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The map label for this gene is mrp [H]

Identifier: 222093917

GI number: 222093917

Start: 141339

End: 142406

Strand: Direct

Name: mrp [H]

Synonym: BCQ_0160

Alternate gene names: 222093917

Gene position: 141339-142406 (Clockwise)

Preceding gene: 222093916

Following gene: 222093919

Centisome position: 2.71

GC content: 39.79

Gene sequence:

>1068_bases
ATGGTAACGAAAGAGCAAGTAGTGGAAGCGTTAGAAGGGATTGTAGATCCGTTTTTACATAAAACGTTAAAAGAAACAGG
GGCAATTAAAGAGGTAACAGTCAAGCCTGAGAAGGAACATGTAAGTGTTAAAATTGCAATCGTAAAAACTGGTACCGCGG
AACAAATGCAATTGCAATCTGGAATTGTAAAGTTAGTAAAAGAACTAGGAGCAGCAACAGTAGGGCTTCGCTTTGCAGAA
TTTACAGAAGAGGAATTAGCTCAGTTTGCACCAGAACAAGAAGAAGAGCAAACTGAATCTTTATTGTCACCAAATTCGAA
AACGACATTTTTAGCAGTGGCGAGTGGAAAAGGTGGAGTAGGGAAATCAACAGTTTCTGTTAACCTTGCTATTGCTTTAG
CTCGTCTAGGGAAAAAAGTTGGTATCATTGATGCTGATATTTATGGTTTTAGCGTACCTGATATGATGGGGATAGAAAAA
CGCCCTGTAGTAAGAGGAGATAAAATCATTCCAGTGGAGCGTCTAGGTGTAAAGGTAATCTCAATGGGATTCTTTGTAGA
AGATAATGCACCGGTCATTTGGAGAGGGCCTATGCTCGGGAAAATGTTAAATCACTTCTTTACGGAAGTAGAGTGGGGCG
ATTTAGATTATTTAGTTTTAGATTTACCACCAGGTACAGGTGATGTTGCGCTAGACTTACATTCGATGTTGCCGGCTTGT
AAAGAGATTATTGTCACAACACCGCATCCAACAGCGGCATTTGTAGCAGCACGTGCTGGAGCAATGGCTTTACGTACAGA
ACATAGTATTCTTGGTGTTGTTGAAAATATGGCTTATTTTGAAAGTAAAACAACTGGCGAAAAAGAATATGTGTTTGGAA
GAGGTGGTGGAGATAAATTAGCTACAGAACTTCAAACAGAAGTACTTGGCCGAATCCCGCTTCAACAACCTGATTGGAAT
AAAGAAGATTTTGCGCCGTCAGTATATGAAGATACGCATACGACAGGTCTTATTTATCGCACAATAGCTGAAGCGGTAAT
TGATAAAACAACTGTTGCGCAAAAATAA

Upstream 100 bases:

>100_bases
ATATGTTATACTGGAAATGTAAACGCATTTATTTCAAAAGTAAAGAGAGATATATTTAATTAACATTATGTTATTTTTCA
TACAGGGGGCTGGGCTAATT

Downstream 100 bases:

>100_bases
AATAATAATGAGTGGATGATACATGTATTGTCCACTCATTATTATCGTTATTATTTTTACTGCTGTTCCTTTTTACCTTC
TTGGGAACCACCTTCACCGC

Product: ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MVTKEQVVEALEGIVDPFLHKTLKETGAIKEVTVKPEKEHVSVKIAIVKTGTAEQMQLQSGIVKLVKELGAATVGLRFAE
FTEEELAQFAPEQEEEQTESLLSPNSKTTFLAVASGKGGVGKSTVSVNLAIALARLGKKVGIIDADIYGFSVPDMMGIEK
RPVVRGDKIIPVERLGVKVISMGFFVEDNAPVIWRGPMLGKMLNHFFTEVEWGDLDYLVLDLPPGTGDVALDLHSMLPAC
KEIIVTTPHPTAAFVAARAGAMALRTEHSILGVVENMAYFESKTTGEKEYVFGRGGGDKLATELQTEVLGRIPLQQPDWN
KEDFAPSVYEDTHTTGLIYRTIAEAVIDKTTVAQK

Sequences:

>Translated_355_residues
MVTKEQVVEALEGIVDPFLHKTLKETGAIKEVTVKPEKEHVSVKIAIVKTGTAEQMQLQSGIVKLVKELGAATVGLRFAE
FTEEELAQFAPEQEEEQTESLLSPNSKTTFLAVASGKGGVGKSTVSVNLAIALARLGKKVGIIDADIYGFSVPDMMGIEK
RPVVRGDKIIPVERLGVKVISMGFFVEDNAPVIWRGPMLGKMLNHFFTEVEWGDLDYLVLDLPPGTGDVALDLHSMLPAC
KEIIVTTPHPTAAFVAARAGAMALRTEHSILGVVENMAYFESKTTGEKEYVFGRGGGDKLATELQTEVLGRIPLQQPDWN
KEDFAPSVYEDTHTTGLIYRTIAEAVIDKTTVAQK
>Mature_355_residues
MVTKEQVVEALEGIVDPFLHKTLKETGAIKEVTVKPEKEHVSVKIAIVKTGTAEQMQLQSGIVKLVKELGAATVGLRFAE
FTEEELAQFAPEQEEEQTESLLSPNSKTTFLAVASGKGGVGKSTVSVNLAIALARLGKKVGIIDADIYGFSVPDMMGIEK
RPVVRGDKIIPVERLGVKVISMGFFVEDNAPVIWRGPMLGKMLNHFFTEVEWGDLDYLVLDLPPGTGDVALDLHSMLPAC
KEIIVTTPHPTAAFVAARAGAMALRTEHSILGVVENMAYFESKTTGEKEYVFGRGGGDKLATELQTEVLGRIPLQQPDWN
KEDFAPSVYEDTHTTGLIYRTIAEAVIDKTTVAQK

Specific function: Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect [H]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=208, Percent_Identity=44.2307692307692, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI6912540, Length=210, Percent_Identity=40, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI118572611, Length=258, Percent_Identity=34.1085271317829, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI87082045, Length=309, Percent_Identity=37.2168284789644, Blast_Score=183, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25143050, Length=213, Percent_Identity=38.0281690140845, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6322188, Length=215, Percent_Identity=35.8139534883721, Blast_Score=142, Evalue=9e-35,
Organism=Saccharomyces cerevisiae, GI6321347, Length=213, Percent_Identity=34.2723004694836, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI221511043, Length=184, Percent_Identity=43.4782608695652, Blast_Score=158, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24667611, Length=213, Percent_Identity=40.8450704225352, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI19921440, Length=221, Percent_Identity=35.7466063348416, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 38593; Mature: 38593

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTKEQVVEALEGIVDPFLHKTLKETGAIKEVTVKPEKEHVSVKIAIVKTGTAEQMQLQS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEEEECCCHHHHHHHH
GIVKLVKELGAATVGLRFAEFTEEELAQFAPEQEEEQTESLLSPNSKTTFLAVASGKGGV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCC
GKSTVSVNLAIALARLGKKVGIIDADIYGFSVPDMMGIEKRPVVRGDKIIPVERLGVKVI
CCCEEEEHHHHHHHHHCCCCCEEECCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHCEEEE
SMGFFVEDNAPVIWRGPMLGKMLNHFFTEVEWGDLDYLVLDLPPGTGDVALDLHSMLPAC
EEEEEEECCCCEEEECHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHH
KEIIVTTPHPTAAFVAARAGAMALRTEHSILGVVENMAYFESKTTGEKEYVFGRGGGDKL
HHHEEECCCCHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHH
ATELQTEVLGRIPLQQPDWNKEDFAPSVYEDTHTTGLIYRTIAEAVIDKTTVAQK
HHHHHHHHHHCCCCCCCCCCCHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVTKEQVVEALEGIVDPFLHKTLKETGAIKEVTVKPEKEHVSVKIAIVKTGTAEQMQLQS
CCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEEEEEEEECCCHHHHHHHH
GIVKLVKELGAATVGLRFAEFTEEELAQFAPEQEEEQTESLLSPNSKTTFLAVASGKGGV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCC
GKSTVSVNLAIALARLGKKVGIIDADIYGFSVPDMMGIEKRPVVRGDKIIPVERLGVKVI
CCCEEEEHHHHHHHHHCCCCCEEECCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHCEEEE
SMGFFVEDNAPVIWRGPMLGKMLNHFFTEVEWGDLDYLVLDLPPGTGDVALDLHSMLPAC
EEEEEEECCCCEEEECHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHH
KEIIVTTPHPTAAFVAARAGAMALRTEHSILGVVENMAYFESKTTGEKEYVFGRGGGDKL
HHHEEECCCCHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHH
ATELQTEVLGRIPLQQPDWNKEDFAPSVYEDTHTTGLIYRTIAEAVIDKTTVAQK
HHHHHHHHHHCCCCCCCCCCCHHCCCCHHCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7559346; 8969501; 9384377; 2517635 [H]