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The map label for this gene is glsA [H]

Identifier: 222094235

GI number: 222094235

Start: 524913

End: 525842

Strand: Reverse

Name: glsA [H]

Synonym: BCQ_0528

Alternate gene names: 222094235

Gene position: 525842-524913 (Counterclockwise)

Preceding gene: 222094247

Following gene: 222094234

Centisome position: 10.08

GC content: 35.16

Gene sequence:

>930_bases
ATGCAGTGCATTGAAACAAACAACTTACAACAGTTGTTAGAACAAGTAAAACCATATACGAAAAAAGGAAAGCTTGCTAC
TTATATCCCCGAACTAGGAAATGCCAATCCAGATGATTTAGGGATTGCCATTTTTCATAAAGAAACAGAATACATCCATG
CTGGCAACTCACAAACACTATTCACTCTTCAAAGTATTTCAAAAGTAATTACACTTGCACTTGCCCTTTTAGATCGTGGT
GAAGAATATGTATTTTCTAAAGTTGGAATGGAACCAACCGGTGATCCATTTAATTCTATTATTAAATTAGAAACGACAAG
TCCTTCTAAACCACTTAATCCAATGATTAATGCAGGGGCACTAGCCATTACAAGCATGTTAGAAGGAAAAGATAATGAAG
AAAAAATGGATCGCATTCTTCATTTCGTACGTGAAATAACAGATAATCCTACTATTAATTATTCTTCTAAAGTTGCCAAT
TCAGAATTAGAGACAGCTTACTTAAATCGTTCACTTTGTTACTATATGAAACAAAACGGAATTATTGATTGTGATATCGA
AGAACTGATGGATTTATACACTCGTCAATGTGCAGTTGAGGTAAACTGTATCGATTTAGCGCGTATCGGTTTAATTTTTG
CGATGGATGGATATGATCCATATAAGGAAAAACAAATTATCCCTAAGCATATTACAAAGATTTGTAAAACATTTATGGTT
ACATGCGGTATGTATAACGAGTCTGGTGAATTTGCGATTCGTGTTGGTATTCCCGCAAAAAGTGGTGTAGCTGGTGGCAT
TTTCGGCTGTGTAAAAGGAGAAATGGGCATTGGTATTTTCGGACCAGCTTTAGATGCAAACGGAAATAGTATCGCTGGCT
TTAAAATTCTTGAACTTCTTTCTGCCCAAGAAGGTTGGAGTATTTTTTAA

Upstream 100 bases:

>100_bases
CAACTTTCGTTTTATCATTCCACTTTTTCATGTTATTATTTATTTCCGAGCATATCGGGAAAAGTAAACTTAGTTAATTC
GAAATAGGAGCGTTGGTACT

Downstream 100 bases:

>100_bases
TTGAGAGCTATCCTGCTATACTAGCAGGATTTTTTCATTTCATAAAAACCTTAACTGTATCAACTATCCACGCCCATACA
AAAACCGTGCTGAAAGTTTC

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTLFTLQSISKVITLALALLDRG
EEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLEGKDNEEKMDRILHFVREITDNPTINYSSKVAN
SELETAYLNRSLCYYMKQNGIIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKEKQIIPKHITKICKTFMV
TCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGEMGIGIFGPALDANGNSIAGFKILELLSAQEGWSIF

Sequences:

>Translated_309_residues
MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTLFTLQSISKVITLALALLDRG
EEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLEGKDNEEKMDRILHFVREITDNPTINYSSKVAN
SELETAYLNRSLCYYMKQNGIIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKEKQIIPKHITKICKTFMV
TCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGEMGIGIFGPALDANGNSIAGFKILELLSAQEGWSIF
>Mature_309_residues
MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTLFTLQSISKVITLALALLDRG
EEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLEGKDNEEKMDRILHFVREITDNPTINYSSKVAN
SELETAYLNRSLCYYMKQNGIIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKEKQIIPKHITKICKTFMV
TCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGEMGIGIFGPALDANGNSIAGFKILELLSAQEGWSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=291, Percent_Identity=35.3951890034364, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI20336214, Length=298, Percent_Identity=33.5570469798658, Blast_Score=166, Evalue=3e-41,
Organism=Escherichia coli, GI1787804, Length=301, Percent_Identity=38.8704318936877, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI1786693, Length=311, Percent_Identity=39.5498392282958, Blast_Score=221, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI17507019, Length=298, Percent_Identity=34.8993288590604, Blast_Score=186, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17532727, Length=277, Percent_Identity=36.4620938628159, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI193204073, Length=282, Percent_Identity=32.9787234042553, Blast_Score=158, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI193204075, Length=284, Percent_Identity=32.7464788732394, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=35.4385964912281, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=35.4385964912281, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=35.4385964912281, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=35.4385964912281, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=35.4385964912281, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=35.4385964912281, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=35.4385964912281, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=35.4385964912281, Blast_Score=174, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 34094; Mature: 34094

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTL
CCCCCCCCHHHHHHHHCCCCCCCCEEEECCHHCCCCCCCCEEEEEECCCCEEECCCCCEE
FTLQSISKVITLALALLDRGEEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGA
EEHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHCEEEEEECCCCCCCCCHHCCHH
LAITSMLEGKDNEEKMDRILHFVREITDNPTINYSSKVANSELETAYLNRSLCYYMKQNG
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHEEECCCC
IIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKEKQIIPKHITKICKTFMV
EEECCHHHHHHHHHHHHEEEECHHHHHHEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHH
TCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGEMGIGIFGPALDANGNSIAGFKILELL
HCCCCCCCCCEEEEEECCCCCCCCCCHHHEECCCCCCEEECCCCCCCCCCCHHHHHHHHH
SAQEGWSIF
HCCCCCCCC
>Mature Secondary Structure
MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTL
CCCCCCCCHHHHHHHHCCCCCCCCEEEECCHHCCCCCCCCEEEEEECCCCEEECCCCCEE
FTLQSISKVITLALALLDRGEEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGA
EEHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCHHCEEEEEECCCCCCCCCHHCCHH
LAITSMLEGKDNEEKMDRILHFVREITDNPTINYSSKVANSELETAYLNRSLCYYMKQNG
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHEEECCCC
IIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKEKQIIPKHITKICKTFMV
EEECCHHHHHHHHHHHHEEEECHHHHHHEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHH
TCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGEMGIGIFGPALDANGNSIAGFKILELL
HCCCCCCCCCEEEEEECCCCCCCCCCHHHEECCCCCCEEECCCCCCCCCCCHHHHHHHHH
SAQEGWSIF
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]