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The map label for this gene is trxA [H]

Identifier: 222094511

GI number: 222094511

Start: 835182

End: 835601

Strand: Reverse

Name: trxA [H]

Synonym: BCQ_0849

Alternate gene names: 222094511

Gene position: 835601-835182 (Counterclockwise)

Preceding gene: 222094512

Following gene: 222094510

Centisome position: 16.03

GC content: 30.0

Gene sequence:

>420_bases
ATGAAAAAAATGCTTATATTTGGCGGTATTATTATCGTCTTATTTGCGGCAATCTTTGCTGTAACACAAATGGAAAAGAA
AAGCGCATCAACAGATGAAAAAGGTTACTACTCAAATAAAATTTCTCTTGAGGATCTCAATAAAAATATAGAAGATAAAA
AAGAACAAACGATTTACTTTTATCAAACCTCTTGTGTTCATTGTCAAAAGGTCTCTCCTACTGTTGTACCTTTAGCAAAA
GATTTAAATGTTGATATGAAAGTAATTGATATTGAAAATTTAAACGAGCCTTGGGATAAATACAATATCCAAGGAACACC
AACAATTATTCATTTTAAAGATGGTAAAGAAGTAAGCCGTATTAGCGGCGAACAATCAAAAGAAAAGTTCAAAGAATGGT
TTGAACAAACGAAAAAATAA

Upstream 100 bases:

>100_bases
GTTCGGCTTTGTGACAATCCCGTTTTTAGCACTTATCGGCTTTATTACAATCGCTGTTTGTAGCTTTATTGTCATCAAAA
ACAAATAAGGAGATGAAAGA

Downstream 100 bases:

>100_bases
CGAGAAAAGGAAACTCCTTCTACACATGAAATGGACGTAAAATTCCAAACTAATGTATAAGGAGGGGGTTTTATGCCAGA
AGTAAAATGTTCTGTTTCCA

Product: thioredoxin

Products: NA

Alternate protein names: Disulfide oxidoreductase A; Thiol-disulfide oxidoreductase A [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MKKMLIFGGIIIVLFAAIFAVTQMEKKSASTDEKGYYSNKISLEDLNKNIEDKKEQTIYFYQTSCVHCQKVSPTVVPLAK
DLNVDMKVIDIENLNEPWDKYNIQGTPTIIHFKDGKEVSRISGEQSKEKFKEWFEQTKK

Sequences:

>Translated_139_residues
MKKMLIFGGIIIVLFAAIFAVTQMEKKSASTDEKGYYSNKISLEDLNKNIEDKKEQTIYFYQTSCVHCQKVSPTVVPLAK
DLNVDMKVIDIENLNEPWDKYNIQGTPTIIHFKDGKEVSRISGEQSKEKFKEWFEQTKK
>Mature_139_residues
MKKMLIFGGIIIVLFAAIFAVTQMEKKSASTDEKGYYSNKISLEDLNKNIEDKKEQTIYFYQTSCVHCQKVSPTVVPLAK
DLNVDMKVIDIENLNEPWDKYNIQGTPTIIHFKDGKEVSRISGEQSKEKFKEWFEQTKK

Specific function: Unknown; dispensable for production of the lantibiotic sublancin 168 and for competence for DNA uptake [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 16075; Mature: 16075

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMLIFGGIIIVLFAAIFAVTQMEKKSASTDEKGYYSNKISLEDLNKNIEDKKEQTIYF
CCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEE
YQTSCVHCQKVSPTVVPLAKDLNVDMKVIDIENLNEPWDKYNIQGTPTIIHFKDGKEVSR
EECCCEEEECCCCCEEEHHCCCCCCEEEEEECCCCCCHHHCCCCCCCEEEEECCCCHHHH
ISGEQSKEKFKEWFEQTKK
HCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKMLIFGGIIIVLFAAIFAVTQMEKKSASTDEKGYYSNKISLEDLNKNIEDKKEQTIYF
CCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEE
YQTSCVHCQKVSPTVVPLAKDLNVDMKVIDIENLNEPWDKYNIQGTPTIIHFKDGKEVSR
EECCCEEEECCCCCEEEHHCCCCCCEEEEEECCCCCCHHHCCCCCCCEEEEECCCCHHHH
ISGEQSKEKFKEWFEQTKK
HCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 10455116; 11872755 [H]