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The map label for this gene is cheC [H]

Identifier: 222095355

GI number: 222095355

Start: 1668926

End: 1670566

Strand: Direct

Name: cheC [H]

Synonym: BCQ_1695

Alternate gene names: 222095355

Gene position: 1668926-1670566 (Clockwise)

Preceding gene: 222095354

Following gene: 222095356

Centisome position: 32.01

GC content: 37.17

Gene sequence:

>1641_bases
ATGCCTGAGCAACACACAAAAGGGGATACGAGCACAATTGTGCTAGAAAAAGAAAAGGAGCTTTTAACGCCTCAAGAATG
TGATATTCTTGGCGAAATTGCAAATATATCATTTGGCTCTGCTTCGACAGTATTATCAACGATTTTAAATAGGCAAGTAA
GTATAACTGCTCCTCATGTAGAGTTAGTGGATTTATACGATACAAGCGATGTTGAGGTTCCTCATGTTGTATTAAATATT
CATTTTACAAAAGGATTAGATATGGAAAATCTACTTGTCCTTCAGCAAGATGTTGCTTTATCTATTGCTGATTTAATGAT
GATGGGGACAGGTGAAGTGGAAGAGGGAAAAGAACTTGGCGAATTAGAGCTAAGTGCTGTACAAGAAGCGATGAACCAGA
TGATGGGATTCGCAGCGACGTCTATGTCGGAATTCTTCCAAGATACAGTAGACATGTCACCGCCGACAATTAAAGTTGTA
AAGTTATTAGAAGAGATGGAGAAAATCTCTGGAATAACTGGAAATAACACGATTGTGAAAGTGTCGTTTGACCTTAAAAT
AGATAATCTTGTAAACTCTAAACTTGTACAAATTGTTTCAGTTGAACATGCGAAACAAATGATAAATAAATTACTACAAT
TATCTGGTGGCGTAGAAGAGCAAGACGAGCCAGCAGAAGTAGCGGAAGCCGAGATTGTAGAAGAACATGTTAAAAAAGAG
CAGTTAACGCAAGAGGAGAAAGATGTACTTGGGGAAATTGCCAACATTTCCATCGGTTCAGCCTCAACGGTATTATCAAC
GCTTTTAAATCAGCCGGTTACGATTAGTACACCCAATGTAGAAGCGATTAATGTGCGTCATTATGACGGTGTACCGGTTC
CCTTTGTGATTTTAAATGTCGATTTTGTTGAAGGTTTAAAGAATGAGAACGTATTCGTATTTACGAAAGATGTTGCTTTG
ACAATGGTAGATTTAATGATGATGGGAACAGGGGAGATTGATCCAGAGAAAGAGCTTAGTGAATTAGAGCTGAGCGGTAT
TAAAGAAATCATGAACCAAATGATGGGGCATGCGGCAACAGCGATGTCAGAAATGTTTAAAGAGAAGATGGACATGACGC
CGCCAGACGTCAAATTTGTCACGTTAAAAGAAGAAATGGAATATTTGGGAGAGTCAATGGAAGTGGATGAACTCGTTCAA
ATTACGTTCAACCTTGAAATTGGCGACTTGCTTCAATCGAAAATGTATCAAATTTTACCGATTTCAGAAGCGAAAGAAAT
GGTAAGACGACTGCTATATCCAATGGTGGAAGCAGAAGAAGAGGTTGCAGAGGAAGAAATGGAAGAAGAGGTTGTAGAAC
CTGTTGTACAACCTATTGAATTTAAAGAAGTGAAACAAATTGAGCCAGTGTATATGGATACATCTATTCTACAAAATGTA
GAAATGAATGTGAAATTTGTATTTGGAAGTACAGTGAAAACGATTCAAGATATATTAAGTTTACAAGAAAATGAAGCCGT
TGTATTAGATGAAGATATTGATGAACCAATTCGAATTTATGTAAATGATGTATTGGTGGCGTATGGTGAACTTGTAAATG
TAGATGGATTTTTCGGAGTAAAAGTGACAAAATCACTATAA

Upstream 100 bases:

>100_bases
ACAGGAAATAAATACATGTTCACGATTTACGTAATAAATTTGTTAAAATGTAATGAGTGTATTCATTTAATAGAAAAACA
AAAATGAGGAGGCAGGGAAA

Downstream 100 bases:

>100_bases
GGCGTTGAAATAGTAGATGAAAAGCGTAAAGTTTTTTCTAATTTGCTGGCTATGCATACATGTGTGCTTGCTCTTCCCAC
TGCAAAGTCAGGCGGAAGAG

Product: flagellar motor switch protein

Products: NA

Alternate protein names: CheY-P phosphatase FliY [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MPEQHTKGDTSTIVLEKEKELLTPQECDILGEIANISFGSASTVLSTILNRQVSITAPHVELVDLYDTSDVEVPHVVLNI
HFTKGLDMENLLVLQQDVALSIADLMMMGTGEVEEGKELGELELSAVQEAMNQMMGFAATSMSEFFQDTVDMSPPTIKVV
KLLEEMEKISGITGNNTIVKVSFDLKIDNLVNSKLVQIVSVEHAKQMINKLLQLSGGVEEQDEPAEVAEAEIVEEHVKKE
QLTQEEKDVLGEIANISIGSASTVLSTLLNQPVTISTPNVEAINVRHYDGVPVPFVILNVDFVEGLKNENVFVFTKDVAL
TMVDLMMMGTGEIDPEKELSELELSGIKEIMNQMMGHAATAMSEMFKEKMDMTPPDVKFVTLKEEMEYLGESMEVDELVQ
ITFNLEIGDLLQSKMYQILPISEAKEMVRRLLYPMVEAEEEVAEEEMEEEVVEPVVQPIEFKEVKQIEPVYMDTSILQNV
EMNVKFVFGSTVKTIQDILSLQENEAVVLDEDIDEPIRIYVNDVLVAYGELVNVDGFFGVKVTKSL

Sequences:

>Translated_546_residues
MPEQHTKGDTSTIVLEKEKELLTPQECDILGEIANISFGSASTVLSTILNRQVSITAPHVELVDLYDTSDVEVPHVVLNI
HFTKGLDMENLLVLQQDVALSIADLMMMGTGEVEEGKELGELELSAVQEAMNQMMGFAATSMSEFFQDTVDMSPPTIKVV
KLLEEMEKISGITGNNTIVKVSFDLKIDNLVNSKLVQIVSVEHAKQMINKLLQLSGGVEEQDEPAEVAEAEIVEEHVKKE
QLTQEEKDVLGEIANISIGSASTVLSTLLNQPVTISTPNVEAINVRHYDGVPVPFVILNVDFVEGLKNENVFVFTKDVAL
TMVDLMMMGTGEIDPEKELSELELSGIKEIMNQMMGHAATAMSEMFKEKMDMTPPDVKFVTLKEEMEYLGESMEVDELVQ
ITFNLEIGDLLQSKMYQILPISEAKEMVRRLLYPMVEAEEEVAEEEMEEEVVEPVVQPIEFKEVKQIEPVYMDTSILQNV
EMNVKFVFGSTVKTIQDILSLQENEAVVLDEDIDEPIRIYVNDVLVAYGELVNVDGFFGVKVTKSL
>Mature_545_residues
PEQHTKGDTSTIVLEKEKELLTPQECDILGEIANISFGSASTVLSTILNRQVSITAPHVELVDLYDTSDVEVPHVVLNIH
FTKGLDMENLLVLQQDVALSIADLMMMGTGEVEEGKELGELELSAVQEAMNQMMGFAATSMSEFFQDTVDMSPPTIKVVK
LLEEMEKISGITGNNTIVKVSFDLKIDNLVNSKLVQIVSVEHAKQMINKLLQLSGGVEEQDEPAEVAEAEIVEEHVKKEQ
LTQEEKDVLGEIANISIGSASTVLSTLLNQPVTISTPNVEAINVRHYDGVPVPFVILNVDFVEGLKNENVFVFTKDVALT
MVDLMMMGTGEIDPEKELSELELSGIKEIMNQMMGHAATAMSEMFKEKMDMTPPDVKFVTLKEEMEYLGESMEVDELVQI
TFNLEIGDLLQSKMYQILPISEAKEMVRRLLYPMVEAEEEVAEEEMEEEVVEPVVQPIEFKEVKQIEPVYMDTSILQNVE
MNVKFVFGSTVKTIQDILSLQENEAVVLDEDIDEPIRIYVNDVLVAYGELVNVDGFFGVKVTKSL

