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The map label for this gene is dnaX [H]

Identifier: 222093792

GI number: 222093792

Start: 25520

End: 27034

Strand: Direct

Name: dnaX [H]

Synonym: BCQ_0025

Alternate gene names: 222093792

Gene position: 25520-27034 (Clockwise)

Preceding gene: 222093791

Following gene: 222093793

Centisome position: 0.49

GC content: 39.41

Gene sequence:

>1515_bases
GTGTCATACCAAGCGTTATACCGAACATGGAGACCGCAAAAGTTTGAAGATGTAGTCGGTCAAAAGCACGTAACAAAAAC
GTTGCAAAATGCCCTTCTTCAAGAGAAAGTTTCACATGCTTATTTATTTTCTGGGCCGAGGGGAACAGGAAAAACGACAA
TTGCAAAAGTGTTTGCAAAAGCAATTAACTGTGAACATGCTCCGGTAGCTGAACCTTGTAATGAATGCCCTTCTTGTTTG
GGGATTACACAAGGATCTATTTCAGATGTATTAGAAATCGATGCGGCTTCAAATAACGGTGTAGATGAAATTCGAGATAT
TAGAGATAAAGTAAAATATGCTCCAAGTGCTGTAGAATATAAAGTATACATTATTGATGAAGTTCACATGCTTTCTATGG
GTGCCTTCAATGCGCTTTTAAAAACGTTAGAAGAACCGCCAGGACATGTCATCTTTATTTTGGCGACAACAGAACCGCAT
AAGATACCGCCTACAATTATTTCGCGTTGCCAACGTTTCGAATTTCGAAAGATATCAGTAAATGATATTGTTGAGAGATT
ATCGACAGTTGTAAACAATGAAGGTACGCAAGTAGAAGATGAAGCGTTACAAATCGTTGCACGTGCCGCTGAAGGTGGTA
TGCGTGATGCGCTTAGTCTTATTGATCAGGCAATATCTTATAGTGATGAGACTGTTACGACAGAAGATGTATTAGCTGTA
ACAGGGTCTGTTTCTCAGCAATACTTAGGCAACTTAGTAGAATGTATACGTGAAAATGATGTATCAAGAGCATTACGTAT
CATAGATGAGATGATGGGTAAAGGGAAAGATCCAGTTCGCTTTATGGAAGATTTCATTTACTATTATCGTGATATGCTTT
TATATCAAACTTCACCACAACTGGAACATATGTTGGAAAGAGTAATGGTAGATGAGCAATTCCGAATGTTAAGTGAAGAA
ATGCAACCGGAAGTAATCTATGAAATTATTCATACTCTTAGTAAGGGACAGCAGGAAATGAAGTGGACAAACCATCCGCG
AATTTTCTTAGAAGTTGTTATGGTACAACTGTGTCAACAGTTCATGATGCAAGCAAATGGTGCAGATCGTTTACAAGCAA
TTATGAACAGGATGCAGCAATTGGAGAAAGAGTTAGAACAAGTCAAGAAGAATGGTGTGCCGGTTGGTGTGCCGCAGGAA
GTTAGAGAGACGCGTGCAGCACCAAAGCCAGTACGGACAGGAAGTATGAAGATTCCTGTTGGACGCGTAAATGAAGTATT
AAAGCAAGCGAAGCGTCAAGATTTAGAACAATTAAAAGCTGTATGGGGTGAGTTGTTAGGAAGGCTCAAATCATACAATA
AAGTGGCGTTTGCCGTTTTGTTAGAAAATAGCGAACCAGTAGCGGCTTCGGATGATACTTACGTTTTAGCGTTCCAATAT
GAGATTCACTGTAAAATGCAAGCGAAAATCGAGAGGCTATGGATACAGTGGAACAAGCTTTATTTGAACTGCTAA

Upstream 100 bases:

>100_bases
ACTAAGGTGGGTTTTTTGTATAGAAAATAACTTTTGGAATCTATAAACAGAATGGGTTATAATAAATGAGATAATAACCT
TTGAGGGAGGCCGTATTTTC

Downstream 100 bases:

>100_bases
GTAAAAGATTAAATATGATTGCCATTCCGAAAAGTGAATGGGGTAAAATCCGTGAAGATTTTTTACAGCGTGAAGGCGGA
AGTTCTGAAGAAAGTCCAGA

Product: DNA polymerase iii subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL
GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH
KIPPTIISRCQRFEFRKISVNDIVERLSTVVNNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDETVTTEDVLAV
TGSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVMVDEQFRMLSEE
MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVPQE
VRETRAAPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQY
EIHCKMQAKIERLWIQWNKLYLNC

Sequences:

>Translated_504_residues
MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL
GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH
KIPPTIISRCQRFEFRKISVNDIVERLSTVVNNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDETVTTEDVLAV
TGSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVMVDEQFRMLSEE
MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVPQE
VRETRAAPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQY
EIHCKMQAKIERLWIQWNKLYLNC
>Mature_503_residues
SYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLG
ITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHK
IPPTIISRCQRFEFRKISVNDIVERLSTVVNNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDETVTTEDVLAVT
GSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVMVDEQFRMLSEEM
QPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVPQEV
RETRAAPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQYE
IHCKMQAKIERLWIQWNKLYLNC

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=266, Percent_Identity=27.0676691729323, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI194306571, Length=266, Percent_Identity=27.0676691729323, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI194306567, Length=266, Percent_Identity=27.0676691729323, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI31563534, Length=285, Percent_Identity=26.6666666666667, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI194306569, Length=186, Percent_Identity=28.494623655914, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4506491, Length=368, Percent_Identity=20.9239130434783, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI31881687, Length=368, Percent_Identity=20.9239130434783, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786676, Length=358, Percent_Identity=43.854748603352, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1787119, Length=233, Percent_Identity=26.6094420600858, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71986063, Length=295, Percent_Identity=24.0677966101695, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17554730, Length=222, Percent_Identity=27.027027027027, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17541988, Length=237, Percent_Identity=28.6919831223629, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6324039, Length=309, Percent_Identity=24.5954692556634, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6322528, Length=309, Percent_Identity=23.3009708737864, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324478, Length=239, Percent_Identity=25.1046025104602, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI18859927, Length=290, Percent_Identity=22.4137931034483, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17647857, Length=314, Percent_Identity=25.4777070063694, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19921076, Length=237, Percent_Identity=25.3164556962025, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 57411; Mature: 57280

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAK
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
AINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEY
HHCCCCCCCCCHHHHCHHHHCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCEEE
KVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISV
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCHHHCCCH
NDIVERLSTVVNNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDETVTTEDVLAV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
TGSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHH
LEHMLERVMVDEQFRMLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
FMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVPQEVRETRAAPKPVRTGSMKIPV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEECCH
GRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCEEEEEEE
EIHCKMQAKIERLWIQWNKLYLNC
EEEEHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
SYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAK
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
AINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEY
HHCCCCCCCCCHHHHCHHHHCCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCEEE
KVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISV
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCHHHCCCH
NDIVERLSTVVNNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDETVTTEDVLAV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
TGSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHH
LEHMLERVMVDEQFRMLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
FMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVPQEVRETRAAPKPVRTGSMKIPV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEECCH
GRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCEEEEEEE
EIHCKMQAKIERLWIQWNKLYLNC
EEEEHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]