Click here to switch to the map view.

The map label for this gene is dcuB [H]

Identifier: 222094171

GI number: 222094171

Start: 461485

End: 462720

Strand: Reverse

Name: dcuB [H]

Synonym: BCQ_0464

Alternate gene names: 222094171

Gene position: 462720-461485 (Counterclockwise)

Preceding gene: 222094179

Following gene: 222094167

Centisome position: 8.87

GC content: 38.43

Gene sequence:

>1236_bases
ATGGGTGGCGTTGGTATGGCAATACTTGTTTTCGTCTTCCACTTACAACCTACAGCTCCTCCTATTGATGTCATGCTTAT
GATTTTAGCAGTAATTACAGCTGCTGGTGCACTCCAAGCCGCTGGAGGAATGGAATACCTTGTTCATCTGGCTGAGAAAG
CATTACGAAAAAATCCAAAACGCATTACATTCTTTGCTCCAATTGTTACTTATTTATTCACACTTTGTGCGGGAACTGGT
CACGTTGCTTATTCTGTACTTCCTGTTATCGCAGAAGTCTCTCGCGAATCTGGAATTAGACCAGAACGACCAATGTCAAT
TGCCGTAATTGCTTCCCAACAAGCAATTACAGCTAGTCCTATATCAGCTGCAACAGTTGCACTTTTAGCAATGTTAGCTG
ACTATAAAATCACTTTATTAGATATTTTAAAAGTAAGTATCCCTTCTACTTTTATCGCTTGTATGGTAGCTGCATTTGTT
GCTAGCAAAATGGGGAAAGAATTAAATGAAGACCCTGAATACTTAAAACGATTAAAAGAAGGAATGATTCCTAAGATTGA
AGAGAAAAAAGAATTTGTTGGTGTAAAAGGCGCTAAATTATCAGTTATCCTTTTCCTAGCAGGAACTTTTCTTGTCGTAC
TTCTTGGTTCATTTGAAGTACTTCGTCCAGGATGGATAGTTGATGGGAAGTTAGCCCGTCTTTCCATGCCAAACACAATT
GAAATGGTTATGTTAACGATTGCAGCTCTTATTATTATTTTCTGTAAACCAAATGTAGAAAGCATCGTGTCTGGTAACGT
CTTTAAAGCGGGGGCAACAGCAGTTGTTGCTATTTTCGGTATCGCTTGGATGGGAGATACTTTCTTTAACGGAAACTTAA
ATATGATTCAAGGATCAATTCAGCATCTAGTAACAAGTGCGCCATGGCTATTTGCCATCGCATTATTCATTCTATCTATT
TTACTATATAGCCAAGCCGCAACAGTACGTGCTTTAATGCCACTTGGATTATCACTCGGTATTCCACCAGCACTACTAAT
CGCGATGTTCCCTGCAGTAAATGGATATTTCTTCATTCCAAACTACGGAACAATCGTTGCTGCCATTAACTTTGATCGTA
CTGGCACAACTGGCATTGGTAAATATGTTTTAAATCATAGCTTTATGATTCCAGGACTAATCGCAACATTCACTTCTATC
GGAATTGGAATGCTCTTAATATCAATTATGTTTTAA

Upstream 100 bases:

>100_bases
TGAATTTCGGAGGTAGTTTATCATGTTTTGGCTACAATTTCTTACGTTACTACTCTGCATCTTTATTGGCGCACGTCTAG
GCGGAGTTGGTCTAGGGGTA

Downstream 100 bases:

>100_bases
AGAAAAAGCACAAACCTACAAATTTACAGGGTTTGTGCTTTTTTAATCAAACGTTTGTTTAAATATTTTTAGCTGTCCAT
TCTTCCATTATGTTCTTTAA

Product: anaerobic c4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MGGVGMAILVFVFHLQPTAPPIDVMLMILAVITAAGALQAAGGMEYLVHLAEKALRKNPKRITFFAPIVTYLFTLCAGTG
HVAYSVLPVIAEVSRESGIRPERPMSIAVIASQQAITASPISAATVALLAMLADYKITLLDILKVSIPSTFIACMVAAFV
ASKMGKELNEDPEYLKRLKEGMIPKIEEKKEFVGVKGAKLSVILFLAGTFLVVLLGSFEVLRPGWIVDGKLARLSMPNTI
EMVMLTIAALIIIFCKPNVESIVSGNVFKAGATAVVAIFGIAWMGDTFFNGNLNMIQGSIQHLVTSAPWLFAIALFILSI
LLYSQAATVRALMPLGLSLGIPPALLIAMFPAVNGYFFIPNYGTIVAAINFDRTGTTGIGKYVLNHSFMIPGLIATFTSI
GIGMLLISIMF

Sequences:

>Translated_411_residues
MGGVGMAILVFVFHLQPTAPPIDVMLMILAVITAAGALQAAGGMEYLVHLAEKALRKNPKRITFFAPIVTYLFTLCAGTG
HVAYSVLPVIAEVSRESGIRPERPMSIAVIASQQAITASPISAATVALLAMLADYKITLLDILKVSIPSTFIACMVAAFV
ASKMGKELNEDPEYLKRLKEGMIPKIEEKKEFVGVKGAKLSVILFLAGTFLVVLLGSFEVLRPGWIVDGKLARLSMPNTI
EMVMLTIAALIIIFCKPNVESIVSGNVFKAGATAVVAIFGIAWMGDTFFNGNLNMIQGSIQHLVTSAPWLFAIALFILSI
LLYSQAATVRALMPLGLSLGIPPALLIAMFPAVNGYFFIPNYGTIVAAINFDRTGTTGIGKYVLNHSFMIPGLIATFTSI
GIGMLLISIMF
>Mature_410_residues
GGVGMAILVFVFHLQPTAPPIDVMLMILAVITAAGALQAAGGMEYLVHLAEKALRKNPKRITFFAPIVTYLFTLCAGTGH
VAYSVLPVIAEVSRESGIRPERPMSIAVIASQQAITASPISAATVALLAMLADYKITLLDILKVSIPSTFIACMVAAFVA
SKMGKELNEDPEYLKRLKEGMIPKIEEKKEFVGVKGAKLSVILFLAGTFLVVLLGSFEVLRPGWIVDGKLARLSMPNTIE
MVMLTIAALIIIFCKPNVESIVSGNVFKAGATAVVAIFGIAWMGDTFFNGNLNMIQGSIQHLVTSAPWLFAIALFILSIL
LYSQAATVRALMPLGLSLGIPPALLIAMFPAVNGYFFIPNYGTIVAAINFDRTGTTGIGKYVLNHSFMIPGLIATFTSIG
IGMLLISIMF

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=398, Percent_Identity=44.2211055276382, Blast_Score=333, Evalue=9e-93,
Organism=Escherichia coli, GI1790565, Length=412, Percent_Identity=41.9902912621359, Blast_Score=301, Evalue=5e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 43947; Mature: 43815

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGVGMAILVFVFHLQPTAPPIDVMLMILAVITAAGALQAAGGMEYLVHLAEKALRKNPK
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
RITFFAPIVTYLFTLCAGTGHVAYSVLPVIAEVSRESGIRPERPMSIAVIASQQAITASP
EEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCC
ISAATVALLAMLADYKITLLDILKVSIPSTFIACMVAAFVASKMGKELNEDPEYLKRLKE
HHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GMIPKIEEKKEFVGVKGAKLSVILFLAGTFLVVLLGSFEVLRPGWIVDGKLARLSMPNTI
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEECCCEEECCCCCHH
EMVMLTIAALIIIFCKPNVESIVSGNVFKAGATAVVAIFGIAWMGDTFFNGNLNMIQGSI
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEECCCHHHHHHHH
QHLVTSAPWLFAIALFILSILLYSQAATVRALMPLGLSLGIPPALLIAMFPAVNGYFFIP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEC
NYGTIVAAINFDRTGTTGIGKYVLNHSFMIPGLIATFTSIGIGMLLISIMF
CCCEEEEEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GGVGMAILVFVFHLQPTAPPIDVMLMILAVITAAGALQAAGGMEYLVHLAEKALRKNPK
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
RITFFAPIVTYLFTLCAGTGHVAYSVLPVIAEVSRESGIRPERPMSIAVIASQQAITASP
EEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCC
ISAATVALLAMLADYKITLLDILKVSIPSTFIACMVAAFVASKMGKELNEDPEYLKRLKE
HHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
GMIPKIEEKKEFVGVKGAKLSVILFLAGTFLVVLLGSFEVLRPGWIVDGKLARLSMPNTI
CCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCEEECCCEEECCCCCHH
EMVMLTIAALIIIFCKPNVESIVSGNVFKAGATAVVAIFGIAWMGDTFFNGNLNMIQGSI
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEECCCHHHHHHHH
QHLVTSAPWLFAIALFILSILLYSQAATVRALMPLGLSLGIPPALLIAMFPAVNGYFFIP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEC
NYGTIVAAINFDRTGTTGIGKYVLNHSFMIPGLIATFTSIGIGMLLISIMF
CCCEEEEEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]