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The map label for this gene is galE [C]

Identifier: 222094036

GI number: 222094036

Start: 288320

End: 289264

Strand: Direct

Name: galE [C]

Synonym: BCQ_0317

Alternate gene names: 222094036

Gene position: 288320-289264 (Clockwise)

Preceding gene: 222094031

Following gene: 222094040

Centisome position: 5.53

GC content: 28.78

Gene sequence:

>945_bases
ATGGGGAAGAATAATTATTTAATAGTAGGTGGAAATAGTTTCATTGGTATTAACCTCGCATTAGGTTTATTGAAACAAGG
TCAAAACGTAAAAGTATTTTCCAGGCATATAAATAATTTTCCTCAAAATATTATAAATGAGGTTGAATTTATTAAAGGTG
ATTTAGCAAATGTTGAAGATATATATAAAGCTTTAGTGAATGTGGATATTATTATTTATTTAGCTGCAACGTCTAATGTA
ACAACTTCAATTGAAGATGTTTTCGGAGATATAAACAGTAGCCTTTTTTTTCTTAATTTCATGGAAAGTGCTAAAAATTT
CCCCATTAAAAAAATCGTATTAGCATCTTCTGGAGGCACAGTTTATGGTGAACCAGAATATTTACCTATTGATGAGAAAC
ATCCGTTAAAACCACTTTCTCCTTATGGAATAACAAAAGTGTCGCTTGAAAATTATTTGTACTTTTATAAGAAAAAGTAT
GGAATGGATTATGTTGTATGTAGATATTCTAATCCGTATGGAAAATATCAGAACCCGTTAAAGAAAGTTGGAGCAATAAA
TTGTTTTTTGTATCAGCATCTCAGTAATGAAAAGATTAATATATATGGGAATCCACAAGAAATTATTCGAGATTATATTT
ATATCGATGATTTAGTGGAAGTTACTATACAACTATCGCAATTAAATCACTTGAAATTTTGTGTGTATAATATAGGCAGC
GGAAAGGGTCTCTCTTTAAAACGAATTATAGTAGAATTGGAGAAATTAACGGAAAGAAAAGTGGACTTTATCTGCTATAA
ACAAAAGCAAGAAAACGTTCAAAAAATCATTTTAAATATAGATAGAGTAAGACGAGAATGTAATTGGGAACCGAAAGTGG
ATTTCAAAAGTGGAATTAGATTAAATAAGCTATGGATTGAAGAGTTCTTATATAGTAAAAAATAA

Upstream 100 bases:

>100_bases
GGCATACAATTATAAGAGAAAGAATAATAGAATTGTCCAAGTTCATTTATTTGTATTTACAGGTGTGATAAGTAAAAATC
TTATTACTAGAGAGGATATT

Downstream 100 bases:

>100_bases
TAAGCCATGCCCTACTTCTGTATAAGTAGAGCGTGGTTTATTATTTTATTTCTTTTTTTATTACCCAAAGATCTTGATGT
TCCCACCAAAAACCTTCAGT

Product: udp-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MGKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHINNFPQNIINEVEFIKGDLANVEDIYKALVNVDIIIYLAATSNV
TTSIEDVFGDINSSLFFLNFMESAKNFPIKKIVLASSGGTVYGEPEYLPIDEKHPLKPLSPYGITKVSLENYLYFYKKKY
GMDYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNEKINIYGNPQEIIRDYIYIDDLVEVTIQLSQLNHLKFCVYNIGS
GKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKSGIRLNKLWIEEFLYSKK

Sequences:

>Translated_314_residues
MGKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHINNFPQNIINEVEFIKGDLANVEDIYKALVNVDIIIYLAATSNV
TTSIEDVFGDINSSLFFLNFMESAKNFPIKKIVLASSGGTVYGEPEYLPIDEKHPLKPLSPYGITKVSLENYLYFYKKKY
GMDYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNEKINIYGNPQEIIRDYIYIDDLVEVTIQLSQLNHLKFCVYNIGS
GKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKSGIRLNKLWIEEFLYSKK
>Mature_313_residues
GKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHINNFPQNIINEVEFIKGDLANVEDIYKALVNVDIIIYLAATSNVT
TSIEDVFGDINSSLFFLNFMESAKNFPIKKIVLASSGGTVYGEPEYLPIDEKHPLKPLSPYGITKVSLENYLYFYKKKYG
MDYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNEKINIYGNPQEIIRDYIYIDDLVEVTIQLSQLNHLKFCVYNIGSG
KGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKSGIRLNKLWIEEFLYSKK

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=316, Percent_Identity=25, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI56118217, Length=316, Percent_Identity=25, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI189083684, Length=316, Percent_Identity=25, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI7657641, Length=328, Percent_Identity=24.390243902439, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI42516563, Length=299, Percent_Identity=23.4113712374582, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=23.3532934131737, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788353, Length=340, Percent_Identity=23.8235294117647, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17539532, Length=300, Percent_Identity=23.6666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=326, Percent_Identity=24.8466257668712, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71982038, Length=328, Percent_Identity=24.6951219512195, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=24.4897959183673, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=27.5080906148867, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI19923002, Length=327, Percent_Identity=25.0764525993884, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36233; Mature: 36102

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHINNFPQNIINEVEFIKGDLANVED
CCCCCEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHH
IYKALVNVDIIIYLAATSNVTTSIEDVFGDINSSLFFLNFMESAKNFPIKKIVLASSGGT
HHHHHHCEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEHHHHHCCCCEEEEEEECCCCE
VYGEPEYLPIDEKHPLKPLSPYGITKVSLENYLYFYKKKYGMDYVVCRYSNPYGKYQNPL
EECCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
KKVGAINCFLYQHLSNEKINIYGNPQEIIRDYIYIDDLVEVTIQLSQLNHLKFCVYNIGS
HHHHHHHHEEEHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKSGIR
CCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCE
LNKLWIEEFLYSKK
EHHHHHHHHHHCCC
>Mature Secondary Structure 
GKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHINNFPQNIINEVEFIKGDLANVED
CCCCEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHH
IYKALVNVDIIIYLAATSNVTTSIEDVFGDINSSLFFLNFMESAKNFPIKKIVLASSGGT
HHHHHHCEEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEHHHHHCCCCEEEEEEECCCCE
VYGEPEYLPIDEKHPLKPLSPYGITKVSLENYLYFYKKKYGMDYVVCRYSNPYGKYQNPL
EECCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
KKVGAINCFLYQHLSNEKINIYGNPQEIIRDYIYIDDLVEVTIQLSQLNHLKFCVYNIGS
HHHHHHHHEEEHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GKGLSLKRIIVELEKLTERKVDFICYKQKQENVQKIILNIDRVRRECNWEPKVDFKSGIR
CCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCE
LNKLWIEEFLYSKK
EHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]