BacMap

Definition	Bacillus cereus Q1 chromosome, complete genome.
Accession	NC_011969
Length	5,214,195

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The map label for this gene is fabG [H]

Identifier: 222093939

GI number: 222093939

Start: 173576

End: 174349

Strand: Direct

Name: fabG [H]

Synonym: BCQ_0195

Alternate gene names: 222093939

Gene position: 173576-174349 (Clockwise)

Preceding gene: 222093934

Following gene: 222093944

Centisome position: 3.33

GC content: 37.21

Gene sequence:

>774_bases
ATGAATCAATTAAAACATAAAGTAGCAGTTGTTACAGGTGTAAGTCGTTTAGATGGTATAGGCGCAGCAATTTGTAAAGA
ATTAGCTGAAGCAGGATACGATATATTTTTTACGTATTGGACAGAGTATGATAAAGAGATGCCTTGGGGCGTTGATCAAA
GTGAACAAATACAATTACAAGAAGAGTTACTAAAAAACGGTGTGAAAGTATCGAGTATGGAGTTAGATTTAACTCAGAAT
GATGCACCGAAAGAGCTTATAAATAAAGTTACTGAACAACTAGGCTACCCTCATATATTAATTAATAATGCAGCGTATTC
TACGAATAATGATTTCTCTAATTTGACTGCTGAAGAATTAGATAAGCACTACATGGTCAATATTCGTGCGACTACATTAT
TAAGTAGTCAATTTGCCCGAGGGTTTGATAAGAAATCTGGTGGTAGAATTGTGAATATGACTTCGGGACAATTTCAAGGG
CCTATGGTTGGAGAACTAGCGTATGCAACAACGAAGGGGGCTATTGATGCTCTTACTAGTTCGTTGTCAGCCGAGGTAGC
TCATTTAGGAATAACAGTGAATGCAATTAACCCAGGTCCAACTGATACAGGCTGGATGACTGAAGAGATAAAGCGAGGAT
TAAAACCGATGTTTCCATTTGGTAGAATTGGTGAACCAAAGGATGCAGCAAGACTTATTAAGTTTTTAGTAAGTGAAGAA
GCGGAATGGATTACTGGACAAGTTATTCATTCAGAAGGTGGATTCAAAAGGTAA

Upstream 100 bases:

>100_bases
ATTTGGCTTGTGTATCCCCTTTGTAAGGATAGATACCTATGTGGGGAAATTCATATCTCTTATATAAAATATGCGTCCTT
TAAAATTGGAGGAGTATATG

Downstream 100 bases:

>100_bases
AAAGAAGGTATCTCACCCTGGTGAGATACCTTCTTTTTTAATCTTTCTTCAATCTTCGCGCAATACCATTCCCTAAAGAC
TGTAATCCTTGAACGAGGAT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNQLKHKVAVVTGVSRLDGIGAAICKELAEAGYDIFFTYWTEYDKEMPWGVDQSEQIQLQEELLKNGVKVSSMELDLTQN
DAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEELDKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQG
PMVGELAYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWMTEEIKRGLKPMFPFGRIGEPKDAARLIKFLVSEE
AEWITGQVIHSEGGFKR

Sequences:

>Translated_257_residues
MNQLKHKVAVVTGVSRLDGIGAAICKELAEAGYDIFFTYWTEYDKEMPWGVDQSEQIQLQEELLKNGVKVSSMELDLTQN
DAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEELDKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQG
PMVGELAYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWMTEEIKRGLKPMFPFGRIGEPKDAARLIKFLVSEE
AEWITGQVIHSEGGFKR
>Mature_257_residues
MNQLKHKVAVVTGVSRLDGIGAAICKELAEAGYDIFFTYWTEYDKEMPWGVDQSEQIQLQEELLKNGVKVSSMELDLTQN
DAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEELDKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQG
PMVGELAYATTKGAIDALTSSLSAEVAHLGITVNAINPGPTDTGWMTEEIKRGLKPMFPFGRIGEPKDAARLIKFLVSEE
AEWITGQVIHSEGGFKR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=30.1158301158301, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=27.1317829457364, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=26.0377358490566, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI126723750, Length=266, Percent_Identity=27.0676691729323, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=25.4980079681275, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4503301, Length=208, Percent_Identity=25.9615384615385, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI66933014, Length=193, Percent_Identity=28.4974093264249, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=24.8091603053435, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=31.8897637795276, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=30.4347826086957, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87082100, Length=270, Percent_Identity=31.1111111111111, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082160, Length=263, Percent_Identity=28.5171102661597, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI2367365, Length=260, Percent_Identity=27.3076923076923, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=29.9610894941634, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=27.8625954198473, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786812, Length=219, Percent_Identity=26.4840182648402, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=26.7489711934156, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790717, Length=201, Percent_Identity=25.3731343283582, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=259, Percent_Identity=28.1853281853282, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=276, Percent_Identity=29.7101449275362, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17562908, Length=275, Percent_Identity=28.7272727272727, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=277, Percent_Identity=29.6028880866426, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=277, Percent_Identity=27.7978339350181, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=28.2608695652174, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=28.6231884057971, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=276, Percent_Identity=27.536231884058, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=276, Percent_Identity=28.2608695652174, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=268, Percent_Identity=26.865671641791, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=274, Percent_Identity=27.3722627737226, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=26.7206477732794, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=274, Percent_Identity=27.3722627737226, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=262, Percent_Identity=27.4809160305344, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=262, Percent_Identity=27.8625954198473, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=277, Percent_Identity=26.7148014440433, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=29.1512915129151, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=277, Percent_Identity=26.7148014440433, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=263, Percent_Identity=24.7148288973384, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=262, Percent_Identity=27.4809160305344, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=277, Percent_Identity=27.0758122743682, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=26.7441860465116, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17544670, Length=280, Percent_Identity=25.3571428571429, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=194, Percent_Identity=27.319587628866, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=269, Percent_Identity=24.5353159851301, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=282, Percent_Identity=28.0141843971631, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=280, Percent_Identity=27.1428571428571, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=26.6409266409266, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=30.6201550387597, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI23397609, Length=262, Percent_Identity=28.2442748091603, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21355319, Length=265, Percent_Identity=30.5660377358491, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=28.1368821292776, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=271, Percent_Identity=28.0442804428044, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=28.6259541984733, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644337, Length=217, Percent_Identity=29.4930875576037, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 28334; Mature: 28334

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLKHKVAVVTGVSRLDGIGAAICKELAEAGYDIFFTYWTEYDKEMPWGVDQSEQIQLQ
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCCCCHHHHHHH
EELLKNGVKVSSMELDLTQNDAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEEL
HHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHCCCHHHC
DKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQGPMVGELAYATTKGAIDALTS
CCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
SLSAEVAHLGITVNAINPGPTDTGWMTEEIKRGLKPMFPFGRIGEPKDAARLIKFLVSEE
HHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
AEWITGQVIHSEGGFKR
CCHHEEEEEECCCCCCC
>Mature Secondary Structure
MNQLKHKVAVVTGVSRLDGIGAAICKELAEAGYDIFFTYWTEYDKEMPWGVDQSEQIQLQ
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCCCCHHHHHHH
EELLKNGVKVSSMELDLTQNDAPKELINKVTEQLGYPHILINNAAYSTNNDFSNLTAEEL
HHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHCCCHHHC
DKHYMVNIRATTLLSSQFARGFDKKSGGRIVNMTSGQFQGPMVGELAYATTKGAIDALTS
CCEEEEEEHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
SLSAEVAHLGITVNAINPGPTDTGWMTEEIKRGLKPMFPFGRIGEPKDAARLIKFLVSEE
HHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
AEWITGQVIHSEGGFKR
CCHHEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]