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The map label for this gene is pqqE [H]

Identifier: 221636246

GI number: 221636246

Start: 825134

End: 826231

Strand: Reverse

Name: pqqE [H]

Synonym: trd_A0840

Alternate gene names: 221636246

Gene position: 826231-825134 (Counterclockwise)

Preceding gene: 221636247

Following gene: 221636245

Centisome position: 90.03

GC content: 62.2

Gene sequence:

>1098_bases
ATGTGGACTGAGGTGCTCCGCCGCGGATTGGCTGCGCCGATCTGTCTGACCTGGGAGATCACCTACGCCTGCAATTTCAA
CTGTGTGCACTGTTTGTCCTCGTCGGGGAAGCGTGCGTCGGACGAGCTCACGACCGAGGAAGCGAAGCGCTTGATCGACG
AGTGGGCGGCTCTCCGAGTGTTTTACATCAACGTCGGAGGTGGTGAGCCGCTCCTCCGACCGGATTTTGTCGAACTGATG
GAATATGCCATCGCGCGGGGCATCGGGGTGAAATTCAGCACCAATGGGAGCTTGATCGACGAAGCGGTGGCGGACTGGAT
CGCGCGGACGCCATATCTCGACGTACAGATCAGCCTCGATGGTGTGACAGCGGAGGTGAACGATGCGATCCGTGGCGCTG
GCTCGTATGCACTAGCCCGACGCGCGATGGATTTCCTCGCAGCGCGAGGCTTTTCGTTCAAGATCAACGCCGTGTTGACC
AGGCGGAACTTCGAGCAATTGGATGACTTCTACGCGCTCGCCACGTCGTACGGTGCGCAATTGCGGGTGACACGACTGCG
CCCTTCGGGGCGTGGTCGTGCGGTATGGAACGAACTGCGGCTGACACGTGCGCAGAGCCACCAGCTGTACGAGTGGCTCC
TCCAGCATCCGGATGTTCTGACGGGTGACTCGTTCTTTCATCTATCCGCCCTCGGACAGCCGCTCGATGGCCTCAACATG
TGTGGTGCAGGGCGGATTGTCTGCTGCGTCGATCCGCGTGGAGACGTCTATGCCTGTCCGTTCGTGCTGACCGAAGAGTT
CAAGGCGGGAAACGTTCGCGAGCGGTCGTTCACCGAGATTTGGCGCCACTCGCCGCTCTTCCGTCGGTTGCGCGAGTGGG
AAGCTGGCTCGACCTGCCAGCAGTGCTCGGCCTACGCGCGCTGCCAAAGCGGGTGCTTCGCGGTCAAGTACTTCACCGGT
ACGCCGCTCGAGGCACCGGATCCTGAATGTGTGTTTGCACCGGAAACTGGTCCGACCGATGTCGTGTTGCCGCTCCGCGT
GCACCCGAGGCCGGTCCGGAGCCCGCGTCGTGCGGCGGTCGTCCCCGCGGCGCGATAA

Upstream 100 bases:

>100_bases
GAGATGGCGCAACGCCTCGCGGCGGCTGGCCAGTTGCCGGACGACGCGTTGGGGAAGCTCCTCCCGCTCCTGGAGGGGCT
GCGCCGGAGGGGGGTCGTCG

Downstream 100 bases:

>100_bases
CGGCGATTCTGGTTCCGTGCGCCAAGGCCGAAGTTCCATGGCGAGCGCGAAGGAATTAGGCAGTATCGGTCGCATACGCC
ATGATCCGGAGCCCGCAGGC

Product: radical SAM domain protein

Products: NA

Alternate protein names: Pyrroloquinoline quinone biosynthesis protein E [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MWTEVLRRGLAAPICLTWEITYACNFNCVHCLSSSGKRASDELTTEEAKRLIDEWAALRVFYINVGGGEPLLRPDFVELM
EYAIARGIGVKFSTNGSLIDEAVADWIARTPYLDVQISLDGVTAEVNDAIRGAGSYALARRAMDFLAARGFSFKINAVLT
RRNFEQLDDFYALATSYGAQLRVTRLRPSGRGRAVWNELRLTRAQSHQLYEWLLQHPDVLTGDSFFHLSALGQPLDGLNM
CGAGRIVCCVDPRGDVYACPFVLTEEFKAGNVRERSFTEIWRHSPLFRRLREWEAGSTCQQCSAYARCQSGCFAVKYFTG
TPLEAPDPECVFAPETGPTDVVLPLRVHPRPVRSPRRAAVVPAAR

Sequences:

>Translated_365_residues
MWTEVLRRGLAAPICLTWEITYACNFNCVHCLSSSGKRASDELTTEEAKRLIDEWAALRVFYINVGGGEPLLRPDFVELM
EYAIARGIGVKFSTNGSLIDEAVADWIARTPYLDVQISLDGVTAEVNDAIRGAGSYALARRAMDFLAARGFSFKINAVLT
RRNFEQLDDFYALATSYGAQLRVTRLRPSGRGRAVWNELRLTRAQSHQLYEWLLQHPDVLTGDSFFHLSALGQPLDGLNM
CGAGRIVCCVDPRGDVYACPFVLTEEFKAGNVRERSFTEIWRHSPLFRRLREWEAGSTCQQCSAYARCQSGCFAVKYFTG
TPLEAPDPECVFAPETGPTDVVLPLRVHPRPVRSPRRAAVVPAAR
>Mature_365_residues
MWTEVLRRGLAAPICLTWEITYACNFNCVHCLSSSGKRASDELTTEEAKRLIDEWAALRVFYINVGGGEPLLRPDFVELM
EYAIARGIGVKFSTNGSLIDEAVADWIARTPYLDVQISLDGVTAEVNDAIRGAGSYALARRAMDFLAARGFSFKINAVLT
RRNFEQLDDFYALATSYGAQLRVTRLRPSGRGRAVWNELRLTRAQSHQLYEWLLQHPDVLTGDSFFHLSALGQPLDGLNM
CGAGRIVCCVDPRGDVYACPFVLTEEFKAGNVRERSFTEIWRHSPLFRRLREWEAGSTCQQCSAYARCQSGCFAVKYFTG
TPLEAPDPECVFAPETGPTDVVLPLRVHPRPVRSPRRAAVVPAAR

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG0535

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. PqqE family [H]

Homologues:

Organism=Escherichia coli, GI1786999, Length=197, Percent_Identity=30.4568527918782, Blast_Score=73, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR000385
- InterPro:   IPR017200
- InterPro:   IPR011843
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 40750; Mature: 40750

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00153 ATPASE_GAMMA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWTEVLRRGLAAPICLTWEITYACNFNCVHCLSSSGKRASDELTTEEAKRLIDEWAALRV
CCHHHHHHCCCCCEEEEEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEE
FYINVGGGEPLLRPDFVELMEYAIARGIGVKFSTNGSLIDEAVADWIARTPYLDVQISLD
EEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEEC
GVTAEVNDAIRGAGSYALARRAMDFLAARGFSFKINAVLTRRNFEQLDDFYALATSYGAQ
CCEEHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCE
LRVTRLRPSGRGRAVWNELRLTRAQSHQLYEWLLQHPDVLTGDSFFHLSALGQPLDGLNM
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEHHHCCCCCCCCCC
CGAGRIVCCVDPRGDVYACPFVLTEEFKAGNVRERSFTEIWRHSPLFRRLREWEAGSTCQ
CCCCCEEEEECCCCCEEECCEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHH
QCSAYARCQSGCFAVKYFTGTPLEAPDPECVFAPETGPTDVVLPLRVHPRPVRSPRRAAV
HHHHHHHHCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCEEC
VPAAR
CCCCC
>Mature Secondary Structure
MWTEVLRRGLAAPICLTWEITYACNFNCVHCLSSSGKRASDELTTEEAKRLIDEWAALRV
CCHHHHHHCCCCCEEEEEEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEEE
FYINVGGGEPLLRPDFVELMEYAIARGIGVKFSTNGSLIDEAVADWIARTPYLDVQISLD
EEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCEEEEEEEC
GVTAEVNDAIRGAGSYALARRAMDFLAARGFSFKINAVLTRRNFEQLDDFYALATSYGAQ
CCEEHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCE
LRVTRLRPSGRGRAVWNELRLTRAQSHQLYEWLLQHPDVLTGDSFFHLSALGQPLDGLNM
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEHHHCCCCCCCCCC
CGAGRIVCCVDPRGDVYACPFVLTEEFKAGNVRERSFTEIWRHSPLFRRLREWEAGSTCQ
CCCCCEEEEECCCCCEEECCEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHCCCCCHHH
QCSAYARCQSGCFAVKYFTGTPLEAPDPECVFAPETGPTDVVLPLRVHPRPVRSPRRAAV
HHHHHHHHCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCEEEEEEECCCCCCCCCCEEC
VPAAR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA