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The map label for this gene is lysS [H]

Identifier: 222093847

GI number: 222093847

Start: 80339

End: 81838

Strand: Direct

Name: lysS [H]

Synonym: BCQ_0086

Alternate gene names: 222093847

Gene position: 80339-81838 (Clockwise)

Preceding gene: 222093846

Following gene: 222093848

Centisome position: 1.54

GC content: 37.2

Gene sequence:

>1500_bases
ATGGATAACATGAACCACGAAGAATTAAACGACCAATTGCTTGTTCGTCGTGAAAAGCTACATAACTTACGTGAGCAAGG
GATCGATCCGTTCGGTAAACGTTTTGAACGTACAAATGCAACAAATGAATTATTAAGCCTATATGGAGAGTTCTCTAAAG
AAGAATTAGAGGAGAAAGAAATCTCTGTTTCTATCGCTGGTCGTATTATGACAAAACGCGGTAAAGGAAAAGCTGGATTT
GCACATATTCAAGATTTACATGGACAAGTTCAAATTTACGTTCGTAAAGATGCTGTTGGAGATGAAGAGTACGAATTATT
TAAAACAGCAGATTTAGGTGACTTAGTAGGTATTGAAGGTAAAGTTTTCAAAACGAACGTTGGAGAACTTTCGGTGAAAG
CAACGGGCTTTACGCTATTAACGAAATCTCTTCGTCCATTACCGGATAAATATCATGGATTAAAAGATGTTGAACAACGC
TACCGTCAACGCTACTTAGACTTAATTACAAGTATGGAAAGCCGTGAAACATTTGTTACTCGCAGTAAAATCATTCGTGA
AATGAGAAGATACTTAGATGACAATGGCTATCTTGAAGTGGAAACACCTATGATGCACGCAATTGCAGGTGGAGCTTCTG
CGCGTCCTTTTATCACGCACCATAATGCGTTAGATATGGAATTATATATGCGTATCGCAATTGAACTTCATTTAAAACGC
CTTATTGTGGGTGGATTAGAAAAAGTTTATGAAATCGGCCGTGTATTCCGTAACGAGGGTGTATCAACTCGTCATAATCC
CGAGTTTACGATGATTGAATTATATGAAGCGTATGCTGATTATAAAGATATTATGAAACTAACAGAAAATATGGTTGCTC
ATATCGCGAAGCAAGTACTAGGTACAACAACAATCCAGTATGGTGATTATGAAATTAATCTAGAACCAGAATGGACACGT
CTTCATATGGTAGATGCAATTAAAGAACATTCTGGAGCAGATTTCTGGAATCCGATGAGTGTAGAAGAAGCGCGTGAACT
TGCAAAAGAACATAATGTAGAAATTAAGGATACAATGGAAGTTGGTCATATTATTAATGAATTCTTCGAGCAAAAAGTAG
AAGATAAATTAATCCAACCAACATTTATTTACGGTCATCCGGTAGAAATTTCGCCACTTGCGAAAAAGAATGACGAAGAT
CCACGATTCACAGATCGTTTCGAATTATTTATCGTTGCACGTGAACATGCAAATGCATTCACTGAATTAAATGATCCAAT
CGATCAGAAAGAACGTTTTGAAGCGCAATTAAAAGAACGCGAACAAGGTAATGATGAAGCTCACATGATGGATGATGATT
ATATCGAAGCTCTTGAGTATGGTATGCCTCCTACAGGTGGACTAGGAATTGGTATTGATCGTCTTGTTATGTTATTAACG
AATGCACCATCTATTCGTGACGTACTATTATTCCCTGCTATGCGTCATAAACAAGACTAA

Upstream 100 bases:

>100_bases
AAGAACTGCCAGTTAGTTGCTGGCAGTTTTTCTAGTTGAGTAGAAAATGCTATACTGTATATATTGTAAAAATTAATAGA
GCTGGAGTGATATCAATACC

Downstream 100 bases:

>100_bases
GCTTTGGAGATTTCTCCAAAGCTTTTTTTATCGCGATTGGTGAGGCTTGATTAAAGTTTCACTTTATTTGAGTATGAGTG
TGGAGATTAGATATTGATGT

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MDNMNHEELNDQLLVRREKLHNLREQGIDPFGKRFERTNATNELLSLYGEFSKEELEEKEISVSIAGRIMTKRGKGKAGF
AHIQDLHGQVQIYVRKDAVGDEEYELFKTADLGDLVGIEGKVFKTNVGELSVKATGFTLLTKSLRPLPDKYHGLKDVEQR
YRQRYLDLITSMESRETFVTRSKIIREMRRYLDDNGYLEVETPMMHAIAGGASARPFITHHNALDMELYMRIAIELHLKR
LIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYKDIMKLTENMVAHIAKQVLGTTTIQYGDYEINLEPEWTR
LHMVDAIKEHSGADFWNPMSVEEARELAKEHNVEIKDTMEVGHIINEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNDED
PRFTDRFELFIVAREHANAFTELNDPIDQKERFEAQLKEREQGNDEAHMMDDDYIEALEYGMPPTGGLGIGIDRLVMLLT
NAPSIRDVLLFPAMRHKQD

Sequences:

>Translated_499_residues
MDNMNHEELNDQLLVRREKLHNLREQGIDPFGKRFERTNATNELLSLYGEFSKEELEEKEISVSIAGRIMTKRGKGKAGF
AHIQDLHGQVQIYVRKDAVGDEEYELFKTADLGDLVGIEGKVFKTNVGELSVKATGFTLLTKSLRPLPDKYHGLKDVEQR
YRQRYLDLITSMESRETFVTRSKIIREMRRYLDDNGYLEVETPMMHAIAGGASARPFITHHNALDMELYMRIAIELHLKR
LIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYKDIMKLTENMVAHIAKQVLGTTTIQYGDYEINLEPEWTR
LHMVDAIKEHSGADFWNPMSVEEARELAKEHNVEIKDTMEVGHIINEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNDED
PRFTDRFELFIVAREHANAFTELNDPIDQKERFEAQLKEREQGNDEAHMMDDDYIEALEYGMPPTGGLGIGIDRLVMLLT
NAPSIRDVLLFPAMRHKQD
>Mature_499_residues
MDNMNHEELNDQLLVRREKLHNLREQGIDPFGKRFERTNATNELLSLYGEFSKEELEEKEISVSIAGRIMTKRGKGKAGF
AHIQDLHGQVQIYVRKDAVGDEEYELFKTADLGDLVGIEGKVFKTNVGELSVKATGFTLLTKSLRPLPDKYHGLKDVEQR
YRQRYLDLITSMESRETFVTRSKIIREMRRYLDDNGYLEVETPMMHAIAGGASARPFITHHNALDMELYMRIAIELHLKR
LIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYKDIMKLTENMVAHIAKQVLGTTTIQYGDYEINLEPEWTR
LHMVDAIKEHSGADFWNPMSVEEARELAKEHNVEIKDTMEVGHIINEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNDED
PRFTDRFELFIVAREHANAFTELNDPIDQKERFEAQLKEREQGNDEAHMMDDDYIEALEYGMPPTGGLGIGIDRLVMLLT
NAPSIRDVLLFPAMRHKQD

