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The map label for this gene is napA [H]

Identifier: 222094454

GI number: 222094454

Start: 769451

End: 771280

Strand: Reverse

Name: napA [H]

Synonym: BCQ_0768

Alternate gene names: 222094454

Gene position: 771280-769451 (Counterclockwise)

Preceding gene: 222094455

Following gene: 222094453

Centisome position: 14.79

GC content: 35.9

Gene sequence:

>1830_bases
ATGGAACATCACACTTCTGTTCTATCACTTATGGTTGTCGTTGCAATCGCGTTTTTCGTTCCCCTTTTGTTACAACGCTT
TAAATTAAAAGCACTTCCTGTCGTCGTTGCAGAAATCATCGCAGGAATCTTTGTAGGTAAAAGTGGGTTTAATATTATTG
AGCCAGATATGTGGCTTCAAGTCTTATCGACACTAGGATTTATCTTTCTTATGTTTTTAAGCGGTTTAGAAATTGATTTT
TCTATCTTTAAACAAAAAGGGAAAAAGAATACGACAAACGAACCAAACACATTTCAAGCAGCAAGTATTATCTTCTTATT
TATTTTCATCCTATCTTATGCCCTATCACTACTATTCGTATGGCTAGGATTTGTAGATAATGCAATGTTTATGACTTTAA
TCATTTCAACAATCTCTTTAGGTGTTGTCGTACCAACACTAAAAGAGAATAACTTAGGAAAAACAGCAATTGGGCAAATC
ATTTTATTAGTCGCTGTTATTGCGGATTTAGTTACAATGATTTTACTCGCTGTATTCGTCGGATTAAATTCCGAAAGCGG
CCAAAGCATGTGGCTTCTTCTTCTTCTATTCGGCGCTGGTATTGTTATTTACTTCGTTGCAAAACGTTTTAAAAACATTC
CATACTTGGATAACTTAAAAGCTGGGAGTGTACAAATTGATACACGAGCTGTTTTTGCACTCATCTTAATATTAGTTGGG
TTATCTGAATCCGTTGGAGCTGAAAATATTTTAGGCGCCTTCTTAGCGGGTGTACTCGTATCATTATTATCACCAAATGA
AGATATGGTTGAAAAACTGGATTCTATCGGATACGGTTTCTTCATTCCTATTTTCTTCGTAATGGTTGGTGTAAATTTAG
AGGTTTGGTCTATTTTTAAAGAGCCTTCTAGTATGCTAATGATTCCAATTCTAATTGTAGGACTCTTTATCTCAAAACTG
TTACCATCACTCGTTTTACGAAAATGGTATCCACGTAATATCGTACTGGGGAGTGCCATCTTATTAACATCGACACTTTC
TTTAGTTATTGCAGCTGCACAAATTGGTGAAAAGCTAGGGATCATCAGTCCAAGTTTATCTGCTTCCCTTATTTTAAGCG
CAGTTATTACTTGTATTTTTGCGCCTATATTATTTAAAAAGATGTTCCCAAAAGTAGAAACGCCAAAACCAAAAGTTTCT
ATTATTGGTGCGAGCAGAATTACCCTTCCGTTATCACTTGATTTAAAACGAGAAGATTATGACGTAACACTATATATGAT
GCGTCAAAACAAAATAAACGATGAGGAAGCAAAATCACATGACTTCCCTATCGTGAAATTAGATGACATCACAATCGCAT
CGTTAACTGAACAAACAGCCTTTCATGCAGACCGAGTTGTTGTTGCAACAAGTGATGATGAGCAAAACTTACTATTAGCA
GAACACGCAAAAGAACTAGGTGTTGAACATGTTATTGCAAGTGTAGAAGATCCACTTCTACAAGAAAAAGCAACACAAGA
ACATATCGCCGTATTCTCAACAATTAACTCTACACGTATTCTATTACGTGCGCTAATTGATAAACCGAGTCTCGTTCGCT
TAATTACAACAGCAAACGAAACAGTCCGTGAAGTTGAACTACGGAGCAATAAATATAACGGCGTTGCACTTCGTCGCCTT
CCGTTTTTAGGTGATGTACTAGTCATTCAAATTTATCGTGGAAATAAAGCATTAATCCCACATGGTGATACAAGACTACA
ACACGGTGATACATTACTTGTAACAGGCTCAAAAGAACATATCGATACACTAAAAAACATATTAGAATAA

Upstream 100 bases:

>100_bases
AAGAAAACTCTTTCTTTATGAAATCGAATCCATATGCGTTGCTTTTCTACCTATTATATGGCTAAATAAGTACTATATTT
ATTTGAAGGGAGAGAACGCA

Downstream 100 bases:

>100_bases
AAAAAATGCCCCTCACATAATTGAGGGGCATTTTTTTCCATTTCATATGGTAAAATGTTACTATCACATATTATGAGGAT
GGATTACATTATGTCTATTA

Product: Na+/H+ antiporter

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MEHHTSVLSLMVVVAIAFFVPLLLQRFKLKALPVVVAEIIAGIFVGKSGFNIIEPDMWLQVLSTLGFIFLMFLSGLEIDF
SIFKQKGKKNTTNEPNTFQAASIIFLFIFILSYALSLLFVWLGFVDNAMFMTLIISTISLGVVVPTLKENNLGKTAIGQI
ILLVAVIADLVTMILLAVFVGLNSESGQSMWLLLLLFGAGIVIYFVAKRFKNIPYLDNLKAGSVQIDTRAVFALILILVG
LSESVGAENILGAFLAGVLVSLLSPNEDMVEKLDSIGYGFFIPIFFVMVGVNLEVWSIFKEPSSMLMIPILIVGLFISKL
LPSLVLRKWYPRNIVLGSAILLTSTLSLVIAAAQIGEKLGIISPSLSASLILSAVITCIFAPILFKKMFPKVETPKPKVS
IIGASRITLPLSLDLKREDYDVTLYMMRQNKINDEEAKSHDFPIVKLDDITIASLTEQTAFHADRVVVATSDDEQNLLLA
EHAKELGVEHVIASVEDPLLQEKATQEHIAVFSTINSTRILLRALIDKPSLVRLITTANETVREVELRSNKYNGVALRRL
PFLGDVLVIQIYRGNKALIPHGDTRLQHGDTLLVTGSKEHIDTLKNILE

Sequences:

>Translated_609_residues
MEHHTSVLSLMVVVAIAFFVPLLLQRFKLKALPVVVAEIIAGIFVGKSGFNIIEPDMWLQVLSTLGFIFLMFLSGLEIDF
SIFKQKGKKNTTNEPNTFQAASIIFLFIFILSYALSLLFVWLGFVDNAMFMTLIISTISLGVVVPTLKENNLGKTAIGQI
ILLVAVIADLVTMILLAVFVGLNSESGQSMWLLLLLFGAGIVIYFVAKRFKNIPYLDNLKAGSVQIDTRAVFALILILVG
LSESVGAENILGAFLAGVLVSLLSPNEDMVEKLDSIGYGFFIPIFFVMVGVNLEVWSIFKEPSSMLMIPILIVGLFISKL
LPSLVLRKWYPRNIVLGSAILLTSTLSLVIAAAQIGEKLGIISPSLSASLILSAVITCIFAPILFKKMFPKVETPKPKVS
IIGASRITLPLSLDLKREDYDVTLYMMRQNKINDEEAKSHDFPIVKLDDITIASLTEQTAFHADRVVVATSDDEQNLLLA
EHAKELGVEHVIASVEDPLLQEKATQEHIAVFSTINSTRILLRALIDKPSLVRLITTANETVREVELRSNKYNGVALRRL
PFLGDVLVIQIYRGNKALIPHGDTRLQHGDTLLVTGSKEHIDTLKNILE
>Mature_609_residues
MEHHTSVLSLMVVVAIAFFVPLLLQRFKLKALPVVVAEIIAGIFVGKSGFNIIEPDMWLQVLSTLGFIFLMFLSGLEIDF
SIFKQKGKKNTTNEPNTFQAASIIFLFIFILSYALSLLFVWLGFVDNAMFMTLIISTISLGVVVPTLKENNLGKTAIGQI
ILLVAVIADLVTMILLAVFVGLNSESGQSMWLLLLLFGAGIVIYFVAKRFKNIPYLDNLKAGSVQIDTRAVFALILILVG
LSESVGAENILGAFLAGVLVSLLSPNEDMVEKLDSIGYGFFIPIFFVMVGVNLEVWSIFKEPSSMLMIPILIVGLFISKL
LPSLVLRKWYPRNIVLGSAILLTSTLSLVIAAAQIGEKLGIISPSLSASLILSAVITCIFAPILFKKMFPKVETPKPKVS
IIGASRITLPLSLDLKREDYDVTLYMMRQNKINDEEAKSHDFPIVKLDDITIASLTEQTAFHADRVVVATSDDEQNLLLA
EHAKELGVEHVIASVEDPLLQEKATQEHIAVFSTINSTRILLRALIDKPSLVRLITTANETVREVELRSNKYNGVALRRL
PFLGDVLVIQIYRGNKALIPHGDTRLQHGDTLLVTGSKEHIDTLKNILE

Specific function: Probable Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786232, Length=519, Percent_Identity=22.1579961464355, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322367, Length=402, Percent_Identity=23.6318407960199, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 67112; Mature: 67112

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHHTSVLSLMVVVAIAFFVPLLLQRFKLKALPVVVAEIIAGIFVGKSGFNIIEPDMWLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
VLSTLGFIFLMFLSGLEIDFSIFKQKGKKNTTNEPNTFQAASIIFLFIFILSYALSLLFV
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WLGFVDNAMFMTLIISTISLGVVVPTLKENNLGKTAIGQIILLVAVIADLVTMILLAVFV
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLNSESGQSMWLLLLLFGAGIVIYFVAKRFKNIPYLDNLKAGSVQIDTRAVFALILILVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHC
LSESVGAENILGAFLAGVLVSLLSPNEDMVEKLDSIGYGFFIPIFFVMVGVNLEVWSIFK
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
EPSSMLMIPILIVGLFISKLLPSLVLRKWYPRNIVLGSAILLTSTLSLVIAAAQIGEKLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IISPSLSASLILSAVITCIFAPILFKKMFPKVETPKPKVSIIGASRITLPLSLDLKREDY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEEECCCCCC
DVTLYMMRQNKINDEEAKSHDFPIVKLDDITIASLTEQTAFHADRVVVATSDDEQNLLLA
CEEEEEEECCCCCCHHHHCCCCCEEEECCEEHHHHHHHHHHCCCEEEEEECCCCCCHHHH
EHAKELGVEHVIASVEDPLLQEKATQEHIAVFSTINSTRILLRALIDKPSLVRLITTANE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHH
TVREVELRSNKYNGVALRRLPFLGDVLVIQIYRGNKALIPHGDTRLQHGDTLLVTGSKEH
HHHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCCEEECCCCCCCCCCCCEEEEECCHHH
IDTLKNILE
HHHHHHHHC
>Mature Secondary Structure
MEHHTSVLSLMVVVAIAFFVPLLLQRFKLKALPVVVAEIIAGIFVGKSGFNIIEPDMWLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
VLSTLGFIFLMFLSGLEIDFSIFKQKGKKNTTNEPNTFQAASIIFLFIFILSYALSLLFV
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WLGFVDNAMFMTLIISTISLGVVVPTLKENNLGKTAIGQIILLVAVIADLVTMILLAVFV
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLNSESGQSMWLLLLLFGAGIVIYFVAKRFKNIPYLDNLKAGSVQIDTRAVFALILILVG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHHHC
LSESVGAENILGAFLAGVLVSLLSPNEDMVEKLDSIGYGFFIPIFFVMVGVNLEVWSIFK
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHH
EPSSMLMIPILIVGLFISKLLPSLVLRKWYPRNIVLGSAILLTSTLSLVIAAAQIGEKLG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IISPSLSASLILSAVITCIFAPILFKKMFPKVETPKPKVSIIGASRITLPLSLDLKREDY
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEEECCCCCC
DVTLYMMRQNKINDEEAKSHDFPIVKLDDITIASLTEQTAFHADRVVVATSDDEQNLLLA
CEEEEEEECCCCCCHHHHCCCCCEEEECCEEHHHHHHHHHHCCCEEEEEECCCCCCHHHH
EHAKELGVEHVIASVEDPLLQEKATQEHIAVFSTINSTRILLRALIDKPSLVRLITTANE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHH
TVREVELRSNKYNGVALRRLPFLGDVLVIQIYRGNKALIPHGDTRLQHGDTLLVTGSKEH
HHHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCCEEECCCCCCCCCCCCEEEEECCHHH
IDTLKNILE
HHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]