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The map label for this gene is glpT [H]

Identifier: 222094415

GI number: 222094415

Start: 727672

End: 729021

Strand: Reverse

Name: glpT [H]

Synonym: BCQ_0729

Alternate gene names: 222094415

Gene position: 729021-727672 (Counterclockwise)

Preceding gene: 222094426

Following gene: 222094414

Centisome position: 13.98

GC content: 39.26

Gene sequence:

>1350_bases
ATGTTTTTCACACAATTCTTTAAACCTGCGCCCCACGCGGAACGCTTACCAGCTGATCGCGTTGATAGTGAATACCGTAA
ATTACGTTTACAAGTATTCTTAGGTATTTTCATCGGCTATGCAGGCTACTACTTTGTTCGAAAAAACTTTTCACTAGCAA
TGCCATACTTAATTGAACAAGGCTTTAGTAAAGGGGAGCTTGGGGTTATCCTTTCAGCAGTTTCTATCGCTTACGGATTA
AGTAAATTTCTTATGGGTATCGTATCCGATCGTTGTAATCCTCGCTACTTTTTAGCAGCTGGGCTATTTTTATCAGGTAT
CATTAATATTATTTTCGGCTCATTTTCTTTCATTACAACGAGCATTATACTTATGTTTGTACTTCAGTTTTTAAATGGAT
GGGTACAAGGGATGGGATGGCCTCCTTGTGGTCGTACAATGGTTCACTGGTTCTCTATTAGTGAACGTGGTACAAAAATG
TCTATTTGGAACGTCGCTCATAATGTCGGTGGCGCACTTATGCCTTCCCTTGTAACATTAGGGTTATATTTCTTTGCAAA
TGACTGGAAAAGTATTTTTTACTTCCCAGGTATTCTTTCAATTTTAGTTGGTATTTATGTATTAATTACGATGAGAGATA
CACCTCAATCTTGCGGATTACCTTCTATTGAAGAACATACTGGAGAATATCCACCAGATGAAAAAGTACAAGATCGCGAA
CGCGAACTTTCAGTAAAGGAAATTTTATTTACATACGTACTAAACAATAAATTTTTATGGTACATCGCTATTGCGAACGT
TTTCGTATATTTCGTACGTTACGGTGTTGTAGACTGGGCTCCTACTTATTTAGTAGAAGAAAAAAGCTTTACTCATAGTA
GCTCACGTACAGCTTATGCTCTATATGAATGGGCTGGTATTCCAGGTACACTTCTTTGCGGCTGGATGAGTGATAAACTA
TTTAAAGGACGCCGCGCACCTGCTGGTATTTTATTTATGGTTGGTGTATTTATCGCCGTTCTTGTATACTGGCTAAACCC
TCCTGGTAATCCAATGGTTGATAGTATCGCACTTGTTGCAATTGGATTTTTAATTTACGGACCTGTTATGTTAATTGGTC
TACACGCTCTTGACTTAGCACCAAAGAAAGCGGCTGGAACTGCAGCTGGATTAACTGGCTTCTTCGGTTACTTAGGCGGA
GCAGCTTTCGCTAGTGCCGCTATGGGCTTTATCGTCGATGCATTCGGATGGGATGGCGGATTCATCTTATTACTTGTATC
TTGTGTACTTGCAATGTTCTTCCTTGCTCTTACTTTAAAGACAGGATCTCCAAAACAAAAGCAAGCTTAA

Upstream 100 bases:

>100_bases
TATGAATCATAAAAAAGGAAACTTTTTTATATTTCATGGCCTTTTTATATTCTCTCTGACTTACGACACTTCGAATTAAT
TTGGGGAGGATTTTCATTTT

Downstream 100 bases:

>100_bases
GCACTAATATTATTCTTATCAAAAAAAGAGAGACTGTTCTTTCCAGAACGTCTCTCTTTTTTCTACATATAATACTTTTT
TCTTACAAAAGATTTATTTC

Product: glycerol-3-phosphate transporter

Products: Proton [Cytoplasm]; glycerol-3-phosphate [Cytoplasm] [C]

Alternate protein names: G-3-P transporter; G-3-P permease [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MFFTQFFKPAPHAERLPADRVDSEYRKLRLQVFLGIFIGYAGYYFVRKNFSLAMPYLIEQGFSKGELGVILSAVSIAYGL
SKFLMGIVSDRCNPRYFLAAGLFLSGIINIIFGSFSFITTSIILMFVLQFLNGWVQGMGWPPCGRTMVHWFSISERGTKM
SIWNVAHNVGGALMPSLVTLGLYFFANDWKSIFYFPGILSILVGIYVLITMRDTPQSCGLPSIEEHTGEYPPDEKVQDRE
RELSVKEILFTYVLNNKFLWYIAIANVFVYFVRYGVVDWAPTYLVEEKSFTHSSSRTAYALYEWAGIPGTLLCGWMSDKL
FKGRRAPAGILFMVGVFIAVLVYWLNPPGNPMVDSIALVAIGFLIYGPVMLIGLHALDLAPKKAAGTAAGLTGFFGYLGG
AAFASAAMGFIVDAFGWDGGFILLLVSCVLAMFFLALTLKTGSPKQKQA

Sequences:

>Translated_449_residues
MFFTQFFKPAPHAERLPADRVDSEYRKLRLQVFLGIFIGYAGYYFVRKNFSLAMPYLIEQGFSKGELGVILSAVSIAYGL
SKFLMGIVSDRCNPRYFLAAGLFLSGIINIIFGSFSFITTSIILMFVLQFLNGWVQGMGWPPCGRTMVHWFSISERGTKM
SIWNVAHNVGGALMPSLVTLGLYFFANDWKSIFYFPGILSILVGIYVLITMRDTPQSCGLPSIEEHTGEYPPDEKVQDRE
RELSVKEILFTYVLNNKFLWYIAIANVFVYFVRYGVVDWAPTYLVEEKSFTHSSSRTAYALYEWAGIPGTLLCGWMSDKL
FKGRRAPAGILFMVGVFIAVLVYWLNPPGNPMVDSIALVAIGFLIYGPVMLIGLHALDLAPKKAAGTAAGLTGFFGYLGG
AAFASAAMGFIVDAFGWDGGFILLLVSCVLAMFFLALTLKTGSPKQKQA
>Mature_449_residues
MFFTQFFKPAPHAERLPADRVDSEYRKLRLQVFLGIFIGYAGYYFVRKNFSLAMPYLIEQGFSKGELGVILSAVSIAYGL
SKFLMGIVSDRCNPRYFLAAGLFLSGIINIIFGSFSFITTSIILMFVLQFLNGWVQGMGWPPCGRTMVHWFSISERGTKM
SIWNVAHNVGGALMPSLVTLGLYFFANDWKSIFYFPGILSILVGIYVLITMRDTPQSCGLPSIEEHTGEYPPDEKVQDRE
RELSVKEILFTYVLNNKFLWYIAIANVFVYFVRYGVVDWAPTYLVEEKSFTHSSSRTAYALYEWAGIPGTLLCGWMSDKL
FKGRRAPAGILFMVGVFIAVLVYWLNPPGNPMVDSIALVAIGFLIYGPVMLIGLHALDLAPKKAAGTAAGLTGFFGYLGG
AAFASAAMGFIVDAFGWDGGFILLLVSCVLAMFFLALTLKTGSPKQKQA

Specific function: Responsible for glycerol-3-phosphate uptake [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=430, Percent_Identity=29.0697674418605, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI4503847, Length=430, Percent_Identity=29.0697674418605, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI256219483, Length=430, Percent_Identity=29.0697674418605, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI256219543, Length=452, Percent_Identity=27.6548672566372, Blast_Score=175, Evalue=6e-44,
Organism=Homo sapiens, GI256219564, Length=361, Percent_Identity=26.5927977839335, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI223717983, Length=470, Percent_Identity=25.7446808510638, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI38093649, Length=470, Percent_Identity=25.7446808510638, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI46361976, Length=463, Percent_Identity=24.1900647948164, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI49619231, Length=416, Percent_Identity=22.8365384615385, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI14150047, Length=330, Percent_Identity=23.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788573, Length=442, Percent_Identity=60.8597285067873, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI87082310, Length=446, Percent_Identity=37.4439461883408, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI2367259, Length=459, Percent_Identity=32.8976034858388, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI2367379, Length=435, Percent_Identity=25.0574712643678, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789515, Length=396, Percent_Identity=25, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082320, Length=439, Percent_Identity=23.9179954441913, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789152, Length=427, Percent_Identity=23.8875878220141, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17564202, Length=428, Percent_Identity=25.9345794392523, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI133901856, Length=439, Percent_Identity=25.0569476082005, Blast_Score=95, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI133901854, Length=438, Percent_Identity=25.1141552511416, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17564204, Length=365, Percent_Identity=26.8493150684932, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17542316, Length=456, Percent_Identity=24.5614035087719, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI133930953, Length=479, Percent_Identity=23.1732776617954, Blast_Score=85, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17561094, Length=415, Percent_Identity=21.9277108433735, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17539138, Length=329, Percent_Identity=24.0121580547112, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24656866, Length=470, Percent_Identity=23.4042553191489, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45550478, Length=470, Percent_Identity=23.4042553191489, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24656861, Length=470, Percent_Identity=23.4042553191489, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005267
- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49828; Mature: 49828

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50850 MFS ; PS00942 GLPT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFTQFFKPAPHAERLPADRVDSEYRKLRLQVFLGIFIGYAGYYFVRKNFSLAMPYLIEQ
CCCHHHCCCCCCHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
GFSKGELGVILSAVSIAYGLSKFLMGIVSDRCNPRYFLAAGLFLSGIINIIFGSFSFITT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SIILMFVLQFLNGWVQGMGWPPCGRTMVHWFSISERGTKMSIWNVAHNVGGALMPSLVTL
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHEEEECCCCCEEHHHHHHHHCCHHHHHHHHHH
GLYFFANDWKSIFYFPGILSILVGIYVLITMRDTPQSCGLPSIEEHTGEYPPDEKVQDRE
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHCCCCCCCCCHHHHH
RELSVKEILFTYVLNNKFLWYIAIANVFVYFVRYGVVDWAPTYLVEEKSFTHSSSRTAYA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCEEE
LYEWAGIPGTLLCGWMSDKLFKGRRAPAGILFMVGVFIAVLVYWLNPPGNPMVDSIALVA
EEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IGFLIYGPVMLIGLHALDLAPKKAAGTAAGLTGFFGYLGGAAFASAAMGFIVDAFGWDGG
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
FILLLVSCVLAMFFLALTLKTGSPKQKQA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; glycerol-3-phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + glycerol-3-phosphate [Periplasm] = Proton [Cytoplasm] + glycerol-3-phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8012593; 9384377 [H]