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The map label for this gene is colA [H]

Identifier: 222094306

GI number: 222094306

Start: 605439

End: 608336

Strand: Direct

Name: colA [H]

Synonym: BCQ_0620

Alternate gene names: 222094306

Gene position: 605439-608336 (Clockwise)

Preceding gene: 222094304

Following gene: 222094307

Centisome position: 11.61

GC content: 34.75

Gene sequence:

>2898_bases
ATGAACAAGAAATCAAAGATTAATAAAGTTATGCTTAGCATTAGTACAATGGCTCTATCATTAGGGGCGCTTCAAGCTCC
TGCATCAGCAGAAGAAAAAGTACCGTATAACGTGTTGAAAACGAAACCAGTTGGAATTGAAAAACCAGTAGATGAGATTG
GGCACGTTTCTAAAGCGGAGGAAACATTATCGTTTCAAGAACGTTTAAAAGTAGGAGACTTTTCACAGCGACCAGCATCT
ATTCCGAACAAAGCGGCAGTAAAGCAAGTTAAGGAAAGTTATTCAATGGCTGATTTAAACAAAATGAATGATCAAGAATT
AGTTGAAACGTTAGGCTGTATTAAGTGGCACCAAATTACAGATTTATTCCAGTTTAATGAAGATGCAAAAGCTTTTTATA
AAGATAAGGGGAAAATGCAAGTCATTATAGATGAATTAGCTCATCGAGGTAGTACGTTTACGAGAGATGATTCAAAAGGA
ATTCAAACATTTACGGAAGTGTTACGTTCAGCTTTTTATCTGGCATTTTATAATAACGAATTAAGTGAATTAAATGAAAG
AAGCTTTCAGGACAAATGTTTACCTGCTTTAAAAGCAATCGCAAAAAATCCAAACTTTAAGCTTGGTACAGCTGAACAAG
ATACAGTCGTATCTGCATACGGTAAATTAATTAGTAATGCGTCAAGTGATGTTGAAACAGTTCAATACGCATCGAATATT
TTAAAGCAATACAATGATAATTTTAATACGTATGTAAATGATCGAATGAAGGGACAAGCAATATACGATATTATGCAAGG
GATTGACTATGATATACAGTCTTACTTAATTGAGGCTCGTAAAGAAGCGAATGAAACGATGTGGTATGGAAAAGTAGATG
GGTTTATTAATGAAATAAATCGTATTGCTCTTCTAAATGAAGTAACACCAGAAAATAAGTGGCTCGTTAATAATGGAATT
TACTTTGCTAGTCGTTTAGGGAAGTTTCATAGCAATCCAAATAAAGGATTAGAAGTTGTGACACAGGCAATGCATATGTA
TCCACGTTTAAGTGAGCCGTATTTTGTCGCAGTAGAACAAATTACAACAAATTATAACGGAAAAGATTATAGCGGGAATA
CAGTAGATTTAGAGAAAATACGTAAAGAAGGAAAAGAGCAGTACTTACCAAAAACGTATACATTTGATGATGGATCTATC
GTATTTAAAACAGGAGATAAAGTATCGGAAGAAAAAATTAAGAGACTATACTGGGCTGCAAAGGAAGTAAAAGCGCAGTA
TCATCGTGTAATTGGGAATGATAAAGCGTTAGAGCCGGGCAATGCAGATGATATATTAACGATCGTAATTTATAACAGTC
CAGAAGAGTACCAATTAAATAGACAACTGTATGGATATGAAACGAACAACGGTGGAATTTATATTGAAGAAACAGGAACA
TTCTTTACATATGAACGCACGCCAGAACAAAGTATTTATAGTTTAGAAGAATTATTCCGCCATGAGTTTACCCATTATCT
TCAAGGGAGATATGAAGTGCCAGGTTTATTCGGAAGAGGAGATATGTATCAAAATGAAAGGTTAACTTGGTTCCAAGAAG
GAAATGCAGAGTTTTTCGCAGGGTCTACTCGAACAAATAATGTAGTACCGAGAAAGAGCATCATTAGTGGATTATCATCT
GATCCTGCAAGTCGTTATACAGCAGAGCGTACATTATTTGCTAAATACGGTTCTTGGGATTTCTATAATTACTCGTTCGC
ATTGCAGTCTTACTTATATACGCATCAGTTTGAAACATTTGATAAAATTCAAGATTTGATTCGTGCGAATGACGTGAAAA
ATTATGATGCATATCGTGAAAATCTAAGTAAAGATCCTAAGTTAAATAAAGAGTATCAAGAGTATATGCAGCAGCTAATC
GATAATCAAGATAAATATAATGTACCGGCAGTAGCGGATGATTATTTAGCTGAACATGCCCCAAAATCATTAACAGCAGT
AGAGAAAGAAATGACTGAAACGTTGCCGATGAAAGATGCAAAAATGACAAAACATAGCTCCCAATTCTTTAATACATTTA
CATTAGAAGGTACGTATACAGGTAGTGTAACAAAAGGTGAGTCAGAAGATTGGAACGCAATGAGTAAGAAAGTAAATGAA
GTTTTGGAACAACTTGCGCAAAAAGAATGGAGTGGCTACAAAACTGTTACAGCATATTTCGTCAATTATCGTGTAAATAG
CTCAAATGAATTTGAATATGATGTAGTCTTCCACGGTATCGCAAAAGATGACGGAGAAAATAAAGCTCCAACGGTTAATA
TAAATGGCCCTTATAATGGACTTGTAAAAGAAGGTATTCAATTTAAAAGTGACGGCTCAAAAGATGAAGATGGAAAAATC
GTTTCATATTTATGGGATTTTGGAGATGGAAGAACAAGTACAGAAGTAAATCCAGTACATGTATATGAAAGAGAAGGTTC
ATATAAAGTAGCGTTAATAGTAAAAGATGATAAAGGGAAAGAGAGCAAAAGCGAAACAACGGTTACGGTTAAAGATGGAA
GTTTAACAGAATCAGAACCAAATAATCGCCCGGAGGAAGCAAATCGTATTGGACTAAACACTACGATAAAAGGTAGCCTT
ATCGGCGGGGATCACACTGATGTTTATACATTTAATGTAGCATCAGCGAAAGATATCGATATTTCCGTTTTAAATGAGTA
TGGAATCGGGATGACATGGGTACTTCACCATGAATCAGATATGCAAAATTATGCTGCTTACGGTCAAGCAAATGGCAATC
ATATAGAGGCAAACTTTAATGCAAAACCAGGTGAATATTACTTGTATGTATATAAATATGATAATGGCGATGGAACTTAC
AAATTATCAGTAAAATAA

Upstream 100 bases:

>100_bases
AAATGTAAGAAGAAATAATATGAAATATTGCATTTTATATTGTTGTATCTAGATTTTATGTTAAATTCTTGGATGGAATA
TTAAAATAGGGGGCAAGGAT

Downstream 100 bases:

>100_bases
GTGCTTTTCCAATGTATGTTTAACTTTACTTTTTGTGGAAAATAGTATATTATATAGATATATAATATATCGGTTATTTA
CTAGGAGGAGCCTGTCACAA

Product: microbial collagenase metalloprotease, peptidase m9a family

Products: NA

Alternate protein names: 120 kDa collagenase [H]

Number of amino acids: Translated: 965; Mature: 965

Protein sequence:

>965_residues
MNKKSKINKVMLSISTMALSLGALQAPASAEEKVPYNVLKTKPVGIEKPVDEIGHVSKAEETLSFQERLKVGDFSQRPAS
IPNKAAVKQVKESYSMADLNKMNDQELVETLGCIKWHQITDLFQFNEDAKAFYKDKGKMQVIIDELAHRGSTFTRDDSKG
IQTFTEVLRSAFYLAFYNNELSELNERSFQDKCLPALKAIAKNPNFKLGTAEQDTVVSAYGKLISNASSDVETVQYASNI
LKQYNDNFNTYVNDRMKGQAIYDIMQGIDYDIQSYLIEARKEANETMWYGKVDGFINEINRIALLNEVTPENKWLVNNGI
YFASRLGKFHSNPNKGLEVVTQAMHMYPRLSEPYFVAVEQITTNYNGKDYSGNTVDLEKIRKEGKEQYLPKTYTFDDGSI
VFKTGDKVSEEKIKRLYWAAKEVKAQYHRVIGNDKALEPGNADDILTIVIYNSPEEYQLNRQLYGYETNNGGIYIEETGT
FFTYERTPEQSIYSLEELFRHEFTHYLQGRYEVPGLFGRGDMYQNERLTWFQEGNAEFFAGSTRTNNVVPRKSIISGLSS
DPASRYTAERTLFAKYGSWDFYNYSFALQSYLYTHQFETFDKIQDLIRANDVKNYDAYRENLSKDPKLNKEYQEYMQQLI
DNQDKYNVPAVADDYLAEHAPKSLTAVEKEMTETLPMKDAKMTKHSSQFFNTFTLEGTYTGSVTKGESEDWNAMSKKVNE
VLEQLAQKEWSGYKTVTAYFVNYRVNSSNEFEYDVVFHGIAKDDGENKAPTVNINGPYNGLVKEGIQFKSDGSKDEDGKI
VSYLWDFGDGRTSTEVNPVHVYEREGSYKVALIVKDDKGKESKSETTVTVKDGSLTESEPNNRPEEANRIGLNTTIKGSL
IGGDHTDVYTFNVASAKDIDISVLNEYGIGMTWVLHHESDMQNYAAYGQANGNHIEANFNAKPGEYYLYVYKYDNGDGTY
KLSVK

Sequences:

>Translated_965_residues
MNKKSKINKVMLSISTMALSLGALQAPASAEEKVPYNVLKTKPVGIEKPVDEIGHVSKAEETLSFQERLKVGDFSQRPAS
IPNKAAVKQVKESYSMADLNKMNDQELVETLGCIKWHQITDLFQFNEDAKAFYKDKGKMQVIIDELAHRGSTFTRDDSKG
IQTFTEVLRSAFYLAFYNNELSELNERSFQDKCLPALKAIAKNPNFKLGTAEQDTVVSAYGKLISNASSDVETVQYASNI
LKQYNDNFNTYVNDRMKGQAIYDIMQGIDYDIQSYLIEARKEANETMWYGKVDGFINEINRIALLNEVTPENKWLVNNGI
YFASRLGKFHSNPNKGLEVVTQAMHMYPRLSEPYFVAVEQITTNYNGKDYSGNTVDLEKIRKEGKEQYLPKTYTFDDGSI
VFKTGDKVSEEKIKRLYWAAKEVKAQYHRVIGNDKALEPGNADDILTIVIYNSPEEYQLNRQLYGYETNNGGIYIEETGT
FFTYERTPEQSIYSLEELFRHEFTHYLQGRYEVPGLFGRGDMYQNERLTWFQEGNAEFFAGSTRTNNVVPRKSIISGLSS
DPASRYTAERTLFAKYGSWDFYNYSFALQSYLYTHQFETFDKIQDLIRANDVKNYDAYRENLSKDPKLNKEYQEYMQQLI
DNQDKYNVPAVADDYLAEHAPKSLTAVEKEMTETLPMKDAKMTKHSSQFFNTFTLEGTYTGSVTKGESEDWNAMSKKVNE
VLEQLAQKEWSGYKTVTAYFVNYRVNSSNEFEYDVVFHGIAKDDGENKAPTVNINGPYNGLVKEGIQFKSDGSKDEDGKI
VSYLWDFGDGRTSTEVNPVHVYEREGSYKVALIVKDDKGKESKSETTVTVKDGSLTESEPNNRPEEANRIGLNTTIKGSL
IGGDHTDVYTFNVASAKDIDISVLNEYGIGMTWVLHHESDMQNYAAYGQANGNHIEANFNAKPGEYYLYVYKYDNGDGTY
KLSVK
>Mature_965_residues
MNKKSKINKVMLSISTMALSLGALQAPASAEEKVPYNVLKTKPVGIEKPVDEIGHVSKAEETLSFQERLKVGDFSQRPAS
IPNKAAVKQVKESYSMADLNKMNDQELVETLGCIKWHQITDLFQFNEDAKAFYKDKGKMQVIIDELAHRGSTFTRDDSKG
IQTFTEVLRSAFYLAFYNNELSELNERSFQDKCLPALKAIAKNPNFKLGTAEQDTVVSAYGKLISNASSDVETVQYASNI
LKQYNDNFNTYVNDRMKGQAIYDIMQGIDYDIQSYLIEARKEANETMWYGKVDGFINEINRIALLNEVTPENKWLVNNGI
YFASRLGKFHSNPNKGLEVVTQAMHMYPRLSEPYFVAVEQITTNYNGKDYSGNTVDLEKIRKEGKEQYLPKTYTFDDGSI
VFKTGDKVSEEKIKRLYWAAKEVKAQYHRVIGNDKALEPGNADDILTIVIYNSPEEYQLNRQLYGYETNNGGIYIEETGT
FFTYERTPEQSIYSLEELFRHEFTHYLQGRYEVPGLFGRGDMYQNERLTWFQEGNAEFFAGSTRTNNVVPRKSIISGLSS
DPASRYTAERTLFAKYGSWDFYNYSFALQSYLYTHQFETFDKIQDLIRANDVKNYDAYRENLSKDPKLNKEYQEYMQQLI
DNQDKYNVPAVADDYLAEHAPKSLTAVEKEMTETLPMKDAKMTKHSSQFFNTFTLEGTYTGSVTKGESEDWNAMSKKVNE
VLEQLAQKEWSGYKTVTAYFVNYRVNSSNEFEYDVVFHGIAKDDGENKAPTVNINGPYNGLVKEGIQFKSDGSKDEDGKI
VSYLWDFGDGRTSTEVNPVHVYEREGSYKVALIVKDDKGKESKSETTVTVKDGSLTESEPNNRPEEANRIGLNTTIKGSL
IGGDHTDVYTFNVASAKDIDISVLNEYGIGMTWVLHHESDMQNYAAYGQANGNHIEANFNAKPGEYYLYVYKYDNGDGTY
KLSVK

Specific function: Unknown

COG id: COG3291

COG function: function code R; FOG: PKD repeat

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PKD domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013510
- InterPro:   IPR007280
- InterPro:   IPR002169
- InterPro:   IPR013661
- InterPro:   IPR022409
- InterPro:   IPR000601 [H]

Pfam domain/function: PF01752 Peptidase_M9; PF08453 Peptidase_M9_N; PF00801 PKD; PF04151 PPC [H]

EC number: =3.4.24.3 [H]

Molecular weight: Translated: 109958; Mature: 109958

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50093 PKD ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKSKINKVMLSISTMALSLGALQAPASAEEKVPYNVLKTKPVGIEKPVDEIGHVSKAE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEECCCCCCCCCHHHHHCHHHHH
ETLSFQERLKVGDFSQRPASIPNKAAVKQVKESYSMADLNKMNDQELVETLGCIKWHQIT
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHH
DLFQFNEDAKAFYKDKGKMQVIIDELAHRGSTFTRDDSKGIQTFTEVLRSAFYLAFYNNE
HHHHCCCHHHHHHHCCCCEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCH
LSELNERSFQDKCLPALKAIAKNPNFKLGTAEQDTVVSAYGKLISNASSDVETVQYASNI
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
LKQYNDNFNTYVNDRMKGQAIYDIMQGIDYDIQSYLIEARKEANETMWYGKVDGFINEIN
HHHHCCCCCCEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHH
RIALLNEVTPENKWLVNNGIYFASRLGKFHSNPNKGLEVVTQAMHMYPRLSEPYFVAVEQ
HHHEECCCCCCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEE
ITTNYNGKDYSGNTVDLEKIRKEGKEQYLPKTYTFDDGSIVFKTGDKVSEEKIKRLYWAA
HHCCCCCCCCCCCEEEHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHH
KEVKAQYHRVIGNDKALEPGNADDILTIVIYNSPEEYQLNRQLYGYETNNGGIYIEETGT
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHEECCEEEEEEECCCCEEEEECCC
FFTYERTPEQSIYSLEELFRHEFTHYLQGRYEVPGLFGRGDMYQNERLTWFQEGNAEFFA
EEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEE
GSTRTNNVVPRKSIISGLSSDPASRYTAERTLFAKYGSWDFYNYSFALQSYLYTHQFETF
CCCCCCCCCCHHHHHHCCCCCCHHHHHHHHEEEEECCCCCEEEHHHHHHHHHHHHHHHHH
DKIQDLIRANDVKNYDAYRENLSKDPKLNKEYQEYMQQLIDNQDKYNVPAVADDYLAEHA
HHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
PKSLTAVEKEMTETLPMKDAKMTKHSSQFFNTFTLEGTYTGSVTKGESEDWNAMSKKVNE
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
VLEQLAQKEWSGYKTVTAYFVNYRVNSSNEFEYDVVFHGIAKDDGENKAPTVNINGPYNG
HHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEEEEEEECCCCCCCCCCEEEECCCCCH
LVKEGIQFKSDGSKDEDGKIVSYLWDFGDGRTSTEVNPVHVYEREGSYKVALIVKDDKGK
HHHCCCEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCC
ESKSETTVTVKDGSLTESEPNNRPEEANRIGLNTTIKGSLIGGDHTDVYTFNVASAKDID
CCCCCCEEEEECCCCCCCCCCCCCCHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCCCE
ISVLNEYGIGMTWVLHHESDMQNYAAYGQANGNHIEANFNAKPGEYYLYVYKYDNGDGTY
EEEECCCCCCEEEEEECCCCHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEEEECCCCEE
KLSVK
EEEEC
>Mature Secondary Structure
MNKKSKINKVMLSISTMALSLGALQAPASAEEKVPYNVLKTKPVGIEKPVDEIGHVSKAE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEECCCCCCCCCHHHHHCHHHHH
ETLSFQERLKVGDFSQRPASIPNKAAVKQVKESYSMADLNKMNDQELVETLGCIKWHQIT
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHHH
DLFQFNEDAKAFYKDKGKMQVIIDELAHRGSTFTRDDSKGIQTFTEVLRSAFYLAFYNNE
HHHHCCCHHHHHHHCCCCEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEEEEEECCH
LSELNERSFQDKCLPALKAIAKNPNFKLGTAEQDTVVSAYGKLISNASSDVETVQYASNI
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
LKQYNDNFNTYVNDRMKGQAIYDIMQGIDYDIQSYLIEARKEANETMWYGKVDGFINEIN
HHHHCCCCCCEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHH
RIALLNEVTPENKWLVNNGIYFASRLGKFHSNPNKGLEVVTQAMHMYPRLSEPYFVAVEQ
HHHEECCCCCCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEE
ITTNYNGKDYSGNTVDLEKIRKEGKEQYLPKTYTFDDGSIVFKTGDKVSEEKIKRLYWAA
HHCCCCCCCCCCCEEEHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHH
KEVKAQYHRVIGNDKALEPGNADDILTIVIYNSPEEYQLNRQLYGYETNNGGIYIEETGT
HHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHEECCEEEEEEECCCCEEEEECCC
FFTYERTPEQSIYSLEELFRHEFTHYLQGRYEVPGLFGRGDMYQNERLTWFQEGNAEFFA
EEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEE
GSTRTNNVVPRKSIISGLSSDPASRYTAERTLFAKYGSWDFYNYSFALQSYLYTHQFETF
CCCCCCCCCCHHHHHHCCCCCCHHHHHHHHEEEEECCCCCEEEHHHHHHHHHHHHHHHHH
DKIQDLIRANDVKNYDAYRENLSKDPKLNKEYQEYMQQLIDNQDKYNVPAVADDYLAEHA
HHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
PKSLTAVEKEMTETLPMKDAKMTKHSSQFFNTFTLEGTYTGSVTKGESEDWNAMSKKVNE
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCHHHHHHHHHH
VLEQLAQKEWSGYKTVTAYFVNYRVNSSNEFEYDVVFHGIAKDDGENKAPTVNINGPYNG
HHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEEEEEEECCCCCCCCCCEEEECCCCCH
LVKEGIQFKSDGSKDEDGKIVSYLWDFGDGRTSTEVNPVHVYEREGSYKVALIVKDDKGK
HHHCCCEECCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCEEEEEEEECCCCC
ESKSETTVTVKDGSLTESEPNNRPEEANRIGLNTTIKGSLIGGDHTDVYTFNVASAKDID
CCCCCCEEEEECCCCCCCCCCCCCCHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCCCE
ISVLNEYGIGMTWVLHHESDMQNYAAYGQANGNHIEANFNAKPGEYYLYVYKYDNGDGTY
EEEECCCCCCEEEEEECCCCHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEEEECCCCEE
KLSVK
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8282691; 11792842 [H]