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The map label for this gene is pdx1 [H]

Identifier: 222093784

GI number: 222093784

Start: 18522

End: 19409

Strand: Direct

Name: pdx1 [H]

Synonym: BCQ_0016

Alternate gene names: 222093784

Gene position: 18522-19409 (Clockwise)

Preceding gene: 222093783

Following gene: 222093785

Centisome position: 0.36

GC content: 43.36

Gene sequence:

>888_bases
ATGACAAATGTAACAGGGACAGAACGTGTAAAACGTGGAATGGCAGAAATGCAAAAAGGCGGCGTTATTATGGACGTAAT
TAACGCTGAACAAGCAAAAATTGCAGAAGAGGCAGGCGCAGTTGCCGTTATGGCATTAGAGCGTGTACCAGCAGATATTC
GTGCAGCAGGTGGCGTTTCTCGTATGGCAGACCCAACAATTGTTGAAGAAGTTATGGGTGCAGTGTCAATTCCGGTTATG
GCAAAATGCCGTATCGGTCACCTTGTAGAAGCACGTGTATTAGAATCATTAGGGGTAGACTATATCGATGAGAGTGAAGT
ATTAACTCCAGCAGATGAAGTATACCATTTAAATAAACGTGATTACACAGTTCCATTTGTATGTGGTTGCCGTGATATCG
GAGAAGCTGCACGTCGTATTGCAGAAGGTGCATCTATGCTTCGTACAAAAGGCGAACCAGGAACAGGAAACATTGTAGAG
GCAGTGCGTCATATGCGTCAAGTCAATGCAGAAATCCGTCAAGTTGCAAGTCTACGTGAAGATGAGTTAATGACATATGC
AAAAAATACTGGTGCTCCTTATGAAGTACTACGTGAAATTAAACGCCTTGGTCGTTTGCCGGTTGTAAACTTTGCAGCAG
GTGGTGTAGCAACACCAGCAGATGCAGCGTTAATGATGCAACTTGGTGCGGATGGTGTATTTGTTGGATCTGGTATCTTT
AAATCAGAGAATCCAGCGAAATTTGCACGTGCAATCGTTGAAGCGACAACTCATTATGAGGATTACGAGTTAATTGCAAG
CCTTTCTAAAGGACTAGGTAATGCGATGAAAGGTATTGAAATTTCAACGTTACTACCAGAGCAACGCATGCAAGAGCGTG
GATGGTAA

Upstream 100 bases:

>100_bases
TAGTAGACAAGCATCTGATAGTTAGTGGTAGAATGTAAGAGTATTCTTAATTTTCGCCTTTAACGGGGAAAAGCAATTCA
CCTAGGGGGGTTTTTGTAAC

Downstream 100 bases:

>100_bases
TTGAAGGAGAACTTTAAAATGGTGAAAATCGGTGTACTAGGTCTTCAAGGTGCAGTTCGTGAACATGTAAAATCAGTTGA
AGCAAGTGGTGCAGAAGCTG

Product: pyridoxal biosynthesis lyase pdxs

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MTNVTGTERVKRGMAEMQKGGVIMDVINAEQAKIAEEAGAVAVMALERVPADIRAAGGVSRMADPTIVEEVMGAVSIPVM
AKCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKRDYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVE
AVRHMRQVNAEIRQVASLREDELMTYAKNTGAPYEVLREIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIF
KSENPAKFARAIVEATTHYEDYELIASLSKGLGNAMKGIEISTLLPEQRMQERGW

Sequences:

>Translated_295_residues
MTNVTGTERVKRGMAEMQKGGVIMDVINAEQAKIAEEAGAVAVMALERVPADIRAAGGVSRMADPTIVEEVMGAVSIPVM
AKCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKRDYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVE
AVRHMRQVNAEIRQVASLREDELMTYAKNTGAPYEVLREIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIF
KSENPAKFARAIVEATTHYEDYELIASLSKGLGNAMKGIEISTLLPEQRMQERGW
>Mature_294_residues
TNVTGTERVKRGMAEMQKGGVIMDVINAEQAKIAEEAGAVAVMALERVPADIRAAGGVSRMADPTIVEEVMGAVSIPVMA
KCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKRDYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVEA
VRHMRQVNAEIRQVASLREDELMTYAKNTGAPYEVLREIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFK
SENPAKFARAIVEATTHYEDYELIASLSKGLGNAMKGIEISTLLPEQRMQERGW

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring [H]

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=291, Percent_Identity=56.701030927835, Blast_Score=348, Evalue=5e-97,
Organism=Saccharomyces cerevisiae, GI6323996, Length=294, Percent_Identity=58.5034013605442, Blast_Score=341, Evalue=8e-95,
Organism=Saccharomyces cerevisiae, GI6321049, Length=294, Percent_Identity=58.5034013605442, Blast_Score=341, Evalue=9e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852 [H]

Pfam domain/function: PF01680 SOR_SNZ [H]

EC number: NA

Molecular weight: Translated: 31833; Mature: 31702

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01235 PDXS_SNZ_1 ; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVTGTERVKRGMAEMQKGGVIMDVINAEQAKIAEEAGAVAVMALERVPADIRAAGGVS
CCCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCHHHHHHHHHCCHHHHHHCCCH
RMADPTIVEEVMGAVSIPVMAKCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKR
HCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEECCCC
DYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVEAVRHMRQVNAEIRQVASLRE
CCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DELMTYAKNTGAPYEVLREIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIF
HHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCC
KSENPAKFARAIVEATTHYEDYELIASLSKGLGNAMKGIEISTLLPEQRMQERGW
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHCCC
>Mature Secondary Structure 
TNVTGTERVKRGMAEMQKGGVIMDVINAEQAKIAEEAGAVAVMALERVPADIRAAGGVS
CCCCHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCHHHHHHHHHCCHHHHHHCCCH
RMADPTIVEEVMGAVSIPVMAKCRIGHLVEARVLESLGVDYIDESEVLTPADEVYHLNKR
HCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEECCCC
DYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVEAVRHMRQVNAEIRQVASLRE
CCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DELMTYAKNTGAPYEVLREIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIF
HHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCC
KSENPAKFARAIVEATTHYEDYELIASLSKGLGNAMKGIEISTLLPEQRMQERGW
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA