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The map label for this gene is gcP [H]

Identifier: 222094020

GI number: 222094020

Start: 258611

End: 259627

Strand: Direct

Name: gcP [H]

Synonym: BCQ_0293

Alternate gene names: 222094020

Gene position: 258611-259627 (Clockwise)

Preceding gene: 222094019

Following gene: 222094022

Centisome position: 4.96

GC content: 39.43

Gene sequence:

>1017_bases
ATGGAAAAAAATACGATTATACTTGGTATTGAAACAAGTTGTGATGAAACAGCAGTAGCGGTTGTTAAAAATGGAACGGA
AATTATTGCGAATGTTGTTGCATCACAAATTGAAAGTCATAAACGTTTTGGCGGAGTTGTACCAGAGATTGCGTCCCGTC
ATCATGTAGAAGAAATTACAGTTGTATTAGAAGAAGCGTTAAAAGAAGCGAATATCACATTTGATGATATTGATGCAATT
GCTGTCACAGAAGGACCTGGTTTAGTAGGAGCGCTTCTAATAGGGGTAAATGCAGCGAAAGCAGTAGCTTTTGCACATGA
TATCCCTCTAGTTGGCGTTCATCATATCGCTGGCCACATTTATGCGAACCGTTTAGTAAAAGAAGTTCAATTCCCATTAC
TATCACTTGTTGTATCTGGTGGACATACAGAGCTTGTTTATATGAAAGAACATGGTTCATTTGAAGTAATTGGTGAAACG
CGAGATGATGCAGCAGGAGAGGCATATGATAAAGTAGCTCGTACGTTATCTATGCCATATCCAGGTGGTCCTCATATTGA
TCGACTTGCACATGAAGGAGAACCAACAATTGATTTACCTCGTGCATGGCTAGAACCAGATTCGTATGATTTCAGTTTTA
GCGGATTGAAATCAGCAGTTATCAACACTGTGCATAACGCAAAACAACGCGGGATAGAAATTGCACCAGAAGATTTAGCA
GCAAGTTTCCAAGAGAGTGTAATTGACGTATTAGTAACGAAAGCATCTCGTGCAGCGGATGCTTATAACGTAAAGCAAGT
GCTTCTTGCTGGTGGAGTAGCTGCAAATAAAGGACTGCGTGCACGTTTAGAAGCAGAATTTGCACAAAAAGAAAATGTAG
AGCTAATTATTCCTCCTCTATCTTTATGTACAGATAATGCAGCAATGATTGCAGCGGCAGGTACAATTGCATATGAACAA
GGAAAACGTGCTACATTAGCTTTAAATGCAAATCCAGGATTAGATATTGAAGCATAG

Upstream 100 bases:

>100_bases
AACAGTTATACAGAAAATACGGATTTCAAAATGGTGGAATTCGTAAACGATACTATGCAGACAATCAGGAAGATGGTCTC
GTAATGTGGGTGAATATATA

Downstream 100 bases:

>100_bases
TTATGCACAAAATTAACCACAGCTTGTGGATAAAACCCATATTATCTGTTGATAATATGGGTTTTATTGTGTATATAAAA
TGTTGATAACTTTTTTGTTA

Product: DNA-binding/iron metalloprotein/ap endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAI
AVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGET
RDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
ASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVELIIPPLSLCTDNAAMIAAAGTIAYEQ
GKRATLALNANPGLDIEA

Sequences:

>Translated_338_residues
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAI
AVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGET
RDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
ASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVELIIPPLSLCTDNAAMIAAAGTIAYEQ
GKRATLALNANPGLDIEA
>Mature_338_residues
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAI
AVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGET
RDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
ASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVELIIPPLSLCTDNAAMIAAAGTIAYEQ
GKRATLALNANPGLDIEA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI8923380, Length=325, Percent_Identity=36.3076923076923, Blast_Score=168, Evalue=5e-42,
Organism=Homo sapiens, GI116812636, Length=333, Percent_Identity=33.3333333333333, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI1789445, Length=328, Percent_Identity=43.9024390243902, Blast_Score=281, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI17557464, Length=325, Percent_Identity=32.3076923076923, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=326, Percent_Identity=32.5153374233129, Blast_Score=147, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6320099, Length=351, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6322891, Length=351, Percent_Identity=30.7692307692308, Blast_Score=139, Evalue=9e-34,
Organism=Drosophila melanogaster, GI20129063, Length=361, Percent_Identity=31.3019390581717, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI21357207, Length=329, Percent_Identity=31.6109422492401, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 35944; Mature: 35944

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEIT
CCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHI
HHHHHHHHHCCCCHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
YANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPY
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCC
PGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
CCCCCHHHHHCCCCCCEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHH
ASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVELIIPPL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECCH
SLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
HHHCCCCEEEEEECHHEECCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEIT
CCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHI
HHHHHHHHHCCCCHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
YANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPY
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCC
PGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
CCCCCHHHHHCCCCCCEECCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHH
ASFQESVIDVLVTKASRAADAYNVKQVLLAGGVAANKGLRARLEAEFAQKENVELIIPPL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECCH
SLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
HHHCCCCEEEEEECHHEECCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA