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The map label for this gene is ykvZ [H]

Identifier: 222093979

GI number: 222093979

Start: 209700

End: 210677

Strand: Direct

Name: ykvZ [H]

Synonym: BCQ_0235

Alternate gene names: 222093979

Gene position: 209700-210677 (Clockwise)

Preceding gene: 222093977

Following gene: 222093980

Centisome position: 4.02

GC content: 35.79

Gene sequence:

>978_bases
ATGGCTAATATTAAAGATATTGCAAAGATGGCGGGAGTTTCAGTTACGACTGTTTCGAGAGTATTGAATGATCATCCGTA
TGTAAGTGAAGAAAAAAGGAAAGCGGTTATAGAGATAGTTGAGAAGTTGAATTACTCACAAAACGCAAATGCTGTTCATT
TATCAAAAGGAAAGACGAATATTGTTGGTGTAATTCTCCCTTACATTAATCACCCGAGCTTCGATGCAATGGTAGGGGGA
ATGATGGAGGGAGCGTTAACTCATAACTACAGGGTGCTACTTTGCCAAACAAACTATAATAAAAAAGAAGAAATGAAAAG
TTTACATATGTTAAAAACGAAACAATTAGATGGCCTTATTATTTGTTCACGTGCAAATGATTGGGAAATGATAGAACCGT
ATGCTTCATACGGCACAATCATTGCTTGTGAAGACAATGATATTTCAAATATCTCAAGTGTATATACAAATCATTCGGCA
GCTTTCCAGCTAGGAATGAATCACCTTATTGAAAAAGGTTATAAAAAAATTGGTTATTGCACGGGGAGAAAGCTAGGACC
GAGTAGTCAAAAGCGTTTTGATGTGTATAAGCGTCAATTGCAATCTATAGATGAAGAAGTGAATGAAGAATGGATTTTCA
CAGAATGTTTTACGTTAGAAGATGGTGTGAGAGTGGCTCATAAATTAAAGGAGATGCAGCATCTTCCTGAAGCATTAATA
GTAGCAGGAGATGAAGTTGCGATTGGGGTTATGACAGAAGCTGAAAAATTAGGTATTCAAGTTCCTGAGGATTTAGCGAT
TATTGGCTTTGATAATCAACCTATCTCGCAAGTGTTACAACTTACAACTATTGATCAAAATTTAAAGGAAATAGGTAAAA
AAGCCTTTGAAATGTTTTATCGGCAAACAAATGCTGAAAGTTCTAAACAAGAAAAGGTGGAAATTCCATATGAACTTGTG
GAGCGATCTACAGTGTAG

Upstream 100 bases:

>100_bases
GAAAATTACACTTTTGTAAGAAAAATGAATGAAGGTGTAATGATGAGAAGGTTTGACATATGTTCATGGAATTTATTAAT
TTAAAAGTAGAGGTGAATGT

Downstream 100 bases:

>100_bases
TTTTAATCCGTTATGTGTATAAGTGCATAACGGATTACTTTTTTGAAATACCTTTGACAGGAAACGCGTTTCATACTTTA
TAAAGGGGTTAAACCGGTTT

Product: sugar-binding transcriptional regulator, laci family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MANIKDIAKMAGVSVTTVSRVLNDHPYVSEEKRKAVIEIVEKLNYSQNANAVHLSKGKTNIVGVILPYINHPSFDAMVGG
MMEGALTHNYRVLLCQTNYNKKEEMKSLHMLKTKQLDGLIICSRANDWEMIEPYASYGTIIACEDNDISNISSVYTNHSA
AFQLGMNHLIEKGYKKIGYCTGRKLGPSSQKRFDVYKRQLQSIDEEVNEEWIFTECFTLEDGVRVAHKLKEMQHLPEALI
VAGDEVAIGVMTEAEKLGIQVPEDLAIIGFDNQPISQVLQLTTIDQNLKEIGKKAFEMFYRQTNAESSKQEKVEIPYELV
ERSTV

Sequences:

>Translated_325_residues
MANIKDIAKMAGVSVTTVSRVLNDHPYVSEEKRKAVIEIVEKLNYSQNANAVHLSKGKTNIVGVILPYINHPSFDAMVGG
MMEGALTHNYRVLLCQTNYNKKEEMKSLHMLKTKQLDGLIICSRANDWEMIEPYASYGTIIACEDNDISNISSVYTNHSA
AFQLGMNHLIEKGYKKIGYCTGRKLGPSSQKRFDVYKRQLQSIDEEVNEEWIFTECFTLEDGVRVAHKLKEMQHLPEALI
VAGDEVAIGVMTEAEKLGIQVPEDLAIIGFDNQPISQVLQLTTIDQNLKEIGKKAFEMFYRQTNAESSKQEKVEIPYELV
ERSTV
>Mature_324_residues
ANIKDIAKMAGVSVTTVSRVLNDHPYVSEEKRKAVIEIVEKLNYSQNANAVHLSKGKTNIVGVILPYINHPSFDAMVGGM
MEGALTHNYRVLLCQTNYNKKEEMKSLHMLKTKQLDGLIICSRANDWEMIEPYASYGTIIACEDNDISNISSVYTNHSAA
FQLGMNHLIEKGYKKIGYCTGRKLGPSSQKRFDVYKRQLQSIDEEVNEEWIFTECFTLEDGVRVAHKLKEMQHLPEALIV
AGDEVAIGVMTEAEKLGIQVPEDLAIIGFDNQPISQVLQLTTIDQNLKEIGKKAFEMFYRQTNAESSKQEKVEIPYELVE
RSTV

Specific function: Repressor That Binds To The Purf Operator And Coregulates Other Genes For De Novo Purine Nucleotide Synthesis. It Is Involved In Regulation Of Purb, Purc, Purek, Purhd, Purl, Purmn And Guaba Expression. Binds Hypoxanthine And Guanine As Inducers. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=333, Percent_Identity=28.2282282282282, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1790369, Length=310, Percent_Identity=30.6451612903226, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=26.5060240963855, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1787580, Length=320, Percent_Identity=27.8125, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788474, Length=314, Percent_Identity=27.7070063694268, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786540, Length=334, Percent_Identity=25.748502994012, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789202, Length=294, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1789068, Length=281, Percent_Identity=28.4697508896797, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI48994940, Length=322, Percent_Identity=22.9813664596273, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790715, Length=332, Percent_Identity=21.6867469879518, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787906, Length=217, Percent_Identity=23.963133640553, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790689, Length=339, Percent_Identity=22.7138643067847, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786268, Length=325, Percent_Identity=21.2307692307692, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36655; Mature: 36524

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIKDIAKMAGVSVTTVSRVLNDHPYVSEEKRKAVIEIVEKLNYSQNANAVHLSKGKTN
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCC
IVGVILPYINHPSFDAMVGGMMEGALTHNYRVLLCQTNYNKKEEMKSLHMLKTKQLDGLI
EEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEE
ICSRANDWEMIEPYASYGTIIACEDNDISNISSVYTNHSAAFQLGMNHLIEKGYKKIGYC
EEECCCCCCCCCCHHCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
TGRKLGPSSQKRFDVYKRQLQSIDEEVNEEWIFTECFTLEDGVRVAHKLKEMQHLPEALI
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHCCHHEE
VAGDEVAIGVMTEAEKLGIQVPEDLAIIGFDNQPISQVLQLTTIDQNLKEIGKKAFEMFY
EECCCEEEEEEECHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQTNAESSKQEKVEIPYELVERSTV
HHHCCCCCCHHCCCCCHHHHCCCCC
>Mature Secondary Structure 
ANIKDIAKMAGVSVTTVSRVLNDHPYVSEEKRKAVIEIVEKLNYSQNANAVHLSKGKTN
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCC
IVGVILPYINHPSFDAMVGGMMEGALTHNYRVLLCQTNYNKKEEMKSLHMLKTKQLDGLI
EEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEE
ICSRANDWEMIEPYASYGTIIACEDNDISNISSVYTNHSAAFQLGMNHLIEKGYKKIGYC
EEECCCCCCCCCCHHCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
TGRKLGPSSQKRFDVYKRQLQSIDEEVNEEWIFTECFTLEDGVRVAHKLKEMQHLPEALI
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHCCHHEE
VAGDEVAIGVMTEAEKLGIQVPEDLAIIGFDNQPISQVLQLTTIDQNLKEIGKKAFEMFY
EECCCEEEEEEECHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQTNAESSKQEKVEIPYELVERSTV
HHHCCCCCCHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]