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The map label for this gene is dgk [H]

Identifier: 222093789

GI number: 222093789

Start: 23135

End: 23770

Strand: Reverse

Name: dgk [H]

Synonym: BCQ_0022

Alternate gene names: 222093789

Gene position: 23770-23135 (Counterclockwise)

Preceding gene: 222093790

Following gene: 222093788

Centisome position: 0.46

GC content: 34.91

Gene sequence:

>636_bases
GTGACCGGAGTACCATTTATCACGGTTGAAGGACCAATTGGTGTTGGAAAAACTTCACTTGCGAAGGAAATTTCAACTCA
CATGCAACTCCACTTACTGAAAGAGATTGTTGATGAAAACCCCTTTTTAGGAAAGTTCTATGAAGACATCGACGAATGGA
GTTTTCAAACAGAGATGTTCTTTCTTTGTAATAGATACAAACAATTAGAAGATATTAACATAAAGTATTTGAATCAAAGG
AAGCCAGTAGTAGCGGACTACCATATATTCAAAAACGTAATTTTCGCATCCCGTACATTAAAAGATTCTCAATATGACAA
GTACATGCAAATCTATCGTATCCTTACACAAGATATGCCTGTTCCAAACGTTATCGTTTATTTAACAGCTAGCTTAGAAA
CATTACAAAAGCGAATCGCAATGCGCGGAAGAGAATTCGAAAAAAATATGGATCCAAATTACTTACTACAGCTCACAAAA
GATTACGAAACAGCAATGGATGCTTTTAAAAAAGACCATCCAGATATCCCAGTATTGAAATTTAATGGAGACGATATGGA
TTTTGTAAAAAATCCTGATGATTTAAACGTCATCCTATCTGCCCTTCAAAATACTCTCTTAAAGGAGTCGAAATAA

Upstream 100 bases:

>100_bases
TATATCAAATTAACCCGCTCGCTTCCCTCTTGTGCTACAATAATTCTGTTTTGTGTTTTTAGTAGTCACGGTAAATCACT
GATTGAAAGGAGGAAACAGC

Downstream 100 bases:

>100_bases
TAATGAATTTAAGGCAAAAATATGATATCCCAAATGACGCAGTAATCACTATCGCTGGAACAGTAGGTGTCGGTAAATCC
ACTATGACAACTGCATTAGC

Product: deoxyguanosine kinase

Products: NA

Alternate protein names: DGUO kinase; dGK [H]

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMFFLCNRYKQLEDINIKYLNQR
KPVVADYHIFKNVIFASRTLKDSQYDKYMQIYRILTQDMPVPNVIVYLTASLETLQKRIAMRGREFEKNMDPNYLLQLTK
DYETAMDAFKKDHPDIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK

Sequences:

>Translated_211_residues
MTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMFFLCNRYKQLEDINIKYLNQR
KPVVADYHIFKNVIFASRTLKDSQYDKYMQIYRILTQDMPVPNVIVYLTASLETLQKRIAMRGREFEKNMDPNYLLQLTK
DYETAMDAFKKDHPDIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK
>Mature_210_residues
TGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMFFLCNRYKQLEDINIKYLNQRK
PVVADYHIFKNVIFASRTLKDSQYDKYMQIYRILTQDMPVPNVIVYLTASLETLQKRIAMRGREFEKNMDPNYLLQLTKD
YETAMDAFKKDHPDIPVLKFNGDDMDFVKNPDDLNVILSALQNTLLKESK

Specific function: Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism. Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno). Only marginal activity is observed with guanosine. UTP is slightly more efficient as ph

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24689; Mature: 24558

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
FLCNRYKQLEDINIKYLNQRKPVVADYHIFKNVIFASRTLKDSQYDKYMQIYRILTQDMP
HHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
VPNVIVYLTASLETLQKRIAMRGREFEKNMDPNYLLQLTKDYETAMDAFKKDHPDIPVLK
CCCEEEEEHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
FNGDDMDFVKNPDDLNVILSALQNTLLKESK
ECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TGVPFITVEGPIGVGKTSLAKEISTHMQLHLLKEIVDENPFLGKFYEDIDEWSFQTEMF
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
FLCNRYKQLEDINIKYLNQRKPVVADYHIFKNVIFASRTLKDSQYDKYMQIYRILTQDMP
HHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
VPNVIVYLTASLETLQKRIAMRGREFEKNMDPNYLLQLTKDYETAMDAFKKDHPDIPVLK
CCCEEEEEHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
FNGDDMDFVKNPDDLNVILSALQNTLLKESK
ECCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]