Click here to switch to the map view.

The map label for this gene is mcrB [C]

Identifier: 222094668

GI number: 222094668

Start: 998618

End: 1001155

Strand: Direct

Name: mcrB [C]

Synonym: BCQ_1006

Alternate gene names: 222094668

Gene position: 998618-1001155 (Clockwise)

Preceding gene: 222094667

Following gene: 222094669

Centisome position: 19.15

GC content: 35.19

Gene sequence:

>2538_bases
ATGTTAGAGCAACTTATAATTGAATTGGCTAAAACAACGAAGCAGGTTGAAGATATAAAAGGTGATAAAACTTATTGGAT
TATAAACAAGGATGATAAAGGATTAGATGTTCAAACTAAAACTTCAAGTGGACAATATGCAAAAGAAGAAGAACCATCTG
ATTTTAACGTGAGTTTTGAGCTTCTTAAGAATGCTTGGGGAAAGATTATCGCTATGCGTACGGTAAAGAGTAAAGATTTC
GGACAAGCAGGTGAATGTAATGCTTTCTTGTTAGCCTTCTTTTCACAGCTGCCATTTGTGAATGTAATAGAATCAGGAGC
TATTGCATTTAAAGAATTCCAAACCGATAACCTACCAAGTGAAAAATATGATAAAGTCATACTCTTTTTAGAAGAGATCA
TAAATGGTACATATAATCCAAGTACGTTAAGTGAACAAATGGATGAAAATTTATATAGTAGGAAGTCTCGCGCGCGTCAA
GATTTAAGATTATTGGGCTTTTTGAATGAATCTCATGAAATGAATCAGCTTTTATTAAATGAATATGTTCAATCGGAAGA
TAAGAATGCTTATATAGCACAGCTAGTTTTAAGGCAGGAATATTTCCGTCATGCTTTATTTGTTCTTGGATTGTTAGAGA
AGTATTCAAAGGATGAAAAGAAAGAAGCTTTAGTAGGTTTTGGAATGACGATTGTTCGAAATTCTTTAGGTGATAATCTA
ATGGTTGAATCGGTAGCGAAGAGGCGTACGGGTAACTTACTAGATTGGCTTGAACAAGTAGGGCTAATTAATGGTGAATG
GATTCCTGTTGAACAATATGCAAAAGACGATGGAGAAAAGGGCGGTAGTATGGACAGTAATTTGCGTGAAAAGTTTTTAA
CGGTTCTGAATGAGTATTTACAGGCAAGAACAGAAAGATTTGCGGGGCATAAAATGGGATCGTTTGTTAGGAATGAAATG
ACAACGGAAATAACGAGATTACCATTTATTGATCATAGTCAGTATGTTGTTACAGGGTCAGTTGGACAAGGGAATTGGGC
TGCTGTTCCATGGCTTGCGATTATGAATAAAGATATTACGACATCTACGCAGAGAGGTTATTATATCGTTTATTTGTTTA
GTGAAGATATGGAGCGATTATATTTAACGCTGGCGCAAGGTGTGACAGAAACAACTAAAGAAGAGATGCAAAAAATTAAA
GAAGAGATCCGTGAACAAATACATATGTCTCAAAAAGTGAAAAAAGATGATGAGATCTTTCTTGGCACGAGTACGAAAGC
AAAGGGATATTCGAATTCAACCGCGGCTTATATTGCATACGATGTTAATAAAATGCCAAGCGAAGCAGAATTAGTGGAAG
ACTTGGAAGAAATGCTTCGCTATTATGAGGGATTCATAGCCTACAAAAAGGAAGGAACGAAGTATGAAATGATTTATGAG
AGGAAAGAAGTGTATTTAGATCAGCAATCAATTATCGACCATGTGTCTTCTTATATTCAAAGTAAAGGTTTCTTTTATGA
GAAAAATGATCTTGTTAATTTCTTCCTTTCGTTAAAGACGAAGCCATTTGTGATTTTATCAGGTATTTCAGGTACAGGGA
AAACGAAAATTGTTCAGTGGTTTGCGGAAAGTTTAGGAGCAACGGAAGAGAATGGACAATTTACACTTATCCCGGTTCGA
CCTGATTGGAGTGATAGCTCTGATTTACTCGGTTATGTGAATCTTCAAGGGGAGTTTCAAGAAAGACCGTTAATTAAAGT
TCTTGAAAACGCAGATGCAAATCCAAATAGGCCGTATTTTGTAGTGTTAGACGAGATGAATTTAGCTCGAGTGGAATACT
ACTTTAGTGACTTTTTAAGTGTAATTGAAAGTCGTAAATGGAAAGATGGAAAAATTGTTACGTCACCTGTTCTTCCTGAG
TCAATTGCGAATAAGCATATTACGATTCCATCAAATGTATATATTATCGGAACGGTAAATATGGATGAAACGACACATCC
GTTAAGTAAGAGAGTATTAGATCGTGCGAATACAATTGAGTTTAATACCGTTAACTTAGATTATTTTAATTTCTTAATGG
ATGTAGAGGAGAAGGAAGCTGAAATTGCTTCGAATCGCTCTTTAGAAACCGAGTATCTTCATCTAAAAGAATGTTTTAAA
GACAACGAAGATCTTGTGAGAAATATCTCAACTATTTTAATAGAAATAAATAAAATACTTGAATCAGTTGGAGCTCAAGT
TGGATATCGTATACGAGATGAAATTTGTTTCTATATGGCATACAACGAGCAAGGAAAGTTATTAACGTTTGATGAATCGC
TGGATTATCAAATATATCAAAAGATTTTACCGCGTCTTGCAGGGAGTGATGGAAGAACAGAAGAGGTATTAAAGCAGTTG
TATGTATTATGTGCAAATGAAGAATATGATAGTAGCAATAGTGACGCTTCATATGCTAAGTATCCTCGTTCTGCTAACAA
GCTGTCTCATATGTTAAGGAGGTTCGAGTATGATGGTTTCACCTCTTTCTGGATCTAA

Upstream 100 bases:

>100_bases
AGTAGAGTAGAAAATCATACATTAAATTGTATGATTTTTCTTTTATACATAGTTTGGTAAAATAGTAGTAATTGTAATTA
ATTGTAACGGTGGGATGAAA

Downstream 100 bases:

>100_bases
TGATGAGATAGAATTAGTTAAGATTGAAACAGAGGAGCTATCATTGACGATTAAAGGAAATCCTTATCATGAAAAATATG
AGAGTTTAAAAGAATATCAC

Product: 5-methylcytosine-specific restriction related enzyme

Products: NA

Alternate protein names: GTPase Subunit Of Restriction Endonuclease-Like Protein; 5-Methylcytosine-Specific Restriction ; GTPase Subunit Of Restriction Endonuclease-Like; Site-Specific DNA-Methyltransferase Cytosine-Specific; 5-Methylcytosine-Specific Restriction McrB Related Protein; AAA Family ATPase; Restriction Endonuclease; AAA ATPase; 5-Methylcytosine-Specific Restriction-Like Protein; Chromosome Segregation ATPase-Like Protein; ATPase AAA Family

Number of amino acids: Translated: 845; Mature: 845

Protein sequence:

>845_residues
MLEQLIIELAKTTKQVEDIKGDKTYWIINKDDKGLDVQTKTSSGQYAKEEEPSDFNVSFELLKNAWGKIIAMRTVKSKDF
GQAGECNAFLLAFFSQLPFVNVIESGAIAFKEFQTDNLPSEKYDKVILFLEEIINGTYNPSTLSEQMDENLYSRKSRARQ
DLRLLGFLNESHEMNQLLLNEYVQSEDKNAYIAQLVLRQEYFRHALFVLGLLEKYSKDEKKEALVGFGMTIVRNSLGDNL
MVESVAKRRTGNLLDWLEQVGLINGEWIPVEQYAKDDGEKGGSMDSNLREKFLTVLNEYLQARTERFAGHKMGSFVRNEM
TTEITRLPFIDHSQYVVTGSVGQGNWAAVPWLAIMNKDITTSTQRGYYIVYLFSEDMERLYLTLAQGVTETTKEEMQKIK
EEIREQIHMSQKVKKDDEIFLGTSTKAKGYSNSTAAYIAYDVNKMPSEAELVEDLEEMLRYYEGFIAYKKEGTKYEMIYE
RKEVYLDQQSIIDHVSSYIQSKGFFYEKNDLVNFFLSLKTKPFVILSGISGTGKTKIVQWFAESLGATEENGQFTLIPVR
PDWSDSSDLLGYVNLQGEFQERPLIKVLENADANPNRPYFVVLDEMNLARVEYYFSDFLSVIESRKWKDGKIVTSPVLPE
SIANKHITIPSNVYIIGTVNMDETTHPLSKRVLDRANTIEFNTVNLDYFNFLMDVEEKEAEIASNRSLETEYLHLKECFK
DNEDLVRNISTILIEINKILESVGAQVGYRIRDEICFYMAYNEQGKLLTFDESLDYQIYQKILPRLAGSDGRTEEVLKQL
YVLCANEEYDSSNSDASYAKYPRSANKLSHMLRRFEYDGFTSFWI

Sequences:

>Translated_845_residues
MLEQLIIELAKTTKQVEDIKGDKTYWIINKDDKGLDVQTKTSSGQYAKEEEPSDFNVSFELLKNAWGKIIAMRTVKSKDF
GQAGECNAFLLAFFSQLPFVNVIESGAIAFKEFQTDNLPSEKYDKVILFLEEIINGTYNPSTLSEQMDENLYSRKSRARQ
DLRLLGFLNESHEMNQLLLNEYVQSEDKNAYIAQLVLRQEYFRHALFVLGLLEKYSKDEKKEALVGFGMTIVRNSLGDNL
MVESVAKRRTGNLLDWLEQVGLINGEWIPVEQYAKDDGEKGGSMDSNLREKFLTVLNEYLQARTERFAGHKMGSFVRNEM
TTEITRLPFIDHSQYVVTGSVGQGNWAAVPWLAIMNKDITTSTQRGYYIVYLFSEDMERLYLTLAQGVTETTKEEMQKIK
EEIREQIHMSQKVKKDDEIFLGTSTKAKGYSNSTAAYIAYDVNKMPSEAELVEDLEEMLRYYEGFIAYKKEGTKYEMIYE
RKEVYLDQQSIIDHVSSYIQSKGFFYEKNDLVNFFLSLKTKPFVILSGISGTGKTKIVQWFAESLGATEENGQFTLIPVR
PDWSDSSDLLGYVNLQGEFQERPLIKVLENADANPNRPYFVVLDEMNLARVEYYFSDFLSVIESRKWKDGKIVTSPVLPE
SIANKHITIPSNVYIIGTVNMDETTHPLSKRVLDRANTIEFNTVNLDYFNFLMDVEEKEAEIASNRSLETEYLHLKECFK
DNEDLVRNISTILIEINKILESVGAQVGYRIRDEICFYMAYNEQGKLLTFDESLDYQIYQKILPRLAGSDGRTEEVLKQL
YVLCANEEYDSSNSDASYAKYPRSANKLSHMLRRFEYDGFTSFWI
>Mature_845_residues
MLEQLIIELAKTTKQVEDIKGDKTYWIINKDDKGLDVQTKTSSGQYAKEEEPSDFNVSFELLKNAWGKIIAMRTVKSKDF
GQAGECNAFLLAFFSQLPFVNVIESGAIAFKEFQTDNLPSEKYDKVILFLEEIINGTYNPSTLSEQMDENLYSRKSRARQ
DLRLLGFLNESHEMNQLLLNEYVQSEDKNAYIAQLVLRQEYFRHALFVLGLLEKYSKDEKKEALVGFGMTIVRNSLGDNL
MVESVAKRRTGNLLDWLEQVGLINGEWIPVEQYAKDDGEKGGSMDSNLREKFLTVLNEYLQARTERFAGHKMGSFVRNEM
TTEITRLPFIDHSQYVVTGSVGQGNWAAVPWLAIMNKDITTSTQRGYYIVYLFSEDMERLYLTLAQGVTETTKEEMQKIK
EEIREQIHMSQKVKKDDEIFLGTSTKAKGYSNSTAAYIAYDVNKMPSEAELVEDLEEMLRYYEGFIAYKKEGTKYEMIYE
RKEVYLDQQSIIDHVSSYIQSKGFFYEKNDLVNFFLSLKTKPFVILSGISGTGKTKIVQWFAESLGATEENGQFTLIPVR
PDWSDSSDLLGYVNLQGEFQERPLIKVLENADANPNRPYFVVLDEMNLARVEYYFSDFLSVIESRKWKDGKIVTSPVLPE
SIANKHITIPSNVYIIGTVNMDETTHPLSKRVLDRANTIEFNTVNLDYFNFLMDVEEKEAEIASNRSLETEYLHLKECFK
DNEDLVRNISTILIEINKILESVGAQVGYRIRDEICFYMAYNEQGKLLTFDESLDYQIYQKILPRLAGSDGRTEEVLKQL
YVLCANEEYDSSNSDASYAKYPRSANKLSHMLRRFEYDGFTSFWI

Specific function: Recognizes N4- And C5-Methylcytosine (And 5-Hydroxy- Methylcytosines) Produced By A Broad Range Of DNA Methylases And Appears To Act Against 5-Methylcytosine Preceded By A Purine Residue. Binds To DNA Containing Methylated Cytosines; Also Binds To GTP. [

COG id: COG1401

COG function: function code V; GTPase subunit of restriction endonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.21.- [C]

Molecular weight: Translated: 97417; Mature: 97417

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQLIIELAKTTKQVEDIKGDKTYWIINKDDKGLDVQTKTSSGQYAKEEEPSDFNVSFE
CHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCHHHH
LLKNAWGKIIAMRTVKSKDFGQAGECNAFLLAFFSQLPFVNVIESGAIAFKEFQTDNLPS
HHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCEEEHHCCCCCCCC
EKYDKVILFLEEIINGTYNPSTLSEQMDENLYSRKSRARQDLRLLGFLNESHEMNQLLLN
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EYVQSEDKNAYIAQLVLRQEYFRHALFVLGLLEKYSKDEKKEALVGFGMTIVRNSLGDNL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHH
MVESVAKRRTGNLLDWLEQVGLINGEWIPVEQYAKDDGEKGGSMDSNLREKFLTVLNEYL
HHHHHHHHHCCCHHHHHHHCCCCCCCEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
QARTERFAGHKMGSFVRNEMTTEITRLPFIDHSQYVVTGSVGQGNWAAVPWLAIMNKDIT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCC
TSTQRGYYIVYLFSEDMERLYLTLAQGVTETTKEEMQKIKEEIREQIHMSQKVKKDDEIF
CCCCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LGTSTKAKGYSNSTAAYIAYDVNKMPSEAELVEDLEEMLRYYEGFIAYKKEGTKYEMIYE
EECCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEHHHHH
RKEVYLDQQSIIDHVSSYIQSKGFFYEKNDLVNFFLSLKTKPFVILSGISGTGKTKIVQW
HHHHHCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
FAESLGATEENGQFTLIPVRPDWSDSSDLLGYVNLQGEFQERPLIKVLENADANPNRPYF
HHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCEE
VVLDEMNLARVEYYFSDFLSVIESRKWKDGKIVTSPVLPESIANKHITIPSNVYIIGTVN
EEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHCCCEEECCCCEEEEEEEC
MDETTHPLSKRVLDRANTIEFNTVNLDYFNFLMDVEEKEAEIASNRSLETEYLHLKECFK
CCCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHC
DNEDLVRNISTILIEINKILESVGAQVGYRIRDEICFYMAYNEQGKLLTFDESLDYQIYQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEEECCCCCEEEECCCCCHHHHH
KILPRLAGSDGRTEEVLKQLYVLCANEEYDSSNSDASYAKYPRSANKLSHMLRRFEYDGF
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCC
TSFWI
EECCC
>Mature Secondary Structure
MLEQLIIELAKTTKQVEDIKGDKTYWIINKDDKGLDVQTKTSSGQYAKEEEPSDFNVSFE
CHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCCCCCCCCCCCCCHHHH
LLKNAWGKIIAMRTVKSKDFGQAGECNAFLLAFFSQLPFVNVIESGAIAFKEFQTDNLPS
HHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHCCCEEEHHCCCCCCCC
EKYDKVILFLEEIINGTYNPSTLSEQMDENLYSRKSRARQDLRLLGFLNESHEMNQLLLN
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EYVQSEDKNAYIAQLVLRQEYFRHALFVLGLLEKYSKDEKKEALVGFGMTIVRNSLGDNL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHH
MVESVAKRRTGNLLDWLEQVGLINGEWIPVEQYAKDDGEKGGSMDSNLREKFLTVLNEYL
HHHHHHHHHCCCHHHHHHHCCCCCCCEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
QARTERFAGHKMGSFVRNEMTTEITRLPFIDHSQYVVTGSVGQGNWAAVPWLAIMNKDIT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCC
TSTQRGYYIVYLFSEDMERLYLTLAQGVTETTKEEMQKIKEEIREQIHMSQKVKKDDEIF
CCCCCCEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LGTSTKAKGYSNSTAAYIAYDVNKMPSEAELVEDLEEMLRYYEGFIAYKKEGTKYEMIYE
EECCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEHHHHH
RKEVYLDQQSIIDHVSSYIQSKGFFYEKNDLVNFFLSLKTKPFVILSGISGTGKTKIVQW
HHHHHCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
FAESLGATEENGQFTLIPVRPDWSDSSDLLGYVNLQGEFQERPLIKVLENADANPNRPYF
HHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHCCCCCCCCCEE
VVLDEMNLARVEYYFSDFLSVIESRKWKDGKIVTSPVLPESIANKHITIPSNVYIIGTVN
EEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHCCCEEECCCCEEEEEEEC
MDETTHPLSKRVLDRANTIEFNTVNLDYFNFLMDVEEKEAEIASNRSLETEYLHLKECFK
CCCCCCHHHHHHHHCCCCEEEEEECHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHC
DNEDLVRNISTILIEINKILESVGAQVGYRIRDEICFYMAYNEQGKLLTFDESLDYQIYQ
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCEEEEEEECCCCCEEEECCCCCHHHHH
KILPRLAGSDGRTEEVLKQLYVLCANEEYDSSNSDASYAKYPRSANKLSHMLRRFEYDGF
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCC
TSFWI
EECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Endodeoxyribonucleases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA