Click here to switch to the map view.

The map label for this gene is rocE [H]

Identifier: 222094229

GI number: 222094229

Start: 519813

End: 521234

Strand: Direct

Name: rocE [H]

Synonym: BCQ_0522

Alternate gene names: 222094229

Gene position: 519813-521234 (Clockwise)

Preceding gene: 222094228

Following gene: 222094230

Centisome position: 9.97

GC content: 36.99

Gene sequence:

>1422_bases
ATGATGGATCAAAACCAAGGATTAAAAAGGGAATTGAAAAGCAGACACATATTTATGATTGCACTTGGAGGAGTTATTGG
TACCGGACTTTTTTTAGGATCGGGGTATACAATTCATGAAGCTGGACCTGGAGGAGCGATTGTAGCTTATCTTGTTGGAG
GATTTGTTATGTATTTAACGATGCTCTGTCTCGGAGAATTAGCTGTTGCGATGCCTGACGCAGGATCTTATCAAACGTAT
GCTACAAAGCATATTTCCCCTGCAGCGGGTTATGTAGTCGGATGGATGTCGTGGCTAAACTGGTCGGCTACAATAGGTAT
TGAACTAATTGCAGTTAGTATTTTAATGAAACGCTGGTTTCCTGATGTATCGTCTTGGGTTTGGTGCGTAGTGTTTGCGG
TACTACTTTTTGCTATTAACGCGTTATCTTCAAGAAGTTTTGCAGAAGTTGAATTTTGGTTTGCAAGTATTAAAGTCATT
ACAATCATTGCATTTATTATTTTGGGCGGGGCAGCGATGTTTGGTTTTCTAGATATGAAAGGAAATGAACCAGCACCAAT
GTTCTCTAGTTTTACTGATTATGGTGGATTGTTTCCAAATGGATTATCCGCTATTTTAATTACGATGATTGCTGTTAACT
TTTCCTTCCAAGGAACAGAACTAGTCGGTATTGCAGCAGGTGAGAGTGAAAATCCAGAGAAAACAATTCCGAAGGCAATT
AATAATACAGTTTGGCGTATACTCGTGTTCTTTGTATTATCTATTTTCATTCTTGCAGGATTATTCCCTTGGCAACAGGC
GGGAGTAATAGAAAGTCCATTTGTAGTTGTATTTGATAAAATTGGTATTCCTTATGCAGCCGATATTATCAATTTCGTTA
TTATTACAGCGGTTCTATCCGTTGCGAATTCAGGATTATATGCAACTTCTCGTATGCTATGGTCTATGTCTAATCAAGGA
ATGATTAGTCCGATTTTTGGTAAGTTATCTAAAAATGGTGTTCCTATTTATGCATTGATTGTAAGTACAATTGTAGGTTG
CCTTTCATTACTATCAGGTATTTATGCGGAAGATACAGTTTATTTATGGCTACTTTCTATTGCCGGGTTCGGAGCGATAT
TAGTTTGGGCATCTATTGCTTTATCTAACTTATTAGCTAGAAGGTCATATATAAAGCAGGGCGGAGATGTGAAAGACTTG
AAATTTAAAACACCACTGTATCCATTCGTACCACTGCTTGCATTAGTATTAAATGTAACAGTAATTGTTGGTATGGCCTT
TATTCCAGAACAAAGAATGGCGTTATATTGTGGAATTCCATTTATGATTGTTTGCTTACTGTTTTACCGTGCGACAAGAA
ATAAGGCACATAAAGTAGAACATATTGAAAAGACAGATACAACAGAAGTAGAAAGTTTATAA

Upstream 100 bases:

>100_bases
ATGATATGTATTTTGCACTCTTTAATAATTTATTTTACGATGAAGAATTTTTGAAACGCTTACATTTAATAGGGTTACAA
AGTGAAAAGGGGGGATTTAT

Downstream 100 bases:

>100_bases
TATTGAGTAATTTAGAGACTGTAAAATTGTAAACAGTCTCTTTTTTTGTGAAAATAAAGCTGGAAACATACTATGTATGC
AAAGGGGGATTAGCGATGAA

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MMDQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTY
ATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVSSWVWCVVFAVLLFAINALSSRSFAEVEFWFASIKVI
TIIAFIILGGAAMFGFLDMKGNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQG
MISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDL
KFKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEHIEKTDTTEVESL

Sequences:

