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The map label for this gene is rocE [H]

Identifier: 222094459

GI number: 222094459

Start: 775554

End: 776969

Strand: Reverse

Name: rocE [H]

Synonym: BCQ_0773

Alternate gene names: 222094459

Gene position: 776969-775554 (Counterclockwise)

Preceding gene: 222094468

Following gene: 222094458

Centisome position: 14.9

GC content: 37.85

Gene sequence:

>1416_bases
ATGAATCAACAAGTAGAACAAACAGATTTAAAACGTACAATGAAAAGTAGACACCTATTTATGATCGCACTTGGTGGTGT
TATCGGAACTGGCCTATTTATGGGATCTGGTCAAATCGTCCATAACGCCGGCCCTGGTGGTGCTATTCTTGCATTTTTAG
TCGGTGGATTTGTTATGTATTTAACGATGTTATGTCTTGGTGAATTATCCGTAGCTATGCCAGAAGCAGGTTCATTCCAA
AGCTATGCAAGCAAATTTATTTCACCTGGTTTTGGTTTTGTTGTCGGTTGGATGTATTGGTTAAATTGGGCTGTTACAGT
TGGAGTAGAGTTAACAACTGTAAGTATTTTAATGAAACGATGGTTTCCAGACGTTTCTTCGTGGATTTGGTGTGTTACAT
TTGCGGCAGCACTCTTTCTTGTAAACGCTTTATCAGCAAAAGCATATGCAGAAGCAGAATTTTGGTTCGCAAGTGTAAAA
GTCGCAACTATTGTTGTTTTCATCGTACTCGGTGGTGCAGTTATGTTCGGTCTACTAGACTTTAACGGAAAACCAGCTCC
AATGCTTCACAATTTCACTGAAAATGGCGGCCTATTTCCAAATGGTGCATTAGCTGTTCTTCTTACGATGATTACAGTAA
ATTACTCCTTCCAAGGAACAGAATTAATCGGAATTGCTTCAGGAGAAAGTGAAAATCCTGAAAAAACAATTCCTAAAGCA
ATCAAAAATACCATTTGGCGCACACTATTCTTCTTCGTCCTAGCAATATCAGTTGTTGTAGGTTTACTCCCGTGGCAAGA
GGCTAATCTAGTCGAAAGTCCATTTGTACTTGTATTTGATGTAGCTGGTGTTCCATATGCAGCAGACATTATGAACTTTG
TTATTATTACAGCTGTATTATCCGTAGCCAATTCTGGTCTATACGCAAATTCGCGTATGCTTTGGGCGATGGCAAAACAA
GGAATGGCAAGTCCAGCATTTACGAAATTAACTAAAAAAGGTGTACCACTAAACGCATTGATTTTCAGTCTAATCTTTGC
AAGTCTATCCCTATTAACAAGTATATTTGCAGCAGATACTGTCTTTTTAGTTTTAACATCTATCGCAGCAATGGCTGCTG
TTGTCGTTTGGATGTCAATTGCGGCTTCACAGTTTTTCTTCCGTAGAAACTTCGTGAAAAACGGTGGTGACATAAATGAT
TTAAAATATCGCACACCACTTTATCCGCTCGTTCCAATCGTAGCGTTCTCACTCAATTTCATTACATTTGTTAGTTTAGC
TTTCATTCCAGATCAGAGAATCGCTCTTTATTGCGGCATTCCATTTATGGTCATTTGTTACATTTTATATCAAGTGAAAT
ATAAAAAAATTGTCACATTTGAACAACAACAGACTATTTCACAAGAAATAAACTAA

Upstream 100 bases:

>100_bases
AGCAAATAAACTGAGTATGTGTCACATCCCCCACTAATGATTAAAAACTCAGAATGAAAACCAGTTAACACATATAAGAA
AATAACGGGGTGAGGGGCAT

Downstream 100 bases:

>100_bases
ATATACGAAATATTCAGCTATCTTTCTTATGATAAGATAGCTTTTTTCTATTTCTTGGGTATCCTGGTATAACTTTATTT
ATCTTAAAATTTTCACAATC

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MNQQVEQTDLKRTMKSRHLFMIALGGVIGTGLFMGSGQIVHNAGPGGAILAFLVGGFVMYLTMLCLGELSVAMPEAGSFQ
SYASKFISPGFGFVVGWMYWLNWAVTVGVELTTVSILMKRWFPDVSSWIWCVTFAAALFLVNALSAKAYAEAEFWFASVK
VATIVVFIVLGGAVMFGLLDFNGKPAPMLHNFTENGGLFPNGALAVLLTMITVNYSFQGTELIGIASGESENPEKTIPKA
IKNTIWRTLFFFVLAISVVVGLLPWQEANLVESPFVLVFDVAGVPYAADIMNFVIITAVLSVANSGLYANSRMLWAMAKQ
GMASPAFTKLTKKGVPLNALIFSLIFASLSLLTSIFAADTVFLVLTSIAAMAAVVVWMSIAASQFFFRRNFVKNGGDIND
LKYRTPLYPLVPIVAFSLNFITFVSLAFIPDQRIALYCGIPFMVICYILYQVKYKKIVTFEQQQTISQEIN

Sequences:

>Translated_471_residues
MNQQVEQTDLKRTMKSRHLFMIALGGVIGTGLFMGSGQIVHNAGPGGAILAFLVGGFVMYLTMLCLGELSVAMPEAGSFQ
SYASKFISPGFGFVVGWMYWLNWAVTVGVELTTVSILMKRWFPDVSSWIWCVTFAAALFLVNALSAKAYAEAEFWFASVK
VATIVVFIVLGGAVMFGLLDFNGKPAPMLHNFTENGGLFPNGALAVLLTMITVNYSFQGTELIGIASGESENPEKTIPKA
IKNTIWRTLFFFVLAISVVVGLLPWQEANLVESPFVLVFDVAGVPYAADIMNFVIITAVLSVANSGLYANSRMLWAMAKQ
GMASPAFTKLTKKGVPLNALIFSLIFASLSLLTSIFAADTVFLVLTSIAAMAAVVVWMSIAASQFFFRRNFVKNGGDIND
LKYRTPLYPLVPIVAFSLNFITFVSLAFIPDQRIALYCGIPFMVICYILYQVKYKKIVTFEQQQTISQEIN
>Mature_471_residues
MNQQVEQTDLKRTMKSRHLFMIALGGVIGTGLFMGSGQIVHNAGPGGAILAFLVGGFVMYLTMLCLGELSVAMPEAGSFQ
SYASKFISPGFGFVVGWMYWLNWAVTVGVELTTVSILMKRWFPDVSSWIWCVTFAAALFLVNALSAKAYAEAEFWFASVK
VATIVVFIVLGGAVMFGLLDFNGKPAPMLHNFTENGGLFPNGALAVLLTMITVNYSFQGTELIGIASGESENPEKTIPKA
IKNTIWRTLFFFVLAISVVVGLLPWQEANLVESPFVLVFDVAGVPYAADIMNFVIITAVLSVANSGLYANSRMLWAMAKQ
GMASPAFTKLTKKGVPLNALIFSLIFASLSLLTSIFAADTVFLVLTSIAAMAAVVVWMSIAASQFFFRRNFVKNGGDIND
LKYRTPLYPLVPIVAFSLNFITFVSLAFIPDQRIALYCGIPFMVICYILYQVKYKKIVTFEQQQTISQEIN

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI33286428, Length=357, Percent_Identity=24.9299719887955, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI110347453, Length=344, Percent_Identity=23.2558139534884, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI181337167, Length=337, Percent_Identity=26.1127596439169, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081708, Length=465, Percent_Identity=49.6774193548387, Blast_Score=487, Evalue=1e-139,
Organism=Escherichia coli, GI1788480, Length=480, Percent_Identity=42.5, Blast_Score=389, Evalue=1e-109,
Organism=Escherichia coli, GI1786302, Length=455, Percent_Identity=35.6043956043956, Blast_Score=297, Evalue=9e-82,
Organism=Escherichia coli, GI48994972, Length=451, Percent_Identity=37.4722838137472, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1786602, Length=461, Percent_Identity=36.0086767895879, Blast_Score=275, Evalue=3e-75,
Organism=Escherichia coli, GI1786789, Length=430, Percent_Identity=34.8837209302326, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1789017, Length=467, Percent_Identity=33.1905781584582, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI87081915, Length=406, Percent_Identity=35.2216748768473, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1790653, Length=440, Percent_Identity=34.0909090909091, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI87081869, Length=240, Percent_Identity=30.4166666666667, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082250, Length=337, Percent_Identity=27.0029673590504, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082023, Length=334, Percent_Identity=25.748502994012, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI2367353, Length=336, Percent_Identity=24.1071428571429, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=383, Percent_Identity=23.7597911227154, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=373, Percent_Identity=23.3243967828418, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320772, Length=478, Percent_Identity=31.7991631799163, Blast_Score=244, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6324061, Length=475, Percent_Identity=32, Blast_Score=242, Evalue=8e-65,
Organism=Saccharomyces cerevisiae, GI6324553, Length=414, Percent_Identity=33.3333333333333, Blast_Score=233, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6320717, Length=419, Percent_Identity=31.0262529832936, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6322892, Length=413, Percent_Identity=31.9612590799031, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6319543, Length=412, Percent_Identity=30.0970873786408, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6324059, Length=474, Percent_Identity=31.0126582278481, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6321629, Length=490, Percent_Identity=26.9387755102041, Blast_Score=206, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6324990, Length=487, Percent_Identity=28.7474332648871, Blast_Score=206, Evalue=8e-54,
Organism=Saccharomyces cerevisiae, GI6319824, Length=419, Percent_Identity=30.5489260143198, Blast_Score=205, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6319542, Length=413, Percent_Identity=30.9927360774818, Blast_Score=203, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6324924, Length=485, Percent_Identity=28.4536082474227, Blast_Score=196, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6320251, Length=413, Percent_Identity=30.2663438256659, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6321053, Length=420, Percent_Identity=27.1428571428571, Blast_Score=184, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6322967, Length=471, Percent_Identity=29.2993630573248, Blast_Score=177, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6324981, Length=484, Percent_Identity=28.7190082644628, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319608, Length=433, Percent_Identity=26.7898383371824, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6320364, Length=536, Percent_Identity=24.4402985074627, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24667468, Length=378, Percent_Identity=26.4550264550265, Blast_Score=89, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51554; Mature: 51554

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQQVEQTDLKRTMKSRHLFMIALGGVIGTGLFMGSGQIVHNAGPGGAILAFLVGGFVMY
CCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHEECCCCEEECCCCCHHHHHHHHHHHHHH
LTMLCLGELSVAMPEAGSFQSYASKFISPGFGFVVGWMYWLNWAVTVGVELTTVSILMKR
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
WFPDVSSWIWCVTFAAALFLVNALSAKAYAEAEFWFASVKVATIVVFIVLGGAVMFGLLD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FNGKPAPMLHNFTENGGLFPNGALAVLLTMITVNYSFQGTELIGIASGESENPEKTIPKA
CCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IKNTIWRTLFFFVLAISVVVGLLPWQEANLVESPFVLVFDVAGVPYAADIMNFVIITAVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYANSRMLWAMAKQGMASPAFTKLTKKGVPLNALIFSLIFASLSLLTSIFAADT
HHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VFLVLTSIAAMAAVVVWMSIAASQFFFRRNFVKNGGDINDLKYRTPLYPLVPIVAFSLNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ITFVSLAFIPDQRIALYCGIPFMVICYILYQVKYKKIVTFEQQQTISQEIN
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQQVEQTDLKRTMKSRHLFMIALGGVIGTGLFMGSGQIVHNAGPGGAILAFLVGGFVMY
CCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHEECCCCEEECCCCCHHHHHHHHHHHHHH
LTMLCLGELSVAMPEAGSFQSYASKFISPGFGFVVGWMYWLNWAVTVGVELTTVSILMKR
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
WFPDVSSWIWCVTFAAALFLVNALSAKAYAEAEFWFASVKVATIVVFIVLGGAVMFGLLD
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FNGKPAPMLHNFTENGGLFPNGALAVLLTMITVNYSFQGTELIGIASGESENPEKTIPKA
CCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IKNTIWRTLFFFVLAISVVVGLLPWQEANLVESPFVLVFDVAGVPYAADIMNFVIITAVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYANSRMLWAMAKQGMASPAFTKLTKKGVPLNALIFSLIFASLSLLTSIFAADT
HHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VFLVLTSIAAMAAVVVWMSIAASQFFFRRNFVKNGGDINDLKYRTPLYPLVPIVAFSLNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ITFVSLAFIPDQRIALYCGIPFMVICYILYQVKYKKIVTFEQQQTISQEIN
HHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]