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The map label for this gene is uvsE [H]

Identifier: 222094008

GI number: 222094008

Start: 242189

End: 243151

Strand: Direct

Name: uvsE [H]

Synonym: BCQ_0264

Alternate gene names: 222094008

Gene position: 242189-243151 (Clockwise)

Preceding gene: 222094007

Following gene: 222094010

Centisome position: 4.64

GC content: 35.62

Gene sequence:

>963_bases
ATGCTTGTAAGGCTTGGCTATGTCGCGATGAGTGTACATTTGAAAAACGCATCTCCATCTCAAACGATGACGTACGCGCA
GTTTCAAAAAATAGATGATCGGGAAGCGGCGATTCGTAAACTTGAAAGAATTGCTAATTCGAATTTGGAAAACTGTTTAC
GATTATTAAAGCATAATAAAGGACATGACATATCGTTCTTTCGACTTAGTTCCAAGCTGATTCCTTTAGCGAATCATGAG
GAGTTGTTAGATTGGAATTATATTCGCCCTTTAAAAGAAAATTTAAAAGTGCTAGGTGATTACGCTATTCGAATGAATAT
GCGTATTGATTTTCATCCAGATCATTTTGTTGTACTTAATTCACCCGAGGAGAATATTTTTAAACAATCTGTCAAGACAT
TACAAATGCATAGAAAATTATTAAAAGGTATGGGAATTGAACATAAGCAACGATGTGTAATGCATGTTGGGGGCGGATAT
AAAGATAAAGAGCTCGCATTAGAGCGTTTTATAGAGAATTGGTCTAACGTCCCAAGAGGTATTCAGGAAATGATTATGTT
AGAAAATGATGATACAACTTTTACGCTCGAGGACACATTATATTTAGGAGAAAAGTTGGACATTCCCGTTGTATTTGATT
TACATCATCATATGATGAATCATGATCGAGAAGATTGGCATGAAGATTGGGCGCGTGTTGTACATACGTGGAAATCGTCT
TTGTTACCGGTGAAAATGCACATTTCTAGTCCTAGAGAGGGAAAAGACCCAAGGGCACATGCAGACTTTATTAATGTAGA
TACTTTTTTATCTTTTTTAAAAAAGATAAAAGGAAGTGTTCCGCAAATTGATTGTATGATTGAAGCGAAGAAGAAGGATG
AGTCTTTATTTCAACTCATGAGAGATTTAAGTGAACAAACAGATGTGGAAATTGTCGATGGTGCGAGCTTTTATATTAAA
TGA

Upstream 100 bases:

>100_bases
TTAATAATGAAAAAAGAGAATGCCCTTTGCCGGCATTCTCTTTTTTTATTTTTGTAATTGTACATACTACATAATAACTT
ATGTAGAAATGAGGTGCCGC

Downstream 100 bases:

>100_bases
GCTCTGCACCATCGAGTTTTTTTATTAATAGAGGAGTGCAAATACCACCAATGATCAATCCTGTTAAATGGCTGATAGGG
TTGGCAGAGGGATTGAAGAA

Product: uv damage endonuclease

Products: NA

Alternate protein names: UV-endonuclease; UVED [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MLVRLGYVAMSVHLKNASPSQTMTYAQFQKIDDREAAIRKLERIANSNLENCLRLLKHNKGHDISFFRLSSKLIPLANHE
ELLDWNYIRPLKENLKVLGDYAIRMNMRIDFHPDHFVVLNSPEENIFKQSVKTLQMHRKLLKGMGIEHKQRCVMHVGGGY
KDKELALERFIENWSNVPRGIQEMIMLENDDTTFTLEDTLYLGEKLDIPVVFDLHHHMMNHDREDWHEDWARVVHTWKSS
LLPVKMHISSPREGKDPRAHADFINVDTFLSFLKKIKGSVPQIDCMIEAKKKDESLFQLMRDLSEQTDVEIVDGASFYIK

Sequences:

>Translated_320_residues
MLVRLGYVAMSVHLKNASPSQTMTYAQFQKIDDREAAIRKLERIANSNLENCLRLLKHNKGHDISFFRLSSKLIPLANHE
ELLDWNYIRPLKENLKVLGDYAIRMNMRIDFHPDHFVVLNSPEENIFKQSVKTLQMHRKLLKGMGIEHKQRCVMHVGGGY
KDKELALERFIENWSNVPRGIQEMIMLENDDTTFTLEDTLYLGEKLDIPVVFDLHHHMMNHDREDWHEDWARVVHTWKSS
LLPVKMHISSPREGKDPRAHADFINVDTFLSFLKKIKGSVPQIDCMIEAKKKDESLFQLMRDLSEQTDVEIVDGASFYIK
>Mature_320_residues
MLVRLGYVAMSVHLKNASPSQTMTYAQFQKIDDREAAIRKLERIANSNLENCLRLLKHNKGHDISFFRLSSKLIPLANHE
ELLDWNYIRPLKENLKVLGDYAIRMNMRIDFHPDHFVVLNSPEENIFKQSVKTLQMHRKLLKGMGIEHKQRCVMHVGGGY
KDKELALERFIENWSNVPRGIQEMIMLENDDTTFTLEDTLYLGEKLDIPVVFDLHHHMMNHDREDWHEDWARVVHTWKSS
LLPVKMHISSPREGKDPRAHADFINVDTFLSFLKKIKGSVPQIDCMIEAKKKDESLFQLMRDLSEQTDVEIVDGASFYIK

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion [H]

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004601 [H]

Pfam domain/function: PF03851 UvdE [H]

EC number: NA

Molecular weight: Translated: 37435; Mature: 37435

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVRLGYVAMSVHLKNASPSQTMTYAQFQKIDDREAAIRKLERIANSNLENCLRLLKHNK
CEEEEEEEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GHDISFFRLSSKLIPLANHEELLDWNYIRPLKENLKVLGDYAIRMNMRIDFHPDHFVVLN
CCCEEEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCEEEEEEEEEEECCCEEEEEC
SPEENIFKQSVKTLQMHRKLLKGMGIEHKQRCVMHVGGGYKDKELALERFIENWSNVPRG
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHHCCCHH
IQEMIMLENDDTTFTLEDTLYLGEKLDIPVVFDLHHHMMNHDREDWHEDWARVVHTWKSS
HHHHHEEECCCCEEEEECCEEECCCCCCCEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHC
LLPVKMHISSPREGKDPRAHADFINVDTFLSFLKKIKGSVPQIDCMIEAKKKDESLFQLM
CCEEEEEECCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHH
RDLSEQTDVEIVDGASFYIK
HHHHHHCCEEEECCCEEEEC
>Mature Secondary Structure
MLVRLGYVAMSVHLKNASPSQTMTYAQFQKIDDREAAIRKLERIANSNLENCLRLLKHNK
CEEEEEEEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GHDISFFRLSSKLIPLANHEELLDWNYIRPLKENLKVLGDYAIRMNMRIDFHPDHFVVLN
CCCEEEEEECCCCCCCCCCHHHHCCHHHHHHHHHHHHHCCEEEEEEEEEEECCCEEEEEC
SPEENIFKQSVKTLQMHRKLLKGMGIEHKQRCVMHVGGGYKDKELALERFIENWSNVPRG
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHHCCCHH
IQEMIMLENDDTTFTLEDTLYLGEKLDIPVVFDLHHHMMNHDREDWHEDWARVVHTWKSS
HHHHHEEECCCCEEEEECCEEECCCCCCCEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHC
LLPVKMHISSPREGKDPRAHADFINVDTFLSFLKKIKGSVPQIDCMIEAKKKDESLFQLM
CCEEEEEECCCCCCCCCCCCCCEECHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHH
RDLSEQTDVEIVDGASFYIK
HHHHHHCCEEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]