Specific function: Unknown

COG id: COG1190

COG function: function code J; Lysyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI194272210, Length=504, Percent_Identity=41.468253968254, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI5031815, Length=504, Percent_Identity=41.468253968254, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI40789249, Length=281, Percent_Identity=24.9110320284698, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI1789256, Length=490, Percent_Identity=52.8571428571429, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI1790571, Length=493, Percent_Identity=52.1298174442191, Blast_Score=527, Evalue=1e-151,
Organism=Escherichia coli, GI87082379, Length=325, Percent_Identity=33.2307692307692, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1788173, Length=296, Percent_Identity=26.3513513513513, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17535925, Length=491, Percent_Identity=46.2321792260692, Blast_Score=428, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17535927, Length=491, Percent_Identity=46.2321792260692, Blast_Score=427, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI71994340, Length=491, Percent_Identity=45.8248472505092, Blast_Score=426, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17551876, Length=508, Percent_Identity=22.0472440944882, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32566633, Length=271, Percent_Identity=23.6162361623616, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320242, Length=510, Percent_Identity=42.9411764705882, Blast_Score=406, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6324256, Length=483, Percent_Identity=32.2981366459627, Blast_Score=210, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6323011, Length=350, Percent_Identity=25.1428571428571, Blast_Score=88, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321807, Length=323, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640851, Length=505, Percent_Identity=41.7821782178218, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24640849, Length=505, Percent_Identity=41.7821782178218, Blast_Score=395, Evalue=1e-110,
Organism=Drosophila melanogaster, GI24584738, Length=258, Percent_Identity=26.3565891472868, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922416, Length=376, Percent_Identity=23.6702127659574, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR002313
- InterPro:   IPR018149
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 57695; Mature: 57695

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNMNHEELNDQLLVRREKLHNLREQGIDPFGKRFERTNATNELLSLYGEFSKEELEEKE
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ISVSIAGRIMTKRGKGKAGFAHIQDLHGQVQIYVRKDAVGDEEYELFKTADLGDLVGIEG
HHHEEHHHHHCCCCCCCCCHHHHHHCCCEEEEEEEECCCCCCHHHHHHCCCCCHHCCCCC
KVFKTNVGELSVKATGFTLLTKSLRPLPDKYHGLKDVEQRYRQRYLDLITSMESRETFVT
EEEEECCCCEEEEECCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSKIIREMRRYLDDNGYLEVETPMMHAIAGGASARPFITHHNALDMELYMRIAIELHLKR
HHHHHHHHHHHHCCCCEEEECCHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
LIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYKDIMKLTENMVAHIAKQVL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTTTIQYGDYEINLEPEWTRLHMVDAIKEHSGADFWNPMSVEEARELAKEHNVEIKDTME
CCCEEEECCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
VGHIINEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNDEDPRFTDRFELFIVAREHANAF
HHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCCCCCCCCCCCCCEEEEEEEEEHHCCHH
TELNDPIDQKERFEAQLKEREQGNDEAHMMDDDYIEALEYGMPPTGGLGIGIDRLVMLLT
HHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
NAPSIRDVLLFPAMRHKQD
CCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDNMNHEELNDQLLVRREKLHNLREQGIDPFGKRFERTNATNELLSLYGEFSKEELEEKE
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ISVSIAGRIMTKRGKGKAGFAHIQDLHGQVQIYVRKDAVGDEEYELFKTADLGDLVGIEG
HHHEEHHHHHCCCCCCCCCHHHHHHCCCEEEEEEEECCCCCCHHHHHHCCCCCHHCCCCC
KVFKTNVGELSVKATGFTLLTKSLRPLPDKYHGLKDVEQRYRQRYLDLITSMESRETFVT
EEEEECCCCEEEEECCHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSKIIREMRRYLDDNGYLEVETPMMHAIAGGASARPFITHHNALDMELYMRIAIELHLKR
HHHHHHHHHHHHCCCCEEEECCHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHH
LIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYKDIMKLTENMVAHIAKQVL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTTTIQYGDYEINLEPEWTRLHMVDAIKEHSGADFWNPMSVEEARELAKEHNVEIKDTME
CCCEEEECCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHH
VGHIINEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNDEDPRFTDRFELFIVAREHANAF
HHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCCCCCCCCCCCCCEEEEEEEEEHHCCHH
TELNDPIDQKERFEAQLKEREQGNDEAHMMDDDYIEALEYGMPPTGGLGIGIDRLVMLLT
HHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
NAPSIRDVLLFPAMRHKQD
CCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA