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The map label for this gene is dnaB [H]

Identifier: 222094683

GI number: 222094683

Start: 1021529

End: 1022596

Strand: Direct

Name: dnaB [H]

Synonym: BCQ_1021

Alternate gene names: 222094683

Gene position: 1021529-1022596 (Clockwise)

Preceding gene: 222094682

Following gene: 222094685

Centisome position: 19.59

GC content: 43.54

Gene sequence:

>1068_bases
ATGGAGTATTTTATAGGGTTAATGGATGGTGTGCCTACTACTAGCAACTTCTCTTATTATGAGGGGCTTGTTCGAGGTGC
CTGGAAAATGTATCAGGCGGGTGTTCTTGGGCACAAGATGGGAGAGCGTCTTATTGCAGAGAAGAGTGAGAAAATTATTG
GTGAGACGATTACGGCACTTTGTGAGTTAGAGGAGAAGGACTGTGTATGTGAGTTTGATTTGAAGGATGCGCTAGTTGAT
TTATATGAAGAGCTTCATCAAGATGCGAAAGAGATTACTGGTATTGAGACGGGTTATACATCGCTAAATAAAATGACGTG
CGGATTGCAGGAAGGAGATTTTGTTGTTCTCGGTGCTCGTCCTTCGATGGGGAAGACAGCGTTTGCGCTAAATGTTGGAC
TGCATGCGGCGAAGTCTGGCGCGGCGGTTGGGTTGTTTTCGTTAGAGATGAGTAGTAAGCAATTATTGAAAAGGGTAGCT
TCTTGCGTAGGTGAAGTGTCAGGAGGTAGGCTGAAAAATCCGAAGCATCGTTTTGCGATGGAAGACTGGGAAAGGATGAG
TAAGGCGTTTGCGGAGATTGGTGAGTTACCTCTTGAGATTTACGACAATGCAGGGGTTACGGTGCAAGATATTTGGATGC
AAACTCGTAAGTTAAAGAGGAAGCACGGTGATAAAAAGGTTTTAATTATTGTAGATTATTTGCAGCTTATTACGGGCGAT
CCGAAGCATAAGGGCAATCGTTTTCAAGAGATTAGTGAGATTTCTCGTAAACTTAAGTTATTAGCACGTGAGTTAAATGT
TTGTGTAGTAGCATTGTCGCAATTGTCTCGTTCTGTAGAGTCGCGTCAAGATAAGCGTCCTCTTTTATCTGATTTAAGAG
AGACAGGGCAAATTGAGCAAGATGCGGATGTCATTATGCTTATGTATCGCGAAGATTATTACGATAAGGAAACGAAGCAG
AAAGAGATGACGGAGATTCATGTGGCGAAGCATCGGAATGGACCTGTGGGGAGTTTTAAGCTGCGGTTTATGAAGGAGTT
TGGGCGGTTTGTGGAGGGGAAGAAATAG

Upstream 100 bases:

>100_bases
ATTTCAGTTAATGCGAAAGATGGAAGATGAGGGACAGCCGATTGATCTTGTGACGTTCACTTCTAGAGTGGATCCGAAGT
TTTTGAAGGGGATCGGGGGA

Downstream 100 bases:

>100_bases
TTAGAGAGGAAGTTTATGTTAGGAAAAAGTTACGTATGATTTTAGTGGGATTCAAATTGTAAAAAGACACCTTAAGGTGC
CTTTTTACAATTTAAATCCT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MEYFIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVD
LYEELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRVA
SCVGEVSGGRLKNPKHRFAMEDWERMSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKVLIIVDYLQLITGD
PKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETKQ
KEMTEIHVAKHRNGPVGSFKLRFMKEFGRFVEGKK

Sequences:

>Translated_355_residues
MEYFIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVD
LYEELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRVA
SCVGEVSGGRLKNPKHRFAMEDWERMSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKVLIIVDYLQLITGD
PKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETKQ
KEMTEIHVAKHRNGPVGSFKLRFMKEFGRFVEGKK
>Mature_355_residues
MEYFIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITALCELEEKDCVCEFDLKDALVD
LYEELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRVA
SCVGEVSGGRLKNPKHRFAMEDWERMSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKVLIIVDYLQLITGD
PKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDKETKQ
KEMTEIHVAKHRNGPVGSFKLRFMKEFGRFVEGKK

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=365, Percent_Identity=39.1780821917808, Blast_Score=228, Evalue=5e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 40163; Mature: 40163

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYFIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITAL
CCCEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CELEEKDCVCEFDLKDALVDLYEELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGAR
HHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEEEECC
PSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRVASCVGEVSGGRLKNPKHRFAM
CCCCCEEEEEECCHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
EDWERMSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKVLIIVDYLQLITGD
HHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCC
PKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
DADVIMLMYREDYYDKETKQKEMTEIHVAKHRNGPVGSFKLRFMKEFGRFVEGKK
CCCEEEEEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEYFIGLMDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGERLIAEKSEKIIGETITAL
CCCEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CELEEKDCVCEFDLKDALVDLYEELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGAR
HHCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCEEEEECC
PSMGKTAFALNVGLHAAKSGAAVGLFSLEMSSKQLLKRVASCVGEVSGGRLKNPKHRFAM
CCCCCEEEEEECCHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
EDWERMSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKVLIIVDYLQLITGD
HHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCC
PKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
DADVIMLMYREDYYDKETKQKEMTEIHVAKHRNGPVGSFKLRFMKEFGRFVEGKK
CCCEEEEEEHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]