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The map label for this gene is gabR [H]

Identifier: 222094039

GI number: 222094039

Start: 297521

End: 298933

Strand: Reverse

Name: gabR [H]

Synonym: BCQ_0324

Alternate gene names: 222094039

Gene position: 298933-297521 (Counterclockwise)

Preceding gene: 222094041

Following gene: 222094038

Centisome position: 5.73

GC content: 34.82

Gene sequence:

>1413_bases
ATGCTGTGGATACCTATTGACCGATCGTTAGATATTAGTTTAATTCGACAGGTTTATTACCAAATACGTGAGCGAATATT
AAATGGAGAGCTACAGTCCGGAGAAAAGTTACCATCAACACGGGAATTATCTTCTGAGTTAAACGTATCTAGGAATGTAA
TTTTAGAAGCTTATGATCAATTATTTTCCGAAGGTTTTTTGGTCGCTCGACAGGGAGCAGGAACATTCATTGCTGAGGGG
ACTTATTTAGAACAACGTAAAAAATCAACTCTAATTGATTCTTTATCTTGGTGCGAAGAAATAAACAAAGACAGTAACAT
CATTAATTTTCGTTCAGGGATACCAGCATTAGACTTATTTCCACGCAAGAGATGGGCAAATTTGTCTCACACAATATGGC
ACGAAGCACCCCCTTCTACGTTTGGATACGATATTCCCGAAGGGCGTCCCGAATTAAGAAAGGCTTTATCACGCTATTTA
TTAAAAACAAGAGGAGTTTTTTGTCATCCAGAACAATTAGTGATTACTTCTGGTGCAACTCAAGCTTTAACACTTGTTTC
TAAATTACTTTTATCAACGGGTGATGAAGTAATAATAGAAGATCCTATTACCAATGACATTCAAACAATTTTTAAAAATT
CAGGAGCCTTCCTTTATCCTATACCAGTTGATGATAATGGGATGGATACATCTTTGCTACCTGTAAATAAAAATCCAAAA
TTTATCTTTATTACTCCTTCTCATCAGTTTCCTTTAGGTGGAACATTACCGATTCAACGACGGGTTCAATTGATTAACTA
CTCAAGAAAAACAAATTGCTACCTCATTGAAGATGATTATGACAGTGAATTTCGATATGAAGGCTCACCCGTAAGTTCAT
TACAGGGATTGGATCCCGAGCGTGTTATATATATAGGTTCATTTAGTAAAATTTTATCACCGGCCCTTAGGATGGGATAC
TTAGTTCTTCCCTCACACCTTATTGAAAAATGTCGCAAAGTAAAATGGTTTTCAGATCTACATACACCTTCTTTAAATCA
GCTTGTTCTTGCTAAATTTATTACCGAAGATCATTTGGAACGGCATATTATGAAGATGAAAAAACTCTATAAAAATCGAA
GAAACTTCCTTATCCAGCAATTAAAATTAGCATTCTCAAATAAGATCAATATTTTCGGCTATTCTACAGGATTACACTTG
ATTGTTGAATTCAATCAAGTTCAATTCACAAAAGAATTACTTGAGGAAATTCAACAACTCGAAGTAAAAGTATATCCCGT
GGAAGACCACGCCATTAAAAAAGGAAAACATCATAATCAAATTATTATAGGGTACGGACATTTAACAACTGAAGAAATAA
AAGAAGGGGTGAACAGGCTACAGAGGGCATTATCTTGTATATATTCTTGTTAA

Upstream 100 bases:

>100_bases
AGAACTATTTGATCCAACTATAGCATGCTAAAATGGTTCGTATTAGTACCATTTTAGCCGAATTTTTATGGTACCAATTT
TTGATGAAGGGAGCATTTAT

Downstream 100 bases:

>100_bases
CAAATAGACAGTTTAACCAACTTGACCATATTTTTCTGAAGGTACACTATTTACATGTGAAATCATAATTAAATCAAGGT
GTTTCTTGTTAGATAAACGT

Product: gabr

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MLWIPIDRSLDISLIRQVYYQIRERILNGELQSGEKLPSTRELSSELNVSRNVILEAYDQLFSEGFLVARQGAGTFIAEG
TYLEQRKKSTLIDSLSWCEEINKDSNIINFRSGIPALDLFPRKRWANLSHTIWHEAPPSTFGYDIPEGRPELRKALSRYL
LKTRGVFCHPEQLVITSGATQALTLVSKLLLSTGDEVIIEDPITNDIQTIFKNSGAFLYPIPVDDNGMDTSLLPVNKNPK
FIFITPSHQFPLGGTLPIQRRVQLINYSRKTNCYLIEDDYDSEFRYEGSPVSSLQGLDPERVIYIGSFSKILSPALRMGY
LVLPSHLIEKCRKVKWFSDLHTPSLNQLVLAKFITEDHLERHIMKMKKLYKNRRNFLIQQLKLAFSNKINIFGYSTGLHL
IVEFNQVQFTKELLEEIQQLEVKVYPVEDHAIKKGKHHNQIIIGYGHLTTEEIKEGVNRLQRALSCIYSC

Sequences:

>Translated_470_residues
MLWIPIDRSLDISLIRQVYYQIRERILNGELQSGEKLPSTRELSSELNVSRNVILEAYDQLFSEGFLVARQGAGTFIAEG
TYLEQRKKSTLIDSLSWCEEINKDSNIINFRSGIPALDLFPRKRWANLSHTIWHEAPPSTFGYDIPEGRPELRKALSRYL
LKTRGVFCHPEQLVITSGATQALTLVSKLLLSTGDEVIIEDPITNDIQTIFKNSGAFLYPIPVDDNGMDTSLLPVNKNPK
FIFITPSHQFPLGGTLPIQRRVQLINYSRKTNCYLIEDDYDSEFRYEGSPVSSLQGLDPERVIYIGSFSKILSPALRMGY
LVLPSHLIEKCRKVKWFSDLHTPSLNQLVLAKFITEDHLERHIMKMKKLYKNRRNFLIQQLKLAFSNKINIFGYSTGLHL
IVEFNQVQFTKELLEEIQQLEVKVYPVEDHAIKKGKHHNQIIIGYGHLTTEEIKEGVNRLQRALSCIYSC
>Mature_470_residues
MLWIPIDRSLDISLIRQVYYQIRERILNGELQSGEKLPSTRELSSELNVSRNVILEAYDQLFSEGFLVARQGAGTFIAEG
TYLEQRKKSTLIDSLSWCEEINKDSNIINFRSGIPALDLFPRKRWANLSHTIWHEAPPSTFGYDIPEGRPELRKALSRYL
LKTRGVFCHPEQLVITSGATQALTLVSKLLLSTGDEVIIEDPITNDIQTIFKNSGAFLYPIPVDDNGMDTSLLPVNKNPK
FIFITPSHQFPLGGTLPIQRRVQLINYSRKTNCYLIEDDYDSEFRYEGSPVSSLQGLDPERVIYIGSFSKILSPALRMGY
LVLPSHLIEKCRKVKWFSDLHTPSLNQLVLAKFITEDHLERHIMKMKKLYKNRRNFLIQQLKLAFSNKINIFGYSTGLHL
IVEFNQVQFTKELLEEIQQLEVKVYPVEDHAIKKGKHHNQIIIGYGHLTTEEIKEGVNRLQRALSCIYSC

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=341, Percent_Identity=24.0469208211144, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI33469970, Length=341, Percent_Identity=24.0469208211144, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1790797, Length=466, Percent_Identity=25.1072961373391, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1787710, Length=405, Percent_Identity=26.6666666666667, Blast_Score=133, Evalue=3e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53986; Mature: 53986

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWIPIDRSLDISLIRQVYYQIRERILNGELQSGEKLPSTRELSSELNVSRNVILEAYDQ
CEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHH
LFSEGFLVARQGAGTFIAEGTYLEQRKKSTLIDSLSWCEEINKDSNIINFRSGIPALDLF
HHHCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHCC
PRKRWANLSHTIWHEAPPSTFGYDIPEGRPELRKALSRYLLKTRGVFCHPEQLVITSGAT
CCHHHCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCEEEEECCCH
QALTLVSKLLLSTGDEVIIEDPITNDIQTIFKNSGAFLYPIPVDDNGMDTSLLPVNKNPK
HHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCCC
FIFITPSHQFPLGGTLPIQRRVQLINYSRKTNCYLIEDDYDSEFRYEGSPVSSLQGLDPE
EEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCHHHHCCCCCC
RVIYIGSFSKILSPALRMGYLVLPSHLIEKCRKVKWFSDLHTPSLNQLVLAKFITEDHLE
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RHIMKMKKLYKNRRNFLIQQLKLAFSNKINIFGYSTGLHLIVEFNQVQFTKELLEEIQQL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHC
EVKVYPVEDHAIKKGKHHNQIIIGYGHLTTEEIKEGVNRLQRALSCIYSC
EEEEEECCHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLWIPIDRSLDISLIRQVYYQIRERILNGELQSGEKLPSTRELSSELNVSRNVILEAYDQ
CEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHH
LFSEGFLVARQGAGTFIAEGTYLEQRKKSTLIDSLSWCEEINKDSNIINFRSGIPALDLF
HHHCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHCC
PRKRWANLSHTIWHEAPPSTFGYDIPEGRPELRKALSRYLLKTRGVFCHPEQLVITSGAT
CCHHHCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCEEEEECCCH
QALTLVSKLLLSTGDEVIIEDPITNDIQTIFKNSGAFLYPIPVDDNGMDTSLLPVNKNPK
HHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCCC
FIFITPSHQFPLGGTLPIQRRVQLINYSRKTNCYLIEDDYDSEFRYEGSPVSSLQGLDPE
EEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCEEECCCCHHHHCCCCCC
RVIYIGSFSKILSPALRMGYLVLPSHLIEKCRKVKWFSDLHTPSLNQLVLAKFITEDHLE
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
RHIMKMKKLYKNRRNFLIQQLKLAFSNKINIFGYSTGLHLIVEFNQVQFTKELLEEIQQL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEEHHHHHHHHHHHHHHHC
EVKVYPVEDHAIKKGKHHNQIIIGYGHLTTEEIKEGVNRLQRALSCIYSC
EEEEEECCHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]