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The map label for this gene is folB [H]

Identifier: 222093843

GI number: 222093843

Start: 78152

End: 78490

Strand: Direct

Name: folB [H]

Synonym: BCQ_0082

Alternate gene names: 222093843

Gene position: 78152-78490 (Clockwise)

Preceding gene: 222093842

Following gene: 222093844

Centisome position: 1.5

GC content: 36.58

Gene sequence:

>339_bases
ATGGAGTTTTACGGTTATCATGGTGTATTCCCAGAGGAAAATAAATTGGGCCAGAGATTTAAAGTGGACTTAACGGTGGA
ATTGGATTTGAAACAAGCAGGAGAAAGTGATGACTTAGAGCATTCTGTTAATTATGGAGAGCTTTTCGAATTATGTAGGA
AAGTTGTAGAAGATAGAACATATAAGCTTGTAGAGAGTATTGCTGAAAATATTGCTACAGATATATTGAAACAATATGAG
AGTATTTCAAGATGTACGATAAAGGTAATTAAACCAGATCCGCCGATACCAGGACATTATCGTGCTGTAGCGGTAGAAAT
TACGAGAGAACGTCCATGA

Upstream 100 bases:

>100_bases
TCGTGTTCATGATGTGAAGGAAATGGCACGTATGGCTAAGATGATGGATGCGATGATCGGTAAGGGGGTAAAGTAATTGG
ATAAAATTTATATTCATGAT

Downstream 100 bases:

>100_bases
ATAATATAGCTTACATTGCATTAGGTTCAAATATTGGAGAGCGTTATACGTATTTAACTGAAGCGATTCAGTTTCTGAAT
AAAAATCCTTATATCAAAGT

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
MEFYGYHGVFPEENKLGQRFKVDLTVELDLKQAGESDDLEHSVNYGELFELCRKVVEDRTYKLVESIAENIATDILKQYE
SISRCTIKVIKPDPPIPGHYRAVAVEITRERP

Sequences:

>Translated_112_residues
MEFYGYHGVFPEENKLGQRFKVDLTVELDLKQAGESDDLEHSVNYGELFELCRKVVEDRTYKLVESIAENIATDILKQYE
SISRCTIKVIKPDPPIPGHYRAVAVEITRERP
>Mature_112_residues
MEFYGYHGVFPEENKLGQRFKVDLTVELDLKQAGESDDLEHSVNYGELFELCRKVVEDRTYKLVESIAENIATDILKQYE
SISRCTIKVIKPDPPIPGHYRAVAVEITRERP

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 12930; Mature: 12930

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFYGYHGVFPEENKLGQRFKVDLTVELDLKQAGESDDLEHSVNYGELFELCRKVVEDRT
CCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHCCCCCCCHHCCCHHHHHHHHHHHHHHHH
YKLVESIAENIATDILKQYESISRCTIKVIKPDPPIPGHYRAVAVEITRERP
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEEEEEEECCCC
>Mature Secondary Structure
MEFYGYHGVFPEENKLGQRFKVDLTVELDLKQAGESDDLEHSVNYGELFELCRKVVEDRT
CCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHCCCCCCCHHCCCHHHHHHHHHHHHHHHH
YKLVESIAENIATDILKQYESISRCTIKVIKPDPPIPGHYRAVAVEITRERP
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]