>Translated_473_residues
MMDQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTY
ATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVSSWVWCVVFAVLLFAINALSSRSFAEVEFWFASIKVI
TIIAFIILGGAAMFGFLDMKGNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQG
MISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDL
KFKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEHIEKTDTTEVESL
>Mature_473_residues
MMDQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTY
ATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVSSWVWCVVFAVLLFAINALSSRSFAEVEFWFASIKVI
TIIAFIILGGAAMFGFLDMKGNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQG
MISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDL
KFKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEHIEKTDTTEVESL

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081708, Length=464, Percent_Identity=51.7241379310345, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1788480, Length=476, Percent_Identity=40.9663865546218, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1786302, Length=466, Percent_Identity=38.8412017167382, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI48994972, Length=471, Percent_Identity=36.3057324840764, Blast_Score=301, Evalue=7e-83,
Organism=Escherichia coli, GI1786789, Length=454, Percent_Identity=37.0044052863436, Blast_Score=286, Evalue=3e-78,
Organism=Escherichia coli, GI1789017, Length=454, Percent_Identity=36.784140969163, Blast_Score=281, Evalue=8e-77,
Organism=Escherichia coli, GI1786602, Length=458, Percent_Identity=36.2445414847162, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI87081915, Length=474, Percent_Identity=35.0210970464135, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1790653, Length=446, Percent_Identity=36.7713004484305, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI87081869, Length=257, Percent_Identity=28.0155642023346, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082250, Length=447, Percent_Identity=23.9373601789709, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI2367353, Length=350, Percent_Identity=25.7142857142857, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082023, Length=224, Percent_Identity=27.2321428571429, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=442, Percent_Identity=21.4932126696833, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17540018, Length=375, Percent_Identity=22.6666666666667, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=434, Percent_Identity=24.6543778801843, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=434, Percent_Identity=21.889400921659, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324061, Length=499, Percent_Identity=31.2625250501002, Blast_Score=244, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6320772, Length=440, Percent_Identity=34.3181818181818, Blast_Score=243, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6324553, Length=405, Percent_Identity=33.8271604938272, Blast_Score=233, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6320717, Length=417, Percent_Identity=31.4148681055156, Blast_Score=224, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6319824, Length=416, Percent_Identity=31.25, Blast_Score=223, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6324059, Length=429, Percent_Identity=34.032634032634, Blast_Score=220, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6322892, Length=408, Percent_Identity=32.843137254902, Blast_Score=216, Evalue=9e-57,
Organism=Saccharomyces cerevisiae, GI6324990, Length=498, Percent_Identity=30.1204819277108, Blast_Score=213, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6320251, Length=418, Percent_Identity=30.3827751196172, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6319543, Length=418, Percent_Identity=29.9043062200957, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6321629, Length=481, Percent_Identity=28.0665280665281, Blast_Score=200, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6319542, Length=436, Percent_Identity=28.8990825688073, Blast_Score=199, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6321053, Length=423, Percent_Identity=28.6052009456265, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324924, Length=472, Percent_Identity=29.8728813559322, Blast_Score=193, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6322967, Length=516, Percent_Identity=26.5503875968992, Blast_Score=192, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6324981, Length=508, Percent_Identity=29.7244094488189, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319608, Length=433, Percent_Identity=26.0969976905312, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6320364, Length=489, Percent_Identity=24.1308793456033, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24667468, Length=370, Percent_Identity=23.2432432432432, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221512776, Length=436, Percent_Identity=20.6422018348624, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24666159, Length=436, Percent_Identity=20.6422018348624, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51563; Mature: 51563

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLT
CCCCCCCHHHHHHHCEEEEEEHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
MLCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWF
HHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
PDVSSWVWCVVFAVLLFAINALSSRSFAEVEFWFASIKVITIIAFIILGGAAMFGFLDMK
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
GNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHH
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLS
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTV
HHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDLKFKTPLYPFVPLLALVLNVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHH
VIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEHIEKTDTTEVESL
HHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure
MMDQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLT
CCCCCCCHHHHHHHCEEEEEEHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
MLCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWF
HHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
PDVSSWVWCVVFAVLLFAINALSSRSFAEVEFWFASIKVITIIAFIILGGAAMFGFLDMK
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
GNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHH
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLS
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTV
HHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDLKFKTPLYPFVPLLALVLNVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHH
VIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEHIEKTDTTEVESL
HHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704263; 9384377; 8550462; 8867804 [H]