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The map label for this gene is qacR [H]

Identifier: 222094184

GI number: 222094184

Start: 474949

End: 475530

Strand: Direct

Name: qacR [H]

Synonym: BCQ_0477

Alternate gene names: 222094184

Gene position: 474949-475530 (Clockwise)

Preceding gene: 222094183

Following gene: 222094185

Centisome position: 9.11

GC content: 32.82

Gene sequence:

>582_bases
ATGAGAAGAAGTGCAGAAGAGATAAAGAAAGAAATTGCATATAAAGCAGAAAGTCTGTTTTCACAGAAGGGCTATGCAGC
TACATCTATGGAAGAGATTTGTGAAATTACAGAACGAAGTAAAGGAAGTATTTATTATCACTTTAAAAGTAAAGAAGAAT
TATTTTTATTTGTGGTAAAACAGCATACGTATGATTGGCTTGAAAAATGGAATGAAAAAGAGAAGTCGTATAGTACGAAT
ACTGAAAAATTATATGGTCTCGCGGAATATCATGTAGAGGACATACAGCAACCAATTTCAAATGCAATAGAGGAATTCTC
TATGAGCCAAGTTGTAAGTAAAGAGATTTTGGATGAACTATTAGCTTTAACTAGAGAATCATATGTTATGTTTGAGAAAC
TAATTGAAGCAGGCATACAGTCTGGAGAGTTTCGTGAAGATAATACGCGCGATCTTATGTATATTGTGCATGGATTATTA
TCAGGGCTTGGAGTACTTTACTACGAGTTAGATTATAAAGAGTTGAAACGTATTTATAAAAAGGCAATAGATGTATTGTT
AAAAGGAATGGCAGCTGAATAA

Upstream 100 bases:

>100_bases
TTGAGAGTACGTTTTCTTAAATAAGGAATATAGCCTCTTGTAATAGAGGTTTTTAATTTGTTATCATTAGACTGAACGGT
CGGTTTAAAGAGGTGTGAAT

Downstream 100 bases:

>100_bases
TAAGTCAGTTGCTTTTCTATAAAATAAATTAGACCGAACGGTCGGTTTATGAAAGGGGAATGAAAATGAACGCTTTATTT
AAAAACCGAGCATTTATGCT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MRRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWLEKWNEKEKSYSTN
TEKLYGLAEYHVEDIQQPISNAIEEFSMSQVVSKEILDELLALTRESYVMFEKLIEAGIQSGEFREDNTRDLMYIVHGLL
SGLGVLYYELDYKELKRIYKKAIDVLLKGMAAE

Sequences:

>Translated_193_residues
MRRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWLEKWNEKEKSYSTN
TEKLYGLAEYHVEDIQQPISNAIEEFSMSQVVSKEILDELLALTRESYVMFEKLIEAGIQSGEFREDNTRDLMYIVHGLL
SGLGVLYYELDYKELKRIYKKAIDVLLKGMAAE
>Mature_193_residues
MRRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVKQHTYDWLEKWNEKEKSYSTN
TEKLYGLAEYHVEDIQQPISNAIEEFSMSQVVSKEILDELLALTRESYVMFEKLIEAGIQSGEFREDNTRDLMYIVHGLL
SGLGVLYYELDYKELKRIYKKAIDVLLKGMAAE

Specific function: Transcriptional repressor of qacA. Binds to IR1, an unusually long 28 bp operator, which is located downstream from the qacA promoter and overlaps its transcription start site. QacR is induced from its IR1 site by binding to one of many structurally dissi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR013571
- InterPro:   IPR001647 [H]

Pfam domain/function: PF08360 TetR_C_5; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22623; Mature: 22623

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVK
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
QHTYDWLEKWNEKEKSYSTNTEKLYGLAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALTRESYVMFEKLIEAGIQSGEFREDNTRDLMYIVHGLLSGLGVLYYELDYKELKRIYK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAIDVLLKGMAAE
HHHHHHHHHHCCC
>Mature Secondary Structure
MRRSAEEIKKEIAYKAESLFSQKGYAATSMEEICEITERSKGSIYYHFKSKEELFLFVVK
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
QHTYDWLEKWNEKEKSYSTNTEKLYGLAEYHVEDIQQPISNAIEEFSMSQVVSKEILDEL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALTRESYVMFEKLIEAGIQSGEFREDNTRDLMYIVHGLLSGLGVLYYELDYKELKRIYK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KAIDVLLKGMAAE
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]