKELPIIVDQEILDGFQQMFAYKDWIKNNEELEELMESLKRNIIVMDDDSGTQHS
HHHHHHCCCCEEECHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEECCCCCCEE
YGIVVMSDANMQTKRAQLYYEQVRHDERNSIIFTGHIAKGSFAEKVLKERVGKECRVKRV
EEEEEEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEECC
PYKVHQSIRDVKEMLNTLSPEHTVLVHALKEDTDRLQKKLSTAGYENVYSLTMERIEVI
CHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]