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The map label for this gene is glcD [H]

Identifier: 222094100

GI number: 222094100

Start: 376865

End: 379135

Strand: Direct

Name: glcD [H]

Synonym: BCQ_0393

Alternate gene names: 222094100

Gene position: 376865-379135 (Clockwise)

Preceding gene: 222094099

Following gene: 222094101

Centisome position: 7.23

GC content: 28.58

Gene sequence:

>2271_bases
ATGGTTAAAGTTAAATTAATGAATGAATTATCAATTCAAGAATTTTTAGATGAAAATGCTTATGAGTATGAAACAGACAT
ATCTAAATTAGAGATTTATAATTATGATGCTTATGTAACGAAAGGTGATGCAAGGTTTATCATTTTTCCTAGCAGTCAGG
AACAGTTTTCAAATCTTGTCCAACGTTTAAATAGACATCAAATTCCGTATCTTATTAGAGCTTCAGGGACGAATTATTGC
GGATCTGTACAAGCAAGAGAAGAGGATATTATTATCTCTACAATTAAAATACCTTTACATGTAACTAGTGAAACAGAAAG
ATTATTTACGGTACCTGCAAGTATCCGTTTAAAAGAAATTAATGAACGGATTAGCGGGAATCAAAAATTTTATCCTCCAG
ATCCCTCTTCTCATAATATCTGTACTATGGGTGGAACGATAGCCATGAATGCTGGTGGTGCAAAATGTTACATGTATGGT
GTTACTTCAAATTATATTAGAACATTAAAAATGCTCACGCCTAAATTTGGGGAGGTATTATTAGGGTCAAAATACTTATA
CGCATTGTCAAATCAGGCCCTAAAGCACATGGTAATCGGTTCTGAAGGAACGTTAGGAGCGTTTACTGAGTCAGTGATAG
AAACTCAAAACCAACTTGAGTACCATAAAGATTTAGTTTTGAATTTTTTGGATTATCAGCAAGCAATTGAATTTGTGTTT
TATATTATTGAGAATAAACTATTAACTAATTCTATTGATATGTCTACAAATCCATATATCCCAAATAAGTCAAAAGGTGT
AGGGGCAAAATTAATTATTGGAATTGAGCATGATGATGAAGAAACAGTTAATCAAAAAATTACCTACTTAAAAGAGGCTG
TTAGTAAGTTTAATGGAAGGGTAACTGCTGAGGGAAACTTACATGAATTAAGAATAAAAGTTGTTCAAAATAATGTGAAA
CACATATTAGAAAATACAAATAAAAAGAAGTATTTTTTATTTGATACAGTAGTACCAAGAAGTAGGTTAAAAGAAATTAT
TGACTATTTCTTTAGTTTATCACTCAGTTTTGATTTTCCTCTATTAAATACGTATCATGCAGGAGATGGAAATATACATC
CCACAGTTTTTTATGATCCTGAGTCTGAAGAAGAAATGGAAAAATTAGAGTTGTTTCTATTTCTTATTATAAAAAAGGCG
AAAGAATTGGGAGGAGCTATAAGTGGAGAACATGGTATAGGAATTGAGAAAAAACATTTGCAATATATTTTGTCAGCGAA
ATATCAAAATAAAATGTATGAAATGATAAAAGATTATTTTGATCCTAATCATCTTATGAATAAAGGGAAAATGTTTAGTA
ACTTTAATGATAGTCAAAAGTATGTACATCGAATTTCACAGTTAAAAAATACATATCACATAACAGAATGTACTAGTTTA
GATTATGTTAAATACGAACCAGTTAAAGAGGATGGTTTGAAGGATGTAAGTGTGAAAGAGCCATTTGAAGAAGTTAATGA
AAGGCTCAATAAATCAGAATTAACTATTCCATATTACCCCGTTATAAACTTAAAATACTCTTTGGAAGAGTTAGTTAGAT
TAAATATCCCGAGTTTTATGGATAACTTTTATAATTTGGACTCCTTAATTAGAGCAGTTGAGTTTGAAGATTCTAAAACT
ATAGGTGCGAAGACATTAAAAAATGTAGAAGGATATAATCTTGTACCTTTATGTGCATTATTTGATGGGATAAAAGAATA
TACAATTAAAAATGTATTTTTGGAAGAGTTATATACAAGATTTTATTTTTATAAGATAGATGTAAATTTAGAAGAGCCAT
TTGAAATTCTAGAGAATGAAAAGGTAAAAAAATATTTAATTGATTATTATGTATGTTCTAACGGTACATTAATATTAATG
TTTTCAAAAGCTATTGAACACGAGCAATTCCTCTTATTTGATGTTTTTAAGGGTGAGAATTTAGGTGAGTATAATACATT
TACTATTATTTCATTAAAAGAATCCCTGCCATTTTCAATTATTAAATTTAAAAATTGGTTATATATGAATAACGAAAGAT
GTTTAATTGTATTTGATAAAGAAATAGATGAAATAGAGTTAAATAGTTTGAAACCTTTATCACTTTCTATAAGGAGAATA
GAAGATAGAAAAAGCCATTATATCTTTTTGGACGAAAAATTAAGGCAACAAATAAATATACAATCACAAGTTGAAGAGGG
GCTTAAAAATGAATTATTTAAACTGTGTTAG

Upstream 100 bases:

>100_bases
GAGGCTATTCATAATATTGAAGTTGCTGAGGAATTAATAAAAGTGGCTAATAGAGGAGTAATTCCAATAAGCAGTAATAC
AACAAAGGATGAGCCCATTT

Downstream 100 bases:

>100_bases
GTGCGGTCTATGTTTAAGTAATTGTCCACAGTATATTAATAATAGGAACGAACGTGTGACACCAAGATCGATTATGATTC
ATCTATCAAATGGAGATAAA

Product: (s)-2-hydroxy-acid oxidase, subunit d

Products: 2-oxo acid; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 756; Mature: 756

Protein sequence:

>756_residues
MVKVKLMNELSIQEFLDENAYEYETDISKLEIYNYDAYVTKGDARFIIFPSSQEQFSNLVQRLNRHQIPYLIRASGTNYC
GSVQAREEDIIISTIKIPLHVTSETERLFTVPASIRLKEINERISGNQKFYPPDPSSHNICTMGGTIAMNAGGAKCYMYG
VTSNYIRTLKMLTPKFGEVLLGSKYLYALSNQALKHMVIGSEGTLGAFTESVIETQNQLEYHKDLVLNFLDYQQAIEFVF
YIIENKLLTNSIDMSTNPYIPNKSKGVGAKLIIGIEHDDEETVNQKITYLKEAVSKFNGRVTAEGNLHELRIKVVQNNVK
HILENTNKKKYFLFDTVVPRSRLKEIIDYFFSLSLSFDFPLLNTYHAGDGNIHPTVFYDPESEEEMEKLELFLFLIIKKA
KELGGAISGEHGIGIEKKHLQYILSAKYQNKMYEMIKDYFDPNHLMNKGKMFSNFNDSQKYVHRISQLKNTYHITECTSL
DYVKYEPVKEDGLKDVSVKEPFEEVNERLNKSELTIPYYPVINLKYSLEELVRLNIPSFMDNFYNLDSLIRAVEFEDSKT
IGAKTLKNVEGYNLVPLCALFDGIKEYTIKNVFLEELYTRFYFYKIDVNLEEPFEILENEKVKKYLIDYYVCSNGTLILM
FSKAIEHEQFLLFDVFKGENLGEYNTFTIISLKESLPFSIIKFKNWLYMNNERCLIVFDKEIDEIELNSLKPLSLSIRRI
EDRKSHYIFLDEKLRQQINIQSQVEEGLKNELFKLC

Sequences:

>Translated_756_residues
MVKVKLMNELSIQEFLDENAYEYETDISKLEIYNYDAYVTKGDARFIIFPSSQEQFSNLVQRLNRHQIPYLIRASGTNYC
GSVQAREEDIIISTIKIPLHVTSETERLFTVPASIRLKEINERISGNQKFYPPDPSSHNICTMGGTIAMNAGGAKCYMYG
VTSNYIRTLKMLTPKFGEVLLGSKYLYALSNQALKHMVIGSEGTLGAFTESVIETQNQLEYHKDLVLNFLDYQQAIEFVF
YIIENKLLTNSIDMSTNPYIPNKSKGVGAKLIIGIEHDDEETVNQKITYLKEAVSKFNGRVTAEGNLHELRIKVVQNNVK
HILENTNKKKYFLFDTVVPRSRLKEIIDYFFSLSLSFDFPLLNTYHAGDGNIHPTVFYDPESEEEMEKLELFLFLIIKKA
KELGGAISGEHGIGIEKKHLQYILSAKYQNKMYEMIKDYFDPNHLMNKGKMFSNFNDSQKYVHRISQLKNTYHITECTSL
DYVKYEPVKEDGLKDVSVKEPFEEVNERLNKSELTIPYYPVINLKYSLEELVRLNIPSFMDNFYNLDSLIRAVEFEDSKT
IGAKTLKNVEGYNLVPLCALFDGIKEYTIKNVFLEELYTRFYFYKIDVNLEEPFEILENEKVKKYLIDYYVCSNGTLILM
FSKAIEHEQFLLFDVFKGENLGEYNTFTIISLKESLPFSIIKFKNWLYMNNERCLIVFDKEIDEIELNSLKPLSLSIRRI
EDRKSHYIFLDEKLRQQINIQSQVEEGLKNELFKLC
>Mature_756_residues
MVKVKLMNELSIQEFLDENAYEYETDISKLEIYNYDAYVTKGDARFIIFPSSQEQFSNLVQRLNRHQIPYLIRASGTNYC
GSVQAREEDIIISTIKIPLHVTSETERLFTVPASIRLKEINERISGNQKFYPPDPSSHNICTMGGTIAMNAGGAKCYMYG
VTSNYIRTLKMLTPKFGEVLLGSKYLYALSNQALKHMVIGSEGTLGAFTESVIETQNQLEYHKDLVLNFLDYQQAIEFVF
YIIENKLLTNSIDMSTNPYIPNKSKGVGAKLIIGIEHDDEETVNQKITYLKEAVSKFNGRVTAEGNLHELRIKVVQNNVK
HILENTNKKKYFLFDTVVPRSRLKEIIDYFFSLSLSFDFPLLNTYHAGDGNIHPTVFYDPESEEEMEKLELFLFLIIKKA
KELGGAISGEHGIGIEKKHLQYILSAKYQNKMYEMIKDYFDPNHLMNKGKMFSNFNDSQKYVHRISQLKNTYHITECTSL
DYVKYEPVKEDGLKDVSVKEPFEEVNERLNKSELTIPYYPVINLKYSLEELVRLNIPSFMDNFYNLDSLIRAVEFEDSKT
IGAKTLKNVEGYNLVPLCALFDGIKEYTIKNVFLEELYTRFYFYKIDVNLEEPFEILENEKVKKYLIDYYVCSNGTLILM
FSKAIEHEQFLLFDVFKGENLGEYNTFTIISLKESLPFSIIKFKNWLYMNNERCLIVFDKEIDEIELNSLKPLSLSIRRI
EDRKSHYIFLDEKLRQQINIQSQVEEGLKNELFKLC

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=430, Percent_Identity=23.4883720930233, Blast_Score=106, Evalue=8e-23,
Organism=Homo sapiens, GI37595754, Length=454, Percent_Identity=23.1277533039648, Blast_Score=99, Evalue=1e-20,
Organism=Escherichia coli, GI1789351, Length=461, Percent_Identity=26.2472885032538, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71992373, Length=425, Percent_Identity=23.2941176470588, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71992381, Length=426, Percent_Identity=22.5352112676056, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71992392, Length=357, Percent_Identity=22.6890756302521, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.3.15

Molecular weight: Translated: 87925; Mature: 87925

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKVKLMNELSIQEFLDENAYEYETDISKLEIYNYDAYVTKGDARFIIFPSSQEQFSNLV
CEEEEEHHHHHHHHHHCCCCCEECCCCCEEEEEECCEEEECCCEEEEEECCCHHHHHHHH
QRLNRHQIPYLIRASGTNYCGSVQAREEDIIISTIKIPLHVTSETERLFTVPASIRLKEI
HHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCEEEECCCHHHHHHH
NERISGNQKFYPPDPSSHNICTMGGTIAMNAGGAKCYMYGVTSNYIRTLKMLTPKFGEVL
HHHHCCCCCCCCCCCCCCCEEEECCEEEEECCCCEEEEEECCHHHHHHHHHHCCHHHHHH
LGSKYLYALSNQALKHMVIGSEGTLGAFTESVIETQNQLEYHKDLVLNFLDYQQAIEFVF
HCCHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIIENKLLTNSIDMSTNPYIPNKSKGVGAKLIIGIEHDDEETVNQKITYLKEAVSKFNGR
HHHHHHHEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCE
VTAEGNLHELRIKVVQNNVKHILENTNKKKYFLFDTVVPRSRLKEIIDYFFSLSLSFDFP
EEECCCHHHEEHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHEEEEEECCC
LLNTYHAGDGNIHPTVFYDPESEEEMEKLELFLFLIIKKAKELGGAISGEHGIGIEKKHL
CCEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
QYILSAKYQNKMYEMIKDYFDPNHLMNKGKMFSNFNDSQKYVHRISQLKNTYHITECTSL
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCC
DYVKYEPVKEDGLKDVSVKEPFEEVNERLNKSELTIPYYPVINLKYSLEELVRLNIPSFM
CCEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECEEEEEEEECCHHHHHHCCCHHHH
DNFYNLDSLIRAVEFEDSKTIGAKTLKNVEGYNLVPLCALFDGIKEYTIKNVFLEELYTR
HHHHCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHE
FYFYKIDVNLEEPFEILENEKVKKYLIDYYVCSNGTLILMFSKAIEHEQFLLFDVFKGEN
EEEEEEEECCCCHHHHHCCCHHHHHEEEEEEECCCEEEEEEECCCCCCCEEEEEEECCCC
LGEYNTFTIISLKESLPFSIIKFKNWLYMNNERCLIVFDKEIDEIELNSLKPLSLSIRRI
CCCCCEEEEEEECCCCCEEEEEEECEEEECCCEEEEEECCCCCEEECCCCCCCHHHHHHH
EDRKSHYIFLDEKLRQQINIQSQVEEGLKNELFKLC
HCCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVKVKLMNELSIQEFLDENAYEYETDISKLEIYNYDAYVTKGDARFIIFPSSQEQFSNLV
CEEEEEHHHHHHHHHHCCCCCEECCCCCEEEEEECCEEEECCCEEEEEECCCHHHHHHHH
QRLNRHQIPYLIRASGTNYCGSVQAREEDIIISTIKIPLHVTSETERLFTVPASIRLKEI
HHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCEEEECCCHHHHHHH
NERISGNQKFYPPDPSSHNICTMGGTIAMNAGGAKCYMYGVTSNYIRTLKMLTPKFGEVL
HHHHCCCCCCCCCCCCCCCEEEECCEEEEECCCCEEEEEECCHHHHHHHHHHCCHHHHHH
LGSKYLYALSNQALKHMVIGSEGTLGAFTESVIETQNQLEYHKDLVLNFLDYQQAIEFVF
HCCHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIIENKLLTNSIDMSTNPYIPNKSKGVGAKLIIGIEHDDEETVNQKITYLKEAVSKFNGR
HHHHHHHEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCE
VTAEGNLHELRIKVVQNNVKHILENTNKKKYFLFDTVVPRSRLKEIIDYFFSLSLSFDFP
EEECCCHHHEEHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHEEEEEECCC
LLNTYHAGDGNIHPTVFYDPESEEEMEKLELFLFLIIKKAKELGGAISGEHGIGIEKKHL
CCEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
QYILSAKYQNKMYEMIKDYFDPNHLMNKGKMFSNFNDSQKYVHRISQLKNTYHITECTSL
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCC
DYVKYEPVKEDGLKDVSVKEPFEEVNERLNKSELTIPYYPVINLKYSLEELVRLNIPSFM
CCEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCEEECEEEEEEEECCHHHHHHCCCHHHH
DNFYNLDSLIRAVEFEDSKTIGAKTLKNVEGYNLVPLCALFDGIKEYTIKNVFLEELYTR
HHHHCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHE
FYFYKIDVNLEEPFEILENEKVKKYLIDYYVCSNGTLILMFSKAIEHEQFLLFDVFKGEN
EEEEEEEECCCCHHHHHCCCHHHHHEEEEEEECCCEEEEEEECCCCCCCEEEEEEECCCC
LGEYNTFTIISLKESLPFSIIKFKNWLYMNNERCLIVFDKEIDEIELNSLKPLSLSIRRI
CCCCCEEEEEEECCCCCEEEEEEECEEEECCCEEEEEECCCCCEEECCCCCCCHHHHHHH
EDRKSHYIFLDEKLRQQINIQSQVEEGLKNELFKLC
HCCCCCEEEEEHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-hydroxy acid; O2

Specific reaction: (S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]