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The map label for this gene is murQ [H]

Identifier: 221636119

GI number: 221636119

Start: 703894

End: 704811

Strand: Reverse

Name: murQ [H]

Synonym: trd_A0713

Alternate gene names: 221636119

Gene position: 704811-703894 (Counterclockwise)

Preceding gene: 221636120

Following gene: 221636118

Centisome position: 76.8

GC content: 70.59

Gene sequence:

>918_bases
ATGGACGAGCAGGACGAGCTGCGGCAGGCAACGACCGAGTCGGTGAACCCGCGGACGCGGCAGATCGACCAGCTCTCGAG
CCAGGCGATCGTGGAGTTGATCCTGGAGGAAGAGACGCGGGTGATTCCGGCAGTGCTGGCCGAGCGGACTGCCATCGCCG
CACTGGCGGACGTGGTCGTCGAGCGGATGCGCCGGGGTGGGCGCCTGGTCTACGTCGGTGCTGGGACGTCCGGCCGGTTG
GGGATGCTGGATGCCATCGAGTGCATCCCGACCTACGGGTTGGAGCCGGGTCGGATCGTCGCGCTGGTCGCTGGCGGGCC
GGCGGCGCTGACCGGACCGGTCGAGGCTGCCGAGGACGACGAGGAGGCGGGCGCGCGCGAGCTGACTGCGCTGGGCATCG
GGCCGGATGACGTCGTGCTCGGGATCAGCGCGAGCGGACGGACGCCCTACGTGCGCGGGGCGCTCCGCGAAGCGCGGCAG
CGTGGCGCCTACGTGGCCGTGCTCGTGTGCAATCGGCCCGCGCCGCTGGCCGATCTGGCTGACTTGGTGATCGCGCCGGT
CGTCGGCCCGGAGGTGATCGCTGGCTCGACCCGCATGAAGGCCGGGACGGCCCAGAAGCTTGTGCTCACTGCTTTGAGCA
CGACGGTGATGGTGCGGCTGGGTAAGACGTTCGGGAACCTGATGGTCGATGTGCGACCCACGAACCGCAAGCTCTGGCAG
CGCGGGGTGCGCATCGTGATGGAGGCGACTGGACTCAGCGAGCAGGATGCGCAGCGCGTGCTCCAGGAGGCGGGCGGCGA
GCCGAAGACGGCGATCGTGATGGCGATCGCGGGAGTCGATGCTGCAGAAGCCCGGTCGCGGCTCGGACGTGCCGGTGGGC
TCGTGCGGGCCGCCCTCGAGGAGAGCGATGGCGGCTGA

Upstream 100 bases:

>100_bases
CGCTGCAGGTGCGGTTTCGGCAGTCAGGCGCAGGGGTCGACCAGTCCGAGCGATTGCCGGGTTTTTCACTTTCGGCCGGT
GGCAGGAGCGGAGCGGACGG

Downstream 100 bases:

>100_bases
GCTTCTGCTCGGGATCGATGGTGGCGGGAGCACGACCCGCGCGGCGCTGGCTGACGCGCAGGGAAGAATCCTCGGCGTCG
GGACGACCGGCTCGAGCAAT

Product: N-acetylmuramic acid 6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDEQDELRQATTESVNPRTRQIDQLSSQAIVELILEEETRVIPAVLAERTAIAALADVVVERMRRGGRLVYVGAGTSGRL
GMLDAIECIPTYGLEPGRIVALVAGGPAALTGPVEAAEDDEEAGARELTALGIGPDDVVLGISASGRTPYVRGALREARQ
RGAYVAVLVCNRPAPLADLADLVIAPVVGPEVIAGSTRMKAGTAQKLVLTALSTTVMVRLGKTFGNLMVDVRPTNRKLWQ
RGVRIVMEATGLSEQDAQRVLQEAGGEPKTAIVMAIAGVDAAEARSRLGRAGGLVRAALEESDGG

Sequences:

>Translated_305_residues
MDEQDELRQATTESVNPRTRQIDQLSSQAIVELILEEETRVIPAVLAERTAIAALADVVVERMRRGGRLVYVGAGTSGRL
GMLDAIECIPTYGLEPGRIVALVAGGPAALTGPVEAAEDDEEAGARELTALGIGPDDVVLGISASGRTPYVRGALREARQ
RGAYVAVLVCNRPAPLADLADLVIAPVVGPEVIAGSTRMKAGTAQKLVLTALSTTVMVRLGKTFGNLMVDVRPTNRKLWQ
RGVRIVMEATGLSEQDAQRVLQEAGGEPKTAIVMAIAGVDAAEARSRLGRAGGLVRAALEESDGG
>Mature_305_residues
MDEQDELRQATTESVNPRTRQIDQLSSQAIVELILEEETRVIPAVLAERTAIAALADVVVERMRRGGRLVYVGAGTSGRL
GMLDAIECIPTYGLEPGRIVALVAGGPAALTGPVEAAEDDEEAGARELTALGIGPDDVVLGISASGRTPYVRGALREARQ
RGAYVAVLVCNRPAPLADLADLVIAPVVGPEVIAGSTRMKAGTAQKLVLTALSTTVMVRLGKTFGNLMVDVRPTNRKLWQ
RGVRIVMEATGLSEQDAQRVLQEAGGEPKTAIVMAIAGVDAAEARSRLGRAGGLVRAALEESDGG

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=296, Percent_Identity=47.6351351351351, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31976; Mature: 31976

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEQDELRQATTESVNPRTRQIDQLSSQAIVELILEEETRVIPAVLAERTAIAALADVVV
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERMRRGGRLVYVGAGTSGRLGMLDAIECIPTYGLEPGRIVALVAGGPAALTGPVEAAEDD
HHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCCCCCC
EEAGARELTALGIGPDDVVLGISASGRTPYVRGALREARQRGAYVAVLVCNRPAPLADLA
HHCCCHHEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
DLVIAPVVGPEVIAGSTRMKAGTAQKLVLTALSTTVMVRLGKTFGNLMVDVRPTNRKLWQ
HHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHH
RGVRIVMEATGLSEQDAQRVLQEAGGEPKTAIVMAIAGVDAAEARSRLGRAGGLVRAALE
HHHEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHCCHHHHHHH
ESDGG
CCCCC
>Mature Secondary Structure
MDEQDELRQATTESVNPRTRQIDQLSSQAIVELILEEETRVIPAVLAERTAIAALADVVV
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERMRRGGRLVYVGAGTSGRLGMLDAIECIPTYGLEPGRIVALVAGGPAALTGPVEAAEDD
HHHHCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCCCCCC
EEAGARELTALGIGPDDVVLGISASGRTPYVRGALREARQRGAYVAVLVCNRPAPLADLA
HHCCCHHEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCHHHHH
DLVIAPVVGPEVIAGSTRMKAGTAQKLVLTALSTTVMVRLGKTFGNLMVDVRPTNRKLWQ
HHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHH
RGVRIVMEATGLSEQDAQRVLQEAGGEPKTAIVMAIAGVDAAEARSRLGRAGGLVRAALE
HHHEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHCCHHHHHHH
ESDGG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA