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The map label for this gene is mtnA [H]

Identifier: 222094124

GI number: 222094124

Start: 406101

End: 407144

Strand: Direct

Name: mtnA [H]

Synonym: BCQ_0417

Alternate gene names: 222094124

Gene position: 406101-407144 (Clockwise)

Preceding gene: 222094123

Following gene: 222094125

Centisome position: 7.79

GC content: 39.37

Gene sequence:

>1044_bases
ATGGAAGAGCAATTAATACCAATCCAGTGGAAAGATGATGCTTTAGTTTTATTAGATCAAACATTATTACCGAATGAGGT
TGTTTATGAATCTTTCAAGACAGCTGAAGGTGTGTGGGATGCCATTCAAGTAATGAAAGTAAGAGGTGCGCCAGCGATTG
GTGTTTCAGCAGCTTACGGTGTGTATTTAGGAGCCAAGGAAGTTACTCAAAATACGGTGGAAGAATTGATAGAGGAAGTA
AAAAAGGTATGTGCATACTTAGCAACATCAAGACCGACAGCAGTAAACTTATTTTGGGCACTTGAAAGAATGGAGGCAGT
CGCGACAGAGAACGCACACTTATCAATCGCCCAGTTGAAAGATAGATTATTAGAAGAGGCAAAAGAGATTCATAGAGAAG
ATGAAGAAATTAACCGTCACATTGGAGAACATGCACTAACATTATTCCATGATGGAATGGGAGTATTAACACATTGTAAT
GCAGGTGCGTTAGCGACGACTAAGTATGGTACTGCGACAGCTCCAATGTACTTAGCGAAAGAAAAAGGATGGGACTTGAA
AATCTATTCAGATGAGACACGTCCTAGATTACAAGGTTCAACGTTAACAGCATTAGAATTGCAGCGAGCGGGAATTGACG
TCACTGTCATTACAGATAATATGGCAGCTATGGTTATGTCACAAGGGAAGATTGATGCGGTAATCGTTGGATGCGACCGT
GTGGCAGCAAATGGTGATATAGCAAATAAAATTGGAACATTAGGCGTATCTATTTTAGCGAAATACTACAACATTCCGTT
TTATGTAGCGGCACCAACGCCGACAATTGACTTAAAAACACGGACAGGAAAAGAAATTCCGATTGAGGAAAGAGATGCTT
CTGAAGTAATTAATCGCTTCGGACAATATTCTGCTCCGAAAGAAAGTAAAGTATATAATCCAGCATTTGATGTCACGCCA
CATGAAAATGTAACAGCGATTATTACGGAAAAAGGCATTGTAAAAGCACCGTTTACGGAAAACTTAAAAAAGCTATTTCA
ATAA

Upstream 100 bases:

>100_bases
GAAATTTATTTTACGAGCGAATCAATATAAAACAGGTACAAGCTTTGTAGAAACGTTAAAAGAACAGTCAATGCACTACG
CGAAGTAAGGGGAGAAGATG

Downstream 100 bases:

>100_bases
GTGGATAGATTTAAAAAGTCAGTCATCATAAGCTTCATACTTAGGGGGATGTATATGTTATTACAAAAAGAGAGAGAAGA
AATTGTAGCGTATGGAAAGA

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi 1; MTR-1-P isomerase 1; S-methyl-5-thioribose-1-phosphate isomerase 1 [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MEEQLIPIQWKDDALVLLDQTLLPNEVVYESFKTAEGVWDAIQVMKVRGAPAIGVSAAYGVYLGAKEVTQNTVEELIEEV
KKVCAYLATSRPTAVNLFWALERMEAVATENAHLSIAQLKDRLLEEAKEIHREDEEINRHIGEHALTLFHDGMGVLTHCN
AGALATTKYGTATAPMYLAKEKGWDLKIYSDETRPRLQGSTLTALELQRAGIDVTVITDNMAAMVMSQGKIDAVIVGCDR
VAANGDIANKIGTLGVSILAKYYNIPFYVAAPTPTIDLKTRTGKEIPIEERDASEVINRFGQYSAPKESKVYNPAFDVTP
HENVTAIITEKGIVKAPFTENLKKLFQ

Sequences:

>Translated_347_residues
MEEQLIPIQWKDDALVLLDQTLLPNEVVYESFKTAEGVWDAIQVMKVRGAPAIGVSAAYGVYLGAKEVTQNTVEELIEEV
KKVCAYLATSRPTAVNLFWALERMEAVATENAHLSIAQLKDRLLEEAKEIHREDEEINRHIGEHALTLFHDGMGVLTHCN
AGALATTKYGTATAPMYLAKEKGWDLKIYSDETRPRLQGSTLTALELQRAGIDVTVITDNMAAMVMSQGKIDAVIVGCDR
VAANGDIANKIGTLGVSILAKYYNIPFYVAAPTPTIDLKTRTGKEIPIEERDASEVINRFGQYSAPKESKVYNPAFDVTP
HENVTAIITEKGIVKAPFTENLKKLFQ
>Mature_347_residues
MEEQLIPIQWKDDALVLLDQTLLPNEVVYESFKTAEGVWDAIQVMKVRGAPAIGVSAAYGVYLGAKEVTQNTVEELIEEV
KKVCAYLATSRPTAVNLFWALERMEAVATENAHLSIAQLKDRLLEEAKEIHREDEEINRHIGEHALTLFHDGMGVLTHCN
AGALATTKYGTATAPMYLAKEKGWDLKIYSDETRPRLQGSTLTALELQRAGIDVTVITDNMAAMVMSQGKIDAVIVGCDR
VAANGDIANKIGTLGVSILAKYYNIPFYVAAPTPTIDLKTRTGKEIPIEERDASEVINRFGQYSAPKESKVYNPAFDVTP
HENVTAIITEKGIVKAPFTENLKKLFQ

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=338, Percent_Identity=40.5325443786982, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI23943880, Length=328, Percent_Identity=37.8048780487805, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17557462, Length=336, Percent_Identity=34.5238095238095, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17557123, Length=270, Percent_Identity=27.037037037037, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325375, Length=393, Percent_Identity=35.1145038167939, Blast_Score=174, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6322878, Length=282, Percent_Identity=26.241134751773, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21357667, Length=362, Percent_Identity=36.4640883977901, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI24651647, Length=362, Percent_Identity=36.4640883977901, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI18543295, Length=219, Percent_Identity=26.9406392694064, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 38250; Mature: 38250

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEQLIPIQWKDDALVLLDQTLLPNEVVYESFKTAEGVWDAIQVMKVRGAPAIGVSAAYG
CCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
VYLGAKEVTQNTVEELIEEVKKVCAYLATSRPTAVNLFWALERMEAVATENAHLSIAQLK
HEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCEEHHHHH
DRLLEEAKEIHREDEEINRHIGEHALTLFHDGMGVLTHCNAGALATTKYGTATAPMYLAK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCEEEEC
EKGWDLKIYSDETRPRLQGSTLTALELQRAGIDVTVITDNMAAMVMSQGKIDAVIVGCDR
CCCCEEEEECCCCCCCCCCCEEEEEEHHHCCCEEEEEECCHHHHHHCCCCEEEEEEECCE
VAANGDIANKIGTLGVSILAKYYNIPFYVAAPTPTIDLKTRTGKEIPIEERDASEVINRF
EECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHH
GQYSAPKESKVYNPAFDVTPHENVTAIITEKGIVKAPFTENLKKLFQ
HCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCHHHHHHHHCC
>Mature Secondary Structure
MEEQLIPIQWKDDALVLLDQTLLPNEVVYESFKTAEGVWDAIQVMKVRGAPAIGVSAAYG
CCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
VYLGAKEVTQNTVEELIEEVKKVCAYLATSRPTAVNLFWALERMEAVATENAHLSIAQLK
HEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCCCEEHHHHH
DRLLEEAKEIHREDEEINRHIGEHALTLFHDGMGVLTHCNAGALATTKYGTATAPMYLAK
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCEEEEC
EKGWDLKIYSDETRPRLQGSTLTALELQRAGIDVTVITDNMAAMVMSQGKIDAVIVGCDR
CCCCEEEEECCCCCCCCCCCEEEEEEHHHCCCEEEEEECCHHHHHHCCCCEEEEEEECCE
VAANGDIANKIGTLGVSILAKYYNIPFYVAAPTPTIDLKTRTGKEIPIEERDASEVINRF
EECCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCCCCCHHHHHHHH
GQYSAPKESKVYNPAFDVTPHENVTAIITEKGIVKAPFTENLKKLFQ
HCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA