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The map label for this gene is ykoW [H]

Identifier: 222094300

GI number: 222094300

Start: 594050

End: 596119

Strand: Direct

Name: ykoW [H]

Synonym: BCQ_0614

Alternate gene names: 222094300

Gene position: 594050-596119 (Clockwise)

Preceding gene: 222094299

Following gene: 222094302

Centisome position: 11.39

GC content: 30.34

Gene sequence:

>2070_bases
ATGAAGGAACAATATAGTAATCAAAATACCTTTTTAAGTATGATAGATATGGATTTAATAAGAAGAGGATTATTACATGC
TATTCAAGATTTAGTATTTATTGTTAAAGTTATTGATGATGAAACATTTACATATATTTATGTAAATAAGTTAGGTATGG
ATTATGCGAAGCTAAGTGAAGAATGTTATGGAAAAACTTTTGCAGAAGTATTACCGGAAGATACGGCGGAAATATTGCAA
GTGCAATATGCAAAAGTAGCGAGCGAAGCGAAAGCACATACCTTTTGTGATGTAGTTAGTTTACCAACTGGTAATTTACA
TTATGAATCTTCACTTAATCCTGTATTTGATGAAGAAGGAGTATGTCAGTTTATTATTTGTATTACAAGGGATATCACAG
CTCAAATAGAGGAGAAGATGGAGATAGAGGAAAAACAAATGCTGTTTAAGTCATTACTAGAATATAATAATGACTCCATC
ATATCTATAGATTCTATAGGAAGAATTACATATGCAAATCCAGCAACGTATGAAATATTTGGATACCGATTTGAAGAATT
AAATAATAAGTTTATTTTTGAATTTATTAATAAAGAATATGAAAAAGATTTTCAAATTATATTTAAAGAAGCCATGCAAG
GAAGGGCAAAGCAAATTGTTTCAAAGAAATATGTTCATAAAGAAGGGTACGAGCTCTATATTTCCTTGAGAACTATCCCG
ATTATTGTAAATGGTGAAATTGTTGGAGTATATATTGTTACAAGGGATGTTACAAAGCAAATATTAAATGAAATGAGAAC
GGAATATTTAGCTTATTATGATCAGCTAACAGGATTAATGAATAGAATTTCATGTACAAATAAGTTAAATGATTTTTTAA
ATGAGAAGGTAGCTTTTGCGTTTATCTTTATAGATTTAGATGAATTTCACCTTATTAATGATACGTTTGGTCATAAAGAA
GGAGATAAAGTGTTACAAAAAGTTACAGAATGTTTAAGCAGTTTTCAAATACCCGGTATACACTTATTTAGAGAACACGA
TGATCAATTTGTTATGTTAATAGAAAATATAACGAAAGAACGTGTAGAGGGAGTTTCCAAAAACATACTGAAAAGGATTA
GTGAACATTTTGTAATCGAAGAAGAGGACGTGTATTTAAGTGCTTCAATCGGAATTGTAATGGCTCCAACAGATGGAGAA
GATGAAAAGATATTATTCCAAAGAGTTGATGCTGCTTTGGAAAAAGCAAAAGAAAAAGGAAAAGGGCATTATCATTTTTA
TTGCAGTGGGTTAGATTGTGAGCGTGAACAAAGATTTATAATAGAAAATCAATTACATCGTGCTATAGAAAAAAATGAAT
TCTTCTTATATTATCAGCCGCAAATTAATATTGAAACGAAAAAAATAGCTAGTATGGAGGCTTTAATAAGGTGGGAGAAT
AAAGAATTAGGATTTGTCTCTCCCAATCAATTTATTCCGCTAGCAGAAAGAACAGGATTTATTATTAAGCTTGATGAATG
GGTAGTAAATGAAGTGTGTCGACAAATACGCGAATGGTTAAATAAAGGATATGAAGTTGTCCCAATTGCAGTTAATATTT
CAGCCAGGCATTTTCGCTCTATTACATTAATAGAGATGATTACAAGAGCTTTACATAAGTACAATGTACCAGCTCATTTA
TTAGCGATAGAGGTTACAGAAGGAGCCCTTATACATAAAGATATATCGAAAAGAGTATTGCTACAATTAAAAGAACAAAA
TTTAAAGATTCATTTAGATGATTTTGGTACAGGGTATTCATCTTTGAGTTATTTAAAAACGTATCCAATTGATACTTTGA
AAATTGATCGTTCTTTTATGGAAGGTATACATGTAGATGAACGCGATACGAATATTACGGCTGCAATTATTCATCTAGCT
CATACGTTGGAATTGAATGTAATTGCAGAAGGGGTAGAAAAAGCGGAACAAATACAATTTTTGAAGGAAAAGAATGTGAA
GTTTGTACAAGGTTATTATTATAGCCGCCCTTTATCAAAATATGATGTGGAAAATGTGTATTATAAATAA

Upstream 100 bases:

>100_bases
AAAAATAAAAATAATATGTAATCATACATTTAAAAAAGGATACATATTCATATAAAATGGGATATATGAATAAAAATAGA
TCAGACGGGTTGAGATAAAT

Downstream 100 bases:

>100_bases
TCGATAAAAAAAGTGATGTGCTAAGAAGCACATCACTTTTTATGTGTACCGGGTTTATCATTGTAACCAGATGTAAAAAT
AGCTGTAAGAAATGTGAGTG

Product: sensory box/ggdef family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MKEQYSNQNTFLSMIDMDLIRRGLLHAIQDLVFIVKVIDDETFTYIYVNKLGMDYAKLSEECYGKTFAEVLPEDTAEILQ
VQYAKVASEAKAHTFCDVVSLPTGNLHYESSLNPVFDEEGVCQFIICITRDITAQIEEKMEIEEKQMLFKSLLEYNNDSI
ISIDSIGRITYANPATYEIFGYRFEELNNKFIFEFINKEYEKDFQIIFKEAMQGRAKQIVSKKYVHKEGYELYISLRTIP
IIVNGEIVGVYIVTRDVTKQILNEMRTEYLAYYDQLTGLMNRISCTNKLNDFLNEKVAFAFIFIDLDEFHLINDTFGHKE
GDKVLQKVTECLSSFQIPGIHLFREHDDQFVMLIENITKERVEGVSKNILKRISEHFVIEEEDVYLSASIGIVMAPTDGE
DEKILFQRVDAALEKAKEKGKGHYHFYCSGLDCEREQRFIIENQLHRAIEKNEFFLYYQPQINIETKKIASMEALIRWEN
KELGFVSPNQFIPLAERTGFIIKLDEWVVNEVCRQIREWLNKGYEVVPIAVNISARHFRSITLIEMITRALHKYNVPAHL
LAIEVTEGALIHKDISKRVLLQLKEQNLKIHLDDFGTGYSSLSYLKTYPIDTLKIDRSFMEGIHVDERDTNITAAIIHLA
HTLELNVIAEGVEKAEQIQFLKEKNVKFVQGYYYSRPLSKYDVENVYYK

Sequences:

>Translated_689_residues
MKEQYSNQNTFLSMIDMDLIRRGLLHAIQDLVFIVKVIDDETFTYIYVNKLGMDYAKLSEECYGKTFAEVLPEDTAEILQ
VQYAKVASEAKAHTFCDVVSLPTGNLHYESSLNPVFDEEGVCQFIICITRDITAQIEEKMEIEEKQMLFKSLLEYNNDSI
ISIDSIGRITYANPATYEIFGYRFEELNNKFIFEFINKEYEKDFQIIFKEAMQGRAKQIVSKKYVHKEGYELYISLRTIP
IIVNGEIVGVYIVTRDVTKQILNEMRTEYLAYYDQLTGLMNRISCTNKLNDFLNEKVAFAFIFIDLDEFHLINDTFGHKE
GDKVLQKVTECLSSFQIPGIHLFREHDDQFVMLIENITKERVEGVSKNILKRISEHFVIEEEDVYLSASIGIVMAPTDGE
DEKILFQRVDAALEKAKEKGKGHYHFYCSGLDCEREQRFIIENQLHRAIEKNEFFLYYQPQINIETKKIASMEALIRWEN
KELGFVSPNQFIPLAERTGFIIKLDEWVVNEVCRQIREWLNKGYEVVPIAVNISARHFRSITLIEMITRALHKYNVPAHL
LAIEVTEGALIHKDISKRVLLQLKEQNLKIHLDDFGTGYSSLSYLKTYPIDTLKIDRSFMEGIHVDERDTNITAAIIHLA
HTLELNVIAEGVEKAEQIQFLKEKNVKFVQGYYYSRPLSKYDVENVYYK
>Mature_689_residues
MKEQYSNQNTFLSMIDMDLIRRGLLHAIQDLVFIVKVIDDETFTYIYVNKLGMDYAKLSEECYGKTFAEVLPEDTAEILQ
VQYAKVASEAKAHTFCDVVSLPTGNLHYESSLNPVFDEEGVCQFIICITRDITAQIEEKMEIEEKQMLFKSLLEYNNDSI
ISIDSIGRITYANPATYEIFGYRFEELNNKFIFEFINKEYEKDFQIIFKEAMQGRAKQIVSKKYVHKEGYELYISLRTIP
IIVNGEIVGVYIVTRDVTKQILNEMRTEYLAYYDQLTGLMNRISCTNKLNDFLNEKVAFAFIFIDLDEFHLINDTFGHKE
GDKVLQKVTECLSSFQIPGIHLFREHDDQFVMLIENITKERVEGVSKNILKRISEHFVIEEEDVYLSASIGIVMAPTDGE
DEKILFQRVDAALEKAKEKGKGHYHFYCSGLDCEREQRFIIENQLHRAIEKNEFFLYYQPQINIETKKIASMEALIRWEN
KELGFVSPNQFIPLAERTGFIIKLDEWVVNEVCRQIREWLNKGYEVVPIAVNISARHFRSITLIEMITRALHKYNVPAHL
LAIEVTEGALIHKDISKRVLLQLKEQNLKIHLDDFGTGYSSLSYLKTYPIDTLKIDRSFMEGIHVDERDTNITAAIIHLA
HTLELNVIAEGVEKAEQIQFLKEKNVKFVQGYYYSRPLSKYDVENVYYK

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=445, Percent_Identity=33.2584269662921, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI87081921, Length=423, Percent_Identity=31.9148936170213, Blast_Score=243, Evalue=4e-65,
Organism=Escherichia coli, GI226510982, Length=412, Percent_Identity=28.3980582524272, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=35.5102040816327, Blast_Score=168, Evalue=9e-43,
Organism=Escherichia coli, GI87081845, Length=243, Percent_Identity=37.4485596707819, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=34.1666666666667, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI87081980, Length=255, Percent_Identity=34.9019607843137, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1786507, Length=258, Percent_Identity=32.9457364341085, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1788502, Length=242, Percent_Identity=32.6446280991736, Blast_Score=139, Evalue=8e-34,
Organism=Escherichia coli, GI1788849, Length=442, Percent_Identity=26.0180995475113, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1787055, Length=422, Percent_Identity=25.3554502369668, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788381, Length=370, Percent_Identity=23.2432432432432, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87082096, Length=313, Percent_Identity=25.8785942492013, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI87081881, Length=289, Percent_Identity=29.4117647058824, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1789650, Length=426, Percent_Identity=22.3004694835681, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI87081977, Length=155, Percent_Identity=32.9032258064516, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787262, Length=206, Percent_Identity=25.7281553398058, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI145693134, Length=195, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 80240; Mature: 80240

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50112 PAS ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQYSNQNTFLSMIDMDLIRRGLLHAIQDLVFIVKVIDDETFTYIYVNKLGMDYAKLSE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
ECYGKTFAEVLPEDTAEILQVQYAKVASEAKAHTFCDVVSLPTGNLHYESSLNPVFDEEG
HHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCCCC
VCQFIICITRDITAQIEEKMEIEEKQMLFKSLLEYNNDSIISIDSIGRITYANPATYEIF
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCEEEEE
GYRFEELNNKFIFEFINKEYEKDFQIIFKEAMQGRAKQIVSKKYVHKEGYELYISLRTIP
CEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEE
IIVNGEIVGVYIVTRDVTKQILNEMRTEYLAYYDQLTGLMNRISCTNKLNDFLNEKVAFA
EEECCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
FIFIDLDEFHLINDTFGHKEGDKVLQKVTECLSSFQIPGIHLFREHDDQFVMLIENITKE
EEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHH
RVEGVSKNILKRISEHFVIEEEDVYLSASIGIVMAPTDGEDEKILFQRVDAALEKAKEKG
HHHHHHHHHHHHHHHHCEEECCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHHHHHHC
KGHYHFYCSGLDCEREQRFIIENQLHRAIEKNEFFLYYQPQINIETKKIASMEALIRWEN
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHEECC
KELGFVSPNQFIPLAERTGFIIKLDEWVVNEVCRQIREWLNKGYEVVPIAVNISARHFRS
CCCCCCCCCCEEEHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEEECHHHHHH
ITLIEMITRALHKYNVPAHLLAIEVTEGALIHKDISKRVLLQLKEQNLKIHLDDFGTGYS
HHHHHHHHHHHHHCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCH
SLSYLKTYPIDTLKIDRSFMEGIHVDERDTNITAAIIHLAHTLELNVIAEGVEKAEQIQF
HHHHHHHCCCCCEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKEKNVKFVQGYYYSRPLSKYDVENVYYK
HHHCCCEEEECCHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKEQYSNQNTFLSMIDMDLIRRGLLHAIQDLVFIVKVIDDETFTYIYVNKLGMDYAKLSE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
ECYGKTFAEVLPEDTAEILQVQYAKVASEAKAHTFCDVVSLPTGNLHYESSLNPVFDEEG
HHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEECCCCCCCCCCCC
VCQFIICITRDITAQIEEKMEIEEKQMLFKSLLEYNNDSIISIDSIGRITYANPATYEIF
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCEEEEE
GYRFEELNNKFIFEFINKEYEKDFQIIFKEAMQGRAKQIVSKKYVHKEGYELYISLRTIP
CEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEE
IIVNGEIVGVYIVTRDVTKQILNEMRTEYLAYYDQLTGLMNRISCTNKLNDFLNEKVAFA
EEECCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
FIFIDLDEFHLINDTFGHKEGDKVLQKVTECLSSFQIPGIHLFREHDDQFVMLIENITKE
EEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHHH
RVEGVSKNILKRISEHFVIEEEDVYLSASIGIVMAPTDGEDEKILFQRVDAALEKAKEKG
HHHHHHHHHHHHHHHHCEEECCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHHHHHHC
KGHYHFYCSGLDCEREQRFIIENQLHRAIEKNEFFLYYQPQINIETKKIASMEALIRWEN
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHEECC
KELGFVSPNQFIPLAERTGFIIKLDEWVVNEVCRQIREWLNKGYEVVPIAVNISARHFRS
CCCCCCCCCCEEEHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEEECHHHHHH
ITLIEMITRALHKYNVPAHLLAIEVTEGALIHKDISKRVLLQLKEQNLKIHLDDFGTGYS
HHHHHHHHHHHHHCCCCEEEEEEEECCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCH
SLSYLKTYPIDTLKIDRSFMEGIHVDERDTNITAAIIHLAHTLELNVIAEGVEKAEQIQF
HHHHHHHCCCCCEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKEKNVKFVQGYYYSRPLSKYDVENVYYK
HHHCCCEEEECCHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]