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The map label for this gene is ywcA [H]

Identifier: 222095327

GI number: 222095327

Start: 1645085

End: 1646476

Strand: Direct

Name: ywcA [H]

Synonym: BCQ_1667

Alternate gene names: 222095327

Gene position: 1645085-1646476 (Clockwise)

Preceding gene: 222095326

Following gene: 222095328

Centisome position: 31.55

GC content: 39.51

Gene sequence:

>1392_bases
ATGTCTGCTGCGTCTTTTCTTGGTATAGCTGGAGCGATCGCATTAACTGGGTTTGATGGTTTCTTTTATAGTATCGGCTT
TTTAGTTGCTTATTTAGTTGTTCTATACCTTGTCGCAGAACCGCTAAGGAATTTAGGGAAGTACACGTTAGCGGATATGA
TTGCGGCGCGTTTTGACGCGAAAAAAGTTCGCGGAGTTGCAGCGCTTAATACGATGACGATTTCAATTTTTTATATGATT
GCACAATTAGTTGGGGCGGGTGCACTTATTAAGTTATTATTAGGGATCGAATATACAACATCCGTTTTAATTGTTGGTAC
ATTAATGACAGTGTACGTTATTTTTGGCGGAATGACCGCGACGAGCTGGGTGCAAATTGTTAAGGCTGTATTACTTATGG
CCGGTACATTTATTATTTCTGTTATCGTTTTCGCAAAATTTAATTTTAGTGTGACGGAAATGTTTGCTCAAATGAAAACA
GCAACTCCATTAAAAGATTCGTTTTTAAATCCAGGAGTAAAGTATAAAGATGGTCTTGATACACTATCTTTAAATTTAGG
ACTAGTCCTTGGTACGGCAGGATTACCACACATTCTTGTTCGCTTTTTTACAGTACGTGATGCAAAAACAGCACGTCAAT
CTGTCGTATACGCTACGTGGTTAATTGGCGCATTTTATATTATGACAATTTTCTTAGGATTTGGGGCAGCGGCGTTTGTA
GGGAATGAGGCGATTATGAAAGCAAACCCTGCTGGTAATATGGCAGCACCTTTATTAGCGAAAGCATTGGGCGGAGATTT
CTTATTTGCTTTCGTATCAGCAATTGCTTTTGCAACGATTTTAGCTGTAGTGGCAGGCCTTGTATTAACAGCAGCATCCG
CATTCGCACATGATTTTTATAATGAAATTATCCGCAAGGGGAAATCAACGGAAAAAGAGCAAGTATCCATGGCTCGTTAT
GCGTCTATTGGAGTAGCGGTATTGTCTATTATACTAGCGTTATTTGCTCAAACATTGAACGTAGCATTTTTAGTTTCGTT
AGCATTTGCAGTTGCAGCGAGTGCAAACTTGCCAGTTATATTATTCACAATATATTGGAAGCGCTTCAATACAACAGGTG
CCATCTCTGGTATGATTGCTGGTCTTGTATCAGCTATTGTTCTTGTAGCGTTAAGCCCAAATGTATGGAACCCTGTAGCT
GGAAAAGCTATATTTGTCGGGGAAGCGATATTCCCATATACGACACCCGGAATTATTTCGATTCCGCTTGGATTTCTTGC
AGCGTATTTAGGAACTGTTTTATCTAGTAAGAAAGAAGATGCAGCGAAATTTGATGAAATTCTCGTGAAATCTAATACTG
GGCATGGTATTAGTGACGCGTCTTCGCATTAA

Upstream 100 bases:

>100_bases
CTATTTTGCATCGAAAAAAACGAAAAATGCGAGTGAGTTTTATACAGCTGGAGGGGGATTAACTGGTTGGCAAAATGGTC
TGGCCATTGCGGGAGATTAT

Downstream 100 bases:

>100_bases
AAAAGAGGAGCTTTTCGATAGATAAGAAAAGCTCCTTTTTCTTTTGTCATTTTCTTGTAAATAATACTGCTTTGTAAGTA
GGATTTGTCTTAATTTTGTG

Product: sodium/solute symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSAASFLGIAGAIALTGFDGFFYSIGFLVAYLVVLYLVAEPLRNLGKYTLADMIAARFDAKKVRGVAALNTMTISIFYMI
AQLVGAGALIKLLLGIEYTTSVLIVGTLMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFNFSVTEMFAQMKT
ATPLKDSFLNPGVKYKDGLDTLSLNLGLVLGTAGLPHILVRFFTVRDAKTARQSVVYATWLIGAFYIMTIFLGFGAAAFV
GNEAIMKANPAGNMAAPLLAKALGGDFLFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRKGKSTEKEQVSMARY
ASIGVAVLSIILALFAQTLNVAFLVSLAFAVAASANLPVILFTIYWKRFNTTGAISGMIAGLVSAIVLVALSPNVWNPVA
GKAIFVGEAIFPYTTPGIISIPLGFLAAYLGTVLSSKKEDAAKFDEILVKSNTGHGISDASSH

Sequences:

>Translated_463_residues
MSAASFLGIAGAIALTGFDGFFYSIGFLVAYLVVLYLVAEPLRNLGKYTLADMIAARFDAKKVRGVAALNTMTISIFYMI
AQLVGAGALIKLLLGIEYTTSVLIVGTLMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFNFSVTEMFAQMKT
ATPLKDSFLNPGVKYKDGLDTLSLNLGLVLGTAGLPHILVRFFTVRDAKTARQSVVYATWLIGAFYIMTIFLGFGAAAFV
GNEAIMKANPAGNMAAPLLAKALGGDFLFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRKGKSTEKEQVSMARY
ASIGVAVLSIILALFAQTLNVAFLVSLAFAVAASANLPVILFTIYWKRFNTTGAISGMIAGLVSAIVLVALSPNVWNPVA
GKAIFVGEAIFPYTTPGIISIPLGFLAAYLGTVLSSKKEDAAKFDEILVKSNTGHGISDASSH
>Mature_462_residues
SAASFLGIAGAIALTGFDGFFYSIGFLVAYLVVLYLVAEPLRNLGKYTLADMIAARFDAKKVRGVAALNTMTISIFYMIA
QLVGAGALIKLLLGIEYTTSVLIVGTLMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFNFSVTEMFAQMKTA
TPLKDSFLNPGVKYKDGLDTLSLNLGLVLGTAGLPHILVRFFTVRDAKTARQSVVYATWLIGAFYIMTIFLGFGAAAFVG
NEAIMKANPAGNMAAPLLAKALGGDFLFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRKGKSTEKEQVSMARYA
SIGVAVLSIILALFAQTLNVAFLVSLAFAVAASANLPVILFTIYWKRFNTTGAISGMIAGLVSAIVLVALSPNVWNPVAG
KAIFVGEAIFPYTTPGIISIPLGFLAAYLGTVLSSKKEDAAKFDEILVKSNTGHGISDASSH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=415, Percent_Identity=25.0602409638554, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1790503, Length=472, Percent_Identity=44.7033898305085, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1787251, Length=408, Percent_Identity=27.9411764705882, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082237, Length=408, Percent_Identity=24.2647058823529, Blast_Score=77, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648033, Length=390, Percent_Identity=24.6153846153846, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356865, Length=390, Percent_Identity=24.6153846153846, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 48938; Mature: 48806

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAASFLGIAGAIALTGFDGFFYSIGFLVAYLVVLYLVAEPLRNLGKYTLADMIAARFDA
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]