Specific function: Component of the flagellar switch. Binds CheY-P and increases its hydrolysis rate in vitro. May function constitutively to remove CheY-P around the flagellar switch to maintain an optimal level of CheY-P whereas CheC may function after addition of an attr

COG id: COG1776

COG function: function code NT; Chemotaxis protein CheC, inhibitor of MCP methylation

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=The switch is localized at the base of the flagellar motor, in or near the C-ring, attached to the MS-ring (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliN/MopA/SpaO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007597
- InterPro:   IPR012826
- InterPro:   IPR001172
- InterPro:   IPR001543 [H]

Pfam domain/function: PF04509 CheC; PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 60836; Mature: 60705

Theoretical pI: Translated: 3.94; Mature: 3.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEQHTKGDTSTIVLEKEKELLTPQECDILGEIANISFGSASTVLSTILNRQVSITAPHV
CCCCCCCCCCEEEEEECCHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCE
ELVDLYDTSDVEVPHVVLNIHFTKGLDMENLLVLQQDVALSIADLMMMGTGEVEEGKELG
EEEEEECCCCCCCCEEEEEEEEECCCCHHHHHEEHHHHHHHHHHHHHHCCCCCCCCHHHH
ELELSAVQEAMNQMMGFAATSMSEFFQDTVDMSPPTIKVVKLLEEMEKISGITGNNTIVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
VSFDLKIDNLVNSKLVQIVSVEHAKQMINKLLQLSGGVEEQDEPAEVAEAEIVEEHVKKE
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
QLTQEEKDVLGEIANISIGSASTVLSTLLNQPVTISTPNVEAINVRHYDGVPVPFVILNV
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCCCEEEEEE
DFVEGLKNENVFVFTKDVALTMVDLMMMGTGEIDPEKELSELELSGIKEIMNQMMGHAAT
HHHHCCCCCCEEEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMSEMFKEKMDMTPPDVKFVTLKEEMEYLGESMEVDELVQITFNLEIGDLLQSKMYQILP
HHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCC
ISEAKEMVRRLLYPMVEAEEEVAEEEMEEEVVEPVVQPIEFKEVKQIEPVYMDTSILQNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEECHHHHHCC
EMNVKFVFGSTVKTIQDILSLQENEAVVLDEDIDEPIRIYVNDVLVAYGELVNVDGFFGV
CCEEEEEECCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
KVTKSL
EEECCC
>Mature Secondary Structure 
PEQHTKGDTSTIVLEKEKELLTPQECDILGEIANISFGSASTVLSTILNRQVSITAPHV
CCCCCCCCCEEEEEECCHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCE
ELVDLYDTSDVEVPHVVLNIHFTKGLDMENLLVLQQDVALSIADLMMMGTGEVEEGKELG
EEEEEECCCCCCCCEEEEEEEEECCCCHHHHHEEHHHHHHHHHHHHHHCCCCCCCCHHHH
ELELSAVQEAMNQMMGFAATSMSEFFQDTVDMSPPTIKVVKLLEEMEKISGITGNNTIVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
VSFDLKIDNLVNSKLVQIVSVEHAKQMINKLLQLSGGVEEQDEPAEVAEAEIVEEHVKKE
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
QLTQEEKDVLGEIANISIGSASTVLSTLLNQPVTISTPNVEAINVRHYDGVPVPFVILNV
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCEEEEEEECCCCCCCEEEEEE
DFVEGLKNENVFVFTKDVALTMVDLMMMGTGEIDPEKELSELELSGIKEIMNQMMGHAAT
HHHHCCCCCCEEEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMSEMFKEKMDMTPPDVKFVTLKEEMEYLGESMEVDELVQITFNLEIGDLLQSKMYQILP
HHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCC
ISEAKEMVRRLLYPMVEAEEEVAEEEMEEEVVEPVVQPIEFKEVKQIEPVYMDTSILQNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEECHHHHHCC
EMNVKFVFGSTVKTIQDILSLQENEAVVLDEDIDEPIRIYVNDVLVAYGELVNVDGFFGV
CCEEEEEECCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
KVTKSL
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1447979; 9384377; 1898932 [H]